Differences in amino acids composition and coupling patterns between mesophilic and thermophilic proteins View Full Text


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Article Info

DATE

2008-01

AUTHORS

X.-X. Zhou, Y.-B. Wang, Y.-J. Pan, W.-F. Li

ABSTRACT

Thermophilic proteins show substantially higher intrinsic thermal stability than their mesophilic counterparts. Amino acid composition is believed to alter the intrinsic stability of proteins. Several investigations and mutagenesis experiment have been carried out to understand the amino acid composition for the thermostability of proteins. This review presents some generalized features of amino acid composition found in thermophilic proteins, including an increase in residue hydrophobicity, a decrease in uncharged polar residues, an increase in charged residues, an increase in aromatic residues, certain amino acid coupling patterns and amino acid preferences for thermophilic proteins. The differences of amino acids composition between thermophilic and mesophilic proteins are related to some properties of amino acids. These features provide guidelines for engineering mesophilic protein to thermophilic protein. More... »

PAGES

25-33

References to SciGraph publications

  • 2007-05. Molecular basis for thermal properties of Streptomyces thermovulgaris fumarase C hinge at hydrophilic amino acids R163, E170 and S347 in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
  • 2007-09. Applications and current challenges of proteomic approaches, focusing on two-dimensional electrophoresis in AMINO ACIDS
  • 2005-02. Biochemical properties of new synthetic carnosine analogues containing the residue of 2,3-diaminopropionic acid: the effect of N-acetylation in AMINO ACIDS
  • 2007-11. The digital language of amino acids in AMINO ACIDS
  • 2006-12. Analysis of Nanoarchaeum equitans genome and proteome composition: indications for hyperthermophilic and parasitic adaptation in BMC GENOMICS
  • 2005-10. Some like it hot: the structure and function of small heat-shock proteins in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2008-06. Novel chloroenyne-modified amino acid derivatives in AMINO ACIDS
  • 2006-06. Activity-based proteomics: enzymatic activity profiling in complex proteomes in AMINO ACIDS
  • 2007-05. Protein tyrosine nitration in hydrophilic and hydrophobic environments in AMINO ACIDS
  • 2001-08. How do thermophilic proteins deal with heat? in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 2000-05. The stability of thermophilic proteins: a study based on comprehensive genome comparison in FUNCTIONAL & INTEGRATIVE GENOMICS
  • 2008-04. A DING phosphatase in Thermus thermophilus in AMINO ACIDS
  • 2008-01. Using pseudo amino acid composition to predict transmembrane regions in protein: cellular automata and Lempel-Ziv complexity in AMINO ACIDS
  • 2002-07. Preferred codons and amino acid couples in hyperthermophiles in GENOME BIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00726-007-0589-x

    DOI

    http://dx.doi.org/10.1007/s00726-007-0589-x

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1044246236

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/17710363


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