A Delphi consensus statement of the Neuropathic Pain Special Interest Group of the Italian Neurological Society on pharmacoresistant neuropathic pain View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04-02

AUTHORS

P. Ciaramitaro, G. Cruccu, M. de Tommaso, G. Devigili, D. Fornasari, P. Geppetti, M. Lacerenza, G. Lauria, S. Mameli, P. Marchettini, M. Nolano, E. Polati, V. Provitera, M. Romano, C. Solaro, S. Tamburin, V. Tugnoli, M. Valeriani, Andrea Truini, On behalf of the Neuropathic Pain Special Interest Group of the Italian Neurological Society

ABSTRACT

To improve patient care and help clinical research, the Neuropathic Pain Special Interest Group of the Italian Neurological Society appointed a task force to elaborate a consensus statement on pharmacoresistant neuropathic pain. The task force included 19 experts in neuropathic pain. These experts participated in a Delphi survey consisting of three consecutive rounds of questions and a face-to-face meeting, designed to achieve a consensus definition of pharmacoresistant neuropathic pain. In the three rounds of questions, the participants identified and described the main distinguishing features of pharmacoresistance. In the face-to-face meeting the participants discussed the clinical features determining pharmacoresistance. They finally agreed that neuropathic pain is pharmacoresistant when "the patient does not reach the 50% reduction of pain or an improvement of at least 2 points in the Patient Global Impression of Change, having used all drug classes indicated as first, second, or third line in the most recent and widely agreed international guidelines, for at least 1 month after titration to the highest tolerable dose." Our consensus statement might be useful for identifying eligible patients for invasive treatments, and selecting patients in pharmacological trials, thus improving patient care and helping clinical research. More... »

PAGES

1-7

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10072-019-03870-y

DOI

http://dx.doi.org/10.1007/s10072-019-03870-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113179978

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30941628


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RDF/XML is a standard XML format for linked data.

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291 https://www.grid.ac/institutes/grid.5117.2 schema:alternateName Aalborg University
292 schema:name Center for Sensory-Motor Interaction, Aalborg University, Aalborg, Denmark
293 Division of Neurology, Ospedale Pediatrico Bambino Gesú, IRCCS, Rome, Italy
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295 https://www.grid.ac/institutes/grid.5611.3 schema:alternateName University of Verona
296 schema:name Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy
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298 https://www.grid.ac/institutes/grid.7644.1 schema:alternateName University of Bari Aldo Moro
299 schema:name Applied Neurophysiology and Pain Unit, Basic Medical Science, Neuroscience and Sensory System-SMBNOS-Department, Aldo Moro University, Bari, Italy
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301 https://www.grid.ac/institutes/grid.7841.a schema:alternateName Sapienza University of Rome
302 schema:name Department of Human Neuroscience, University Sapienza, Viale Università 30, 00185, Rome, Italy
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304 https://www.grid.ac/institutes/grid.8404.8 schema:alternateName University of Florence
305 schema:name Department of Health Sciences, Section of Clinical Pharmacology and Headache Center, University of Florence, Florence, Italy
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