Neurologic signs in relation to cognitive function in subcortical ischemic vascular dementia: a CREDOS (Clinical Research Center for Dementia of ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-11-09

AUTHORS

Seong Hye Choi, SangYun Kim, Seol-Heui Han, Duk L. Na, Doh-Kwan Kim, Hae-Kwan Cheong, Jae-Hong Lee, Seong Yoon Kim, Chang Hyung Hong, So Young Moon, Jay C. Kwon, Jung Eun Kim, Jee H. Jeong, Hae Ri Na, Kyung Ryeol Cha, Sang Won Seo, Yong S. Shim, Jun-Young Lee, Kyung Won Park

ABSTRACT

The objective of this study was to investigate the relationship between neurologic signs and cognitive dysfunction in subcortical ischemic vascular dementia (SIVD). 121 patients with SIVD were recruited from multiple nationwide hospitals. The patients’ neurologic signs were evaluated using the Focal Neurologic Sign Score (FNSS). The FNSS scores did not correlate with the composite neuropsychology scores and Korean Mini-Mental State Examination scores. The FNSS scores correlated with the letter fluency and Rey–Osterrieth Complex Figure (ROCF) copy scores. Using a multivariate regression analysis controlled for age, sex, and educational level, the FNSS scores had a significant relationship with the letter fluency test scores (R2 = 0.08, β = −2.28, p = 0.02) and ROCF copy scores (R2 = 0.08, β = −0.42, p = 0.03). These findings suggest that the neurologic signs in patients with SIVD do not correlate with global cognitive functions; however, these signs do correlate with executive dysfunction in these patients. More... »

PAGES

839-846

Journal

TITLE

Neurological Sciences

ISSUE

4

VOLUME

33

Author Affiliations

  • Department of Neurology, Inha University School of Medicine, Incheon, South Korea
  • Department of Neurology, Seoul National University Bundang Hospital, Gumi-dong 300, Bundang-gu, 463-707, Seongnam, Gyeonggi-do, South Korea
  • Department of Neurology, Konkuk University School of Medicine, Seoul, South Korea
  • Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
  • Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
  • Department of Social and Preventive Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
  • Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
  • Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
  • Department of Psychiatry, Ajou University School of Medicine, Suwon, South Korea
  • Department of Neurology, Ajou University School of Medicine, Suwon, South Korea
  • Department of Neurology, Changwon Fatima Hospital, Changwon, South Korea
  • Department of Neurology, Seoul National University College of Medicine, Seoul, South Korea
  • Department of Neurology, Ewha Womans University School of Medicine, Seoul, South Korea
  • Department of Neurology, Bobath Memorial Hospital, Seongnam, South Korea
  • Department of Psychiatry, MunGyeong Jeil General Hospital, MunGyeong, South Korea
  • Department of Neurology, School of Medicine, Bucheon St. Mary’s Hospital, The Catholic University of Korea, Bucheon, South Korea
  • Department of Psychiatry, Boramae Hospital, Seoul National University, Seoul, South Korea
  • Department of Neurology, Dong-A University College of Medicine, Pusan, South Korea
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s10072-011-0845-4

    DOI

    http://dx.doi.org/10.1007/s10072-011-0845-4

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1010023014

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22068220


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