Evaluating spine micro-architectural texture (via TBS) discriminates major osteoporotic fractures from controls both as well as and independent of site ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-09

AUTHORS

Jelena Vasic, Tzvetanka Petranova, Vladyslav Povoroznyuk, Carmen Gabriela Barbu, Mirjana Karadzic, Filip Gojkovic, Jelena Elez, Renaud Winzenrieth, Didier Hans, Violeta CulaficVojinovic, Catalina Poiana, Nataliia Dzerovych, Rasho Rashkov, Aleksandar Dimic

ABSTRACT

The aim of the study was to assess the clinical performance of the model combining areal bone mineral density (aBMD) at spine and microarchitecural texture (TBS) for the detection of the osteoporotic fracture. The Eastern European Study is a multicenter study (Serbia, Bulgaria, Romania and Ukraine) evaluating the role of TBS in routine clinical practice as a complement to aBMD. All scans were acquired on Hologic Discovery and GE Prodigy densitometers in a routine clinical manner. The additional clinical values of aBMD and TBS were analyzed using a two steps classification tree approach (aBMD followed by TBS tertiles) for all type of osteoporotic fracture (All-OP Fx). Sensitivity, specificity and accuracy of fracture detection as well as the Net Reclassification Index (NRI) were calculated. This study involves 1031 women subjects aged 45 and older recruited in east European countries. Clinical centers were cross-calibrated in terms of BMD and TBS. As expected, areal BMD (aBMD) at spine and TBS were only moderately correlated (r (2) = 0.19). Prevalence rate for All-OP Fx was 26 %. Subjects with fracture have significant lower TBS and aBMD than subjects without fracture (p < 0.01). TBS remains associated with the fracture even after adjustment for age and aBMD with an OR of 1.27 [1.07-1.51]. When using aBMD T-score of -2.5 and the lowest TBS tertile thresholds, both BMD and TBS were similar in terms of sensitivity (35 vs. 39 %), specificity (78 vs. 80 %) and accuracy (64 vs. 66 %). aBMD and TBS combination, induced a significant improvement in sensitivity (+28 %) and accuracy (+17 %) compared to aBMD alone whereas a moderate improvement was observed in terms of specificity (+9 %). The overall combination gain was 36 % as expressed using the NRI. aBMD and TBS combination decrease significantly the number of subjects needed to diagnose from 7 for aBMD alone to 2. In a multi-centre Eastern European cohort, we have shown that the use of TBS in addition to the aBMD permit to reclassified correctly more than one-third of the overall subjects. Furthermore, the number of subjects needed to diagnose fell to 2 subjects. Economical studies have to be performed to evaluate the gain induced by the use of TBS for the healthcare system. More... »

PAGES

556-562

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00774-013-0529-7

DOI

http://dx.doi.org/10.1007/s00774-013-0529-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1004953359

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24196870


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anthropometry", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Area Under Curve", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone Density", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Case-Control Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Europe, Eastern", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Multivariate Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Odds Ratio", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Osteoporotic Fractures", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "ROC Curve", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Radiography", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sensitivity and Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Spine", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Department of Physical Medicine and Rehabilitation, Railway Healthcare Center, Belgrade, Serbia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vasic", 
        "givenName": "Jelena", 
        "id": "sg:person.01166456174.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01166456174.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medical University of Sofia", 
          "id": "https://www.grid.ac/institutes/grid.410563.5", 
          "name": [
            "Clinic of Rheumatology, Medical University, Sofia, Bulgaria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Petranova", 
        "givenName": "Tzvetanka", 
        "id": "sg:person.01106336063.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106336063.60"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Academy of Medical Sciences of Ukraine", 
          "id": "https://www.grid.ac/institutes/grid.419973.1", 
          "name": [
            "Department of Clinical Physiology and Pathology of Locomotor Apparatus, D.F. Chebotarev Institute of Gerontology NAMS Ukraine and Ukrainian Scientific-Medical Center for the Problems of Osteoporosis, Kiev, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Povoroznyuk", 
        "givenName": "Vladyslav", 
        "id": "sg:person.012065244037.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012065244037.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Carol Davila University of Medicine and Pharmacy", 
          "id": "https://www.grid.ac/institutes/grid.8194.4", 
          "name": [
            "Department of Endocrinology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Barbu", 
        "givenName": "Carmen Gabriela", 
        "id": "sg:person.01222601175.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222601175.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Institute for Treatment and Rehabilitation \u201cNiska Banja\u201d, Nis, Serbia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Karadzic", 
        "givenName": "Mirjana", 
        "id": "sg:person.0625413674.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625413674.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Physical Medicine and Rehabilitation, Railway Healthcare Center, Belgrade, Serbia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gojkovic", 
        "givenName": "Filip", 
        "id": "sg:person.0673527074.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673527074.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Internal Medicine, Railway Healthcare Center, Belgrade, Serbia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Elez", 
        "givenName": "Jelena", 
        "id": "sg:person.0741642274.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741642274.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Xavier Arnozan", 
          "id": "https://www.grid.ac/institutes/grid.414477.5", 
          "name": [
            "R&D Department, Med-Imaps, PTIB, Hopital Xavier Arnozan, Avenue du Haut-L\u00e9v\u00eaque, 33600, Pessac, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Winzenrieth", 
        "givenName": "Renaud", 
        "id": "sg:person.0712753573.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0712753573.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital of Lausanne", 
          "id": "https://www.grid.ac/institutes/grid.8515.9", 
          "name": [
            "Bone Diseases Center, DAL, Lausanne University Hospital, Lausanne, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hans", 
        "givenName": "Didier", 
        "id": "sg:person.01144543125.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01144543125.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Internal Medicine, Railway Healthcare Center, Belgrade, Serbia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "CulaficVojinovic", 
        "givenName": "Violeta", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Carol Davila University of Medicine and Pharmacy", 
          "id": "https://www.grid.ac/institutes/grid.8194.4", 
          "name": [
            "Department of Endocrinology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Poiana", 
        "givenName": "Catalina", 
        "id": "sg:person.01061641462.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01061641462.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Academy of Medical Sciences of Ukraine", 
          "id": "https://www.grid.ac/institutes/grid.419973.1", 
          "name": [
            "Department of Clinical Physiology and Pathology of Locomotor Apparatus, D.F. Chebotarev Institute of Gerontology NAMS Ukraine and Ukrainian Scientific-Medical Center for the Problems of Osteoporosis, Kiev, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dzerovych", 
        "givenName": "Nataliia", 
        "id": "sg:person.012231563115.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012231563115.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medical University of Sofia", 
          "id": "https://www.grid.ac/institutes/grid.410563.5", 
          "name": [
            "Clinic of Rheumatology, Medical University, Sofia, Bulgaria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rashkov", 
        "givenName": "Rasho", 
        "id": "sg:person.0616335654.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0616335654.92"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Institute for Treatment and Rehabilitation \u201cNiska Banja\u201d, Nis, Serbia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dimic", 
        "givenName": "Aleksandar", 
        "id": "sg:person.0612751202.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0612751202.48"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1056/nejmra053077", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000793776"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jocd.2012.05.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003129571"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bone.2012.11.041", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003743624"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jocd.2013.05.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005011764"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00198-013-2316-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006849290", 
          "https://doi.org/10.1007/s00198-013-2316-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jocd.2012.01.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007409975"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0021-9290(88)90008-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011397653"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s8756-3282(00)00329-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015677715"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00223-009-9322-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022165572", 
          "https://doi.org/10.1007/s00223-009-9322-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00223-009-9322-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022165572", 
          "https://doi.org/10.1007/s00223-009-9322-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00223-009-9322-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022165572", 
          "https://doi.org/10.1007/s00223-009-9322-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(1950)3:1<32::aid-cncr2820030106>3.0.co;2-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024768178"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bone.2005.11.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025281992"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jbmr.499", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030492867"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00198-009-1062-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033192394", 
          "https://doi.org/10.1007/s00198-009-1062-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00198-009-1062-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033192394", 
          "https://doi.org/10.1007/s00198-009-1062-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00198-009-1062-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033192394", 
          "https://doi.org/10.1007/s00198-009-1062-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jbmr.1648", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033341246"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1359/jbmr.050610", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035905222"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00198-015-3078-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037778668", 
          "https://doi.org/10.1007/s00198-015-3078-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jocd.2011.05.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041135489"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1359/jbmr.050304", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042450609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/sim.2929", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044960408"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jocd.2012.08.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047306045"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.berh.2009.09.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048032412"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00198-012-2188-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049147904", 
          "https://doi.org/10.1007/s00198-012-2188-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00198-012-2008-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049829868", 
          "https://doi.org/10.1007/s00198-012-2008-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078492370", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082575724", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-09", 
    "datePublishedReg": "2014-09-01", 
    "description": "The aim of the study was to assess the clinical performance of the model combining areal bone mineral density (aBMD) at spine and microarchitecural texture (TBS) for the detection of the osteoporotic fracture. The Eastern European Study is a multicenter study (Serbia, Bulgaria, Romania and Ukraine) evaluating the role of TBS in routine clinical practice as a complement to aBMD. All scans were acquired on Hologic Discovery and GE Prodigy densitometers in a routine clinical manner. The additional clinical values of aBMD and TBS were analyzed using a two steps classification tree approach (aBMD followed by TBS tertiles) for all type of osteoporotic fracture (All-OP Fx). Sensitivity, specificity and accuracy of fracture detection as well as the Net Reclassification Index (NRI) were calculated. This study involves 1031 women subjects aged 45 and older recruited in east European countries. Clinical centers were cross-calibrated in terms of BMD and TBS. As expected, areal BMD (aBMD) at spine and TBS were only moderately correlated (r (2) = 0.19). Prevalence rate for All-OP Fx was 26 %. Subjects with fracture have significant lower TBS and aBMD than subjects without fracture (p < 0.01). TBS remains associated with the fracture even after adjustment for age and aBMD with an OR of 1.27 [1.07-1.51]. When using aBMD T-score of -2.5 and the lowest TBS tertile thresholds, both BMD and TBS were similar in terms of sensitivity (35 vs. 39 %), specificity (78 vs. 80 %) and accuracy (64 vs. 66 %). aBMD and TBS combination, induced a significant improvement in sensitivity (+28 %) and accuracy (+17 %) compared to aBMD alone whereas a moderate improvement was observed in terms of specificity (+9 %). The overall combination gain was 36 % as expressed using the NRI. aBMD and TBS combination decrease significantly the number of subjects needed to diagnose from 7 for aBMD alone to 2. In a multi-centre Eastern European cohort, we have shown that the use of TBS in addition to the aBMD permit to reclassified correctly more than one-third of the overall subjects. Furthermore, the number of subjects needed to diagnose fell to 2 subjects. Economical studies have to be performed to evaluate the gain induced by the use of TBS for the healthcare system.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00774-013-0529-7", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1312216", 
        "issn": [
          "0914-8779", 
          "1435-5604"
        ], 
        "name": "Journal of Bone and Mineral Metabolism", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "32"
      }
    ], 
    "name": "Evaluating spine micro-architectural texture (via TBS) discriminates major osteoporotic fractures from controls both as well as and independent of site matched BMD: the Eastern European TBS study", 
    "pagination": "556-562", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "179aa16f8a20c012409d88327faecc05614fff94e22685576c3b2c638d203560"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "24196870"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9436705"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00774-013-0529-7"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1004953359"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00774-013-0529-7", 
      "https://app.dimensions.ai/details/publication/pub.1004953359"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T22:31", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8690_00000510.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00774-013-0529-7"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00774-013-0529-7'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00774-013-0529-7'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00774-013-0529-7'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00774-013-0529-7'


 

This table displays all metadata directly associated to this object as RDF triples.

326 TRIPLES      21 PREDICATES      70 URIs      37 LITERALS      25 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00774-013-0529-7 schema:about N10d743df20424bebb3cab5ebd79c9009
2 N127e77533f5d4d8b8bd7f088a5f3fe11
3 N2b3cbe4864d14bcebb5cff2f971ef6db
4 N30a802be222d4ffd983f5db760055b06
5 N55f55539d9fb4f03aa87afb1f5e5bacc
6 N5e5dce9b9d2244258763bb1d290c3e83
7 N70426cae3b4d4f9790e0dbfe685a7bb2
8 N7350c02f187046e6a0c3316f6b5c629d
9 N7afe6c1687be4dc4bbf5bb0dee8c83ed
10 N7f10fd683e04476e91efffd5751621f8
11 N999d9dc0f7b94de89c6e6467103ec435
12 Na71680645f104da4ac80fd035129ae1b
13 Nb8ea8de9318e4888994e3aa7f4b8e0c5
14 Ndf473250240d4368831c5486586e8f9f
15 Ne24a4a56e391478ab335612c671f721d
16 Nfdc533e0d0ef40f3979fae032a203d60
17 anzsrc-for:11
18 anzsrc-for:1103
19 schema:author N34540b45e5394f94a2ceb30ff4fa106a
20 schema:citation sg:pub.10.1007/s00198-009-1062-3
21 sg:pub.10.1007/s00198-012-2008-8
22 sg:pub.10.1007/s00198-012-2188-2
23 sg:pub.10.1007/s00198-013-2316-7
24 sg:pub.10.1007/s00198-015-3078-1
25 sg:pub.10.1007/s00223-009-9322-y
26 https://app.dimensions.ai/details/publication/pub.1078492370
27 https://app.dimensions.ai/details/publication/pub.1082575724
28 https://doi.org/10.1002/1097-0142(1950)3:1<32::aid-cncr2820030106>3.0.co;2-3
29 https://doi.org/10.1002/jbmr.1648
30 https://doi.org/10.1002/jbmr.499
31 https://doi.org/10.1002/sim.2929
32 https://doi.org/10.1016/0021-9290(88)90008-5
33 https://doi.org/10.1016/j.berh.2009.09.007
34 https://doi.org/10.1016/j.bone.2005.11.012
35 https://doi.org/10.1016/j.bone.2012.11.041
36 https://doi.org/10.1016/j.jocd.2011.05.005
37 https://doi.org/10.1016/j.jocd.2012.01.007
38 https://doi.org/10.1016/j.jocd.2012.05.001
39 https://doi.org/10.1016/j.jocd.2012.08.011
40 https://doi.org/10.1016/j.jocd.2013.05.022
41 https://doi.org/10.1016/s8756-3282(00)00329-x
42 https://doi.org/10.1056/nejmra053077
43 https://doi.org/10.1359/jbmr.050304
44 https://doi.org/10.1359/jbmr.050610
45 schema:datePublished 2014-09
46 schema:datePublishedReg 2014-09-01
47 schema:description The aim of the study was to assess the clinical performance of the model combining areal bone mineral density (aBMD) at spine and microarchitecural texture (TBS) for the detection of the osteoporotic fracture. The Eastern European Study is a multicenter study (Serbia, Bulgaria, Romania and Ukraine) evaluating the role of TBS in routine clinical practice as a complement to aBMD. All scans were acquired on Hologic Discovery and GE Prodigy densitometers in a routine clinical manner. The additional clinical values of aBMD and TBS were analyzed using a two steps classification tree approach (aBMD followed by TBS tertiles) for all type of osteoporotic fracture (All-OP Fx). Sensitivity, specificity and accuracy of fracture detection as well as the Net Reclassification Index (NRI) were calculated. This study involves 1031 women subjects aged 45 and older recruited in east European countries. Clinical centers were cross-calibrated in terms of BMD and TBS. As expected, areal BMD (aBMD) at spine and TBS were only moderately correlated (r (2) = 0.19). Prevalence rate for All-OP Fx was 26 %. Subjects with fracture have significant lower TBS and aBMD than subjects without fracture (p < 0.01). TBS remains associated with the fracture even after adjustment for age and aBMD with an OR of 1.27 [1.07-1.51]. When using aBMD T-score of -2.5 and the lowest TBS tertile thresholds, both BMD and TBS were similar in terms of sensitivity (35 vs. 39 %), specificity (78 vs. 80 %) and accuracy (64 vs. 66 %). aBMD and TBS combination, induced a significant improvement in sensitivity (+28 %) and accuracy (+17 %) compared to aBMD alone whereas a moderate improvement was observed in terms of specificity (+9 %). The overall combination gain was 36 % as expressed using the NRI. aBMD and TBS combination decrease significantly the number of subjects needed to diagnose from 7 for aBMD alone to 2. In a multi-centre Eastern European cohort, we have shown that the use of TBS in addition to the aBMD permit to reclassified correctly more than one-third of the overall subjects. Furthermore, the number of subjects needed to diagnose fell to 2 subjects. Economical studies have to be performed to evaluate the gain induced by the use of TBS for the healthcare system.
48 schema:genre research_article
49 schema:inLanguage en
50 schema:isAccessibleForFree false
51 schema:isPartOf N2530e9a551ad47bb9ebff4a355ee8aae
52 N86b7265249784bf4a95615a5aa7cf507
53 sg:journal.1312216
54 schema:name Evaluating spine micro-architectural texture (via TBS) discriminates major osteoporotic fractures from controls both as well as and independent of site matched BMD: the Eastern European TBS study
55 schema:pagination 556-562
56 schema:productId N1e496c8ea00c47baa5f7c36a9f3d57f9
57 N537631c777354ba0a40fe8cdeda5ebc6
58 N5574d86dca7d4171adc368984b06146b
59 Nd632eff535384fadac0d83d3175d8458
60 Ne92270a6a76e4983bfa6b4dd9076b79c
61 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004953359
62 https://doi.org/10.1007/s00774-013-0529-7
63 schema:sdDatePublished 2019-04-10T22:31
64 schema:sdLicense https://scigraph.springernature.com/explorer/license/
65 schema:sdPublisher N9e40a3341fef4f86a85120fba7d76c68
66 schema:url http://link.springer.com/10.1007%2Fs00774-013-0529-7
67 sgo:license sg:explorer/license/
68 sgo:sdDataset articles
69 rdf:type schema:ScholarlyArticle
70 N08e474e902ab470890f1ac70b2749bdd schema:name Department of Physical Medicine and Rehabilitation, Railway Healthcare Center, Belgrade, Serbia
71 rdf:type schema:Organization
72 N0d28759047de4af98a20daf874810299 schema:name Department of Internal Medicine, Railway Healthcare Center, Belgrade, Serbia
73 rdf:type schema:Organization
74 N10d743df20424bebb3cab5ebd79c9009 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Odds Ratio
76 rdf:type schema:DefinedTerm
77 N127e77533f5d4d8b8bd7f088a5f3fe11 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Humans
79 rdf:type schema:DefinedTerm
80 N12a0b2f993d74ee9a53835c4bdf17007 rdf:first sg:person.0673527074.07
81 rdf:rest N8c2709ff36e64cb0b70b2cd747744b27
82 N1e496c8ea00c47baa5f7c36a9f3d57f9 schema:name doi
83 schema:value 10.1007/s00774-013-0529-7
84 rdf:type schema:PropertyValue
85 N24beb643695e4f65a52f50c036c57f7a rdf:first sg:person.0712753573.30
86 rdf:rest N395154ae377a48d9b666136c37a2d05e
87 N2530e9a551ad47bb9ebff4a355ee8aae schema:issueNumber 5
88 rdf:type schema:PublicationIssue
89 N2b3cbe4864d14bcebb5cff2f971ef6db schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Radiography
91 rdf:type schema:DefinedTerm
92 N2e18200b47394fa490cdf144c347ab9f rdf:first sg:person.0612751202.48
93 rdf:rest rdf:nil
94 N30a802be222d4ffd983f5db760055b06 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Anthropometry
96 rdf:type schema:DefinedTerm
97 N30c180ef5aac409b8fd274443812eaf4 rdf:first Neddae1d69f014f919d0a38dd631a7ac9
98 rdf:rest N857737a16769413091ed2cf4ed03da96
99 N34540b45e5394f94a2ceb30ff4fa106a rdf:first sg:person.01166456174.94
100 rdf:rest N589f4a93db13470397204dac9830eb4f
101 N395154ae377a48d9b666136c37a2d05e rdf:first sg:person.01144543125.50
102 rdf:rest N30c180ef5aac409b8fd274443812eaf4
103 N3c22419d8a5043499d7e8d95004a0d26 rdf:first sg:person.012065244037.40
104 rdf:rest Ne4a74aa45bff42e7af0ea876912042fb
105 N434805a326a94aabb8a90500e600749c rdf:first sg:person.012231563115.71
106 rdf:rest N812ed8f497bd44a584f85b9a0789d904
107 N537631c777354ba0a40fe8cdeda5ebc6 schema:name dimensions_id
108 schema:value pub.1004953359
109 rdf:type schema:PropertyValue
110 N5574d86dca7d4171adc368984b06146b schema:name readcube_id
111 schema:value 179aa16f8a20c012409d88327faecc05614fff94e22685576c3b2c638d203560
112 rdf:type schema:PropertyValue
113 N55f55539d9fb4f03aa87afb1f5e5bacc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Aged
115 rdf:type schema:DefinedTerm
116 N5751c80d1f584d7d8f42c44fa5106047 schema:name Institute for Treatment and Rehabilitation “Niska Banja”, Nis, Serbia
117 rdf:type schema:Organization
118 N589f4a93db13470397204dac9830eb4f rdf:first sg:person.01106336063.60
119 rdf:rest N3c22419d8a5043499d7e8d95004a0d26
120 N5e5dce9b9d2244258763bb1d290c3e83 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name ROC Curve
122 rdf:type schema:DefinedTerm
123 N70426cae3b4d4f9790e0dbfe685a7bb2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Middle Aged
125 rdf:type schema:DefinedTerm
126 N7350c02f187046e6a0c3316f6b5c629d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Area Under Curve
128 rdf:type schema:DefinedTerm
129 N7afe6c1687be4dc4bbf5bb0dee8c83ed schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Osteoporotic Fractures
131 rdf:type schema:DefinedTerm
132 N7f10fd683e04476e91efffd5751621f8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Sensitivity and Specificity
134 rdf:type schema:DefinedTerm
135 N812ed8f497bd44a584f85b9a0789d904 rdf:first sg:person.0616335654.92
136 rdf:rest N2e18200b47394fa490cdf144c347ab9f
137 N857737a16769413091ed2cf4ed03da96 rdf:first sg:person.01061641462.43
138 rdf:rest N434805a326a94aabb8a90500e600749c
139 N86b7265249784bf4a95615a5aa7cf507 schema:volumeNumber 32
140 rdf:type schema:PublicationVolume
141 N8c2709ff36e64cb0b70b2cd747744b27 rdf:first sg:person.0741642274.15
142 rdf:rest N24beb643695e4f65a52f50c036c57f7a
143 N90e20b9eed24413388547c18f026514e schema:name Department of Internal Medicine, Railway Healthcare Center, Belgrade, Serbia
144 rdf:type schema:Organization
145 N999d9dc0f7b94de89c6e6467103ec435 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Europe, Eastern
147 rdf:type schema:DefinedTerm
148 N9c77313b65da4002a86c2ecd94d8c94f schema:name Department of Physical Medicine and Rehabilitation, Railway Healthcare Center, Belgrade, Serbia
149 rdf:type schema:Organization
150 N9e40a3341fef4f86a85120fba7d76c68 schema:name Springer Nature - SN SciGraph project
151 rdf:type schema:Organization
152 Na71680645f104da4ac80fd035129ae1b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Female
154 rdf:type schema:DefinedTerm
155 Nb8ea8de9318e4888994e3aa7f4b8e0c5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Bone Density
157 rdf:type schema:DefinedTerm
158 Nd632eff535384fadac0d83d3175d8458 schema:name nlm_unique_id
159 schema:value 9436705
160 rdf:type schema:PropertyValue
161 Nda05b7f9bd334cd2975834be9ca93288 rdf:first sg:person.0625413674.15
162 rdf:rest N12a0b2f993d74ee9a53835c4bdf17007
163 Ndf473250240d4368831c5486586e8f9f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Case-Control Studies
165 rdf:type schema:DefinedTerm
166 Ne24a4a56e391478ab335612c671f721d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Spine
168 rdf:type schema:DefinedTerm
169 Ne4a74aa45bff42e7af0ea876912042fb rdf:first sg:person.01222601175.55
170 rdf:rest Nda05b7f9bd334cd2975834be9ca93288
171 Ne92270a6a76e4983bfa6b4dd9076b79c schema:name pubmed_id
172 schema:value 24196870
173 rdf:type schema:PropertyValue
174 Nea4f7bb19dd24d74990777d31d5d19ec schema:name Institute for Treatment and Rehabilitation “Niska Banja”, Nis, Serbia
175 rdf:type schema:Organization
176 Neddae1d69f014f919d0a38dd631a7ac9 schema:affiliation N0d28759047de4af98a20daf874810299
177 schema:familyName CulaficVojinovic
178 schema:givenName Violeta
179 rdf:type schema:Person
180 Nfdc533e0d0ef40f3979fae032a203d60 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
181 schema:name Multivariate Analysis
182 rdf:type schema:DefinedTerm
183 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
184 schema:name Medical and Health Sciences
185 rdf:type schema:DefinedTerm
186 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
187 schema:name Clinical Sciences
188 rdf:type schema:DefinedTerm
189 sg:journal.1312216 schema:issn 0914-8779
190 1435-5604
191 schema:name Journal of Bone and Mineral Metabolism
192 rdf:type schema:Periodical
193 sg:person.01061641462.43 schema:affiliation https://www.grid.ac/institutes/grid.8194.4
194 schema:familyName Poiana
195 schema:givenName Catalina
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01061641462.43
197 rdf:type schema:Person
198 sg:person.01106336063.60 schema:affiliation https://www.grid.ac/institutes/grid.410563.5
199 schema:familyName Petranova
200 schema:givenName Tzvetanka
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106336063.60
202 rdf:type schema:Person
203 sg:person.01144543125.50 schema:affiliation https://www.grid.ac/institutes/grid.8515.9
204 schema:familyName Hans
205 schema:givenName Didier
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01144543125.50
207 rdf:type schema:Person
208 sg:person.01166456174.94 schema:affiliation N9c77313b65da4002a86c2ecd94d8c94f
209 schema:familyName Vasic
210 schema:givenName Jelena
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01166456174.94
212 rdf:type schema:Person
213 sg:person.012065244037.40 schema:affiliation https://www.grid.ac/institutes/grid.419973.1
214 schema:familyName Povoroznyuk
215 schema:givenName Vladyslav
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012065244037.40
217 rdf:type schema:Person
218 sg:person.01222601175.55 schema:affiliation https://www.grid.ac/institutes/grid.8194.4
219 schema:familyName Barbu
220 schema:givenName Carmen Gabriela
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222601175.55
222 rdf:type schema:Person
223 sg:person.012231563115.71 schema:affiliation https://www.grid.ac/institutes/grid.419973.1
224 schema:familyName Dzerovych
225 schema:givenName Nataliia
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012231563115.71
227 rdf:type schema:Person
228 sg:person.0612751202.48 schema:affiliation Nea4f7bb19dd24d74990777d31d5d19ec
229 schema:familyName Dimic
230 schema:givenName Aleksandar
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0612751202.48
232 rdf:type schema:Person
233 sg:person.0616335654.92 schema:affiliation https://www.grid.ac/institutes/grid.410563.5
234 schema:familyName Rashkov
235 schema:givenName Rasho
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0616335654.92
237 rdf:type schema:Person
238 sg:person.0625413674.15 schema:affiliation N5751c80d1f584d7d8f42c44fa5106047
239 schema:familyName Karadzic
240 schema:givenName Mirjana
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625413674.15
242 rdf:type schema:Person
243 sg:person.0673527074.07 schema:affiliation N08e474e902ab470890f1ac70b2749bdd
244 schema:familyName Gojkovic
245 schema:givenName Filip
246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673527074.07
247 rdf:type schema:Person
248 sg:person.0712753573.30 schema:affiliation https://www.grid.ac/institutes/grid.414477.5
249 schema:familyName Winzenrieth
250 schema:givenName Renaud
251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0712753573.30
252 rdf:type schema:Person
253 sg:person.0741642274.15 schema:affiliation N90e20b9eed24413388547c18f026514e
254 schema:familyName Elez
255 schema:givenName Jelena
256 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741642274.15
257 rdf:type schema:Person
258 sg:pub.10.1007/s00198-009-1062-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033192394
259 https://doi.org/10.1007/s00198-009-1062-3
260 rdf:type schema:CreativeWork
261 sg:pub.10.1007/s00198-012-2008-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049829868
262 https://doi.org/10.1007/s00198-012-2008-8
263 rdf:type schema:CreativeWork
264 sg:pub.10.1007/s00198-012-2188-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049147904
265 https://doi.org/10.1007/s00198-012-2188-2
266 rdf:type schema:CreativeWork
267 sg:pub.10.1007/s00198-013-2316-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006849290
268 https://doi.org/10.1007/s00198-013-2316-7
269 rdf:type schema:CreativeWork
270 sg:pub.10.1007/s00198-015-3078-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037778668
271 https://doi.org/10.1007/s00198-015-3078-1
272 rdf:type schema:CreativeWork
273 sg:pub.10.1007/s00223-009-9322-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1022165572
274 https://doi.org/10.1007/s00223-009-9322-y
275 rdf:type schema:CreativeWork
276 https://app.dimensions.ai/details/publication/pub.1078492370 schema:CreativeWork
277 https://app.dimensions.ai/details/publication/pub.1082575724 schema:CreativeWork
278 https://doi.org/10.1002/1097-0142(1950)3:1<32::aid-cncr2820030106>3.0.co;2-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024768178
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1002/jbmr.1648 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033341246
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1002/jbmr.499 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030492867
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1002/sim.2929 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044960408
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1016/0021-9290(88)90008-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011397653
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1016/j.berh.2009.09.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048032412
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1016/j.bone.2005.11.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025281992
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1016/j.bone.2012.11.041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003743624
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1016/j.jocd.2011.05.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041135489
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1016/j.jocd.2012.01.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007409975
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1016/j.jocd.2012.05.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003129571
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1016/j.jocd.2012.08.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047306045
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1016/j.jocd.2013.05.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005011764
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1016/s8756-3282(00)00329-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1015677715
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1056/nejmra053077 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000793776
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1359/jbmr.050304 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042450609
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1359/jbmr.050610 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035905222
311 rdf:type schema:CreativeWork
312 https://www.grid.ac/institutes/grid.410563.5 schema:alternateName Medical University of Sofia
313 schema:name Clinic of Rheumatology, Medical University, Sofia, Bulgaria
314 rdf:type schema:Organization
315 https://www.grid.ac/institutes/grid.414477.5 schema:alternateName Hôpital Xavier Arnozan
316 schema:name R&D Department, Med-Imaps, PTIB, Hopital Xavier Arnozan, Avenue du Haut-Lévêque, 33600, Pessac, France
317 rdf:type schema:Organization
318 https://www.grid.ac/institutes/grid.419973.1 schema:alternateName National Academy of Medical Sciences of Ukraine
319 schema:name Department of Clinical Physiology and Pathology of Locomotor Apparatus, D.F. Chebotarev Institute of Gerontology NAMS Ukraine and Ukrainian Scientific-Medical Center for the Problems of Osteoporosis, Kiev, Ukraine
320 rdf:type schema:Organization
321 https://www.grid.ac/institutes/grid.8194.4 schema:alternateName Carol Davila University of Medicine and Pharmacy
322 schema:name Department of Endocrinology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
323 rdf:type schema:Organization
324 https://www.grid.ac/institutes/grid.8515.9 schema:alternateName University Hospital of Lausanne
325 schema:name Bone Diseases Center, DAL, Lausanne University Hospital, Lausanne, Switzerland
326 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...