Matrix adhesive system containing plant extract View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-02-10

AUTHORS

Terézia Haršányová, Katarína Bauerová, Desana Matušová

ABSTRACT

This work refers formulation of transdermal drug delivery system containing extract from Rhodiola rosea. A polymer matrix controls the rate at which the drug contained in the patch reservoir can pass through the skin into bloodstream. Transdermal patches are useful in developing new applications for existing therapeutics and reducing first-pass effect. Qualitative properties, e.g., patch adhesion or dissolution of drug, are important by formulation of the system influencing the bioavailability. Based on tested parameters, the most promising formulations were matrix systems containing two different combinations: gelatine with chitosan or pectin with polyethylene oxide. These two selected matrix systems will be further evaluated to study the drug permeation.Graphical abstract More... »

PAGES

883-885

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00706-017-2139-x

DOI

http://dx.doi.org/10.1007/s00706-017-2139-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1100960519


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0303", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Macromolecular and Materials Chemistry", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Galenic Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic", 
          "id": "http://www.grid.ac/institutes/grid.7634.6", 
          "name": [
            "Department of Galenic Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Har\u0161\u00e1nyov\u00e1", 
        "givenName": "Ter\u00e9zia", 
        "id": "sg:person.013636265424.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013636265424.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, Slovak Republic", 
          "id": "http://www.grid.ac/institutes/grid.482596.4", 
          "name": [
            "Department of Galenic Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic", 
            "Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, Slovak Republic"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bauerov\u00e1", 
        "givenName": "Katar\u00edna", 
        "id": "sg:person.0710734666.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710734666.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Galenic Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic", 
          "id": "http://www.grid.ac/institutes/grid.7634.6", 
          "name": [
            "Department of Galenic Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matu\u0161ov\u00e1", 
        "givenName": "Desana", 
        "id": "sg:person.0616633765.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0616633765.20"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2018-02-10", 
    "datePublishedReg": "2018-02-10", 
    "description": "This work refers formulation of transdermal drug delivery system containing extract from Rhodiola rosea. A polymer matrix controls the rate at which the drug contained in the patch reservoir can pass through the skin into bloodstream. Transdermal patches are useful in developing new applications for existing therapeutics and reducing first-pass effect. Qualitative properties, e.g., patch adhesion or dissolution of drug, are important by formulation of the system influencing the bioavailability. Based on tested parameters, the most promising formulations were matrix systems containing two different combinations: gelatine with chitosan or pectin with polyethylene oxide. These two selected matrix systems will be further evaluated to study the drug permeation.Graphical abstract", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00706-017-2139-x", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.5521889", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1345587", 
        "issn": [
          "0343-7329", 
          "0026-9247"
        ], 
        "name": "Monatshefte f\u00fcr Chemie - Chemical Monthly", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "149"
      }
    ], 
    "keywords": [
      "dissolution of drug", 
      "drug delivery systems", 
      "transdermal drug delivery system", 
      "polyethylene oxide", 
      "polymer matrix", 
      "drug permeation", 
      "matrix system", 
      "promising formulation", 
      "delivery system", 
      "plant extracts", 
      "new applications", 
      "chitosan", 
      "first-pass effect", 
      "dissolution", 
      "oxide", 
      "permeation", 
      "transdermal patch", 
      "bioavailability", 
      "properties", 
      "adhesive systems", 
      "formulation", 
      "pectin", 
      "patch adhesion", 
      "extracts", 
      "drugs", 
      "Rhodiola rosea", 
      "matrix", 
      "adhesion", 
      "applications", 
      "therapeutics", 
      "system", 
      "work", 
      "parameters", 
      "different combinations", 
      "effect", 
      "combination", 
      "rate", 
      "reservoir", 
      "bloodstream", 
      "rosea", 
      "qualitative properties", 
      "skin", 
      "patches", 
      "patch reservoir", 
      "Graphical abstract Matrix adhesive system", 
      "abstract Matrix adhesive system", 
      "Matrix adhesive system"
    ], 
    "name": "Matrix adhesive system containing plant extract", 
    "pagination": "883-885", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1100960519"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00706-017-2139-x"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00706-017-2139-x", 
      "https://app.dimensions.ai/details/publication/pub.1100960519"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-12-01T19:40", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_760.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00706-017-2139-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00706-017-2139-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00706-017-2139-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00706-017-2139-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00706-017-2139-x'


 

This table displays all metadata directly associated to this object as RDF triples.

125 TRIPLES      21 PREDICATES      72 URIs      64 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00706-017-2139-x schema:about anzsrc-for:03
2 anzsrc-for:0303
3 schema:author N519f56eb16594f5d83f9d2e55c8a6232
4 schema:datePublished 2018-02-10
5 schema:datePublishedReg 2018-02-10
6 schema:description This work refers formulation of transdermal drug delivery system containing extract from Rhodiola rosea. A polymer matrix controls the rate at which the drug contained in the patch reservoir can pass through the skin into bloodstream. Transdermal patches are useful in developing new applications for existing therapeutics and reducing first-pass effect. Qualitative properties, e.g., patch adhesion or dissolution of drug, are important by formulation of the system influencing the bioavailability. Based on tested parameters, the most promising formulations were matrix systems containing two different combinations: gelatine with chitosan or pectin with polyethylene oxide. These two selected matrix systems will be further evaluated to study the drug permeation.Graphical abstract
7 schema:genre article
8 schema:inLanguage en
9 schema:isAccessibleForFree false
10 schema:isPartOf N69212fe971a74f3f9ddf3f0ba1bfda5b
11 Ne6bdbd577107441f987e355425dbd683
12 sg:journal.1345587
13 schema:keywords Graphical abstract Matrix adhesive system
14 Matrix adhesive system
15 Rhodiola rosea
16 abstract Matrix adhesive system
17 adhesion
18 adhesive systems
19 applications
20 bioavailability
21 bloodstream
22 chitosan
23 combination
24 delivery system
25 different combinations
26 dissolution
27 dissolution of drug
28 drug delivery systems
29 drug permeation
30 drugs
31 effect
32 extracts
33 first-pass effect
34 formulation
35 matrix
36 matrix system
37 new applications
38 oxide
39 parameters
40 patch adhesion
41 patch reservoir
42 patches
43 pectin
44 permeation
45 plant extracts
46 polyethylene oxide
47 polymer matrix
48 promising formulation
49 properties
50 qualitative properties
51 rate
52 reservoir
53 rosea
54 skin
55 system
56 therapeutics
57 transdermal drug delivery system
58 transdermal patch
59 work
60 schema:name Matrix adhesive system containing plant extract
61 schema:pagination 883-885
62 schema:productId N25e66676938146dc9a9d0d0657afe9e6
63 N508f39f150494aea8c0e422415be8f88
64 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100960519
65 https://doi.org/10.1007/s00706-017-2139-x
66 schema:sdDatePublished 2021-12-01T19:40
67 schema:sdLicense https://scigraph.springernature.com/explorer/license/
68 schema:sdPublisher N2a65c83424514e9abc22d44bc5825c97
69 schema:url https://doi.org/10.1007/s00706-017-2139-x
70 sgo:license sg:explorer/license/
71 sgo:sdDataset articles
72 rdf:type schema:ScholarlyArticle
73 N25e66676938146dc9a9d0d0657afe9e6 schema:name doi
74 schema:value 10.1007/s00706-017-2139-x
75 rdf:type schema:PropertyValue
76 N2a65c83424514e9abc22d44bc5825c97 schema:name Springer Nature - SN SciGraph project
77 rdf:type schema:Organization
78 N30ad759a87574f90ab0fb9cb55036bb1 rdf:first sg:person.0616633765.20
79 rdf:rest rdf:nil
80 N508f39f150494aea8c0e422415be8f88 schema:name dimensions_id
81 schema:value pub.1100960519
82 rdf:type schema:PropertyValue
83 N519f56eb16594f5d83f9d2e55c8a6232 rdf:first sg:person.013636265424.74
84 rdf:rest Ne23b8dc2959d42e3a7a3663bbc0aeec1
85 N69212fe971a74f3f9ddf3f0ba1bfda5b schema:issueNumber 5
86 rdf:type schema:PublicationIssue
87 Ne23b8dc2959d42e3a7a3663bbc0aeec1 rdf:first sg:person.0710734666.94
88 rdf:rest N30ad759a87574f90ab0fb9cb55036bb1
89 Ne6bdbd577107441f987e355425dbd683 schema:volumeNumber 149
90 rdf:type schema:PublicationVolume
91 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
92 schema:name Chemical Sciences
93 rdf:type schema:DefinedTerm
94 anzsrc-for:0303 schema:inDefinedTermSet anzsrc-for:
95 schema:name Macromolecular and Materials Chemistry
96 rdf:type schema:DefinedTerm
97 sg:grant.5521889 http://pending.schema.org/fundedItem sg:pub.10.1007/s00706-017-2139-x
98 rdf:type schema:MonetaryGrant
99 sg:journal.1345587 schema:issn 0026-9247
100 0343-7329
101 schema:name Monatshefte für Chemie - Chemical Monthly
102 schema:publisher Springer Nature
103 rdf:type schema:Periodical
104 sg:person.013636265424.74 schema:affiliation grid-institutes:grid.7634.6
105 schema:familyName Haršányová
106 schema:givenName Terézia
107 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013636265424.74
108 rdf:type schema:Person
109 sg:person.0616633765.20 schema:affiliation grid-institutes:grid.7634.6
110 schema:familyName Matušová
111 schema:givenName Desana
112 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0616633765.20
113 rdf:type schema:Person
114 sg:person.0710734666.94 schema:affiliation grid-institutes:grid.482596.4
115 schema:familyName Bauerová
116 schema:givenName Katarína
117 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710734666.94
118 rdf:type schema:Person
119 grid-institutes:grid.482596.4 schema:alternateName Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, Slovak Republic
120 schema:name Department of Galenic Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic
121 Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, Slovak Republic
122 rdf:type schema:Organization
123 grid-institutes:grid.7634.6 schema:alternateName Department of Galenic Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic
124 schema:name Department of Galenic Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic
125 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...