Ontology type: schema:ScholarlyArticle
2015-08-09
AUTHORSYehui Duan, Fengna Li, Yinghui Li, Yulong Tang, Xiangfeng Kong, Zemeng Feng, Tracy G. Anthony, Malcolm Watford, Yongqing Hou, Guoyao Wu, Yulong Yin
ABSTRACTLeucine (Leu) is a nutritionally essential branched-chain amino acid (BCAA) in animal nutrition. It is usually one of the most abundant amino acids in high-quality protein foods. Leu increases protein synthesis through activation of the mammalian target of rapamycin (mTOR) signaling pathway in skeletal muscle, adipose tissue and placental cells. Leu promotes energy metabolism (glucose uptake, mitochondrial biogenesis, and fatty acid oxidation) to provide energy for protein synthesis, while inhibiting protein degradation. Approximately 80 % of Leu is normally used for protein synthesis, while the remainder is converted to α-ketoisocaproate (α-KIC) and β-hydroxy-β-methylbutyrate (HMB) in skeletal muscle. Therefore, it has been hypothesized that some of the functions of Leu are modulated by its metabolites. Both α-KIC and HMB have recently received considerable attention as nutritional supplements used to increase protein synthesis, inhibit protein degradation, and regulate energy homeostasis in a variety of in vitro and in vivo models. Leu and its metabolites hold great promise to enhance the growth and health of animals (including humans, birds and fish). More... »
PAGES41-51
http://scigraph.springernature.com/pub.10.1007/s00726-015-2067-1
DOIhttp://dx.doi.org/10.1007/s00726-015-2067-1
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/26255285
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"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s00726-015-2067-1"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"26255285"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s00726-015-2067-1",
"https://app.dimensions.ai/details/publication/pub.1041340932"
],
"sdDataset": "articles",
"sdDatePublished": "2022-08-04T17:03",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_656.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1007/s00726-015-2067-1"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00726-015-2067-1'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00726-015-2067-1'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00726-015-2067-1'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00726-015-2067-1'
This table displays all metadata directly associated to this object as RDF triples.
359 TRIPLES
21 PREDICATES
116 URIs
77 LITERALS
14 BLANK NODES