Ontology type: schema:ScholarlyArticle
2009-05
AUTHORSYoun Wook Chung, Daewon Jeong, Ok Jeong Noh, Yong Hwan Park, Soo Im Kang, Min Goo Lee, Tae-Hoon Lee, Moon Bin Yim, Ick Young Kim
ABSTRACTIt has been reported that selenoprotein W (SelW) mRNA is highly expressed in the developing central nerve system of rats, and its expression is maintained until the early postnatal stage. We here found that SelW protein significantly increased in mouse brains of postnatal day 8 and 20 relative to embryonic day 15. This was accompanied by increased expression of SOD1 and SOD2. When the expression of SelW in primary cultured cells derived from embryonic cerebral cortex was knocked down with small interfering RNAs (siRNAs), SelW siRNA-transfected neuronal cells were more sensitive to the oxidative stress induced by treatment of H2O2 than control cells. TUNEL assays revealed that H2O2-induced apoptotic cell death occurred at a higher frequency in the siRNA-transfected cells than in the control cells. Taken together, our findings suggest that SelW plays an important role in protection of neurons from oxidative stress during neuronal development. More... »
PAGES609-613
http://scigraph.springernature.com/pub.10.1007/s10059-009-0074-3
DOIhttp://dx.doi.org/10.1007/s10059-009-0074-3
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1032202044
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/19466610
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Neurosciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Animals",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Antioxidants",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Apoptosis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cells, Cultured",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cerebral Cortex",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Embryo, Mammalian",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Gene Expression Profiling",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Gene Expression Regulation, Developmental",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Hydrogen Peroxide",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Mice",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Nervous System",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Neurons",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Oxidative Stress",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "RNA, Small Interfering",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Selenoprotein W",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Superoxide Dismutase",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Superoxide Dismutase-1",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "National Heart Lung and Blood Institute",
"id": "https://www.grid.ac/institutes/grid.279885.9",
"name": [
"Laboratory of Cellular and Molecular Biochemistry, School of Life Sciences and Biotechnology, Korea University, 136-701, Seoul, Korea",
"Laboratory of Biochemistry, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 50, 9000 Rockville Pike, 20892, Bethesda, MD, USA"
],
"type": "Organization"
},
"familyName": "Chung",
"givenName": "Youn Wook",
"id": "sg:person.01130211212.62",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01130211212.62"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Yeungnam University",
"id": "https://www.grid.ac/institutes/grid.413028.c",
"name": [
"Department of Microbiology and Aging-associated Disease Research Center, Yeungnam University College of Medicine, 705-030, Daegu, Korea"
],
"type": "Organization"
},
"familyName": "Jeong",
"givenName": "Daewon",
"id": "sg:person.0733074237.10",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733074237.10"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Korea University",
"id": "https://www.grid.ac/institutes/grid.222754.4",
"name": [
"Laboratory of Cellular and Molecular Biochemistry, School of Life Sciences and Biotechnology, Korea University, 136-701, Seoul, Korea"
],
"type": "Organization"
},
"familyName": "Noh",
"givenName": "Ok Jeong",
"id": "sg:person.01342005766.26",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342005766.26"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Korea University",
"id": "https://www.grid.ac/institutes/grid.222754.4",
"name": [
"Laboratory of Cellular and Molecular Biochemistry, School of Life Sciences and Biotechnology, Korea University, 136-701, Seoul, Korea"
],
"type": "Organization"
},
"familyName": "Park",
"givenName": "Yong Hwan",
"id": "sg:person.01214235634.87",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214235634.87"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Korea University",
"id": "https://www.grid.ac/institutes/grid.222754.4",
"name": [
"Laboratory of Cellular and Molecular Biochemistry, School of Life Sciences and Biotechnology, Korea University, 136-701, Seoul, Korea"
],
"type": "Organization"
},
"familyName": "Kang",
"givenName": "Soo Im",
"id": "sg:person.01240703661.14",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01240703661.14"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Korea University",
"id": "https://www.grid.ac/institutes/grid.222754.4",
"name": [
"Laboratory of Cellular and Molecular Biochemistry, School of Life Sciences and Biotechnology, Korea University, 136-701, Seoul, Korea"
],
"type": "Organization"
},
"familyName": "Lee",
"givenName": "Min Goo",
"id": "sg:person.01172226140.23",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01172226140.23"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Chonnam National University",
"id": "https://www.grid.ac/institutes/grid.14005.30",
"name": [
"School of Dentistry, Dental Science Research Institute, The 2nd Stage of Brain Korea 21 for the Dental School, Chonnam National University, 500-757, Gwangju, Korea"
],
"type": "Organization"
},
"familyName": "Lee",
"givenName": "Tae-Hoon",
"id": "sg:person.01370165430.35",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01370165430.35"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "National Heart Lung and Blood Institute",
"id": "https://www.grid.ac/institutes/grid.279885.9",
"name": [
"Laboratory of Biochemistry, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 50, 9000 Rockville Pike, 20892, Bethesda, MD, USA"
],
"type": "Organization"
},
"familyName": "Yim",
"givenName": "Moon Bin",
"id": "sg:person.015346307631.10",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015346307631.10"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Korea University",
"id": "https://www.grid.ac/institutes/grid.222754.4",
"name": [
"Laboratory of Cellular and Molecular Biochemistry, School of Life Sciences and Biotechnology, Korea University, 136-701, Seoul, Korea"
],
"type": "Organization"
},
"familyName": "Kim",
"givenName": "Ick Young",
"id": "sg:person.01204653250.90",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204653250.90"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1038/ng713",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003049110",
"https://doi.org/10.1038/ng713"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ng713",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003049110",
"https://doi.org/10.1038/ng713"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1146/annurev.nutr.24.012003.132120",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004110465"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0891-5849(99)00258-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005945987"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1074/jbc.m701605200",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006849017"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jinorgbio.2006.05.018",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010651022"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0166-2236(99)01543-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013016024"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1042/bj3460001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015629974"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1042/bj3460001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015629974"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/mcb.22.5.1402-1411.2002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015855877"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/hmg/ddg115",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016240328"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0162-0134(95)00045-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018872397"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.brainresrev.2004.03.004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021398364"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1023/a:1007065829068",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025272410",
"https://doi.org/10.1023/a:1007065829068"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1006/abbi.1998.0949",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028312404"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0076-6879(02)47017-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028542797"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0076-6879(02)47017-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028542797"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0891-5849(99)00173-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029006878"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1006/bbrc.1997.6618",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029067299"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1749-6632.1994.tb21784.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030471938"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0306-4522(87)90068-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030867725"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0306-4522(87)90068-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030867725"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/353273a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031895527",
"https://doi.org/10.1038/353273a0"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0014-5793(73)80755-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032005428"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/embo-reports/kvd033",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033315645"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/nar/24.3.464",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036954816"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0306-4522(96)00222-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037227704"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.73.8.2659",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038256651"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1042/bj20070929",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038787614"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1042/bj20070929",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038787614"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.83.13.4650",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039815541"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/emboj/19.17.4796",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039923891"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1096/fj.06-075820",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041275509"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0014-5793(02)02628-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045847272"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0896-6273(00)00147-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048816054"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1146/annurev.nutr.19.1.1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050364473"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1074/jbc.m705410200",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053225171"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1021/bi602462q",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1055206825"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1021/bi602462q",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1055206825"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1042/0264-6021:3460001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1056714519"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1086/342719",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1058639499"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.1083516",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062448022"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.179.4073.588",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062506517"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1076818327",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1077641672",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1078935743",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1096/fasebj.9.5.7896009",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1082555167"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082769140",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jn/127.3.394",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1083064324"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jn/127.11.2165",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1083165849"
],
"type": "CreativeWork"
}
],
"datePublished": "2009-05",
"datePublishedReg": "2009-05-01",
"description": "It has been reported that selenoprotein W (SelW) mRNA is highly expressed in the developing central nerve system of rats, and its expression is maintained until the early postnatal stage. We here found that SelW protein significantly increased in mouse brains of postnatal day 8 and 20 relative to embryonic day 15. This was accompanied by increased expression of SOD1 and SOD2. When the expression of SelW in primary cultured cells derived from embryonic cerebral cortex was knocked down with small interfering RNAs (siRNAs), SelW siRNA-transfected neuronal cells were more sensitive to the oxidative stress induced by treatment of H2O2 than control cells. TUNEL assays revealed that H2O2-induced apoptotic cell death occurred at a higher frequency in the siRNA-transfected cells than in the control cells. Taken together, our findings suggest that SelW plays an important role in protection of neurons from oxidative stress during neuronal development.",
"genre": "research_article",
"id": "sg:pub.10.1007/s10059-009-0074-3",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1115754",
"issn": [
"1016-8478",
"0219-1032"
],
"name": "Molecules and Cells",
"type": "Periodical"
},
{
"issueNumber": "5",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "27"
}
],
"name": "Antioxidative role of selenoprotein W in oxidant-induced mouse embryonic neuronal cell death",
"pagination": "609-613",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"99673e25530e05be073dbe34b22a5ac96b00bbbb49748d112060123cbdd00ed6"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"19466610"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"9610936"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s10059-009-0074-3"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1032202044"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s10059-009-0074-3",
"https://app.dimensions.ai/details/publication/pub.1032202044"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T14:28",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000373_0000000373/records_13081_00000001.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007/s10059-009-0074-3"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s10059-009-0074-3'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s10059-009-0074-3'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s10059-009-0074-3'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s10059-009-0074-3'
This table displays all metadata directly associated to this object as RDF triples.
334 TRIPLES
21 PREDICATES
90 URIs
38 LITERALS
26 BLANK NODES