Evaluation of artificial pancreas technology for continuous blood glucose monitoring in dogs View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-04-14

AUTHORS

Akihiro Mori, Peter Lee, Takeshi Yokoyama, Hitomi Oda, Kaori Saeki, Yohei Miki, Satoshi Nozawa, Daigo Azakami, Yutaka Momota, Yuki Makino, Takako Matsubara, Motohisa Osaka, Katsumi Ishioka, Toshiro Arai, Toshinori Sako

ABSTRACT

Artificial pancreas technology, involving “closed-loop” controls with real-time blood glucose monitoring, has been increasing in reliability as its potential for clinical use and application grows. One such device, based on this technology, is the STG-22 (Nikkiso Co., Ltd., Tokyo, Japan) artificial pancreas apparatus. In order to assess the reliability and accuracy of the device for measuring blood glucose, it is important to compare its readings to those obtained using a ‘gold standard’ method, such as the hexokinase method. Therefore, in the present study, canine blood [glucose] measurements using the STG-22 were compared to those obtained using a previously established commercial reagent, Quickauto-Neo GLU-HK. Furthermore, two different sample types (whole blood versus plasma constituent) were compared to determine which sample type results in more accurate and optimal readings with the STG-22. Given that the STG-22 was not primarily designed for canine blood samples, results for canine blood samples were not accurate. Measurements performed by the STG-22 with whole blood were significantly lower than reference [glucose] counterparts. Alternatively, an opposite trend was observed with plasma measurements that were significantly higher. A conversion format using the following formula, Hexokinase [glucose] = STG-22 [glucose] × 1.407 + 1.532, was observed with canine samples in our study. More... »

PAGES

133

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s10047-011-0560-1

DOI

http://dx.doi.org/10.1007/s10047-011-0560-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1025721824

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21491113


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25 Quickauto-Neo GLU
26 STG-22
27 STG-22 (Nikkiso Co., Ltd., Tokyo, Japan) artificial pancreas apparatus
28 accuracy
29 apparatus
30 applications
31 artificial pancreas apparatus
32 artificial pancreas technology
33 blood
34 blood glucose
35 blood glucose monitoring
36 blood measurements
37 blood samples
38 canine blood [glucose] measurements
39 canine blood samples
40 canine samples
41 clinical use
42 commercial reagents
43 continuous blood glucose monitoring
44 control
45 conversion format
46 counterparts
47 devices
48 different sample types
49 dogs
50 evaluation
51 format
52 formula
53 glucose
54 glucose monitoring
55 gold standard
56 hexokinase
57 hexokinase method
58 measurements
59 method
60 monitoring
61 opposite trend
62 optimal reading
63 order
64 pancreas apparatus
65 pancreas technology
66 plasma measurements
67 potential
68 present study
69 reading
70 reagents
71 real-time blood glucose monitoring
72 reference counterparts
73 reliability
74 results
75 sample types
76 samples
77 standards
78 study
79 such devices
80 technology
81 trends
82 types
83 use
84 whole blood
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