Small-fiber neuropathy definition, diagnosis, and treatment. View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04-09

AUTHORS

Natalia Y Basantsova, Anna A Starshinova, Amir Dori, Yulia S Zinchenko, Piotr K Yablonskiy, Yehuda Shoenfeld

ABSTRACT

In the last 30 years, improvement of diagnostic methods enabled routine evaluation of small A-delta and C nerve fibers impairment, which results with the clinical condition known as a small-fiber neuropathy (SFN). This syndrome develops as a result of metabolic, toxic, immune-mediated, or genetic factors. The main clinical features include neuropathic pain and autonomic disturbance, which are occasionally disclaimed due to outstanding fatigue, daily performance decline, anxiety, and depression. As clinical, neurological, nerve conduction, and electromyography studies are commonly normal, diagnosis often depends on the finding of decreased intra-epidermal density of nerve fibers, per skin biopsy. This review highlights the etiology, clinical, diagnostic aspects, and SFN treatment. More... »

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10072-019-03871-x

DOI

http://dx.doi.org/10.1007/s10072-019-03871-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113327993

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30968230


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