Use of the Ligase Detection Reaction-Polymerase Chain Reaction to Identify Point Mutations in Extended-Spectrum Beta-Lactamases View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-07

AUTHORS

C. Niederhauser, L. Kaempf, I. Heinzer

ABSTRACT

The aim of this study was to detect point mutations in extended-spectrum beta-lactamase (ESBL) genes in a background of wild-type (non-ESBL-producing) bacteria using a highly sensitive and specific method developed for this purpose. The ligase detection reaction-polymerase chain reaction (LDR-PCR) method was used to test different ESBL-producing strains and clinical isolates for a specific point mutation in the bla SHV-ESBL gene (glycine to serine mutation at position 238) and was compared with the commercially available E test ESBL (AB Biodisk, Sweden). Nine of the 40 clinical isolates tested were positive for the bla SHV-ESBL point mutation when tested by the LDR-PCR method but negative when tested by the E test. In contrast to the E test or other molecular genetic tests, the LDR-PCR method is able to identify a single bacterium with a point mutation in a background of 100,000 wild-type (non-ESBL-producing) bacteria. More... »

PAGES

477-480

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s100960000285

DOI

http://dx.doi.org/10.1007/s100960000285

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1015366990

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10947227


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Substitution", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Enterobacteriaceae", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Enterobacteriaceae Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes, Bacterial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ligase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Point Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "beta-Lactamases", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Kantonsspital Aarau", 
          "id": "https://www.grid.ac/institutes/grid.413357.7", 
          "name": [
            "Institute of Microbiology, Kantonsspital Aarau, 5001 Aarau, Switzerland e-mail: Christoph.Niederhauser@KSA.ch, CH"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Niederhauser", 
        "givenName": "C.", 
        "id": "sg:person.01321110261.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321110261.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kantonsspital Aarau", 
          "id": "https://www.grid.ac/institutes/grid.413357.7", 
          "name": [
            "Institute of Microbiology, Kantonsspital Aarau, 5001 Aarau, Switzerland e-mail: Christoph.Niederhauser@KSA.ch, CH"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kaempf", 
        "givenName": "L.", 
        "id": "sg:person.01333675700.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333675700.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kantonsspital Aarau", 
          "id": "https://www.grid.ac/institutes/grid.413357.7", 
          "name": [
            "Institute of Microbiology, Kantonsspital Aarau, 5001 Aarau, Switzerland e-mail: Christoph.Niederhauser@KSA.ch, CH"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Heinzer", 
        "givenName": "I.", 
        "id": "sg:person.0610271600.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610271600.55"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/0888-7543(89)90280-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004053545"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02390681", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007188860", 
          "https://doi.org/10.1007/bf02390681"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01641355", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010698546", 
          "https://doi.org/10.1007/bf01641355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01641355", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010698546", 
          "https://doi.org/10.1007/bf01641355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.28.2.302", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017299533"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.36.9.1877", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018038945"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01690097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023988744", 
          "https://doi.org/10.1007/bf01690097"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01690097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023988744", 
          "https://doi.org/10.1007/bf01690097"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01690097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023988744", 
          "https://doi.org/10.1007/bf01690097"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1469-0691.1997.tb00306.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030137002"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jac/38.3.409", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048334692"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2760269", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048919610"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2760269", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048919610"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.88.1.189", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050067650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01695658", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052599514", 
          "https://doi.org/10.1007/bf01695658"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01695658", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052599514", 
          "https://doi.org/10.1007/bf01695658"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01695658", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052599514", 
          "https://doi.org/10.1007/bf01695658"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/clinids/10.4.867", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059470550"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2000-07", 
    "datePublishedReg": "2000-07-01", 
    "description": "The aim of this study was to detect point mutations in extended-spectrum beta-lactamase (ESBL) genes in a background of wild-type (non-ESBL-producing) bacteria using a highly sensitive and specific method developed for this purpose. The ligase detection reaction-polymerase chain reaction (LDR-PCR) method was used to test different ESBL-producing strains and clinical isolates for a specific point mutation in the bla SHV-ESBL gene (glycine to serine mutation at position 238) and was compared with the commercially available E test ESBL (AB Biodisk, Sweden). Nine of the 40 clinical isolates tested were positive for the bla SHV-ESBL point mutation when tested by the LDR-PCR method but negative when tested by the E test. In contrast to the E test or other molecular genetic tests, the LDR-PCR method is able to identify a single bacterium with a point mutation in a background of 100,000 wild-type (non-ESBL-producing) bacteria.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s100960000285", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1093599", 
        "issn": [
          "0934-9723", 
          "1435-4373"
        ], 
        "name": "European Journal of Clinical Microbiology & Infectious Diseases", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "19"
      }
    ], 
    "name": "Use of the Ligase Detection Reaction-Polymerase Chain Reaction to Identify Point Mutations in Extended-Spectrum Beta-Lactamases", 
    "pagination": "477-480", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "4937cb8bd25f3b540f0fb708c9ca471f02496c47448e3279b3ee3cb1b1e223b1"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "10947227"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8804297"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s100960000285"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1015366990"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s100960000285", 
      "https://app.dimensions.ai/details/publication/pub.1015366990"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T18:14", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8675_00000487.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s100960000285"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s100960000285'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s100960000285'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s100960000285'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s100960000285'


 

This table displays all metadata directly associated to this object as RDF triples.

159 TRIPLES      21 PREDICATES      50 URIs      30 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s100960000285 schema:about N296cff00145040c1ad6223905fd63086
2 N3329d70e58924cef9b95477312594fe3
3 N45d409d057cb4a50ab9f2f4c48278f1b
4 N4c9c5192f8a844b390fe4aabbf5973ef
5 N58f94e301abb49e4888c644c7f84ac25
6 N7872147217224d45b0c752b725f4cab6
7 Ncba514ca4fcd41e68966ab54901de4d1
8 Ncc97fb13782446efa0a6853564dd2164
9 Nf91e286ed15143529d8bce628ca1c66e
10 anzsrc-for:06
11 anzsrc-for:0604
12 schema:author N71c9ee77bcee4bed97a08bd34db9e568
13 schema:citation sg:pub.10.1007/bf01641355
14 sg:pub.10.1007/bf01690097
15 sg:pub.10.1007/bf01695658
16 sg:pub.10.1007/bf02390681
17 https://doi.org/10.1016/0888-7543(89)90280-2
18 https://doi.org/10.1042/bj2760269
19 https://doi.org/10.1073/pnas.88.1.189
20 https://doi.org/10.1093/clinids/10.4.867
21 https://doi.org/10.1093/jac/38.3.409
22 https://doi.org/10.1111/j.1469-0691.1997.tb00306.x
23 https://doi.org/10.1128/aac.28.2.302
24 https://doi.org/10.1128/aac.36.9.1877
25 schema:datePublished 2000-07
26 schema:datePublishedReg 2000-07-01
27 schema:description The aim of this study was to detect point mutations in extended-spectrum beta-lactamase (ESBL) genes in a background of wild-type (non-ESBL-producing) bacteria using a highly sensitive and specific method developed for this purpose. The ligase detection reaction-polymerase chain reaction (LDR-PCR) method was used to test different ESBL-producing strains and clinical isolates for a specific point mutation in the bla SHV-ESBL gene (glycine to serine mutation at position 238) and was compared with the commercially available E test ESBL (AB Biodisk, Sweden). Nine of the 40 clinical isolates tested were positive for the bla SHV-ESBL point mutation when tested by the LDR-PCR method but negative when tested by the E test. In contrast to the E test or other molecular genetic tests, the LDR-PCR method is able to identify a single bacterium with a point mutation in a background of 100,000 wild-type (non-ESBL-producing) bacteria.
28 schema:genre research_article
29 schema:inLanguage en
30 schema:isAccessibleForFree false
31 schema:isPartOf N2fc73914ac0844698a22ba5283376467
32 Nd34f57d86120496a8f9acf479742f837
33 sg:journal.1093599
34 schema:name Use of the Ligase Detection Reaction-Polymerase Chain Reaction to Identify Point Mutations in Extended-Spectrum Beta-Lactamases
35 schema:pagination 477-480
36 schema:productId N43b8b56434264da6acc11ad41cae7071
37 N6c0eb56a62074e909983392516878d36
38 N73859063a14a4bfba5b54e45cbc5e194
39 Ncda8f15f2a644d8bb8551aa282364082
40 Ne963d979bc8748439ac91a9bc5e6a6d6
41 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015366990
42 https://doi.org/10.1007/s100960000285
43 schema:sdDatePublished 2019-04-10T18:14
44 schema:sdLicense https://scigraph.springernature.com/explorer/license/
45 schema:sdPublisher N48eb2df11c6c466880387652df3e4fab
46 schema:url http://link.springer.com/10.1007/s100960000285
47 sgo:license sg:explorer/license/
48 sgo:sdDataset articles
49 rdf:type schema:ScholarlyArticle
50 N296cff00145040c1ad6223905fd63086 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
51 schema:name Polymerase Chain Reaction
52 rdf:type schema:DefinedTerm
53 N2fc73914ac0844698a22ba5283376467 schema:issueNumber 6
54 rdf:type schema:PublicationIssue
55 N3329d70e58924cef9b95477312594fe3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
56 schema:name Humans
57 rdf:type schema:DefinedTerm
58 N43b8b56434264da6acc11ad41cae7071 schema:name doi
59 schema:value 10.1007/s100960000285
60 rdf:type schema:PropertyValue
61 N45d409d057cb4a50ab9f2f4c48278f1b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
62 schema:name Enterobacteriaceae Infections
63 rdf:type schema:DefinedTerm
64 N48eb2df11c6c466880387652df3e4fab schema:name Springer Nature - SN SciGraph project
65 rdf:type schema:Organization
66 N4c9c5192f8a844b390fe4aabbf5973ef schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
67 schema:name beta-Lactamases
68 rdf:type schema:DefinedTerm
69 N58f94e301abb49e4888c644c7f84ac25 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
70 schema:name Ligase Chain Reaction
71 rdf:type schema:DefinedTerm
72 N6c0eb56a62074e909983392516878d36 schema:name nlm_unique_id
73 schema:value 8804297
74 rdf:type schema:PropertyValue
75 N71c9ee77bcee4bed97a08bd34db9e568 rdf:first sg:person.01321110261.22
76 rdf:rest N73426ba1417847cfbf6ee434538235f9
77 N73426ba1417847cfbf6ee434538235f9 rdf:first sg:person.01333675700.06
78 rdf:rest Na04804a71fc541528ab6a2efc1b1f7b4
79 N73859063a14a4bfba5b54e45cbc5e194 schema:name readcube_id
80 schema:value 4937cb8bd25f3b540f0fb708c9ca471f02496c47448e3279b3ee3cb1b1e223b1
81 rdf:type schema:PropertyValue
82 N7872147217224d45b0c752b725f4cab6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Enterobacteriaceae
84 rdf:type schema:DefinedTerm
85 Na04804a71fc541528ab6a2efc1b1f7b4 rdf:first sg:person.0610271600.55
86 rdf:rest rdf:nil
87 Ncba514ca4fcd41e68966ab54901de4d1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Genes, Bacterial
89 rdf:type schema:DefinedTerm
90 Ncc97fb13782446efa0a6853564dd2164 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Point Mutation
92 rdf:type schema:DefinedTerm
93 Ncda8f15f2a644d8bb8551aa282364082 schema:name pubmed_id
94 schema:value 10947227
95 rdf:type schema:PropertyValue
96 Nd34f57d86120496a8f9acf479742f837 schema:volumeNumber 19
97 rdf:type schema:PublicationVolume
98 Ne963d979bc8748439ac91a9bc5e6a6d6 schema:name dimensions_id
99 schema:value pub.1015366990
100 rdf:type schema:PropertyValue
101 Nf91e286ed15143529d8bce628ca1c66e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Amino Acid Substitution
103 rdf:type schema:DefinedTerm
104 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
105 schema:name Biological Sciences
106 rdf:type schema:DefinedTerm
107 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
108 schema:name Genetics
109 rdf:type schema:DefinedTerm
110 sg:journal.1093599 schema:issn 0934-9723
111 1435-4373
112 schema:name European Journal of Clinical Microbiology & Infectious Diseases
113 rdf:type schema:Periodical
114 sg:person.01321110261.22 schema:affiliation https://www.grid.ac/institutes/grid.413357.7
115 schema:familyName Niederhauser
116 schema:givenName C.
117 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321110261.22
118 rdf:type schema:Person
119 sg:person.01333675700.06 schema:affiliation https://www.grid.ac/institutes/grid.413357.7
120 schema:familyName Kaempf
121 schema:givenName L.
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333675700.06
123 rdf:type schema:Person
124 sg:person.0610271600.55 schema:affiliation https://www.grid.ac/institutes/grid.413357.7
125 schema:familyName Heinzer
126 schema:givenName I.
127 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610271600.55
128 rdf:type schema:Person
129 sg:pub.10.1007/bf01641355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010698546
130 https://doi.org/10.1007/bf01641355
131 rdf:type schema:CreativeWork
132 sg:pub.10.1007/bf01690097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023988744
133 https://doi.org/10.1007/bf01690097
134 rdf:type schema:CreativeWork
135 sg:pub.10.1007/bf01695658 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052599514
136 https://doi.org/10.1007/bf01695658
137 rdf:type schema:CreativeWork
138 sg:pub.10.1007/bf02390681 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007188860
139 https://doi.org/10.1007/bf02390681
140 rdf:type schema:CreativeWork
141 https://doi.org/10.1016/0888-7543(89)90280-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004053545
142 rdf:type schema:CreativeWork
143 https://doi.org/10.1042/bj2760269 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048919610
144 rdf:type schema:CreativeWork
145 https://doi.org/10.1073/pnas.88.1.189 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050067650
146 rdf:type schema:CreativeWork
147 https://doi.org/10.1093/clinids/10.4.867 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059470550
148 rdf:type schema:CreativeWork
149 https://doi.org/10.1093/jac/38.3.409 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048334692
150 rdf:type schema:CreativeWork
151 https://doi.org/10.1111/j.1469-0691.1997.tb00306.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1030137002
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1128/aac.28.2.302 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017299533
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1128/aac.36.9.1877 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018038945
156 rdf:type schema:CreativeWork
157 https://www.grid.ac/institutes/grid.413357.7 schema:alternateName Kantonsspital Aarau
158 schema:name Institute of Microbiology, Kantonsspital Aarau, 5001 Aarau, Switzerland e-mail: Christoph.Niederhauser@KSA.ch, CH
159 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...