Mycobacterial infections in adult patients with hematological malignancy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-06

AUTHORS

C.-Y. Chen, W.-H. Sheng, C.-C. Lai, C.-H. Liao, Y.-T. Huang, W. Tsay, S.-Y. Huang, J.-L. Tang, H.-F. Tien, P.-R. Hsueh

ABSTRACT

We retrospectively analyzed the clinical and microbiological characteristics of adult patients with hematological malignancy and nontuberculous mycobacteria (NTM) infections from 2001 to 2010. During the study period, 50 patients with hematological malignancy and tuberculosis (TB) were also evaluated. Among 2,846 patients with hematological malignancy, 34 (1.2%) patients had NTM infections. Mycobacterium avium-intracellulare complex (13 patients, 38%) was the most commonly isolated species, followed by M. abscessus (21%), M. fortuitum (18%), and M. kansasii (18%). Twenty-six patients had pulmonary NTM infection and eight patients had disseminated disease. Neutropenia was more frequently encountered among patients with disseminated NTM disease (p = 0.007) at diagnosis than among patients with pulmonary disease only. Twenty-five (74%) patients received adequate initial antibiotic treatment. Five of the 34 patients died within 30 days after diagnosis. Cox regression multivariate analysis showed that chronic kidney disease (p = 0.017) and neutropenia at diagnosis (p = 0.032) were independent prognostic factors of NTM infection in patients with hematological malignancy. Patients with NTM infection had higher absolute neutrophil counts at diagnosis (p = 0.003) and a higher 30-day mortality rate (15% vs. 2%, p = 0.025) than TB patients. Hematological patients with chronic kidney disease and febrile neutropenia who developed NTM infection had significant worse prognosis than patients with TB infection. More... »

PAGES

1059-1066

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10096-011-1407-7

DOI

http://dx.doi.org/10.1007/s10096-011-1407-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1039183866

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21901631


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Bacterial Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bacteremia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hematologic Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mycobacterium Infections, Nontuberculous", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neutropenia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nontuberculous Mycobacteria", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pneumonia, Bacterial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "National Taiwan University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412094.a", 
          "name": [
            "Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chen", 
        "givenName": "C.-Y.", 
        "id": "sg:person.01175525743.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175525743.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Taiwan University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412094.a", 
          "name": [
            "Division of Infectious Disease, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sheng", 
        "givenName": "W.-H.", 
        "id": "sg:person.0741471242.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741471242.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chi Mei Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.413876.f", 
          "name": [
            "Department of Intensive Care Medicine, Chi-Mei Medical Center, Tainan, Liouying, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lai", 
        "givenName": "C.-C.", 
        "id": "sg:person.01215367521.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215367521.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Far Eastern Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.414746.4", 
          "name": [
            "Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Liao", 
        "givenName": "C.-H.", 
        "id": "sg:person.01144165703.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01144165703.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Far Eastern Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.414746.4", 
          "name": [
            "Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Huang", 
        "givenName": "Y.-T.", 
        "id": "sg:person.0601061567.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601061567.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Taiwan University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412094.a", 
          "name": [
            "Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tsay", 
        "givenName": "W.", 
        "id": "sg:person.0721210172.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721210172.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Taiwan University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412094.a", 
          "name": [
            "Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Huang", 
        "givenName": "S.-Y.", 
        "id": "sg:person.016600345354.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016600345354.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Taiwan University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412094.a", 
          "name": [
            "Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tang", 
        "givenName": "J.-L.", 
        "id": "sg:person.011336406464.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011336406464.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Taiwan University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412094.a", 
          "name": [
            "Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tien", 
        "givenName": "H.-F.", 
        "id": "sg:person.013177614042.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013177614042.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Taiwan University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412094.a", 
          "name": [
            "Division of Infectious Disease, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan", 
            "Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hsueh", 
        "givenName": "P.-R.", 
        "id": "sg:person.0713663251.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713663251.48"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1183/09031936.00140007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006118671"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/420746", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009522589"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1704043", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011041081", 
          "https://doi.org/10.1038/sj.bmt.1704043"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10096-009-0789-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011556286", 
          "https://doi.org/10.1007/s10096-009-0789-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10096-009-0789-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011556286", 
          "https://doi.org/10.1007/s10096-009-0789-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10096-009-0789-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011556286", 
          "https://doi.org/10.1007/s10096-009-0789-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.200604-571st", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017257548"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/rlu.0b013e3181662fb2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020781418"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/thx.2006.070797", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023237341"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/thx.2006.070797", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023237341"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1704210", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026353097", 
          "https://doi.org/10.1038/sj.bmt.1704210"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.diagmicrobio.2010.05.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028289034"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.200702-201oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030194178"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s15010-004-4001-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038717764", 
          "https://doi.org/10.1007/s15010-004-4001-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00043426-200210000-00013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041032294"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00043426-200210000-00013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041032294"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/514981", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047038862"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/eid1602.090675", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049802472"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.idc.2010.04.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051530765"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0046-8177(82)80084-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052532096"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/003655400459586", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053481834"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s0950268809991208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053826954"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/eid170310060", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071123139"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076795344", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076880631", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1043/1543-2165(2008)132[1333:nmi]2.0.co;2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077685852"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/eid1703.100604", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078362525"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2012-06", 
    "datePublishedReg": "2012-06-01", 
    "description": "We retrospectively analyzed the clinical and microbiological characteristics of adult patients with hematological malignancy and nontuberculous mycobacteria (NTM) infections from 2001 to 2010. During the study period, 50 patients with hematological malignancy and tuberculosis (TB) were also evaluated. Among 2,846 patients with hematological malignancy, 34 (1.2%) patients had NTM infections. Mycobacterium avium-intracellulare complex (13 patients, 38%) was the most commonly isolated species, followed by M. abscessus (21%), M. fortuitum (18%), and M. kansasii (18%). Twenty-six patients had pulmonary NTM infection and eight patients had disseminated disease. Neutropenia was more frequently encountered among patients with disseminated NTM disease (p = 0.007) at diagnosis than among patients with pulmonary disease only. Twenty-five (74%) patients received adequate initial antibiotic treatment. Five of the 34 patients died within 30 days after diagnosis. Cox regression multivariate analysis showed that chronic kidney disease (p = 0.017) and neutropenia at diagnosis (p = 0.032) were independent prognostic factors of NTM infection in patients with hematological malignancy. Patients with NTM infection had higher absolute neutrophil counts at diagnosis (p = 0.003) and a higher 30-day mortality rate (15% vs. 2%, p = 0.025) than TB patients. Hematological patients with chronic kidney disease and febrile neutropenia who developed NTM infection had significant worse prognosis than patients with TB infection.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s10096-011-1407-7", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1093599", 
        "issn": [
          "0934-9723", 
          "1435-4373"
        ], 
        "name": "European Journal of Clinical Microbiology & Infectious Diseases", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "31"
      }
    ], 
    "name": "Mycobacterial infections in adult patients with hematological malignancy", 
    "pagination": "1059-1066", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "baa6d726b8d594ab097de2a63676418a53cf8bb521b78d2523653df555fb66d4"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "21901631"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8804297"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s10096-011-1407-7"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1039183866"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s10096-011-1407-7", 
      "https://app.dimensions.ai/details/publication/pub.1039183866"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T10:39", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000349_0000000349/records_113679_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs10096-011-1407-7"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10096-011-1407-7'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10096-011-1407-7'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10096-011-1407-7'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10096-011-1407-7'


 

This table displays all metadata directly associated to this object as RDF triples.

283 TRIPLES      21 PREDICATES      70 URIs      39 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s10096-011-1407-7 schema:about N019429292b954fc7b7b372a7cefebd10
2 N0c0b367a46c2467f9e1d28407fda96f1
3 N10855c0f73174939b64b4756295f3cd1
4 N11d49a13f95a46669748b7fb4d98690e
5 N1f4c7e3b5b1147938cbdfb782b20dda8
6 N2f97bccc60a14ce5a7c5f38752dd0d99
7 N32a51d4110544e278b2b703c097d4f3e
8 N36f6bc61ac694f3db09cea4561e82740
9 N45a045207dfa4274bd4f4ae2b50966e6
10 N4d425afd05e14232908f457a8966902f
11 N5fa70b2b3e45452193e6aaa97cc59c04
12 N69d40c67ec0645f7a53fa9b2b913d6c1
13 N6f188897b634483d8fcd7df8aceda8e4
14 N7b65c4fff4074d5a9f99c098b292d3c0
15 N89800a8116a94421a3ad3ffe0b76f384
16 N9c045d68f4d8455ea507ae3793ee252d
17 Nf5f6dfa6144d411c9697d9585ba752b0
18 Nfdfa2ffd4eea4854987bc15f7e9d76a6
19 anzsrc-for:11
20 anzsrc-for:1103
21 schema:author Nd85e30519ebd41aa91387663ea72a408
22 schema:citation sg:pub.10.1007/s10096-009-0789-2
23 sg:pub.10.1007/s15010-004-4001-4
24 sg:pub.10.1038/sj.bmt.1704043
25 sg:pub.10.1038/sj.bmt.1704210
26 https://app.dimensions.ai/details/publication/pub.1076795344
27 https://app.dimensions.ai/details/publication/pub.1076880631
28 https://doi.org/10.1016/j.diagmicrobio.2010.05.017
29 https://doi.org/10.1016/j.idc.2010.04.008
30 https://doi.org/10.1016/s0046-8177(82)80084-1
31 https://doi.org/10.1017/s0950268809991208
32 https://doi.org/10.1043/1543-2165(2008)132[1333:nmi]2.0.co;2
33 https://doi.org/10.1080/003655400459586
34 https://doi.org/10.1086/420746
35 https://doi.org/10.1086/514981
36 https://doi.org/10.1097/00043426-200210000-00013
37 https://doi.org/10.1097/rlu.0b013e3181662fb2
38 https://doi.org/10.1136/thx.2006.070797
39 https://doi.org/10.1164/rccm.200604-571st
40 https://doi.org/10.1164/rccm.200702-201oc
41 https://doi.org/10.1183/09031936.00140007
42 https://doi.org/10.3201/eid1602.090675
43 https://doi.org/10.3201/eid1703.100604
44 https://doi.org/10.3201/eid170310060
45 schema:datePublished 2012-06
46 schema:datePublishedReg 2012-06-01
47 schema:description We retrospectively analyzed the clinical and microbiological characteristics of adult patients with hematological malignancy and nontuberculous mycobacteria (NTM) infections from 2001 to 2010. During the study period, 50 patients with hematological malignancy and tuberculosis (TB) were also evaluated. Among 2,846 patients with hematological malignancy, 34 (1.2%) patients had NTM infections. Mycobacterium avium-intracellulare complex (13 patients, 38%) was the most commonly isolated species, followed by M. abscessus (21%), M. fortuitum (18%), and M. kansasii (18%). Twenty-six patients had pulmonary NTM infection and eight patients had disseminated disease. Neutropenia was more frequently encountered among patients with disseminated NTM disease (p = 0.007) at diagnosis than among patients with pulmonary disease only. Twenty-five (74%) patients received adequate initial antibiotic treatment. Five of the 34 patients died within 30 days after diagnosis. Cox regression multivariate analysis showed that chronic kidney disease (p = 0.017) and neutropenia at diagnosis (p = 0.032) were independent prognostic factors of NTM infection in patients with hematological malignancy. Patients with NTM infection had higher absolute neutrophil counts at diagnosis (p = 0.003) and a higher 30-day mortality rate (15% vs. 2%, p = 0.025) than TB patients. Hematological patients with chronic kidney disease and febrile neutropenia who developed NTM infection had significant worse prognosis than patients with TB infection.
48 schema:genre research_article
49 schema:inLanguage en
50 schema:isAccessibleForFree false
51 schema:isPartOf N6be8810ff4df46109c02c0d20ec6bc0e
52 Nce5c7192575c47a296f8715c5ead7dd8
53 sg:journal.1093599
54 schema:name Mycobacterial infections in adult patients with hematological malignancy
55 schema:pagination 1059-1066
56 schema:productId N5ff86993d0e74e00b9e2bbba159b4ff5
57 N60c268ca5612448dbfc9dd36c51862eb
58 N720d8dc895294f46aaef5aff17aa4342
59 N7d3df0a1f31044b9a37dccb2626ac805
60 Nbd5fed69f2e74d6aa5274588db890662
61 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039183866
62 https://doi.org/10.1007/s10096-011-1407-7
63 schema:sdDatePublished 2019-04-11T10:39
64 schema:sdLicense https://scigraph.springernature.com/explorer/license/
65 schema:sdPublisher Nf87360cbe37a44169bf6ea85f7192af3
66 schema:url https://link.springer.com/10.1007%2Fs10096-011-1407-7
67 sgo:license sg:explorer/license/
68 sgo:sdDataset articles
69 rdf:type schema:ScholarlyArticle
70 N019429292b954fc7b7b372a7cefebd10 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
71 schema:name Humans
72 rdf:type schema:DefinedTerm
73 N05c8b38bf38942dbae110e8e0f9ce814 rdf:first sg:person.01144165703.61
74 rdf:rest N7af2d9400dca4e398ce4f6053221d0a1
75 N0c0b367a46c2467f9e1d28407fda96f1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Female
77 rdf:type schema:DefinedTerm
78 N10855c0f73174939b64b4756295f3cd1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Adult
80 rdf:type schema:DefinedTerm
81 N10e26dc3d9a245399c8888e37b2f8035 rdf:first sg:person.01215367521.48
82 rdf:rest N05c8b38bf38942dbae110e8e0f9ce814
83 N11d49a13f95a46669748b7fb4d98690e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Aged
85 rdf:type schema:DefinedTerm
86 N14ab5d869ec24d148125178c7b84b114 rdf:first sg:person.0721210172.02
87 rdf:rest N77dfc6f2a1354b5e998cc917b6ea7da1
88 N14c9ffad2d1b4a7882de5aa08e1cd1f3 rdf:first sg:person.013177614042.37
89 rdf:rest Na62acb4cd42a44e79883cda71dfa55cd
90 N1f4c7e3b5b1147938cbdfb782b20dda8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Aged, 80 and over
92 rdf:type schema:DefinedTerm
93 N2f97bccc60a14ce5a7c5f38752dd0d99 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Anti-Bacterial Agents
95 rdf:type schema:DefinedTerm
96 N32a51d4110544e278b2b703c097d4f3e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Male
98 rdf:type schema:DefinedTerm
99 N36f6bc61ac694f3db09cea4561e82740 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Retrospective Studies
101 rdf:type schema:DefinedTerm
102 N45a045207dfa4274bd4f4ae2b50966e6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Adolescent
104 rdf:type schema:DefinedTerm
105 N46e04166032748088e16a859e19c03b8 rdf:first sg:person.011336406464.70
106 rdf:rest N14c9ffad2d1b4a7882de5aa08e1cd1f3
107 N4d425afd05e14232908f457a8966902f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Mycobacterium Infections, Nontuberculous
109 rdf:type schema:DefinedTerm
110 N5fa70b2b3e45452193e6aaa97cc59c04 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Survival Analysis
112 rdf:type schema:DefinedTerm
113 N5ff86993d0e74e00b9e2bbba159b4ff5 schema:name doi
114 schema:value 10.1007/s10096-011-1407-7
115 rdf:type schema:PropertyValue
116 N60c268ca5612448dbfc9dd36c51862eb schema:name pubmed_id
117 schema:value 21901631
118 rdf:type schema:PropertyValue
119 N69d40c67ec0645f7a53fa9b2b913d6c1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Young Adult
121 rdf:type schema:DefinedTerm
122 N6be8810ff4df46109c02c0d20ec6bc0e schema:volumeNumber 31
123 rdf:type schema:PublicationVolume
124 N6f188897b634483d8fcd7df8aceda8e4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Pneumonia, Bacterial
126 rdf:type schema:DefinedTerm
127 N720d8dc895294f46aaef5aff17aa4342 schema:name readcube_id
128 schema:value baa6d726b8d594ab097de2a63676418a53cf8bb521b78d2523653df555fb66d4
129 rdf:type schema:PropertyValue
130 N77dfc6f2a1354b5e998cc917b6ea7da1 rdf:first sg:person.016600345354.31
131 rdf:rest N46e04166032748088e16a859e19c03b8
132 N7af2d9400dca4e398ce4f6053221d0a1 rdf:first sg:person.0601061567.74
133 rdf:rest N14ab5d869ec24d148125178c7b84b114
134 N7b65c4fff4074d5a9f99c098b292d3c0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Nontuberculous Mycobacteria
136 rdf:type schema:DefinedTerm
137 N7d3df0a1f31044b9a37dccb2626ac805 schema:name nlm_unique_id
138 schema:value 8804297
139 rdf:type schema:PropertyValue
140 N89800a8116a94421a3ad3ffe0b76f384 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Neutropenia
142 rdf:type schema:DefinedTerm
143 N9c045d68f4d8455ea507ae3793ee252d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Middle Aged
145 rdf:type schema:DefinedTerm
146 Na62acb4cd42a44e79883cda71dfa55cd rdf:first sg:person.0713663251.48
147 rdf:rest rdf:nil
148 Nbd5fed69f2e74d6aa5274588db890662 schema:name dimensions_id
149 schema:value pub.1039183866
150 rdf:type schema:PropertyValue
151 Nc28de6290dca451484ecc1717b223c34 rdf:first sg:person.0741471242.58
152 rdf:rest N10e26dc3d9a245399c8888e37b2f8035
153 Nce5c7192575c47a296f8715c5ead7dd8 schema:issueNumber 6
154 rdf:type schema:PublicationIssue
155 Nd85e30519ebd41aa91387663ea72a408 rdf:first sg:person.01175525743.45
156 rdf:rest Nc28de6290dca451484ecc1717b223c34
157 Nf5f6dfa6144d411c9697d9585ba752b0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Hematologic Neoplasms
159 rdf:type schema:DefinedTerm
160 Nf87360cbe37a44169bf6ea85f7192af3 schema:name Springer Nature - SN SciGraph project
161 rdf:type schema:Organization
162 Nfdfa2ffd4eea4854987bc15f7e9d76a6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Bacteremia
164 rdf:type schema:DefinedTerm
165 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
166 schema:name Medical and Health Sciences
167 rdf:type schema:DefinedTerm
168 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
169 schema:name Clinical Sciences
170 rdf:type schema:DefinedTerm
171 sg:journal.1093599 schema:issn 0934-9723
172 1435-4373
173 schema:name European Journal of Clinical Microbiology & Infectious Diseases
174 rdf:type schema:Periodical
175 sg:person.011336406464.70 schema:affiliation https://www.grid.ac/institutes/grid.412094.a
176 schema:familyName Tang
177 schema:givenName J.-L.
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011336406464.70
179 rdf:type schema:Person
180 sg:person.01144165703.61 schema:affiliation https://www.grid.ac/institutes/grid.414746.4
181 schema:familyName Liao
182 schema:givenName C.-H.
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01144165703.61
184 rdf:type schema:Person
185 sg:person.01175525743.45 schema:affiliation https://www.grid.ac/institutes/grid.412094.a
186 schema:familyName Chen
187 schema:givenName C.-Y.
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175525743.45
189 rdf:type schema:Person
190 sg:person.01215367521.48 schema:affiliation https://www.grid.ac/institutes/grid.413876.f
191 schema:familyName Lai
192 schema:givenName C.-C.
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215367521.48
194 rdf:type schema:Person
195 sg:person.013177614042.37 schema:affiliation https://www.grid.ac/institutes/grid.412094.a
196 schema:familyName Tien
197 schema:givenName H.-F.
198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013177614042.37
199 rdf:type schema:Person
200 sg:person.016600345354.31 schema:affiliation https://www.grid.ac/institutes/grid.412094.a
201 schema:familyName Huang
202 schema:givenName S.-Y.
203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016600345354.31
204 rdf:type schema:Person
205 sg:person.0601061567.74 schema:affiliation https://www.grid.ac/institutes/grid.414746.4
206 schema:familyName Huang
207 schema:givenName Y.-T.
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601061567.74
209 rdf:type schema:Person
210 sg:person.0713663251.48 schema:affiliation https://www.grid.ac/institutes/grid.412094.a
211 schema:familyName Hsueh
212 schema:givenName P.-R.
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713663251.48
214 rdf:type schema:Person
215 sg:person.0721210172.02 schema:affiliation https://www.grid.ac/institutes/grid.412094.a
216 schema:familyName Tsay
217 schema:givenName W.
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721210172.02
219 rdf:type schema:Person
220 sg:person.0741471242.58 schema:affiliation https://www.grid.ac/institutes/grid.412094.a
221 schema:familyName Sheng
222 schema:givenName W.-H.
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741471242.58
224 rdf:type schema:Person
225 sg:pub.10.1007/s10096-009-0789-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011556286
226 https://doi.org/10.1007/s10096-009-0789-2
227 rdf:type schema:CreativeWork
228 sg:pub.10.1007/s15010-004-4001-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038717764
229 https://doi.org/10.1007/s15010-004-4001-4
230 rdf:type schema:CreativeWork
231 sg:pub.10.1038/sj.bmt.1704043 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011041081
232 https://doi.org/10.1038/sj.bmt.1704043
233 rdf:type schema:CreativeWork
234 sg:pub.10.1038/sj.bmt.1704210 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026353097
235 https://doi.org/10.1038/sj.bmt.1704210
236 rdf:type schema:CreativeWork
237 https://app.dimensions.ai/details/publication/pub.1076795344 schema:CreativeWork
238 https://app.dimensions.ai/details/publication/pub.1076880631 schema:CreativeWork
239 https://doi.org/10.1016/j.diagmicrobio.2010.05.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028289034
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1016/j.idc.2010.04.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051530765
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1016/s0046-8177(82)80084-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052532096
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1017/s0950268809991208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053826954
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1043/1543-2165(2008)132[1333:nmi]2.0.co;2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077685852
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1080/003655400459586 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053481834
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1086/420746 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009522589
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1086/514981 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047038862
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1097/00043426-200210000-00013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041032294
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1097/rlu.0b013e3181662fb2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020781418
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1136/thx.2006.070797 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023237341
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1164/rccm.200604-571st schema:sameAs https://app.dimensions.ai/details/publication/pub.1017257548
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1164/rccm.200702-201oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1030194178
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1183/09031936.00140007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006118671
266 rdf:type schema:CreativeWork
267 https://doi.org/10.3201/eid1602.090675 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049802472
268 rdf:type schema:CreativeWork
269 https://doi.org/10.3201/eid1703.100604 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078362525
270 rdf:type schema:CreativeWork
271 https://doi.org/10.3201/eid170310060 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071123139
272 rdf:type schema:CreativeWork
273 https://www.grid.ac/institutes/grid.412094.a schema:alternateName National Taiwan University Hospital
274 schema:name Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan
275 Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
276 Division of Infectious Disease, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
277 rdf:type schema:Organization
278 https://www.grid.ac/institutes/grid.413876.f schema:alternateName Chi Mei Medical Center
279 schema:name Department of Intensive Care Medicine, Chi-Mei Medical Center, Tainan, Liouying, Taiwan
280 rdf:type schema:Organization
281 https://www.grid.ac/institutes/grid.414746.4 schema:alternateName Far Eastern Memorial Hospital
282 schema:name Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan
283 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...