Increased risk of sudden sensory neural hearing loss in patients with rheumatoid arthritis: a longitudinal follow-up study using a national ... View Full Text


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Article Info

DATE

2019-03

AUTHORS

Sang-Yeon Lee, Il Gyu Kong, Dong Jun Oh, Hyo Geun Choi

ABSTRACT

To evaluate the association between sudden sensorineural hearing loss (SSNHL) and rheumatoid arthritis (RA) among a national sample cohort from Korea. Data were collected from 2002 through 2013 for individuals aged ≥ 20 years in the Korean National Health Insurance Service (NHIS)-National Sample Cohort. We extracted the data from RA patients (n = 7619) and 1:4-matched controls (n = 30,476) and analyzed the occurrence of SSNHL. Matching was performed based on age, sex, income, region of residence, and medical history. RA was diagnosed based on International Classification of Disease-10 (ICD-10) codes (M05 or M06) and prescriptions for the antirheumatic drugs. SSNHL was diagnosed based on the relevant ICD-10 code (H912). Among the SSNHL participants, we included only those who had undergone an audiometry exam (claim codes: E6931-E6937, F6341-F6348) and received treatment with steroids. The crude and adjusted hazard ratios (HRs) were calculated using Cox-proportional hazard models, and the 95% confidence intervals (CIs) were determined. Subgroup analyses based on age and sex were also performed. The rate of SSNHL in the RA group (0.8% [62/7619]) was higher than that in the control group (0.6% [177/30,476], P = 0.021). The crude and adjusted HRs for SSNHL were 1.40 (95% CI = 1.05-1.87) and 1.39 (95% CI = 1.04-1.86), respectively, in the RA group (each P < 0.05). The relationship between RA and SSNHL was observed primarily in patients aged ≥ 50 years and men. The risk of SSNHL is higher in patients with RA. More... »

PAGES

683-689

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10067-018-4333-6

DOI

http://dx.doi.org/10.1007/s10067-018-4333-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1107642945

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30324407


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