Ontology type: schema:ScholarlyArticle Open Access: True
2013-10
AUTHORSKensuke Shiraishi, Kousaku Mimura, Shinichiro Izawa, Ayako Inoue, Shugo Shiba, Takanori Maruyama, Mitsuaki Watanabe, Yoshihiko Kawaguchi, Masayuki Inoue, Hideki Fujii, Koji Kono
ABSTRACTBACKGROUND: Trastuzumab has been recently approved for clinical use to treat HER2-expressing advanced gastric cancer, and anti-HER2-targeting therapy has become a promising option for gastric cancer. Lapatinib is a dual tyrosine kinase inhibitor targeting EGFR and HER2. The aim of the present study was to explore the utility of lapatinib for gastric cancer, with a particular focus on trastuzumab-mediated antibody-dependent cellular cytotoxicity (ADCC). METHODS: Nine gastric cancer cell lines were evaluated for the effects of lapatinib on the cell-surface accumulation of HER2 and analyzed for their additional effects on trastuzumab-mediated ADCC. Also, HER2 signaling with Western blot, proliferative function with the MTT assay, and apoptosis-inducing activity with 7ADD/Annexin-V were investigated when a panel of gastric cancer cell lines was treated with lapatinib. RESULTS: Lapatinib inhibited HER2 signaling and cell proliferation in the panel of gastric cancer cell lines. Lapatinib also induced the accumulation of HER2 on the cell surface, resulting in the enhancement of trastuzumab-mediated ADCC of gastric cancer. CONCLUSIONS: Lapatinib exhibits inhibitory activity in gastric cancer cells, and the combination of lapatinib with trastuzumab may be a promising treatment strategy for gastric cancer patients. More... »
PAGES571-580
http://scigraph.springernature.com/pub.10.1007/s10120-012-0219-5
DOIhttp://dx.doi.org/10.1007/s10120-012-0219-5
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1026252759
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/23187882
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Oncology and Carcinogenesis",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Antibodies, Monoclonal, Humanized",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Antibody-Dependent Cell Cytotoxicity",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Antineoplastic Agents",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Apoptosis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Blotting, Western",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cell Proliferation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Drug Synergism",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Flow Cytometry",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Quinazolines",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Receptor, ErbB-2",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Stomach Neoplasms",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Trastuzumab",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Tumor Cells, Cultured",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "University of Yamanashi",
"id": "https://www.grid.ac/institutes/grid.267500.6",
"name": [
"First Department of Surgery, University of Yamanashi, Yamanashi, Japan"
],
"type": "Organization"
},
"familyName": "Shiraishi",
"givenName": "Kensuke",
"id": "sg:person.0752066310.31",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0752066310.31"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "National University of Singapore",
"id": "https://www.grid.ac/institutes/grid.4280.e",
"name": [
"Department of Surgery, National University of Singapore, Level 8, NUHS Tower Block, 1E Kent Ridge Road, 119228, Singapore, Singapore"
],
"type": "Organization"
},
"familyName": "Mimura",
"givenName": "Kousaku",
"id": "sg:person.01033220160.97",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033220160.97"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Yamanashi",
"id": "https://www.grid.ac/institutes/grid.267500.6",
"name": [
"First Department of Surgery, University of Yamanashi, Yamanashi, Japan"
],
"type": "Organization"
},
"familyName": "Izawa",
"givenName": "Shinichiro",
"id": "sg:person.0643306016.38",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643306016.38"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Yamanashi",
"id": "https://www.grid.ac/institutes/grid.267500.6",
"name": [
"First Department of Surgery, University of Yamanashi, Yamanashi, Japan"
],
"type": "Organization"
},
"familyName": "Inoue",
"givenName": "Ayako",
"id": "sg:person.0674336255.37",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674336255.37"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Yamanashi",
"id": "https://www.grid.ac/institutes/grid.267500.6",
"name": [
"First Department of Surgery, University of Yamanashi, Yamanashi, Japan"
],
"type": "Organization"
},
"familyName": "Shiba",
"givenName": "Shugo",
"id": "sg:person.01202725775.15",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202725775.15"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Yamanashi",
"id": "https://www.grid.ac/institutes/grid.267500.6",
"name": [
"First Department of Surgery, University of Yamanashi, Yamanashi, Japan"
],
"type": "Organization"
},
"familyName": "Maruyama",
"givenName": "Takanori",
"id": "sg:person.01020364175.10",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020364175.10"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Yamanashi",
"id": "https://www.grid.ac/institutes/grid.267500.6",
"name": [
"First Department of Surgery, University of Yamanashi, Yamanashi, Japan"
],
"type": "Organization"
},
"familyName": "Watanabe",
"givenName": "Mitsuaki",
"id": "sg:person.01251041175.54",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251041175.54"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Yamanashi",
"id": "https://www.grid.ac/institutes/grid.267500.6",
"name": [
"First Department of Surgery, University of Yamanashi, Yamanashi, Japan"
],
"type": "Organization"
},
"familyName": "Kawaguchi",
"givenName": "Yoshihiko",
"id": "sg:person.0636527335.66",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0636527335.66"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Yamanashi",
"id": "https://www.grid.ac/institutes/grid.267500.6",
"name": [
"First Department of Surgery, University of Yamanashi, Yamanashi, Japan"
],
"type": "Organization"
},
"familyName": "Inoue",
"givenName": "Masayuki",
"id": "sg:person.0626223055.63",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626223055.63"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Yamanashi",
"id": "https://www.grid.ac/institutes/grid.267500.6",
"name": [
"First Department of Surgery, University of Yamanashi, Yamanashi, Japan"
],
"type": "Organization"
},
"familyName": "Fujii",
"givenName": "Hideki",
"id": "sg:person.014173406752.52",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014173406752.52"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "National University of Singapore",
"id": "https://www.grid.ac/institutes/grid.4280.e",
"name": [
"Department of Surgery, National University of Singapore, Level 8, NUHS Tower Block, 1E Kent Ridge Road, 119228, Singapore, Singapore",
"Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore"
],
"type": "Organization"
},
"familyName": "Kono",
"givenName": "Koji",
"id": "sg:person.01362133435.33",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362133435.33"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1200/jco.2008.21.4437",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001671107"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1158/0008-5472.can-07-2068",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004264059"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmoa010187",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004811518"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1158/1078-0432.ccr-09-1112",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005686924"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00280-009-1215-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006829391",
"https://doi.org/10.1007/s00280-009-1215-2"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00280-009-1215-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006829391",
"https://doi.org/10.1007/s00280-009-1215-2"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature05474",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008085582",
"https://doi.org/10.1038/nature05474"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature05474",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008085582",
"https://doi.org/10.1038/nature05474"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ijc.25896",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008768260"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.4049/jimmunol.181.12.8382",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013822523"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmra043186",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015198110"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/onc.2008.432",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015615859",
"https://doi.org/10.1038/onc.2008.432"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.canlet.2011.03.002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016565509"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10120-011-0118-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018206312",
"https://doi.org/10.1007/s10120-011-0118-1"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmoa064320",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018697395"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2007.14.8957",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019255637"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrm1962",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020910010",
"https://doi.org/10.1038/nrm1962"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrm1962",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020910010",
"https://doi.org/10.1038/nrm1962"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2008.16.2578",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020998389"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1158/0008-5472.can-04-1168",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025987055"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2007.14.0590",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027551769"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/jso.22125",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027774740"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00000658-198807000-00005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028949246"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00000658-198807000-00005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028949246"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1158/0008-5472.can-05-1182",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030336226"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1245/s10434-011-1632-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030885217",
"https://doi.org/10.1245/s10434-011-1632-4"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.onc.1208774",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031051961",
"https://doi.org/10.1038/sj.onc.1208774"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.onc.1208774",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031051961",
"https://doi.org/10.1038/sj.onc.1208774"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.onc.1208774",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031051961",
"https://doi.org/10.1038/sj.onc.1208774"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ijc.10179",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033329756"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/mcb.16.10.5276",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034449776"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1158/1535-7163.mct-10-0209",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037331640"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1159/000226862",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037526328"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1517/14656566.8.13.2189",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037903060"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2007.13.9949",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043392679"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0140-6736(10)61121-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044182432"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/jcp.2006.038281",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044337705"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ijc.10257",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045202646"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1158/0008-5472.can-05-2506",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048950771"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/35052073",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053565592",
"https://doi.org/10.1038/35052073"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/35052073",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053565592",
"https://doi.org/10.1038/35052073"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/35052073",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053565592",
"https://doi.org/10.1038/35052073"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.1125951",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062453653"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.2470152",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062539373"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3892/ijo.2012.1485",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1071512814"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1074519294",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1075175865",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1075200120",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1078440580",
"type": "CreativeWork"
}
],
"datePublished": "2013-10",
"datePublishedReg": "2013-10-01",
"description": "BACKGROUND: Trastuzumab has been recently approved for clinical use to treat HER2-expressing advanced gastric cancer, and anti-HER2-targeting therapy has become a promising option for gastric cancer. Lapatinib is a dual tyrosine kinase inhibitor targeting EGFR and HER2. The aim of the present study was to explore the utility of lapatinib for gastric cancer, with a particular focus on trastuzumab-mediated antibody-dependent cellular cytotoxicity (ADCC).\nMETHODS: Nine gastric cancer cell lines were evaluated for the effects of lapatinib on the cell-surface accumulation of HER2 and analyzed for their additional effects on trastuzumab-mediated ADCC. Also, HER2 signaling with Western blot, proliferative function with the MTT assay, and apoptosis-inducing activity with 7ADD/Annexin-V were investigated when a panel of gastric cancer cell lines was treated with lapatinib.\nRESULTS: Lapatinib inhibited HER2 signaling and cell proliferation in the panel of gastric cancer cell lines. Lapatinib also induced the accumulation of HER2 on the cell surface, resulting in the enhancement of trastuzumab-mediated ADCC of gastric cancer.\nCONCLUSIONS: Lapatinib exhibits inhibitory activity in gastric cancer cells, and the combination of lapatinib with trastuzumab may be a promising treatment strategy for gastric cancer patients.",
"genre": "research_article",
"id": "sg:pub.10.1007/s10120-012-0219-5",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isFundedItemOf": [
{
"id": "sg:grant.6127891",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.6069937",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.6092974",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.6096642",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.6043483",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1020959",
"issn": [
"1436-3291",
"1436-3305"
],
"name": "Gastric Cancer",
"type": "Periodical"
},
{
"issueNumber": "4",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "16"
}
],
"name": "Lapatinib acts on gastric cancer through both antiproliferative function and augmentation of trastuzumab-mediated antibody-dependent cellular cytotoxicity",
"pagination": "571-580",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"7d10f785ee06e809225fd4e12856a414ed7cc33e4b01a818819a0917bb860732"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"23187882"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"100886238"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s10120-012-0219-5"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1026252759"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s10120-012-0219-5",
"https://app.dimensions.ai/details/publication/pub.1026252759"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T13:05",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8659_00000481.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007/s10120-012-0219-5"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10120-012-0219-5'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10120-012-0219-5'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10120-012-0219-5'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10120-012-0219-5'
This table displays all metadata directly associated to this object as RDF triples.
336 TRIPLES
21 PREDICATES
84 URIs
35 LITERALS
23 BLANK NODES