Design, synthesis, and evaluation of novel hydrazide hydrochlorides of 6-aminopyrazolo[1,5-a]pyrimidine-3-carboxamides as potent Aurora kinase inhibitors View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-10

AUTHORS

A. K. Ajeesh Kumar, Yadav D. Bodke, Ganesh Sambasivam, Peter Serjious Lakra

ABSTRACT

The Aurora kinases play a key role in mitosis and are overexpressed in multiple human tumor types; there has been considerable interest in developing Aurora kinase inhibitors as antitumor agents, particularly Aurora A and Aurora B kinases. A series of novel hydrazide hydrochlorides of pyrazolo[1,5-a]pyrimidine carboxamides were designed and synthesized and their inhibitory activities against Aurora kinases were evaluated. Some of the tested compounds exhibited low micromolar to nanomolar activity with respect to the inhibition of Aurora A kinase. The most potent compound in this series was found to be a potent inhibitor of Aurora A in an HTRF enzymatic assay with an IC50 as low as 23 nM. A structure–activity relationship study indicated that halogen substitution in the benzene ring of amide plays an important role in kinase inhibitory potency. More... »

PAGES

1767-1780

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00706-017-1943-7

DOI

http://dx.doi.org/10.1007/s00706-017-1943-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1090312596


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1115", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Pharmacology and Pharmaceutical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Anthem Biosciences (India)", 
          "id": "https://www.grid.ac/institutes/grid.464725.6", 
          "name": [
            "Anthem Biosciences Pvt. Ltd., # 49, Bommasandra Industrial Area, Bommasandra, 560 099, Bangalore, Karnataka, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kumar", 
        "givenName": "A. K. Ajeesh", 
        "id": "sg:person.010112312033.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010112312033.92"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kuvempu University", 
          "id": "https://www.grid.ac/institutes/grid.440695.a", 
          "name": [
            "Department of PG Studies and Research in Industrial Chemistry, School of Chemical Sciences, Kuvempu University, Shankaraghatta, 577 451, Shimoga, Karnataka, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bodke", 
        "givenName": "Yadav D.", 
        "id": "sg:person.0736461640.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736461640.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Anthem Biosciences (India)", 
          "id": "https://www.grid.ac/institutes/grid.464725.6", 
          "name": [
            "Anthem Biosciences Pvt. Ltd., # 49, Bommasandra Industrial Area, Bommasandra, 560 099, Bangalore, Karnataka, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sambasivam", 
        "givenName": "Ganesh", 
        "id": "sg:person.015765142153.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015765142153.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Anthem Biosciences (India)", 
          "id": "https://www.grid.ac/institutes/grid.464725.6", 
          "name": [
            "Anthem Biosciences Pvt. Ltd., # 49, Bommasandra Industrial Area, Bommasandra, 560 099, Bangalore, Karnataka, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lakra", 
        "givenName": "Peter Serjious", 
        "id": "sg:person.015737721215.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015737721215.39"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1158/1535-7163.mct-09-0609", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003148796"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1535-7163.mct-07-0444", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007236387"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1023789416385", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012375753", 
          "https://doi.org/10.1023/a:1023789416385"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm1003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014550555", 
          "https://doi.org/10.1038/nm1003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm1003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014550555", 
          "https://doi.org/10.1038/nm1003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.seminoncol.2015.09.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016210180"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00706-016-1723-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016579517", 
          "https://doi.org/10.1007/s00706-016-1723-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1541-7786.mcr-06-0208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024275803"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-06-1405", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029425463"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc1526", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034468320", 
          "https://doi.org/10.1038/nrc1526"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc1526", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034468320", 
          "https://doi.org/10.1038/nrc1526"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fonc.2015.00278", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035106163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm1245", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049953107", 
          "https://doi.org/10.1038/nrm1245"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm1245", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049953107", 
          "https://doi.org/10.1038/nrm1245"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/cb100053q", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055225818"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja903049z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055861309"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja903049z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055861309"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm061335f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055950895"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm061335f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055950895"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm8012129", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055956042"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm8012129", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055956042"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ol016333y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056241820"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ol016333y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056241820"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ol0166808", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056242004"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ol0166808", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056242004"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075125162", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-10", 
    "datePublishedReg": "2017-10-01", 
    "description": "The Aurora kinases play a key role in mitosis and are overexpressed in multiple human tumor types; there has been considerable interest in developing Aurora kinase inhibitors as antitumor agents, particularly Aurora A and Aurora B kinases. A series of novel hydrazide hydrochlorides of pyrazolo[1,5-a]pyrimidine carboxamides were designed and synthesized and their inhibitory activities against Aurora kinases were evaluated. Some of the tested compounds exhibited low micromolar to nanomolar activity with respect to the inhibition of Aurora A kinase. The most potent compound in this series was found to be a potent inhibitor of Aurora A in an HTRF enzymatic assay with an IC50 as low as 23 nM. A structure\u2013activity relationship study indicated that halogen substitution in the benzene ring of amide plays an important role in kinase inhibitory potency. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00706-017-1943-7", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1345587", 
        "issn": [
          "0343-7329", 
          "0026-9247"
        ], 
        "name": "Monatshefte f\u00fcr Chemie - Chemical Monthly", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "10", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "148"
      }
    ], 
    "name": "Design, synthesis, and evaluation of novel hydrazide hydrochlorides of 6-aminopyrazolo[1,5-a]pyrimidine-3-carboxamides as potent Aurora kinase inhibitors", 
    "pagination": "1767-1780", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "4725578f3de32033c2dd02b05655955031ae169f686399deddf97043091c2ba4"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00706-017-1943-7"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1090312596"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00706-017-1943-7", 
      "https://app.dimensions.ai/details/publication/pub.1090312596"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:21", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000362_0000000362/records_87078_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs00706-017-1943-7"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00706-017-1943-7'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00706-017-1943-7'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00706-017-1943-7'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00706-017-1943-7'


 

This table displays all metadata directly associated to this object as RDF triples.

143 TRIPLES      21 PREDICATES      45 URIs      19 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00706-017-1943-7 schema:about anzsrc-for:11
2 anzsrc-for:1115
3 schema:author Nd83e2dd40d6640c3a8cb65a8e9b2b921
4 schema:citation sg:pub.10.1007/s00706-016-1723-9
5 sg:pub.10.1023/a:1023789416385
6 sg:pub.10.1038/nm1003
7 sg:pub.10.1038/nrc1526
8 sg:pub.10.1038/nrm1245
9 https://app.dimensions.ai/details/publication/pub.1075125162
10 https://doi.org/10.1021/cb100053q
11 https://doi.org/10.1021/ja903049z
12 https://doi.org/10.1021/jm061335f
13 https://doi.org/10.1021/jm8012129
14 https://doi.org/10.1021/ol016333y
15 https://doi.org/10.1021/ol0166808
16 https://doi.org/10.1053/j.seminoncol.2015.09.022
17 https://doi.org/10.1158/1078-0432.ccr-06-1405
18 https://doi.org/10.1158/1535-7163.mct-07-0444
19 https://doi.org/10.1158/1535-7163.mct-09-0609
20 https://doi.org/10.1158/1541-7786.mcr-06-0208
21 https://doi.org/10.3389/fonc.2015.00278
22 schema:datePublished 2017-10
23 schema:datePublishedReg 2017-10-01
24 schema:description The Aurora kinases play a key role in mitosis and are overexpressed in multiple human tumor types; there has been considerable interest in developing Aurora kinase inhibitors as antitumor agents, particularly Aurora A and Aurora B kinases. A series of novel hydrazide hydrochlorides of pyrazolo[1,5-a]pyrimidine carboxamides were designed and synthesized and their inhibitory activities against Aurora kinases were evaluated. Some of the tested compounds exhibited low micromolar to nanomolar activity with respect to the inhibition of Aurora A kinase. The most potent compound in this series was found to be a potent inhibitor of Aurora A in an HTRF enzymatic assay with an IC50 as low as 23 nM. A structure–activity relationship study indicated that halogen substitution in the benzene ring of amide plays an important role in kinase inhibitory potency.
25 schema:genre research_article
26 schema:inLanguage en
27 schema:isAccessibleForFree false
28 schema:isPartOf N37d1d11ae3d14cd5aba4bb5eedf14330
29 N49566b60cd66449e90de3a0d1a7347f0
30 sg:journal.1345587
31 schema:name Design, synthesis, and evaluation of novel hydrazide hydrochlorides of 6-aminopyrazolo[1,5-a]pyrimidine-3-carboxamides as potent Aurora kinase inhibitors
32 schema:pagination 1767-1780
33 schema:productId N6ec5ec9faa8b43be8f088e3c75dd9a05
34 N951c024cce644f3898e15260ce671127
35 Nf33d63034a3e4e30b1be1099daed9292
36 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090312596
37 https://doi.org/10.1007/s00706-017-1943-7
38 schema:sdDatePublished 2019-04-11T12:21
39 schema:sdLicense https://scigraph.springernature.com/explorer/license/
40 schema:sdPublisher N2e32cb4dfad9444ebe38ac12a5ab6aff
41 schema:url https://link.springer.com/10.1007%2Fs00706-017-1943-7
42 sgo:license sg:explorer/license/
43 sgo:sdDataset articles
44 rdf:type schema:ScholarlyArticle
45 N2e32cb4dfad9444ebe38ac12a5ab6aff schema:name Springer Nature - SN SciGraph project
46 rdf:type schema:Organization
47 N37d1d11ae3d14cd5aba4bb5eedf14330 schema:volumeNumber 148
48 rdf:type schema:PublicationVolume
49 N49566b60cd66449e90de3a0d1a7347f0 schema:issueNumber 10
50 rdf:type schema:PublicationIssue
51 N6ec5ec9faa8b43be8f088e3c75dd9a05 schema:name readcube_id
52 schema:value 4725578f3de32033c2dd02b05655955031ae169f686399deddf97043091c2ba4
53 rdf:type schema:PropertyValue
54 N8844e6d5e81e4488a2169e8ca3844ec0 rdf:first sg:person.015765142153.50
55 rdf:rest Nfff33d29e53d4467a066a33bcafa4caa
56 N951c024cce644f3898e15260ce671127 schema:name doi
57 schema:value 10.1007/s00706-017-1943-7
58 rdf:type schema:PropertyValue
59 Nd83e2dd40d6640c3a8cb65a8e9b2b921 rdf:first sg:person.010112312033.92
60 rdf:rest Nff80c06546114fff8b52fae809b18f69
61 Nf33d63034a3e4e30b1be1099daed9292 schema:name dimensions_id
62 schema:value pub.1090312596
63 rdf:type schema:PropertyValue
64 Nff80c06546114fff8b52fae809b18f69 rdf:first sg:person.0736461640.68
65 rdf:rest N8844e6d5e81e4488a2169e8ca3844ec0
66 Nfff33d29e53d4467a066a33bcafa4caa rdf:first sg:person.015737721215.39
67 rdf:rest rdf:nil
68 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
69 schema:name Medical and Health Sciences
70 rdf:type schema:DefinedTerm
71 anzsrc-for:1115 schema:inDefinedTermSet anzsrc-for:
72 schema:name Pharmacology and Pharmaceutical Sciences
73 rdf:type schema:DefinedTerm
74 sg:journal.1345587 schema:issn 0026-9247
75 0343-7329
76 schema:name Monatshefte für Chemie - Chemical Monthly
77 rdf:type schema:Periodical
78 sg:person.010112312033.92 schema:affiliation https://www.grid.ac/institutes/grid.464725.6
79 schema:familyName Kumar
80 schema:givenName A. K. Ajeesh
81 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010112312033.92
82 rdf:type schema:Person
83 sg:person.015737721215.39 schema:affiliation https://www.grid.ac/institutes/grid.464725.6
84 schema:familyName Lakra
85 schema:givenName Peter Serjious
86 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015737721215.39
87 rdf:type schema:Person
88 sg:person.015765142153.50 schema:affiliation https://www.grid.ac/institutes/grid.464725.6
89 schema:familyName Sambasivam
90 schema:givenName Ganesh
91 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015765142153.50
92 rdf:type schema:Person
93 sg:person.0736461640.68 schema:affiliation https://www.grid.ac/institutes/grid.440695.a
94 schema:familyName Bodke
95 schema:givenName Yadav D.
96 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736461640.68
97 rdf:type schema:Person
98 sg:pub.10.1007/s00706-016-1723-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016579517
99 https://doi.org/10.1007/s00706-016-1723-9
100 rdf:type schema:CreativeWork
101 sg:pub.10.1023/a:1023789416385 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012375753
102 https://doi.org/10.1023/a:1023789416385
103 rdf:type schema:CreativeWork
104 sg:pub.10.1038/nm1003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014550555
105 https://doi.org/10.1038/nm1003
106 rdf:type schema:CreativeWork
107 sg:pub.10.1038/nrc1526 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034468320
108 https://doi.org/10.1038/nrc1526
109 rdf:type schema:CreativeWork
110 sg:pub.10.1038/nrm1245 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049953107
111 https://doi.org/10.1038/nrm1245
112 rdf:type schema:CreativeWork
113 https://app.dimensions.ai/details/publication/pub.1075125162 schema:CreativeWork
114 https://doi.org/10.1021/cb100053q schema:sameAs https://app.dimensions.ai/details/publication/pub.1055225818
115 rdf:type schema:CreativeWork
116 https://doi.org/10.1021/ja903049z schema:sameAs https://app.dimensions.ai/details/publication/pub.1055861309
117 rdf:type schema:CreativeWork
118 https://doi.org/10.1021/jm061335f schema:sameAs https://app.dimensions.ai/details/publication/pub.1055950895
119 rdf:type schema:CreativeWork
120 https://doi.org/10.1021/jm8012129 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055956042
121 rdf:type schema:CreativeWork
122 https://doi.org/10.1021/ol016333y schema:sameAs https://app.dimensions.ai/details/publication/pub.1056241820
123 rdf:type schema:CreativeWork
124 https://doi.org/10.1021/ol0166808 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056242004
125 rdf:type schema:CreativeWork
126 https://doi.org/10.1053/j.seminoncol.2015.09.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016210180
127 rdf:type schema:CreativeWork
128 https://doi.org/10.1158/1078-0432.ccr-06-1405 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029425463
129 rdf:type schema:CreativeWork
130 https://doi.org/10.1158/1535-7163.mct-07-0444 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007236387
131 rdf:type schema:CreativeWork
132 https://doi.org/10.1158/1535-7163.mct-09-0609 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003148796
133 rdf:type schema:CreativeWork
134 https://doi.org/10.1158/1541-7786.mcr-06-0208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024275803
135 rdf:type schema:CreativeWork
136 https://doi.org/10.3389/fonc.2015.00278 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035106163
137 rdf:type schema:CreativeWork
138 https://www.grid.ac/institutes/grid.440695.a schema:alternateName Kuvempu University
139 schema:name Department of PG Studies and Research in Industrial Chemistry, School of Chemical Sciences, Kuvempu University, Shankaraghatta, 577 451, Shimoga, Karnataka, India
140 rdf:type schema:Organization
141 https://www.grid.ac/institutes/grid.464725.6 schema:alternateName Anthem Biosciences (India)
142 schema:name Anthem Biosciences Pvt. Ltd., # 49, Bommasandra Industrial Area, Bommasandra, 560 099, Bangalore, Karnataka, India
143 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...