A novel histopathological scoring system for patients with oral squamous cell carcinoma View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-01-23

AUTHORS

Ali-Farid Safi, Kathrin Grochau, Uta Drebber, Volker Schick, Oliver Thiele, Tim Backhaus, Hans-Joachim Nickenig, Joachim E. Zöller, Matthias Kreppel

ABSTRACT

ObjectivesTumor invasion into blood and/or lymphatic vessels, perineural invasion, and histopathological grading are evaluated to assess the biological aggressiveness of oral squamous cell carcinoma (OSCC). We aim to assess the prognostic impact of a novel scoring system, based upon the aforementioned histological parameters.Materials and methodsRetrospective chart review of 334 patients with treatment-naive squamous cell carcinoma of the oral cavity. Statistical analysis was performed using univariate and multivariate analysis. Histological grade G1 or G2 were assigned 0 points and G3 or G4 1 point. Invasion of the lymphatic vessels, blood vessels, or perineural space was given 1 point. Zero points were given, when invasion was not detectable. The final score was conducted through addition of each parameter. Therefore, our scoring system ranged between 0 and 4 points.ResultsT-classification (p < 0.001), N-classification (p < 0.001), UICC stage (p < 0.001), extracapsular spread (p < 0.001), locoregional recurrence (p < 0.001), and overall survival (p < 0.001) were significantly associated with the OSCC-Histoscore. In multivariate analysis, T-classification (p = 0.001), N-classification (p = 0.039), resection margins (p = 0.038), and OSCC-Histoscore (p < 0.001) were independent prognostic markers for overall survival rate.ConclusionOur presented OSCC-Histoscore serves as a strong independent prognostic parameter for 5-year overall survival (OS) and predicts OS better than T-classification, N-classification, and resection margins.Clinical relevanceOur presented histoscore improves prediction of the overall survival of patients with OSCC. More... »

PAGES

3759-3765

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00784-019-02804-4

DOI

http://dx.doi.org/10.1007/s00784-019-02804-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111634971

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30673863


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carcinoma, Squamous Cell", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mouth Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Recurrence, Local", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Staging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Center for Integrated Oncology Cologne-Bonn, Cologne, Germany", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department for Oral and Craniomaxillofacial Plastic Surgery, University of Cologne, Kerpener Stra\u00dfe 62, 50931, Cologne, Germany", 
            "Center for Integrated Oncology Cologne-Bonn, Cologne, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Safi", 
        "givenName": "Ali-Farid", 
        "id": "sg:person.0620620701.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0620620701.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Center for Integrated Oncology Cologne-Bonn, Cologne, Germany", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department for Oral and Craniomaxillofacial Plastic Surgery, University of Cologne, Kerpener Stra\u00dfe 62, 50931, Cologne, Germany", 
            "Center for Integrated Oncology Cologne-Bonn, Cologne, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Grochau", 
        "givenName": "Kathrin", 
        "id": "sg:person.015436160633.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015436160633.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department for Pathology, University of Cologne, Cologne, Germany", 
          "id": "http://www.grid.ac/institutes/grid.6190.e", 
          "name": [
            "Center for Integrated Oncology Cologne-Bonn, Cologne, Germany", 
            "Department for Pathology, University of Cologne, Cologne, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Drebber", 
        "givenName": "Uta", 
        "id": "sg:person.01365553214.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365553214.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department for Anesthesiology and Intensive Care, University of Cologne, Cologne, Germany", 
          "id": "http://www.grid.ac/institutes/grid.6190.e", 
          "name": [
            "Center for Integrated Oncology Cologne-Bonn, Cologne, Germany", 
            "Department for Anesthesiology and Intensive Care, University of Cologne, Cologne, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schick", 
        "givenName": "Volker", 
        "id": "sg:person.01061545106.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01061545106.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department for Oral and Maxillofacial Plastic Surgery, Klinikum Ludwigshafen, Ludwigshafen, Germany", 
          "id": "http://www.grid.ac/institutes/grid.413225.3", 
          "name": [
            "Department for Oral and Maxillofacial Plastic Surgery, Klinikum Ludwigshafen, Ludwigshafen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Thiele", 
        "givenName": "Oliver", 
        "id": "sg:person.01223410311.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223410311.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Center for Integrated Oncology Cologne-Bonn, Cologne, Germany", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department for Oral and Craniomaxillofacial Plastic Surgery, University of Cologne, Kerpener Stra\u00dfe 62, 50931, Cologne, Germany", 
            "Center for Integrated Oncology Cologne-Bonn, Cologne, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Backhaus", 
        "givenName": "Tim", 
        "id": "sg:person.0775745322.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775745322.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Center for Integrated Oncology Cologne-Bonn, Cologne, Germany", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department for Oral and Craniomaxillofacial Plastic Surgery, University of Cologne, Kerpener Stra\u00dfe 62, 50931, Cologne, Germany", 
            "Center for Integrated Oncology Cologne-Bonn, Cologne, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nickenig", 
        "givenName": "Hans-Joachim", 
        "id": "sg:person.01365155331.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365155331.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Center for Integrated Oncology Cologne-Bonn, Cologne, Germany", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department for Oral and Craniomaxillofacial Plastic Surgery, University of Cologne, Kerpener Stra\u00dfe 62, 50931, Cologne, Germany", 
            "Center for Integrated Oncology Cologne-Bonn, Cologne, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Z\u00f6ller", 
        "givenName": "Joachim E.", 
        "id": "sg:person.01117726644.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117726644.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Center for Integrated Oncology Cologne-Bonn, Cologne, Germany", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department for Oral and Craniomaxillofacial Plastic Surgery, University of Cologne, Kerpener Stra\u00dfe 62, 50931, Cologne, Germany", 
            "Center for Integrated Oncology Cologne-Bonn, Cologne, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kreppel", 
        "givenName": "Matthias", 
        "id": "sg:person.01153154766.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153154766.22"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/sj.bjc.6603152", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010492859", 
          "https://doi.org/10.1038/sj.bjc.6603152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00428-010-0915-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024935977", 
          "https://doi.org/10.1007/s00428-010-0915-7"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-01-23", 
    "datePublishedReg": "2019-01-23", 
    "description": "ObjectivesTumor invasion into blood and/or lymphatic vessels, perineural invasion, and histopathological grading are evaluated to assess the biological aggressiveness of oral squamous cell carcinoma (OSCC). We aim to assess the prognostic impact of a novel scoring system, based upon the aforementioned histological parameters.Materials and methodsRetrospective chart review of 334 patients with treatment-naive squamous cell carcinoma of the oral cavity. Statistical analysis was performed using univariate and multivariate analysis. Histological grade G1 or G2 were assigned 0 points and G3 or G4 1 point. Invasion of the lymphatic vessels, blood vessels, or perineural space was given 1 point. Zero points were given, when invasion was not detectable. The final score was conducted through addition of each parameter. Therefore, our scoring system ranged between 0 and 4 points.ResultsT-classification (p\u2009<\u20090.001), N-classification (p\u2009<\u20090.001), UICC stage (p\u2009<\u20090.001), extracapsular spread (p\u2009<\u20090.001), locoregional recurrence (p\u2009<\u20090.001), and overall survival (p\u2009<\u20090.001) were significantly associated with the OSCC-Histoscore. In multivariate analysis, T-classification (p\u2009=\u20090.001), N-classification (p\u2009=\u20090.039), resection margins (p\u2009=\u20090.038), and OSCC-Histoscore (p\u2009<\u20090.001) were independent prognostic markers for overall survival rate.ConclusionOur presented OSCC-Histoscore serves as a strong independent prognostic parameter for 5-year overall survival (OS) and predicts OS better than T-classification, N-classification, and resection margins.Clinical relevanceOur presented histoscore improves prediction of the overall survival of patients with OSCC.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00784-019-02804-4", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1116831", 
        "issn": [
          "1432-6981", 
          "1436-3771"
        ], 
        "name": "Clinical Oral Investigations", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "10", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "23"
      }
    ], 
    "keywords": [
      "oral squamous cell carcinoma", 
      "squamous cell carcinoma", 
      "overall survival", 
      "cell carcinoma", 
      "resection margins", 
      "scoring system", 
      "MethodsRetrospective chart review", 
      "overall survival rate", 
      "strong independent prognostic parameter", 
      "independent prognostic marker", 
      "independent prognostic parameter", 
      "histopathological scoring system", 
      "lymphatic vessels", 
      "novel scoring system", 
      "histological grade G1", 
      "chart review", 
      "extracapsular spread", 
      "locoregional recurrence", 
      "perineural invasion", 
      "prognostic impact", 
      "UICC stage", 
      "prognostic parameters", 
      "histological parameters", 
      "grade G1", 
      "perineural space", 
      "prognostic marker", 
      "histopathological grading", 
      "biological aggressiveness", 
      "survival rate", 
      "oral cavity", 
      "multivariate analysis", 
      "carcinoma", 
      "patients", 
      "blood vessels", 
      "survival", 
      "invasion", 
      "vessels", 
      "final score", 
      "recurrence", 
      "statistical analysis", 
      "blood", 
      "univariate", 
      "scores", 
      "grading", 
      "aggressiveness", 
      "markers", 
      "ConclusionOur", 
      "review", 
      "G3", 
      "classification", 
      "G1", 
      "G2", 
      "margin", 
      "analysis", 
      "spread", 
      "rate", 
      "cavity", 
      "stage", 
      "point", 
      "addition", 
      "impact", 
      "parameters", 
      "system", 
      "materials", 
      "prediction", 
      "space", 
      "ObjectivesTumor invasion", 
      "aforementioned histological parameters", 
      "treatment-naive squamous cell carcinoma", 
      "G4 1 point", 
      "OSCC-Histoscore", 
      "Clinical relevanceOur", 
      "relevanceOur", 
      "novel histopathological scoring system"
    ], 
    "name": "A novel histopathological scoring system for patients with oral squamous cell carcinoma", 
    "pagination": "3759-3765", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1111634971"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00784-019-02804-4"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30673863"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00784-019-02804-4", 
      "https://app.dimensions.ai/details/publication/pub.1111634971"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-11-01T18:37", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211101/entities/gbq_results/article/article_816.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00784-019-02804-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00784-019-02804-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00784-019-02804-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00784-019-02804-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00784-019-02804-4'


 

This table displays all metadata directly associated to this object as RDF triples.

246 TRIPLES      22 PREDICATES      111 URIs      101 LITERALS      16 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00784-019-02804-4 schema:about N01a92b3881ef455fb74602736d32cf11
2 N4e84840b7bcb42c6aca602666d03258b
3 N602c0c013f2c4f9f9d3ca5b2f1f6e715
4 N62f9f2e57623483ba88d5e6bad178e6c
5 N7a467e0e3d544020a7a85722c2999118
6 Na1af0ed3e01646028d6ff8d4e9dfeb0e
7 Nb93ddf664b3b487c95cdea2709f256c3
8 Nc96a99e3c7db4b6197d0e65fd66401bf
9 Nf72acfb1bf834cb3be79108a54fc0aaf
10 anzsrc-for:11
11 anzsrc-for:1112
12 schema:author N3b5890c8b5094404ad788f00cbd8ce5c
13 schema:citation sg:pub.10.1007/s00428-010-0915-7
14 sg:pub.10.1038/sj.bjc.6603152
15 schema:datePublished 2019-01-23
16 schema:datePublishedReg 2019-01-23
17 schema:description ObjectivesTumor invasion into blood and/or lymphatic vessels, perineural invasion, and histopathological grading are evaluated to assess the biological aggressiveness of oral squamous cell carcinoma (OSCC). We aim to assess the prognostic impact of a novel scoring system, based upon the aforementioned histological parameters.Materials and methodsRetrospective chart review of 334 patients with treatment-naive squamous cell carcinoma of the oral cavity. Statistical analysis was performed using univariate and multivariate analysis. Histological grade G1 or G2 were assigned 0 points and G3 or G4 1 point. Invasion of the lymphatic vessels, blood vessels, or perineural space was given 1 point. Zero points were given, when invasion was not detectable. The final score was conducted through addition of each parameter. Therefore, our scoring system ranged between 0 and 4 points.ResultsT-classification (p < 0.001), N-classification (p < 0.001), UICC stage (p < 0.001), extracapsular spread (p < 0.001), locoregional recurrence (p < 0.001), and overall survival (p < 0.001) were significantly associated with the OSCC-Histoscore. In multivariate analysis, T-classification (p = 0.001), N-classification (p = 0.039), resection margins (p = 0.038), and OSCC-Histoscore (p < 0.001) were independent prognostic markers for overall survival rate.ConclusionOur presented OSCC-Histoscore serves as a strong independent prognostic parameter for 5-year overall survival (OS) and predicts OS better than T-classification, N-classification, and resection margins.Clinical relevanceOur presented histoscore improves prediction of the overall survival of patients with OSCC.
18 schema:genre article
19 schema:inLanguage en
20 schema:isAccessibleForFree false
21 schema:isPartOf N12b90891b965480eb78a47ad52a1c146
22 N60b05417721f4c5e9757a1e7a49d769b
23 sg:journal.1116831
24 schema:keywords Clinical relevanceOur
25 ConclusionOur
26 G1
27 G2
28 G3
29 G4 1 point
30 MethodsRetrospective chart review
31 OSCC-Histoscore
32 ObjectivesTumor invasion
33 UICC stage
34 addition
35 aforementioned histological parameters
36 aggressiveness
37 analysis
38 biological aggressiveness
39 blood
40 blood vessels
41 carcinoma
42 cavity
43 cell carcinoma
44 chart review
45 classification
46 extracapsular spread
47 final score
48 grade G1
49 grading
50 histological grade G1
51 histological parameters
52 histopathological grading
53 histopathological scoring system
54 impact
55 independent prognostic marker
56 independent prognostic parameter
57 invasion
58 locoregional recurrence
59 lymphatic vessels
60 margin
61 markers
62 materials
63 multivariate analysis
64 novel histopathological scoring system
65 novel scoring system
66 oral cavity
67 oral squamous cell carcinoma
68 overall survival
69 overall survival rate
70 parameters
71 patients
72 perineural invasion
73 perineural space
74 point
75 prediction
76 prognostic impact
77 prognostic marker
78 prognostic parameters
79 rate
80 recurrence
81 relevanceOur
82 resection margins
83 review
84 scores
85 scoring system
86 space
87 spread
88 squamous cell carcinoma
89 stage
90 statistical analysis
91 strong independent prognostic parameter
92 survival
93 survival rate
94 system
95 treatment-naive squamous cell carcinoma
96 univariate
97 vessels
98 schema:name A novel histopathological scoring system for patients with oral squamous cell carcinoma
99 schema:pagination 3759-3765
100 schema:productId N369ac13130bd4a1493f28c55b09c9d16
101 Na4cd22c6bcb54a13a48f9f917b4d76f0
102 Nd1186e3896b1486d8d4ed93bca00627b
103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1111634971
104 https://doi.org/10.1007/s00784-019-02804-4
105 schema:sdDatePublished 2021-11-01T18:37
106 schema:sdLicense https://scigraph.springernature.com/explorer/license/
107 schema:sdPublisher N5f5d411749d4459a8f99775c325cf219
108 schema:url https://doi.org/10.1007/s00784-019-02804-4
109 sgo:license sg:explorer/license/
110 sgo:sdDataset articles
111 rdf:type schema:ScholarlyArticle
112 N01a92b3881ef455fb74602736d32cf11 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Male
114 rdf:type schema:DefinedTerm
115 N07750c33c9294307b3b2681e26a2e7c0 rdf:first sg:person.01117726644.83
116 rdf:rest N99304eb103804718ad2e2ec048991dbe
117 N118ca7495f374d44b886e0c33f60da2e rdf:first sg:person.015436160633.43
118 rdf:rest N98340b6f0c73448c8d9c18f6535fc38a
119 N12b90891b965480eb78a47ad52a1c146 schema:issueNumber 10
120 rdf:type schema:PublicationIssue
121 N28dbc9a7562b45fabc7ac80422b0b224 rdf:first sg:person.0775745322.33
122 rdf:rest N2957754f9aa04467aca3c543ac16d10c
123 N2957754f9aa04467aca3c543ac16d10c rdf:first sg:person.01365155331.98
124 rdf:rest N07750c33c9294307b3b2681e26a2e7c0
125 N34bea93ce3db486a9407f968080b4734 rdf:first sg:person.01223410311.10
126 rdf:rest N28dbc9a7562b45fabc7ac80422b0b224
127 N369ac13130bd4a1493f28c55b09c9d16 schema:name doi
128 schema:value 10.1007/s00784-019-02804-4
129 rdf:type schema:PropertyValue
130 N3b5890c8b5094404ad788f00cbd8ce5c rdf:first sg:person.0620620701.31
131 rdf:rest N118ca7495f374d44b886e0c33f60da2e
132 N4e84840b7bcb42c6aca602666d03258b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Prognosis
134 rdf:type schema:DefinedTerm
135 N5655de101a034e98a26bc4b959ba8b36 rdf:first sg:person.01061545106.97
136 rdf:rest N34bea93ce3db486a9407f968080b4734
137 N5f5d411749d4459a8f99775c325cf219 schema:name Springer Nature - SN SciGraph project
138 rdf:type schema:Organization
139 N602c0c013f2c4f9f9d3ca5b2f1f6e715 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Carcinoma, Squamous Cell
141 rdf:type schema:DefinedTerm
142 N60b05417721f4c5e9757a1e7a49d769b schema:volumeNumber 23
143 rdf:type schema:PublicationVolume
144 N62f9f2e57623483ba88d5e6bad178e6c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Retrospective Studies
146 rdf:type schema:DefinedTerm
147 N7a467e0e3d544020a7a85722c2999118 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Neoplasm Recurrence, Local
149 rdf:type schema:DefinedTerm
150 N98340b6f0c73448c8d9c18f6535fc38a rdf:first sg:person.01365553214.04
151 rdf:rest N5655de101a034e98a26bc4b959ba8b36
152 N99304eb103804718ad2e2ec048991dbe rdf:first sg:person.01153154766.22
153 rdf:rest rdf:nil
154 Na1af0ed3e01646028d6ff8d4e9dfeb0e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Humans
156 rdf:type schema:DefinedTerm
157 Na4cd22c6bcb54a13a48f9f917b4d76f0 schema:name pubmed_id
158 schema:value 30673863
159 rdf:type schema:PropertyValue
160 Nb93ddf664b3b487c95cdea2709f256c3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Neoplasm Staging
162 rdf:type schema:DefinedTerm
163 Nc96a99e3c7db4b6197d0e65fd66401bf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Female
165 rdf:type schema:DefinedTerm
166 Nd1186e3896b1486d8d4ed93bca00627b schema:name dimensions_id
167 schema:value pub.1111634971
168 rdf:type schema:PropertyValue
169 Nf72acfb1bf834cb3be79108a54fc0aaf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Mouth Neoplasms
171 rdf:type schema:DefinedTerm
172 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
173 schema:name Medical and Health Sciences
174 rdf:type schema:DefinedTerm
175 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
176 schema:name Oncology and Carcinogenesis
177 rdf:type schema:DefinedTerm
178 sg:journal.1116831 schema:issn 1432-6981
179 1436-3771
180 schema:name Clinical Oral Investigations
181 schema:publisher Springer Nature
182 rdf:type schema:Periodical
183 sg:person.01061545106.97 schema:affiliation grid-institutes:grid.6190.e
184 schema:familyName Schick
185 schema:givenName Volker
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01061545106.97
187 rdf:type schema:Person
188 sg:person.01117726644.83 schema:affiliation grid-institutes:None
189 schema:familyName Zöller
190 schema:givenName Joachim E.
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117726644.83
192 rdf:type schema:Person
193 sg:person.01153154766.22 schema:affiliation grid-institutes:None
194 schema:familyName Kreppel
195 schema:givenName Matthias
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153154766.22
197 rdf:type schema:Person
198 sg:person.01223410311.10 schema:affiliation grid-institutes:grid.413225.3
199 schema:familyName Thiele
200 schema:givenName Oliver
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223410311.10
202 rdf:type schema:Person
203 sg:person.01365155331.98 schema:affiliation grid-institutes:None
204 schema:familyName Nickenig
205 schema:givenName Hans-Joachim
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365155331.98
207 rdf:type schema:Person
208 sg:person.01365553214.04 schema:affiliation grid-institutes:grid.6190.e
209 schema:familyName Drebber
210 schema:givenName Uta
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365553214.04
212 rdf:type schema:Person
213 sg:person.015436160633.43 schema:affiliation grid-institutes:None
214 schema:familyName Grochau
215 schema:givenName Kathrin
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015436160633.43
217 rdf:type schema:Person
218 sg:person.0620620701.31 schema:affiliation grid-institutes:None
219 schema:familyName Safi
220 schema:givenName Ali-Farid
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0620620701.31
222 rdf:type schema:Person
223 sg:person.0775745322.33 schema:affiliation grid-institutes:None
224 schema:familyName Backhaus
225 schema:givenName Tim
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775745322.33
227 rdf:type schema:Person
228 sg:pub.10.1007/s00428-010-0915-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024935977
229 https://doi.org/10.1007/s00428-010-0915-7
230 rdf:type schema:CreativeWork
231 sg:pub.10.1038/sj.bjc.6603152 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010492859
232 https://doi.org/10.1038/sj.bjc.6603152
233 rdf:type schema:CreativeWork
234 grid-institutes:None schema:alternateName Center for Integrated Oncology Cologne-Bonn, Cologne, Germany
235 schema:name Center for Integrated Oncology Cologne-Bonn, Cologne, Germany
236 Department for Oral and Craniomaxillofacial Plastic Surgery, University of Cologne, Kerpener Straße 62, 50931, Cologne, Germany
237 rdf:type schema:Organization
238 grid-institutes:grid.413225.3 schema:alternateName Department for Oral and Maxillofacial Plastic Surgery, Klinikum Ludwigshafen, Ludwigshafen, Germany
239 schema:name Department for Oral and Maxillofacial Plastic Surgery, Klinikum Ludwigshafen, Ludwigshafen, Germany
240 rdf:type schema:Organization
241 grid-institutes:grid.6190.e schema:alternateName Department for Anesthesiology and Intensive Care, University of Cologne, Cologne, Germany
242 Department for Pathology, University of Cologne, Cologne, Germany
243 schema:name Center for Integrated Oncology Cologne-Bonn, Cologne, Germany
244 Department for Anesthesiology and Intensive Care, University of Cologne, Cologne, Germany
245 Department for Pathology, University of Cologne, Cologne, Germany
246 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...