Analysis of heat-labile sites generated by reactions of depleted uranium and ascorbate in plasmid DNA View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-01

AUTHORS

Janice Wilson, Ashley Young, Edgar R. Civitello, Diane M. Stearns

ABSTRACT

The goal of this study was to characterize how depleted uranium (DU) causes DNA damage. Procedures were developed to assess the ability of organic and inorganic DNA adducts to convert to single-strand breaks (SSB) in pBR322 plasmid DNA in the presence of heat or piperidine. DNA adducts formed by methyl methanesulfonate, cisplatin, and chromic chloride were compared with those formed by reaction of uranyl acetate and ascorbate. Uranyl ion in the presence of ascorbate produced U-DNA adducts that converted to SSB on heating. Piperidine, which acted on DNA methylated by methyl methanesulfonate to convert methyl-DNA adducts to SSB, served in the opposite fashion as U-DNA adducts by decreasing the level of SSB. The observation that piperidine also decreased the gel shift for metal-DNA adducts formed by monofunctional cisplatin and chromic chloride was interpreted to suggest that piperidine served to remove U-DNA adducts. Radical scavengers did not affect the formation of uranium-induced SSB, suggesting that SSB arose from the presence of U-DNA adducts and not from the presence of free radicals. A model is proposed to predict how U-DNA adducts may serve as initial lesions that convert to SSB or AP sites. The results suggest that DU can act as a chemical genotoxin that does not require radiation for its mode of action. Characterizing the DNA lesions formed by DU is necessary to assess the relative importance of different DNA lesions in the formation of DU-induced mutations. Understanding the mechanisms of formation of DU-induced mutations may contribute to identification of biomarkers of DU exposure in humans. More... »

PAGES

45-57

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00775-013-1057-6

DOI

http://dx.doi.org/10.1007/s00775-013-1057-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046932718

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24218036


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ascorbic Acid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chlorides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromium Compounds", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA Damage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hot Temperature", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutagens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Organometallic Compounds", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plasmids", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Uranium", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Northern Arizona University", 
          "id": "https://www.grid.ac/institutes/grid.261120.6", 
          "name": [
            "Department of Chemistry and Biochemistry, Northern Arizona University, PO Box 5698, 86011-5698, Flagstaff, AZ, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wilson", 
        "givenName": "Janice", 
        "id": "sg:person.0772161130.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772161130.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Northern Arizona University", 
          "id": "https://www.grid.ac/institutes/grid.261120.6", 
          "name": [
            "Department of Chemistry and Biochemistry, Northern Arizona University, PO Box 5698, 86011-5698, Flagstaff, AZ, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Young", 
        "givenName": "Ashley", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Northern Arizona University", 
          "id": "https://www.grid.ac/institutes/grid.261120.6", 
          "name": [
            "Department of Chemistry and Biochemistry, Northern Arizona University, PO Box 5698, 86011-5698, Flagstaff, AZ, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Civitello", 
        "givenName": "Edgar R.", 
        "id": "sg:person.0605006700.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605006700.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Northern Arizona University", 
          "id": "https://www.grid.ac/institutes/grid.261120.6", 
          "name": [
            "Department of Chemistry and Biochemistry, Northern Arizona University, PO Box 5698, 86011-5698, Flagstaff, AZ, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stearns", 
        "givenName": "Diane M.", 
        "id": "sg:person.0601723636.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601723636.44"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/1752-1505-6-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000339442", 
          "https://doi.org/10.1186/1752-1505-6-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.78.4.2179", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003726378"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/ijerph7010303", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005722072"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.hp.0000298229.60229.10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007556021"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.hp.0000298229.60229.10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007556021"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.scitotenv.2010.08.028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007667419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.319.7207.401a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009160337"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0027-5107(83)90026-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010815654"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.bb.07.060178.001443", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011903448"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jtemb.2012.07.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012827776"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/10937400490452714", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013195100"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.10.3.335", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013370172"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(86)90088-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013844911"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(86)90088-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013844911"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/jom.0b013e31824fe138", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015914188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/jom.0b013e31824fe138", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015914188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1476-069x-8-29", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019204192", 
          "https://doi.org/10.1186/1476-069x-8-29"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/jom.0b013e31829176c7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019360049"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/jom.0b013e31829176c7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019360049"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0165-1218(93)90079-s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021777523"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0165-1218(93)90079-s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021777523"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mrgentox.2009.05.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022145758"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/19.11.2929", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022467083"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004032-200208000-00013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022701593"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004032-200208000-00013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022701593"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004032-200103000-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022790772"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004032-200103000-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022790772"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ccr.2005.09.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023201368"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envres.2011.01.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023275989"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mc.20155", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027430272"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mc.20155", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027430272"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/reveh.2007.22.1.75", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027606532"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/28.11.e51", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028997164"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m402486200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029154806"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/hp.0b013e3181cd6536", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030005916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/hp.0b013e3181cd6536", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030005916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/hp.0b013e3181cd6536", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030005916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1096-9888(199606)31:6<669::aid-jms340>3.0.co;2-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030457357"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0079-6603(08)60611-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031546530"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/jom.0b013e318042d682", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031981133"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/jom.0b013e318042d682", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031981133"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/18.13.3847", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032305899"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/13623699.2013.765173", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032893389"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0162-0134(02)00391-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034480211"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1099-1352(199605)9:3<219::aid-jmr242>3.0.co;2-s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037823488"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.icrp.2012.06.033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041725155"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.icrp.2012.06.033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041725155"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/mutage/gei056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043488469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/mutage/gei056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043488469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jenvrad.2008.12.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044089732"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004032-199407000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045527713"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004032-199407000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045527713"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/tx200251t", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048950019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/tx200251t", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048950019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/hp.0b013e3182243a7a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052196867"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/hp.0b013e3182243a7a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052196867"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.072067799", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052244565"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/em.20658", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052622203"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jenvrad.2012.08.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053032253"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.toxlet.2009.11.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053166558"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/20.21.5805", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053733578"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.hp.0000165450.76676.10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053737179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.hp.0000165450.76676.10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053737179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.hp.0000165450.76676.10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053737179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/cr60204a001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053943970"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00246a021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055166896"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00323a001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055170229"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00361a026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055172019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00377a039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055172832"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00843a022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055190596"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ic9013448", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055584814"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ic9013448", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055584814"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja00035a033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055700931"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja00039a003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055701261"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja00905a001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055756182"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja01028a024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055762468"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja01045a011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055763826"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja9625079", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055865730"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja9625079", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055865730"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/tx00038a016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056297011"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/tx025685q", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056297654"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/tx025685q", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056297654"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/tx034007g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056297696"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/tx034007g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056297696"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1269/jrr.07123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064613170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1289/ehp.98106465", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064746958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1667/rr2180.1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068195771"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2307/3578712", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070381201"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2307/3579271", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070381689"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078562691", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078596857", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-01", 
    "datePublishedReg": "2014-01-01", 
    "description": "The goal of this study was to characterize how depleted uranium (DU) causes DNA damage. Procedures were developed to assess the ability of organic and inorganic DNA adducts to convert to single-strand breaks (SSB) in pBR322 plasmid DNA in the presence of heat or piperidine. DNA adducts formed by methyl methanesulfonate, cisplatin, and chromic chloride were compared with those formed by reaction of uranyl acetate and ascorbate. Uranyl ion in the presence of ascorbate produced U-DNA adducts that converted to SSB on heating. Piperidine, which acted on DNA methylated by methyl methanesulfonate to convert methyl-DNA adducts to SSB, served in the opposite fashion as U-DNA adducts by decreasing the level of SSB. The observation that piperidine also decreased the gel shift for metal-DNA adducts formed by monofunctional cisplatin and chromic chloride was interpreted to suggest that piperidine served to remove U-DNA adducts. Radical scavengers did not affect the formation of uranium-induced SSB, suggesting that SSB arose from the presence of U-DNA adducts and not from the presence of free radicals. A model is proposed to predict how U-DNA adducts may serve as initial lesions that convert to SSB or AP sites. The results suggest that DU can act as a chemical genotoxin that does not require radiation for its mode of action. Characterizing the DNA lesions formed by DU is necessary to assess the relative importance of different DNA lesions in the formation of DU-induced mutations. Understanding the mechanisms of formation of DU-induced mutations may contribute to identification of biomarkers of DU exposure in humans. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00775-013-1057-6", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2699082", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2591752", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2623442", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1116242", 
        "issn": [
          "0949-8257", 
          "1432-1327"
        ], 
        "name": "JBIC Journal of Biological Inorganic Chemistry", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "19"
      }
    ], 
    "name": "Analysis of heat-labile sites generated by reactions of depleted uranium and ascorbate in plasmid DNA", 
    "pagination": "45-57", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "df9227eb4eab2cb64a75826df799a87af2953263f3950f3b8c3cf8266a721369"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "24218036"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9616326"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00775-013-1057-6"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1046932718"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00775-013-1057-6", 
      "https://app.dimensions.ai/details/publication/pub.1046932718"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T20:48", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8684_00000515.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00775-013-1057-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00775-013-1057-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00775-013-1057-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00775-013-1057-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00775-013-1057-6'


 

This table displays all metadata directly associated to this object as RDF triples.

346 TRIPLES      21 PREDICATES      109 URIs      32 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00775-013-1057-6 schema:about N08b2ea5ff9224e8f8f928cb8144bcee6
2 N0bf6d5b2889d4f1a834da9bbdcde3e3a
3 N1a2ef91e871e488fbe12539bc8f010da
4 N5fcffde924e747c587d21aa75ea820eb
5 N6212337f8576463b81a42c278c6edb10
6 N73548877417e46e4a0c3746fc21b9839
7 N74696d13ea2c490db2c1c8e1fce1de20
8 N9d1cb3bfcb3d4bc49b300c6c26b5fe41
9 Nbd4861d7274645b49daa1b395b68d970
10 Nc487ff0a9b5a4b43adc2acd8887f05cc
11 Nc607ea5b06d148278253a9360cbaf98f
12 anzsrc-for:06
13 anzsrc-for:0601
14 schema:author N53fa2ff83e684705b523c960e0875a65
15 schema:citation sg:pub.10.1186/1476-069x-8-29
16 sg:pub.10.1186/1752-1505-6-3
17 https://app.dimensions.ai/details/publication/pub.1078562691
18 https://app.dimensions.ai/details/publication/pub.1078596857
19 https://doi.org/10.1002/(sici)1096-9888(199606)31:6<669::aid-jms340>3.0.co;2-5
20 https://doi.org/10.1002/(sici)1099-1352(199605)9:3<219::aid-jmr242>3.0.co;2-s
21 https://doi.org/10.1002/em.20658
22 https://doi.org/10.1002/mc.20155
23 https://doi.org/10.1016/0027-5107(83)90026-x
24 https://doi.org/10.1016/0165-1218(93)90079-s
25 https://doi.org/10.1016/0167-4781(86)90088-6
26 https://doi.org/10.1016/j.ccr.2005.09.010
27 https://doi.org/10.1016/j.envres.2011.01.008
28 https://doi.org/10.1016/j.icrp.2012.06.033
29 https://doi.org/10.1016/j.jenvrad.2008.12.018
30 https://doi.org/10.1016/j.jenvrad.2012.08.009
31 https://doi.org/10.1016/j.jtemb.2012.07.004
32 https://doi.org/10.1016/j.mrgentox.2009.05.006
33 https://doi.org/10.1016/j.scitotenv.2010.08.028
34 https://doi.org/10.1016/j.toxlet.2009.11.009
35 https://doi.org/10.1016/s0079-6603(08)60611-x
36 https://doi.org/10.1016/s0162-0134(02)00391-4
37 https://doi.org/10.1021/bi00246a021
38 https://doi.org/10.1021/bi00323a001
39 https://doi.org/10.1021/bi00361a026
40 https://doi.org/10.1021/bi00377a039
41 https://doi.org/10.1021/bi00843a022
42 https://doi.org/10.1021/cr60204a001
43 https://doi.org/10.1021/ic9013448
44 https://doi.org/10.1021/ja00035a033
45 https://doi.org/10.1021/ja00039a003
46 https://doi.org/10.1021/ja00905a001
47 https://doi.org/10.1021/ja01028a024
48 https://doi.org/10.1021/ja01045a011
49 https://doi.org/10.1021/ja9625079
50 https://doi.org/10.1021/tx00038a016
51 https://doi.org/10.1021/tx025685q
52 https://doi.org/10.1021/tx034007g
53 https://doi.org/10.1021/tx200251t
54 https://doi.org/10.1073/pnas.072067799
55 https://doi.org/10.1073/pnas.78.4.2179
56 https://doi.org/10.1074/jbc.m402486200
57 https://doi.org/10.1080/10937400490452714
58 https://doi.org/10.1080/13623699.2013.765173
59 https://doi.org/10.1083/jcb.10.3.335
60 https://doi.org/10.1093/mutage/gei056
61 https://doi.org/10.1093/nar/18.13.3847
62 https://doi.org/10.1093/nar/19.11.2929
63 https://doi.org/10.1093/nar/20.21.5805
64 https://doi.org/10.1093/nar/28.11.e51
65 https://doi.org/10.1097/00004032-199407000-00001
66 https://doi.org/10.1097/00004032-200103000-00008
67 https://doi.org/10.1097/00004032-200208000-00013
68 https://doi.org/10.1097/01.hp.0000165450.76676.10
69 https://doi.org/10.1097/01.hp.0000298229.60229.10
70 https://doi.org/10.1097/hp.0b013e3181cd6536
71 https://doi.org/10.1097/hp.0b013e3182243a7a
72 https://doi.org/10.1097/jom.0b013e318042d682
73 https://doi.org/10.1097/jom.0b013e31824fe138
74 https://doi.org/10.1097/jom.0b013e31829176c7
75 https://doi.org/10.1136/bmj.319.7207.401a
76 https://doi.org/10.1146/annurev.bb.07.060178.001443
77 https://doi.org/10.1269/jrr.07123
78 https://doi.org/10.1289/ehp.98106465
79 https://doi.org/10.1515/reveh.2007.22.1.75
80 https://doi.org/10.1667/rr2180.1
81 https://doi.org/10.2307/3578712
82 https://doi.org/10.2307/3579271
83 https://doi.org/10.3390/ijerph7010303
84 schema:datePublished 2014-01
85 schema:datePublishedReg 2014-01-01
86 schema:description The goal of this study was to characterize how depleted uranium (DU) causes DNA damage. Procedures were developed to assess the ability of organic and inorganic DNA adducts to convert to single-strand breaks (SSB) in pBR322 plasmid DNA in the presence of heat or piperidine. DNA adducts formed by methyl methanesulfonate, cisplatin, and chromic chloride were compared with those formed by reaction of uranyl acetate and ascorbate. Uranyl ion in the presence of ascorbate produced U-DNA adducts that converted to SSB on heating. Piperidine, which acted on DNA methylated by methyl methanesulfonate to convert methyl-DNA adducts to SSB, served in the opposite fashion as U-DNA adducts by decreasing the level of SSB. The observation that piperidine also decreased the gel shift for metal-DNA adducts formed by monofunctional cisplatin and chromic chloride was interpreted to suggest that piperidine served to remove U-DNA adducts. Radical scavengers did not affect the formation of uranium-induced SSB, suggesting that SSB arose from the presence of U-DNA adducts and not from the presence of free radicals. A model is proposed to predict how U-DNA adducts may serve as initial lesions that convert to SSB or AP sites. The results suggest that DU can act as a chemical genotoxin that does not require radiation for its mode of action. Characterizing the DNA lesions formed by DU is necessary to assess the relative importance of different DNA lesions in the formation of DU-induced mutations. Understanding the mechanisms of formation of DU-induced mutations may contribute to identification of biomarkers of DU exposure in humans.
87 schema:genre research_article
88 schema:inLanguage en
89 schema:isAccessibleForFree true
90 schema:isPartOf N159fbb9827734f5ba4eb25bce30c5ac4
91 Nb9303d931a0a4ba98b3addac5b7fbd4b
92 sg:journal.1116242
93 schema:name Analysis of heat-labile sites generated by reactions of depleted uranium and ascorbate in plasmid DNA
94 schema:pagination 45-57
95 schema:productId N1de92722818c48f2b7e0b6cd40a3c7fd
96 N319657dd6ad64be1a86ac58841e56238
97 N81769f6c74634aa8aa27dcdd10811f52
98 Ndfef6771f59f410294a6d0dd50d04215
99 Nfeb46687d0714736a72a90bfba98ec51
100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046932718
101 https://doi.org/10.1007/s00775-013-1057-6
102 schema:sdDatePublished 2019-04-10T20:48
103 schema:sdLicense https://scigraph.springernature.com/explorer/license/
104 schema:sdPublisher N6643aee8f9ed4bc1ad88616df245598f
105 schema:url http://link.springer.com/10.1007%2Fs00775-013-1057-6
106 sgo:license sg:explorer/license/
107 sgo:sdDataset articles
108 rdf:type schema:ScholarlyArticle
109 N001f57015ea249d29038d926dec67e33 schema:affiliation https://www.grid.ac/institutes/grid.261120.6
110 schema:familyName Young
111 schema:givenName Ashley
112 rdf:type schema:Person
113 N08b2ea5ff9224e8f8f928cb8144bcee6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Organometallic Compounds
115 rdf:type schema:DefinedTerm
116 N0bf6d5b2889d4f1a834da9bbdcde3e3a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Mutagens
118 rdf:type schema:DefinedTerm
119 N159fbb9827734f5ba4eb25bce30c5ac4 schema:volumeNumber 19
120 rdf:type schema:PublicationVolume
121 N1a2ef91e871e488fbe12539bc8f010da schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name DNA Damage
123 rdf:type schema:DefinedTerm
124 N1de92722818c48f2b7e0b6cd40a3c7fd schema:name nlm_unique_id
125 schema:value 9616326
126 rdf:type schema:PropertyValue
127 N319657dd6ad64be1a86ac58841e56238 schema:name readcube_id
128 schema:value df9227eb4eab2cb64a75826df799a87af2953263f3950f3b8c3cf8266a721369
129 rdf:type schema:PropertyValue
130 N53fa2ff83e684705b523c960e0875a65 rdf:first sg:person.0772161130.02
131 rdf:rest Nd39f95a7514a4d3cbe815bb1ea72e760
132 N5fcffde924e747c587d21aa75ea820eb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Ascorbic Acid
134 rdf:type schema:DefinedTerm
135 N6212337f8576463b81a42c278c6edb10 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Chromium Compounds
137 rdf:type schema:DefinedTerm
138 N6643aee8f9ed4bc1ad88616df245598f schema:name Springer Nature - SN SciGraph project
139 rdf:type schema:Organization
140 N73548877417e46e4a0c3746fc21b9839 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Plasmids
142 rdf:type schema:DefinedTerm
143 N74696d13ea2c490db2c1c8e1fce1de20 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Hot Temperature
145 rdf:type schema:DefinedTerm
146 N81769f6c74634aa8aa27dcdd10811f52 schema:name dimensions_id
147 schema:value pub.1046932718
148 rdf:type schema:PropertyValue
149 N9b6a216aec124a478857c65516273e21 rdf:first sg:person.0605006700.86
150 rdf:rest Nfb6f985ae09649fcb385b26baf2ba296
151 N9d1cb3bfcb3d4bc49b300c6c26b5fe41 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Humans
153 rdf:type schema:DefinedTerm
154 Nb9303d931a0a4ba98b3addac5b7fbd4b schema:issueNumber 1
155 rdf:type schema:PublicationIssue
156 Nbd4861d7274645b49daa1b395b68d970 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Chlorides
158 rdf:type schema:DefinedTerm
159 Nc487ff0a9b5a4b43adc2acd8887f05cc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Uranium
161 rdf:type schema:DefinedTerm
162 Nc607ea5b06d148278253a9360cbaf98f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name DNA
164 rdf:type schema:DefinedTerm
165 Nd39f95a7514a4d3cbe815bb1ea72e760 rdf:first N001f57015ea249d29038d926dec67e33
166 rdf:rest N9b6a216aec124a478857c65516273e21
167 Ndfef6771f59f410294a6d0dd50d04215 schema:name pubmed_id
168 schema:value 24218036
169 rdf:type schema:PropertyValue
170 Nfb6f985ae09649fcb385b26baf2ba296 rdf:first sg:person.0601723636.44
171 rdf:rest rdf:nil
172 Nfeb46687d0714736a72a90bfba98ec51 schema:name doi
173 schema:value 10.1007/s00775-013-1057-6
174 rdf:type schema:PropertyValue
175 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
176 schema:name Biological Sciences
177 rdf:type schema:DefinedTerm
178 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
179 schema:name Biochemistry and Cell Biology
180 rdf:type schema:DefinedTerm
181 sg:grant.2591752 http://pending.schema.org/fundedItem sg:pub.10.1007/s00775-013-1057-6
182 rdf:type schema:MonetaryGrant
183 sg:grant.2623442 http://pending.schema.org/fundedItem sg:pub.10.1007/s00775-013-1057-6
184 rdf:type schema:MonetaryGrant
185 sg:grant.2699082 http://pending.schema.org/fundedItem sg:pub.10.1007/s00775-013-1057-6
186 rdf:type schema:MonetaryGrant
187 sg:journal.1116242 schema:issn 0949-8257
188 1432-1327
189 schema:name JBIC Journal of Biological Inorganic Chemistry
190 rdf:type schema:Periodical
191 sg:person.0601723636.44 schema:affiliation https://www.grid.ac/institutes/grid.261120.6
192 schema:familyName Stearns
193 schema:givenName Diane M.
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601723636.44
195 rdf:type schema:Person
196 sg:person.0605006700.86 schema:affiliation https://www.grid.ac/institutes/grid.261120.6
197 schema:familyName Civitello
198 schema:givenName Edgar R.
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605006700.86
200 rdf:type schema:Person
201 sg:person.0772161130.02 schema:affiliation https://www.grid.ac/institutes/grid.261120.6
202 schema:familyName Wilson
203 schema:givenName Janice
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772161130.02
205 rdf:type schema:Person
206 sg:pub.10.1186/1476-069x-8-29 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019204192
207 https://doi.org/10.1186/1476-069x-8-29
208 rdf:type schema:CreativeWork
209 sg:pub.10.1186/1752-1505-6-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000339442
210 https://doi.org/10.1186/1752-1505-6-3
211 rdf:type schema:CreativeWork
212 https://app.dimensions.ai/details/publication/pub.1078562691 schema:CreativeWork
213 https://app.dimensions.ai/details/publication/pub.1078596857 schema:CreativeWork
214 https://doi.org/10.1002/(sici)1096-9888(199606)31:6<669::aid-jms340>3.0.co;2-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030457357
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1002/(sici)1099-1352(199605)9:3<219::aid-jmr242>3.0.co;2-s schema:sameAs https://app.dimensions.ai/details/publication/pub.1037823488
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1002/em.20658 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052622203
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1002/mc.20155 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027430272
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1016/0027-5107(83)90026-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1010815654
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1016/0165-1218(93)90079-s schema:sameAs https://app.dimensions.ai/details/publication/pub.1021777523
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1016/0167-4781(86)90088-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013844911
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1016/j.ccr.2005.09.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023201368
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1016/j.envres.2011.01.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023275989
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1016/j.icrp.2012.06.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041725155
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1016/j.jenvrad.2008.12.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044089732
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1016/j.jenvrad.2012.08.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053032253
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1016/j.jtemb.2012.07.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012827776
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1016/j.mrgentox.2009.05.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022145758
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1016/j.scitotenv.2010.08.028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007667419
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1016/j.toxlet.2009.11.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053166558
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1016/s0079-6603(08)60611-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1031546530
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1016/s0162-0134(02)00391-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034480211
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1021/bi00246a021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055166896
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1021/bi00323a001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055170229
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1021/bi00361a026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055172019
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1021/bi00377a039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055172832
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1021/bi00843a022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055190596
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1021/cr60204a001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053943970
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1021/ic9013448 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055584814
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1021/ja00035a033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055700931
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1021/ja00039a003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055701261
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1021/ja00905a001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055756182
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1021/ja01028a024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055762468
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1021/ja01045a011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055763826
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1021/ja9625079 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055865730
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1021/tx00038a016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056297011
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1021/tx025685q schema:sameAs https://app.dimensions.ai/details/publication/pub.1056297654
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1021/tx034007g schema:sameAs https://app.dimensions.ai/details/publication/pub.1056297696
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1021/tx200251t schema:sameAs https://app.dimensions.ai/details/publication/pub.1048950019
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1073/pnas.072067799 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052244565
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1073/pnas.78.4.2179 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003726378
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1074/jbc.m402486200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029154806
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1080/10937400490452714 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013195100
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1080/13623699.2013.765173 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032893389
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1083/jcb.10.3.335 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013370172
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1093/mutage/gei056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043488469
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1093/nar/18.13.3847 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032305899
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1093/nar/19.11.2929 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022467083
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1093/nar/20.21.5805 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053733578
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1093/nar/28.11.e51 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028997164
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1097/00004032-199407000-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045527713
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1097/00004032-200103000-00008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022790772
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1097/00004032-200208000-00013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022701593
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1097/01.hp.0000165450.76676.10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053737179
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1097/01.hp.0000298229.60229.10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007556021
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1097/hp.0b013e3181cd6536 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030005916
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1097/hp.0b013e3182243a7a schema:sameAs https://app.dimensions.ai/details/publication/pub.1052196867
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1097/jom.0b013e318042d682 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031981133
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1097/jom.0b013e31824fe138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015914188
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1097/jom.0b013e31829176c7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019360049
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1136/bmj.319.7207.401a schema:sameAs https://app.dimensions.ai/details/publication/pub.1009160337
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1146/annurev.bb.07.060178.001443 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011903448
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1269/jrr.07123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064613170
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1289/ehp.98106465 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064746958
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1515/reveh.2007.22.1.75 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027606532
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1667/rr2180.1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068195771
337 rdf:type schema:CreativeWork
338 https://doi.org/10.2307/3578712 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070381201
339 rdf:type schema:CreativeWork
340 https://doi.org/10.2307/3579271 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070381689
341 rdf:type schema:CreativeWork
342 https://doi.org/10.3390/ijerph7010303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005722072
343 rdf:type schema:CreativeWork
344 https://www.grid.ac/institutes/grid.261120.6 schema:alternateName Northern Arizona University
345 schema:name Department of Chemistry and Biochemistry, Northern Arizona University, PO Box 5698, 86011-5698, Flagstaff, AZ, USA
346 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...