Ontology type: schema:ScholarlyArticle
2021-03-16
AUTHORSLaura Carelli, Federica Solca, Simone Migliore, Silvia Torre, Agostino Brugnera, Francesca Mancini, Sofia Tagini, Roberta Ferrucci, Sabrina Maffi, Consuelo Ceccarelli, Jacopo Pasquini, Jenny Sassone, Ferdinando Squitieri, Andrea Ciammola, Vincenzo Silani, Barbara Poletti
ABSTRACTIntroductionThe study aims at investigating psychometric properties of the Edinburgh cognitive and behavioural ALS screen (ECAS) in Parkinson’s (PD) and Huntington’s (HD) diseases. The sensitivity and specificity of the ECAS in highlighting HD and PD cognitive-behavioural features and in differentiating between these two populations and from healthy controls (HC) were evaluated. Moreover, correlations between the ECAS and traditional cognitive measures, together with core clinical features, were analysed.MethodsSeventy-three PD patients, 38 HD patients, and 49 education-matched healthy participants were enrolled. Participants were administered the ECAS, together with other cognitive screening tools and psychological questionnaires. Patients’ behavioural assessment was also carried out with carers.ResultsThe ECAS distinguished between HD patients and HC and between the two clinical syndromes with high sensitivity and specificity. Even if the diagnostic accuracy of the ECAS in distinguishing between PD and HC was low, the PD cognitive phenotype was very well described by the ECAS performances. Convergent validity of the ECAS against other traditional cognitive screening was observed, as well as correlations with psychological aspects and typical clinical features, especially for the HD group.ConclusionsThe ECAS represents a rapid and feasible tool, useful also in other neurodegenerative disorders affecting verbal-motor abilities than the amyotrophic lateral sclerosis such as PD and HD. Clinical applications in these neurodegenerative conditions require further investigations and, probably, some adaptations of the original test. More... »
PAGES4997-5006
http://scigraph.springernature.com/pub.10.1007/s10072-021-05169-3
DOIhttp://dx.doi.org/10.1007/s10072-021-05169-3
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1136444861
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/33728549
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Neurosciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.418224.9",
"name": [
"Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy"
],
"type": "Organization"
},
"familyName": "Carelli",
"givenName": "Laura",
"id": "sg:person.0600423357.05",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600423357.05"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Pathophysiology and Transplantation, \u201cDino Ferrari\u201d Center, University of Milan, Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.4708.b",
"name": [
"Department of Pathophysiology and Transplantation, \u201cDino Ferrari\u201d Center, University of Milan, Milan, Italy"
],
"type": "Organization"
},
"familyName": "Solca",
"givenName": "Federica",
"id": "sg:person.01367722454.64",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367722454.64"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Huntington and Rare Diseases Unit, Fondazione IRCCS Casa Sollievo Della Sofferenza Research Hospital, San Giovanni Rotondo, Italy",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Huntington and Rare Diseases Unit, Fondazione IRCCS Casa Sollievo Della Sofferenza Research Hospital, San Giovanni Rotondo, Italy"
],
"type": "Organization"
},
"familyName": "Migliore",
"givenName": "Simone",
"id": "sg:person.01363323121.85",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01363323121.85"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.418224.9",
"name": [
"Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy"
],
"type": "Organization"
},
"familyName": "Torre",
"givenName": "Silvia",
"id": "sg:person.016016247513.44",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016016247513.44"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Human and Social Sciences, University of Bergamo, Bergamo, Italy",
"id": "http://www.grid.ac/institutes/grid.33236.37",
"name": [
"Department of Human and Social Sciences, University of Bergamo, Bergamo, Italy"
],
"type": "Organization"
},
"familyName": "Brugnera",
"givenName": "Agostino",
"id": "sg:person.011204335441.13",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011204335441.13"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.418224.9",
"name": [
"Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy"
],
"type": "Organization"
},
"familyName": "Mancini",
"givenName": "Francesca",
"id": "sg:person.0635556432.18",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635556432.18"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.418224.9",
"name": [
"Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy"
],
"type": "Organization"
},
"familyName": "Tagini",
"givenName": "Sofia",
"id": "sg:person.012576003603.58",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012576003603.58"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "IRCCS Ca\u2019 Granda Foundation Maggiore Policlinico Hospital, Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.414818.0",
"name": [
"Aldo Ravelli Center for Neurotechnology and Experimental Brain Therapeutics, Department of Health Sciences, International Medical School, University of Milan, Milan, Italy",
"ASST Santi Paolo e Carlo, Neurology Clinic III, Milan, Italy",
"IRCCS Ca\u2019 Granda Foundation Maggiore Policlinico Hospital, Milan, Italy"
],
"type": "Organization"
},
"familyName": "Ferrucci",
"givenName": "Roberta",
"id": "sg:person.01005070065.19",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01005070065.19"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Huntington and Rare Diseases Unit, Fondazione IRCCS Casa Sollievo Della Sofferenza Research Hospital, San Giovanni Rotondo, Italy",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Huntington and Rare Diseases Unit, Fondazione IRCCS Casa Sollievo Della Sofferenza Research Hospital, San Giovanni Rotondo, Italy"
],
"type": "Organization"
},
"familyName": "Maffi",
"givenName": "Sabrina",
"id": "sg:person.010271373601.31",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010271373601.31"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Italian League for Research on Huntington Disease (LIRH) Foundation, Rome, Italy",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Italian League for Research on Huntington Disease (LIRH) Foundation, Rome, Italy"
],
"type": "Organization"
},
"familyName": "Ceccarelli",
"givenName": "Consuelo",
"id": "sg:person.015270403163.69",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015270403163.69"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Pathophysiology and Transplantation, \u201cDino Ferrari\u201d Center, University of Milan, Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.4708.b",
"name": [
"Department of Pathophysiology and Transplantation, \u201cDino Ferrari\u201d Center, University of Milan, Milan, Italy"
],
"type": "Organization"
},
"familyName": "Pasquini",
"givenName": "Jacopo",
"id": "sg:person.0717305774.50",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717305774.50"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Division of Neuroscience San Raffaele Scientific Institute, Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.18887.3e",
"name": [
"Vita-Salute San Raffaele University, Milan, Italy",
"Division of Neuroscience San Raffaele Scientific Institute, Milan, Italy"
],
"type": "Organization"
},
"familyName": "Sassone",
"givenName": "Jenny",
"id": "sg:person.01155027220.52",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155027220.52"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Huntington and Rare Diseases Unit, Fondazione IRCCS Casa Sollievo Della Sofferenza Research Hospital, San Giovanni Rotondo, Italy",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Huntington and Rare Diseases Unit, Fondazione IRCCS Casa Sollievo Della Sofferenza Research Hospital, San Giovanni Rotondo, Italy"
],
"type": "Organization"
},
"familyName": "Squitieri",
"givenName": "Ferdinando",
"id": "sg:person.014054775037.73",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014054775037.73"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.418224.9",
"name": [
"Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy"
],
"type": "Organization"
},
"familyName": "Ciammola",
"givenName": "Andrea",
"id": "sg:person.0706107757.27",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0706107757.27"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Pathophysiology and Transplantation, \u201cDino Ferrari\u201d Center, University of Milan, Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.4708.b",
"name": [
"Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy",
"Department of Pathophysiology and Transplantation, \u201cDino Ferrari\u201d Center, University of Milan, Milan, Italy"
],
"type": "Organization"
},
"familyName": "Silani",
"givenName": "Vincenzo",
"id": "sg:person.01075440114.42",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01075440114.42"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.418224.9",
"name": [
"Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy"
],
"type": "Organization"
},
"familyName": "Poletti",
"givenName": "Barbara",
"id": "sg:person.01346310223.40",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01346310223.40"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/s10072-014-1921-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050634432",
"https://doi.org/10.1007/s10072-014-1921-3"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10072-017-2919-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1084023810",
"https://doi.org/10.1007/s10072-017-2919-4"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10072-016-2766-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009775786",
"https://doi.org/10.1007/s10072-016-2766-8"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10072-019-04154-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1123155773",
"https://doi.org/10.1007/s10072-019-04154-1"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10072-007-0791-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032134212",
"https://doi.org/10.1007/s10072-007-0791-3"
],
"type": "CreativeWork"
}
],
"datePublished": "2021-03-16",
"datePublishedReg": "2021-03-16",
"description": "IntroductionThe study aims at investigating psychometric properties of the Edinburgh cognitive and behavioural ALS screen (ECAS) in Parkinson\u2019s (PD) and Huntington\u2019s (HD) diseases. The sensitivity and specificity of the ECAS in highlighting HD and PD cognitive-behavioural features and in differentiating between these two populations and from healthy controls (HC) were evaluated. Moreover, correlations between the ECAS and traditional cognitive measures, together with core clinical features, were analysed.MethodsSeventy-three PD patients, 38 HD patients, and 49 education-matched healthy participants were enrolled. Participants were administered the ECAS, together with other cognitive screening tools and psychological questionnaires. Patients\u2019 behavioural assessment was also carried out with carers.ResultsThe ECAS distinguished between HD patients and HC and between the two clinical syndromes with high sensitivity and specificity. Even if the diagnostic accuracy of the ECAS in distinguishing between PD and HC was low, the PD cognitive phenotype was very well described by the ECAS performances. Convergent validity of the ECAS against other traditional cognitive screening was observed, as well as correlations with psychological aspects and typical clinical features, especially for the HD group.ConclusionsThe ECAS represents a rapid and feasible tool, useful also in other neurodegenerative disorders affecting verbal-motor abilities than the amyotrophic lateral sclerosis such as PD and HD. Clinical applications in these neurodegenerative conditions require further investigations and, probably, some adaptations of the original test.",
"genre": "article",
"id": "sg:pub.10.1007/s10072-021-05169-3",
"inLanguage": "en",
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1294956",
"issn": [
"1590-1874",
"1126-5442"
],
"name": "Neurological Sciences",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "12",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "42"
}
],
"keywords": [
"education-matched healthy participants",
"behavioral assessment",
"cognitive-behavioral features",
"traditional cognitive measures",
"Behavioural ALS Screen",
"cognitive screening tool",
"cognitive measures",
"cognitive phenotypes",
"core clinical features",
"neuropsychological assessment",
"psychological aspects",
"psychological questionnaires",
"cognitive screening",
"healthy controls",
"convergent validity",
"healthy participants",
"psychometric properties",
"clinical features",
"HD patients",
"ECAS",
"Huntington's disease",
"participants",
"typical clinical features",
"amyotrophic lateral sclerosis",
"original test",
"IntroductionThe study",
"PD patients",
"clinical syndrome",
"HD group",
"disorders",
"movement disorders",
"lateral sclerosis",
"neurodegenerative conditions",
"screening tool",
"neurodegenerative disorders",
"patients",
"diagnostic accuracy",
"disease",
"deficits",
"clinical applications",
"further investigation",
"carers",
"questionnaire",
"feasible tool",
"measures",
"validity",
"Parkinson's",
"specificity",
"ability",
"assessment",
"HD",
"sclerosis",
"syndrome",
"adaptation",
"aspects",
"sensitivity",
"performance",
"features",
"screening",
"correlation",
"test",
"phenotype",
"differentiating",
"screen",
"group",
"population",
"high sensitivity",
"ECA",
"study",
"control",
"accuracy",
"tool",
"Pd",
"investigation",
"Edinburgh",
"conditions",
"applications",
"properties",
"ALS screen",
"PD cognitive-behavioural features",
"MethodsSeventy-three PD patients",
"Patients\u2019 behavioural assessment",
"PD cognitive phenotype",
"ECAS performances",
"traditional cognitive screening",
"ConclusionsThe ECAS",
"verbal-motor abilities",
"verbal-motor deficits"
],
"name": "Compensating for verbal-motor deficits in neuropsychological assessment in movement disorders: sensitivity and specificity of the ECAS in Parkinson\u2019s and Huntington\u2019s diseases",
"pagination": "4997-5006",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1136444861"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s10072-021-05169-3"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"33728549"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s10072-021-05169-3",
"https://app.dimensions.ai/details/publication/pub.1136444861"
],
"sdDataset": "articles",
"sdDatePublished": "2022-01-01T19:02",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_914.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1007/s10072-021-05169-3"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10072-021-05169-3'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10072-021-05169-3'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10072-021-05169-3'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10072-021-05169-3'
This table displays all metadata directly associated to this object as RDF triples.
296 TRIPLES
22 PREDICATES
119 URIs
106 LITERALS
7 BLANK NODES