Ontology type: schema:ScholarlyArticle
2018-09
AUTHORSHeidi C. Smith-Vaughan, Michael J. Binks, Jemima Beissbarth, Anne B. Chang, Gabrielle B. McCallum, Ian M. Mackay, Peter S. Morris, Robyn L. Marsh, Paul J. Torzillo, Danielle F. Wurzel, Keith Grimwood, Elizabeth Nosworthy, Jane E. Gaydon, Amanda J. Leach, Barbara MacHunter, Mark D. Chatfield, Theo P. Sloots, Allen C. Cheng
ABSTRACTAcute lower respiratory infection (ALRI) is a major cause of hospitalization for Indigenous children in remote regions of Australia. The associated microbiology remains unclear. Our aim was to determine whether the microbes present in the nasopharynx before an ALRI were associated with its onset. A retrospective case-control/crossover study among Indigenous children aged up to 2 years. ALRI cases identified by medical note review were eligible where nasopharyngeal swabs were available: (1) 0-21 days before ALRI onset (case); (2) 90-180 days before ALRI onset (same child controls); and (3) from time and age-matched children without ALRI (different child controls). PCR assays determined the presence and/or load of selected respiratory pathogens. Among 104 children (182 recorded ALRI episodes), 120 case-same child control and 170 case-different child control swab pairs were identified. Human adenoviruses (HAdV) were more prevalent in cases compared to same child controls (18 vs 7%; OR = 3.08, 95% CI 1.22-7.76, p = 0.017), but this association was not significant in cases versus different child controls (15 vs 10%; OR = 1.93, 95% CI 0.97-3.87 (p = 0.063). No other microbes were more prevalent in cases compared to controls. Streptococcus pneumoniae (74%), Haemophilus influenzae (75%) and Moraxella catarrhalis (88%) were commonly identified across all swabs. In a pediatric population with a high detection rate of nasopharyngeal microbes, HAdV was the only pathogen detected in the period before illness presentation that was significantly associated with ALRI onset. Detection of other potential ALRI pathogens was similar between cases and controls. More... »
PAGES1785-1794
http://scigraph.springernature.com/pub.10.1007/s10096-018-3314-7
DOIhttp://dx.doi.org/10.1007/s10096-018-3314-7
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1105217251
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/29959609
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]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10096-018-3314-7'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10096-018-3314-7'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10096-018-3314-7'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10096-018-3314-7'
This table displays all metadata directly associated to this object as RDF triples.
334 TRIPLES
21 PREDICATES
61 URIs
21 LITERALS
9 BLANK NODES