Validity of the Italian multiple sclerosis neuropsychological screening questionnaire View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2021-03-02

AUTHORS

Simone Migliore, Doriana Landi, Francesca Proietti, Giulia D’Aurizio, Ferdinando Squitieri, Giorgia Mataluni, Carolina Gabri Nicoletti, Giuseppe Curcio, Girolama Alessandra Marfia

ABSTRACT

The Multiple Sclerosis Neuropsychological Questionnaire (MSNQ) is a brief questionnaire useful for screening patients with multiple sclerosis (MS) at risk for cognitive impairment. It includes a patient self-assessment (MSNQ-p) and a section for the caregiver (informant) (MSNQ-i). This study’s aim was to validate the Italian version of MSNQ and to compare MSNQ scores with Symbol Digit Modality Test (SDMT), Beck Depression Inventory (BDI), and Expanded Disability Status Scale (EDSS) score, measuring cognitive skills, mood status, and physical disability respectively. We enrolled 122 MS patients (and related caregivers) at MS center of Tor Vergata University Hospital of Rome. The final study sample consisted of 122 patients with MS (90 relapsing-remitting, 24 secondary progressive, and 8 primary progressive). Our results highlighted that MSNQ has a unidimensional factor structure. Correlational analyses found a good correlation between both versions (MSNQ-p and MSNQ-i) of the questionnaire. Both MSNQ-p and MSNQ-i were correlated with clinical variables, specifically with cognitive impairment, mood disorder, and with disability. The Italian version of MSNQ is reliable and useful as screening tool to identify MS patients at high risk of cognitive impairment. More... »

PAGES

4583-4589

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10072-021-05141-1

DOI

http://dx.doi.org/10.1007/s10072-021-05141-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1135850703

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/33651198


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