Low Molecular Weight Mannogalactofucans Derived from Undaria pinnatifida Induce Apoptotic Death of Human Prostate Cancer Cells In Vitro and In ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-12

AUTHORS

Jisun Lee, Seul Lee, Andriy Synytsya, Peter Capek, Chang Won Lee, Ji Won Choi, Sarang Cho, Woo Jung Kim, Yong Il Park

ABSTRACT

Low molecular weight mannogalactofucans (LMMGFs) prepared by enzymatic degradation of high molecular weight Undaria galactofucan (MF) were evaluated for their anti-cancer effects against human prostate cancer. Correlation NMR and linkage analyses confirmed that LMMGFs consist mainly of α-fucose and β-galactose units: α-fucose units are 1,3-linked; β-galactose units are terminal, 1,3- and/or 1,6-linked; both sugars are partially sulphated, fucose at positions O-2 and/or O-4 and galactose at O-3. Mannose residue, as a minor sugar, presents as the 1,4-linked terminal units. LMMGFs more significantly induced cell cycle arrest at the G0/G1 phase and cell death via suppression of the Akt/GSK-3β/β-catenin pathway than MF in human PC-3 prostate cancer cells. LMMGFs upregulated mRNA expression of death receptor-5 (DR-5), the ratio of Bax to Bcl-2, the cleavage of caspases and PARP, the depolarisation of mitochondrial membrane potential, and ROS generation. LMMGFs (200-400 mg/kg) effectively reduced both tumour volume and size in a xenografted mouse model. These results demonstrated that LMMGFs attenuate the growth of human prostate cancer cells both in vitro and in vivo, suggesting that LMMGFs can be used as a potent functional ingredient in health-beneficial foods or as a therapeutic agent to prevent or treat androgen-independent human prostate cancer. Graphical Abstract. More... »

PAGES

1-16

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10126-018-9851-3

DOI

http://dx.doi.org/10.1007/s10126-018-9851-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1106409963

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30159630


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Catholic University of Korea", 
          "id": "https://www.grid.ac/institutes/grid.411947.e", 
          "name": [
            "Department of Biotechnology, The Catholic University of Korea, 14662, Bucheon, Gyeonggi-do, South Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lee", 
        "givenName": "Jisun", 
        "id": "sg:person.01041615435.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01041615435.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Catholic University of Korea", 
          "id": "https://www.grid.ac/institutes/grid.411947.e", 
          "name": [
            "Department of Biotechnology, The Catholic University of Korea, 14662, Bucheon, Gyeonggi-do, South Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lee", 
        "givenName": "Seul", 
        "id": "sg:person.0716260774.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716260774.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Chemistry and Technology", 
          "id": "https://www.grid.ac/institutes/grid.448072.d", 
          "name": [
            "Department of Carbohydrate Chemistry and Technology, University of Chemical Technology in Prague, Technick\u00e1 5, 166 28, Prague 6, Czech Republic"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Synytsya", 
        "givenName": "Andriy", 
        "id": "sg:person.01234722214.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01234722214.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Chemistry", 
          "id": "https://www.grid.ac/institutes/grid.22539.3f", 
          "name": [
            "Institute of Chemistry, Centre for Glycomics, Slovak Academy of Sciences, D\u00fabravsk\u00e1 cesta 9, 845 38, Bratislava, Slovakia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Capek", 
        "givenName": "Peter", 
        "id": "sg:person.0622607506.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622607506.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Catholic University of Korea", 
          "id": "https://www.grid.ac/institutes/grid.411947.e", 
          "name": [
            "Department of Biotechnology, The Catholic University of Korea, 14662, Bucheon, Gyeonggi-do, South Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lee", 
        "givenName": "Chang Won", 
        "id": "sg:person.0600622642.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600622642.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Catholic University of Korea", 
          "id": "https://www.grid.ac/institutes/grid.411947.e", 
          "name": [
            "Department of Biotechnology, The Catholic University of Korea, 14662, Bucheon, Gyeonggi-do, South Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Choi", 
        "givenName": "Ji Won", 
        "id": "sg:person.0715051242.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0715051242.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Catholic University of Korea", 
          "id": "https://www.grid.ac/institutes/grid.411947.e", 
          "name": [
            "Department of Biotechnology, The Catholic University of Korea, 14662, Bucheon, Gyeonggi-do, South Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cho", 
        "givenName": "Sarang", 
        "id": "sg:person.0631274641.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631274641.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Biocenter, Gyeonggido Business and Science Accelerator (GBSA), 16229, Suwon, Gyeonggi-do, South Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Woo Jung", 
        "id": "sg:person.01161612747.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01161612747.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Catholic University of Korea", 
          "id": "https://www.grid.ac/institutes/grid.411947.e", 
          "name": [
            "Department of Biotechnology, The Catholic University of Korea, 14662, Bucheon, Gyeonggi-do, South Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Park", 
        "givenName": "Yong Il", 
        "id": "sg:person.01372306062.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372306062.28"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1124/jpet.102.046144", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000290868"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/01635581.2013.757628", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000432584"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/md12020851", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000673102"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12272-010-2234-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001477953", 
          "https://doi.org/10.1007/s12272-010-2234-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12272-010-2234-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001477953", 
          "https://doi.org/10.1007/s12272-010-2234-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0008-6215(02)00053-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004088817"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.lfs.2014.10.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004578958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-07-0717", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004618535"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jbm.a.31819", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005060137"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13205-012-0061-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005408703", 
          "https://doi.org/10.1007/s13205-012-0061-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18632/oncotarget.2317", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006630880"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/mcbr.2001.0265", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007686286"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc883", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008451806", 
          "https://doi.org/10.1038/nrc883"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc883", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008451806", 
          "https://doi.org/10.1038/nrc883"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3322/caac.20107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009055747"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.canlet.2008.06.032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009956034"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.carbpol.2010.01.052", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011881625"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1124/mol.64.3.696", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012074048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0027441", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014958081"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10126-015-9643-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015084432", 
          "https://doi.org/10.1007/s10126-015-9643-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0043483", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016150674"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.carres.2003.10.028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017103819"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/01926230701320337", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017477247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/01926230701320337", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017477247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/md13074398", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020249298"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.20670", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020306323"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijbiomac.2008.08.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025054169"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00018-007-7045-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025201509", 
          "https://doi.org/10.1007/s00018-007-7045-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1186/1750-2187-2-10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026157427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/md14070126", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026505498"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pros.20126", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028173969"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jcb.21603", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028753974"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejca.2011.04.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029491629"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10811-006-9096-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029505482", 
          "https://doi.org/10.1007/s10811-006-9096-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.275.5303.1132", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030035967"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc2657", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031760843", 
          "https://doi.org/10.1038/nrc2657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc2657", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031760843", 
          "https://doi.org/10.1038/nrc2657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/carcin/bgs396", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033150093"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/sj.neo.7900203", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033316992"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1271/bbb.120631", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033663215"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pros.20069", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037749918"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/md9101731", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038745347"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/md11082982", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040488258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0094-0143(05)70339-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040891978"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0094-0143(05)70339-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040891978"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1271/bbb.63.1813", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042352010"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.1205304", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042626529"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.yexcr.2009.10.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044136427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m600686200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044616013"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0090-4295(97)00163-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047261397"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.carbpol.2014.05.032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049230486"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajh.20182", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049684417"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4490/algae.2007.22.3.247", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053672285"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/tx00026a012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056296736"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2006-951703", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057467196"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/abbs/gmv094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059352810"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a127869", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1076282982"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077646666", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijbiomac.2017.05.060", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085412416"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-12", 
    "datePublishedReg": "2018-12-01", 
    "description": "Low molecular weight mannogalactofucans (LMMGFs) prepared by enzymatic degradation of high molecular weight Undaria galactofucan (MF) were evaluated for their anti-cancer effects against human prostate cancer. Correlation NMR and linkage analyses confirmed that LMMGFs consist mainly of \u03b1-fucose and \u03b2-galactose units: \u03b1-fucose units are 1,3-linked; \u03b2-galactose units are terminal, 1,3- and/or 1,6-linked; both sugars are partially sulphated, fucose at positions O-2 and/or O-4 and galactose at O-3. Mannose residue, as a minor sugar, presents as the 1,4-linked terminal units. LMMGFs more significantly induced cell cycle arrest at the G0/G1 phase and cell death via suppression of the Akt/GSK-3\u03b2/\u03b2-catenin pathway than MF in human PC-3 prostate cancer cells. LMMGFs upregulated mRNA expression of death receptor-5 (DR-5), the ratio of Bax to Bcl-2, the cleavage of caspases and PARP, the depolarisation of mitochondrial membrane potential, and ROS generation. LMMGFs (200-400\u00a0mg/kg) effectively reduced both tumour volume and size in a xenografted mouse model. These results demonstrated that LMMGFs attenuate the growth of human prostate cancer cells both in vitro and in vivo, suggesting that LMMGFs can be used as a potent functional ingredient in health-beneficial foods or as a therapeutic agent to prevent or treat androgen-independent human prostate cancer. Graphical Abstract.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s10126-018-9851-3", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1021527", 
        "issn": [
          "1436-2228", 
          "1432-1408"
        ], 
        "name": "Journal of Marine Biotechnology", 
        "type": "Periodical"
      }
    ], 
    "name": "Low Molecular Weight Mannogalactofucans Derived from Undaria pinnatifida Induce Apoptotic Death of Human Prostate Cancer Cells In Vitro and In Vivo", 
    "pagination": "1-16", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "35adb502415ab5eb5dfa403b85d80c5929d7a2a1c4848fcaad1b059ebff3ca7e"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30159630"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100892712"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10126-018-9851-3"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1106409963"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10126-018-9851-3", 
      "https://app.dimensions.ai/details/publication/pub.1106409963"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T20:54", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8684_00000557.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs10126-018-9851-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10126-018-9851-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10126-018-9851-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10126-018-9851-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10126-018-9851-3'


 

This table displays all metadata directly associated to this object as RDF triples.

295 TRIPLES      21 PREDICATES      81 URIs      19 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10126-018-9851-3 schema:about anzsrc-for:11
2 anzsrc-for:1112
3 schema:author Ndbaa39969d854361b286949aa4c2bd3e
4 schema:citation sg:pub.10.1007/s00018-007-7045-7
5 sg:pub.10.1007/s10126-015-9643-y
6 sg:pub.10.1007/s10811-006-9096-9
7 sg:pub.10.1007/s12272-010-2234-6
8 sg:pub.10.1007/s13205-012-0061-9
9 sg:pub.10.1038/nrc2657
10 sg:pub.10.1038/nrc883
11 https://app.dimensions.ai/details/publication/pub.1077646666
12 https://doi.org/10.1002/ajh.20182
13 https://doi.org/10.1002/cncr.20670
14 https://doi.org/10.1002/jbm.a.31819
15 https://doi.org/10.1002/jcb.21603
16 https://doi.org/10.1002/pros.20069
17 https://doi.org/10.1002/pros.20126
18 https://doi.org/10.1006/mcbr.2001.0265
19 https://doi.org/10.1016/j.canlet.2008.06.032
20 https://doi.org/10.1016/j.carbpol.2010.01.052
21 https://doi.org/10.1016/j.carbpol.2014.05.032
22 https://doi.org/10.1016/j.carres.2003.10.028
23 https://doi.org/10.1016/j.ejca.2011.04.004
24 https://doi.org/10.1016/j.ijbiomac.2008.08.006
25 https://doi.org/10.1016/j.ijbiomac.2017.05.060
26 https://doi.org/10.1016/j.lfs.2014.10.012
27 https://doi.org/10.1016/j.yexcr.2009.10.012
28 https://doi.org/10.1016/s0008-6215(02)00053-8
29 https://doi.org/10.1016/s0090-4295(97)00163-5
30 https://doi.org/10.1016/s0094-0143(05)70339-6
31 https://doi.org/10.1021/tx00026a012
32 https://doi.org/10.1038/sj.neo.7900203
33 https://doi.org/10.1055/s-2006-951703
34 https://doi.org/10.1074/jbc.m600686200
35 https://doi.org/10.1080/01635581.2013.757628
36 https://doi.org/10.1080/01926230701320337
37 https://doi.org/10.1093/abbs/gmv094
38 https://doi.org/10.1093/carcin/bgs396
39 https://doi.org/10.1093/oxfordjournals.jbchem.a127869
40 https://doi.org/10.1101/gad.1205304
41 https://doi.org/10.1124/jpet.102.046144
42 https://doi.org/10.1124/mol.64.3.696
43 https://doi.org/10.1126/science.275.5303.1132
44 https://doi.org/10.1158/0008-5472.can-07-0717
45 https://doi.org/10.1186/1750-2187-2-10
46 https://doi.org/10.1271/bbb.120631
47 https://doi.org/10.1271/bbb.63.1813
48 https://doi.org/10.1371/journal.pone.0027441
49 https://doi.org/10.1371/journal.pone.0043483
50 https://doi.org/10.18632/oncotarget.2317
51 https://doi.org/10.3322/caac.20107
52 https://doi.org/10.3390/md11082982
53 https://doi.org/10.3390/md12020851
54 https://doi.org/10.3390/md13074398
55 https://doi.org/10.3390/md14070126
56 https://doi.org/10.3390/md9101731
57 https://doi.org/10.4490/algae.2007.22.3.247
58 schema:datePublished 2018-12
59 schema:datePublishedReg 2018-12-01
60 schema:description Low molecular weight mannogalactofucans (LMMGFs) prepared by enzymatic degradation of high molecular weight Undaria galactofucan (MF) were evaluated for their anti-cancer effects against human prostate cancer. Correlation NMR and linkage analyses confirmed that LMMGFs consist mainly of α-fucose and β-galactose units: α-fucose units are 1,3-linked; β-galactose units are terminal, 1,3- and/or 1,6-linked; both sugars are partially sulphated, fucose at positions O-2 and/or O-4 and galactose at O-3. Mannose residue, as a minor sugar, presents as the 1,4-linked terminal units. LMMGFs more significantly induced cell cycle arrest at the G0/G1 phase and cell death via suppression of the Akt/GSK-3β/β-catenin pathway than MF in human PC-3 prostate cancer cells. LMMGFs upregulated mRNA expression of death receptor-5 (DR-5), the ratio of Bax to Bcl-2, the cleavage of caspases and PARP, the depolarisation of mitochondrial membrane potential, and ROS generation. LMMGFs (200-400 mg/kg) effectively reduced both tumour volume and size in a xenografted mouse model. These results demonstrated that LMMGFs attenuate the growth of human prostate cancer cells both in vitro and in vivo, suggesting that LMMGFs can be used as a potent functional ingredient in health-beneficial foods or as a therapeutic agent to prevent or treat androgen-independent human prostate cancer. Graphical Abstract.
61 schema:genre research_article
62 schema:inLanguage en
63 schema:isAccessibleForFree false
64 schema:isPartOf sg:journal.1021527
65 schema:name Low Molecular Weight Mannogalactofucans Derived from Undaria pinnatifida Induce Apoptotic Death of Human Prostate Cancer Cells In Vitro and In Vivo
66 schema:pagination 1-16
67 schema:productId N09d824de352b4c5aa2a4fb09af6046c5
68 N1f9ac073378a424e9aefdf8cb7c2c270
69 N70fe5b4590cb460dac0ba6cef38c6789
70 N93ffbee007fc4173b2bbc4bf14f6cb0f
71 N9691d12e022942cfa4bb5c82b5b106b8
72 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106409963
73 https://doi.org/10.1007/s10126-018-9851-3
74 schema:sdDatePublished 2019-04-10T20:54
75 schema:sdLicense https://scigraph.springernature.com/explorer/license/
76 schema:sdPublisher Naaa3721ac02b42dc8bb79dc39d4727be
77 schema:url https://link.springer.com/10.1007%2Fs10126-018-9851-3
78 sgo:license sg:explorer/license/
79 sgo:sdDataset articles
80 rdf:type schema:ScholarlyArticle
81 N09d824de352b4c5aa2a4fb09af6046c5 schema:name pubmed_id
82 schema:value 30159630
83 rdf:type schema:PropertyValue
84 N10e251b7fba24f9492052399e215b9b7 rdf:first sg:person.01234722214.28
85 rdf:rest N8136a70a3ded4edb8495bcee09b113ed
86 N1f9ac073378a424e9aefdf8cb7c2c270 schema:name readcube_id
87 schema:value 35adb502415ab5eb5dfa403b85d80c5929d7a2a1c4848fcaad1b059ebff3ca7e
88 rdf:type schema:PropertyValue
89 N4600d9c9ff6e4d3980be62a200359903 rdf:first sg:person.0716260774.40
90 rdf:rest N10e251b7fba24f9492052399e215b9b7
91 N55d743e05e634982a3b0b40acb0a001d rdf:first sg:person.0715051242.18
92 rdf:rest Nee6533647be94a4e8e106459066d2c53
93 N70fe5b4590cb460dac0ba6cef38c6789 schema:name dimensions_id
94 schema:value pub.1106409963
95 rdf:type schema:PropertyValue
96 N8136a70a3ded4edb8495bcee09b113ed rdf:first sg:person.0622607506.43
97 rdf:rest Ncd957ef4c3c849079e3c70fe1906eda7
98 N84e9bfc247894a4a8a98615e716fc45f rdf:first sg:person.01372306062.28
99 rdf:rest rdf:nil
100 N93ffbee007fc4173b2bbc4bf14f6cb0f schema:name nlm_unique_id
101 schema:value 100892712
102 rdf:type schema:PropertyValue
103 N9691d12e022942cfa4bb5c82b5b106b8 schema:name doi
104 schema:value 10.1007/s10126-018-9851-3
105 rdf:type schema:PropertyValue
106 Naaa3721ac02b42dc8bb79dc39d4727be schema:name Springer Nature - SN SciGraph project
107 rdf:type schema:Organization
108 Nc6081ab3b90a43daa1fee65f3bbe9f25 schema:name Biocenter, Gyeonggido Business and Science Accelerator (GBSA), 16229, Suwon, Gyeonggi-do, South Korea
109 rdf:type schema:Organization
110 Ncd957ef4c3c849079e3c70fe1906eda7 rdf:first sg:person.0600622642.37
111 rdf:rest N55d743e05e634982a3b0b40acb0a001d
112 Ndbaa39969d854361b286949aa4c2bd3e rdf:first sg:person.01041615435.54
113 rdf:rest N4600d9c9ff6e4d3980be62a200359903
114 Nec0f6a2a8fd54211975ea572509a0d43 rdf:first sg:person.01161612747.75
115 rdf:rest N84e9bfc247894a4a8a98615e716fc45f
116 Nee6533647be94a4e8e106459066d2c53 rdf:first sg:person.0631274641.25
117 rdf:rest Nec0f6a2a8fd54211975ea572509a0d43
118 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
119 schema:name Medical and Health Sciences
120 rdf:type schema:DefinedTerm
121 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
122 schema:name Oncology and Carcinogenesis
123 rdf:type schema:DefinedTerm
124 sg:journal.1021527 schema:issn 1432-1408
125 1436-2228
126 schema:name Journal of Marine Biotechnology
127 rdf:type schema:Periodical
128 sg:person.01041615435.54 schema:affiliation https://www.grid.ac/institutes/grid.411947.e
129 schema:familyName Lee
130 schema:givenName Jisun
131 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01041615435.54
132 rdf:type schema:Person
133 sg:person.01161612747.75 schema:affiliation Nc6081ab3b90a43daa1fee65f3bbe9f25
134 schema:familyName Kim
135 schema:givenName Woo Jung
136 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01161612747.75
137 rdf:type schema:Person
138 sg:person.01234722214.28 schema:affiliation https://www.grid.ac/institutes/grid.448072.d
139 schema:familyName Synytsya
140 schema:givenName Andriy
141 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01234722214.28
142 rdf:type schema:Person
143 sg:person.01372306062.28 schema:affiliation https://www.grid.ac/institutes/grid.411947.e
144 schema:familyName Park
145 schema:givenName Yong Il
146 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372306062.28
147 rdf:type schema:Person
148 sg:person.0600622642.37 schema:affiliation https://www.grid.ac/institutes/grid.411947.e
149 schema:familyName Lee
150 schema:givenName Chang Won
151 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600622642.37
152 rdf:type schema:Person
153 sg:person.0622607506.43 schema:affiliation https://www.grid.ac/institutes/grid.22539.3f
154 schema:familyName Capek
155 schema:givenName Peter
156 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622607506.43
157 rdf:type schema:Person
158 sg:person.0631274641.25 schema:affiliation https://www.grid.ac/institutes/grid.411947.e
159 schema:familyName Cho
160 schema:givenName Sarang
161 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631274641.25
162 rdf:type schema:Person
163 sg:person.0715051242.18 schema:affiliation https://www.grid.ac/institutes/grid.411947.e
164 schema:familyName Choi
165 schema:givenName Ji Won
166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0715051242.18
167 rdf:type schema:Person
168 sg:person.0716260774.40 schema:affiliation https://www.grid.ac/institutes/grid.411947.e
169 schema:familyName Lee
170 schema:givenName Seul
171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716260774.40
172 rdf:type schema:Person
173 sg:pub.10.1007/s00018-007-7045-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025201509
174 https://doi.org/10.1007/s00018-007-7045-7
175 rdf:type schema:CreativeWork
176 sg:pub.10.1007/s10126-015-9643-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1015084432
177 https://doi.org/10.1007/s10126-015-9643-y
178 rdf:type schema:CreativeWork
179 sg:pub.10.1007/s10811-006-9096-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029505482
180 https://doi.org/10.1007/s10811-006-9096-9
181 rdf:type schema:CreativeWork
182 sg:pub.10.1007/s12272-010-2234-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001477953
183 https://doi.org/10.1007/s12272-010-2234-6
184 rdf:type schema:CreativeWork
185 sg:pub.10.1007/s13205-012-0061-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005408703
186 https://doi.org/10.1007/s13205-012-0061-9
187 rdf:type schema:CreativeWork
188 sg:pub.10.1038/nrc2657 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031760843
189 https://doi.org/10.1038/nrc2657
190 rdf:type schema:CreativeWork
191 sg:pub.10.1038/nrc883 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008451806
192 https://doi.org/10.1038/nrc883
193 rdf:type schema:CreativeWork
194 https://app.dimensions.ai/details/publication/pub.1077646666 schema:CreativeWork
195 https://doi.org/10.1002/ajh.20182 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049684417
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1002/cncr.20670 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020306323
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1002/jbm.a.31819 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005060137
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1002/jcb.21603 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028753974
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1002/pros.20069 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037749918
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1002/pros.20126 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028173969
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1006/mcbr.2001.0265 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007686286
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1016/j.canlet.2008.06.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009956034
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1016/j.carbpol.2010.01.052 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011881625
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1016/j.carbpol.2014.05.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049230486
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1016/j.carres.2003.10.028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017103819
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1016/j.ejca.2011.04.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029491629
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1016/j.ijbiomac.2008.08.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025054169
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1016/j.ijbiomac.2017.05.060 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085412416
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1016/j.lfs.2014.10.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004578958
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1016/j.yexcr.2009.10.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044136427
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1016/s0008-6215(02)00053-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004088817
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1016/s0090-4295(97)00163-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047261397
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1016/s0094-0143(05)70339-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040891978
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1021/tx00026a012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056296736
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1038/sj.neo.7900203 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033316992
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1055/s-2006-951703 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057467196
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1074/jbc.m600686200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044616013
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1080/01635581.2013.757628 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000432584
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1080/01926230701320337 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017477247
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1093/abbs/gmv094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059352810
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1093/carcin/bgs396 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033150093
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1093/oxfordjournals.jbchem.a127869 schema:sameAs https://app.dimensions.ai/details/publication/pub.1076282982
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1101/gad.1205304 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042626529
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1124/jpet.102.046144 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000290868
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1124/mol.64.3.696 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012074048
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1126/science.275.5303.1132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030035967
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1158/0008-5472.can-07-0717 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004618535
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1186/1750-2187-2-10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026157427
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1271/bbb.120631 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033663215
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1271/bbb.63.1813 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042352010
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1371/journal.pone.0027441 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014958081
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1371/journal.pone.0043483 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016150674
270 rdf:type schema:CreativeWork
271 https://doi.org/10.18632/oncotarget.2317 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006630880
272 rdf:type schema:CreativeWork
273 https://doi.org/10.3322/caac.20107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009055747
274 rdf:type schema:CreativeWork
275 https://doi.org/10.3390/md11082982 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040488258
276 rdf:type schema:CreativeWork
277 https://doi.org/10.3390/md12020851 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000673102
278 rdf:type schema:CreativeWork
279 https://doi.org/10.3390/md13074398 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020249298
280 rdf:type schema:CreativeWork
281 https://doi.org/10.3390/md14070126 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026505498
282 rdf:type schema:CreativeWork
283 https://doi.org/10.3390/md9101731 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038745347
284 rdf:type schema:CreativeWork
285 https://doi.org/10.4490/algae.2007.22.3.247 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053672285
286 rdf:type schema:CreativeWork
287 https://www.grid.ac/institutes/grid.22539.3f schema:alternateName Institute of Chemistry
288 schema:name Institute of Chemistry, Centre for Glycomics, Slovak Academy of Sciences, Dúbravská cesta 9, 845 38, Bratislava, Slovakia
289 rdf:type schema:Organization
290 https://www.grid.ac/institutes/grid.411947.e schema:alternateName Catholic University of Korea
291 schema:name Department of Biotechnology, The Catholic University of Korea, 14662, Bucheon, Gyeonggi-do, South Korea
292 rdf:type schema:Organization
293 https://www.grid.ac/institutes/grid.448072.d schema:alternateName University of Chemistry and Technology
294 schema:name Department of Carbohydrate Chemistry and Technology, University of Chemical Technology in Prague, Technická 5, 166 28, Prague 6, Czech Republic
295 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...