Experimental infection of colostrum deprived piglets with porcine circovirus 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) potentiates ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-12

AUTHORS

G. M. Allan, F. McNeilly, J. Ellis, S. Krakowka, B. Meehan, I. McNair, I. Walker, S. Kennedy

ABSTRACT

Experimental infection of colostrum-deprived (CD) pigs with a combined inoculum of porcine circovirus 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) potentiated the replication and distribution of PCV2 virus, when compared with pigs inoculated with PCV2 alone. The replication and distribution of PRRSV in dually infected pigs was not enhanced, when compared to pigs inoculated with PRRSV alone. The mechanisms involved in the potentiation of PCV2 replication in PCV2/PRRSV and PCV2/porcine parvovirus (PPV) dually infected pigs may relate to the fact that monocyte/macrophage cell types are common targets of these 3 viruses. More... »

PAGES

2421-2429

Journal

TITLE

Archives of Virology

ISSUE

11

VOLUME

145

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s007050070031

    DOI

    http://dx.doi.org/10.1007/s007050070031

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1008978018

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/11205128


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