Evaluation of the replication and pathogenicity of a variant avian paramyxovirus serotype 6 in mice View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-10

AUTHORS

Vuong Nghia Bui, Dai Quang Trinh, Lary N. B. Abao, Yuki Ozeki, Jonathan Runstadler, Kikuyasu Nakamura, Haruko Ogawa, Kunitoshi Imai

ABSTRACT

Avian paramyxoviruses (APMVs) have been evaluated for their potential use as vaccine vectors, sparking research efforts leading to a better understanding of APMVs' replication and pathogenicity. However, within APMV serotypes, significant genetic diversity exists, and the infectivity of variant strains in mammals has not been studied. We utilized a mouse model to evaluate the pathogenicity of a variant strain of APMV-6 (APMV-6/red-necked stint/Japan/8KS0813/2008) in comparison with the prototype APMV-6 strain (APMV-6/duck/Hong Kong/18/199/1977). Although the two viruses differ substantially, both genetically and antigenically, we found that the variant and prototype strains could similarly replicate in respiratory tissues of infected mice and induce respiratory disease, sometimes resulting in death of the mice. Both viruses induced a humoral immune response that could be clearly detected by ELISA but which was poorly recognized by the hemagglutination inhibition test. More... »

PAGES

3035-3043

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00705-017-3459-1

DOI

http://dx.doi.org/10.1007/s00705-017-3459-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1090364169

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28685285


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Avulavirus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Variation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred BALB C", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Serogroup", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Virus Replication", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "National Institute of Veterinary Research", 
          "id": "https://www.grid.ac/institutes/grid.419675.8", 
          "name": [
            "Diagnostic Center for Animal Health and Food Safety, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, 080-8555, Obihiro, Hokkaido, Japan", 
            "National Institute of Veterinary Research, 86 Truong Chinh, Dong Da, Hanoi, Vietnam"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bui", 
        "givenName": "Vuong Nghia", 
        "id": "sg:person.01110615363.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110615363.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institute of Veterinary Research", 
          "id": "https://www.grid.ac/institutes/grid.419675.8", 
          "name": [
            "Diagnostic Center for Animal Health and Food Safety, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, 080-8555, Obihiro, Hokkaido, Japan", 
            "National Institute of Veterinary Research, 86 Truong Chinh, Dong Da, Hanoi, Vietnam"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Trinh", 
        "givenName": "Dai Quang", 
        "id": "sg:person.01032425414.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01032425414.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Obihiro University of Agriculture and Veterinary Medicine", 
          "id": "https://www.grid.ac/institutes/grid.412310.5", 
          "name": [
            "Diagnostic Center for Animal Health and Food Safety, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, 080-8555, Obihiro, Hokkaido, Japan", 
            "Department of Agriculture-Agribusiness and Marketing Assistance Service, 1101, Quezon City, Philippines"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abao", 
        "givenName": "Lary N. B.", 
        "id": "sg:person.0757445370.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757445370.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Obihiro University of Agriculture and Veterinary Medicine", 
          "id": "https://www.grid.ac/institutes/grid.412310.5", 
          "name": [
            "Diagnostic Center for Animal Health and Food Safety, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, 080-8555, Obihiro, Hokkaido, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ozeki", 
        "givenName": "Yuki", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Massachusetts Institute of Technology", 
          "id": "https://www.grid.ac/institutes/grid.116068.8", 
          "name": [
            "Massachusetts Institute of Technology, 02139, Cambridge, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Runstadler", 
        "givenName": "Jonathan", 
        "id": "sg:person.0605647442.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605647442.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institute of Animal Health", 
          "id": "https://www.grid.ac/institutes/grid.416882.1", 
          "name": [
            "National Institute of Animal Health, 305-0856, Tsukuba, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakamura", 
        "givenName": "Kikuyasu", 
        "id": "sg:person.01137107407.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01137107407.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Obihiro University of Agriculture and Veterinary Medicine", 
          "id": "https://www.grid.ac/institutes/grid.412310.5", 
          "name": [
            "Diagnostic Center for Animal Health and Food Safety, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, 080-8555, Obihiro, Hokkaido, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ogawa", 
        "givenName": "Haruko", 
        "id": "sg:person.0671511241.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671511241.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Obihiro University of Agriculture and Veterinary Medicine", 
          "id": "https://www.grid.ac/institutes/grid.412310.5", 
          "name": [
            "Diagnostic Center for Animal Health and Food Safety, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, 080-8555, Obihiro, Hokkaido, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Imai", 
        "givenName": "Kunitoshi", 
        "id": "sg:person.0623376041.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623376041.99"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.virusres.2010.06.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003949964"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7589/0090-3558-27.1.123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004410135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/viro.1993.1325", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004593326"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7589/0090-3558-31.1.66", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010781070"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00705-016-2880-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011099812", 
          "https://doi.org/10.1007/s00705-016-2880-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11262-010-0479-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012527952", 
          "https://doi.org/10.1007/s11262-010-0479-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11262-010-0479-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012527952", 
          "https://doi.org/10.1007/s11262-010-0479-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-59745-561-9_30", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013027638", 
          "https://doi.org/10.1007/978-1-59745-561-9_30"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.00822-10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024393192"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/03079450802216645", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025008879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01310856", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025328943", 
          "https://doi.org/10.1007/bf01310856"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01310856", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025328943", 
          "https://doi.org/10.1007/bf01310856"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1292/jvms.14-0529", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025908110"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0016776", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027224793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.virol.2011.11.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029474993"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.00946-12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030850666"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.meegid.2012.07.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036409460"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00705-014-2162-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037307032", 
          "https://doi.org/10.1007/s00705-014-2162-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1297-9716-42-38", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039147381", 
          "https://doi.org/10.1186/1297-9716-42-38"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00705-013-1735-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040534165", 
          "https://doi.org/10.1007/s00705-013-1735-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0075456", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041997531"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.micinf.2011.01.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043031753"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2012/708216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043700037"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.01406-07", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045491259"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.virusres.2016.11.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049194627"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.virusres.2009.12.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052839398"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.virusres.2010.02.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053680330"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/0022-1317-49-2-255", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060353619"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/0022-1317-67-3-427", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060355996"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/vr.115.25-26.653", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062827435"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/vr.115.25-26.653", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062827435"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.20506/rst.19.2.1231", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068791751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.20506/rst.19.2.1231", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068791751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2105/ajph.42.6.672", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068858310"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076885396", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077598305", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-10", 
    "datePublishedReg": "2017-10-01", 
    "description": "Avian paramyxoviruses (APMVs) have been evaluated for their potential use as vaccine vectors, sparking research efforts leading to a better understanding of APMVs' replication and pathogenicity. However, within APMV serotypes, significant genetic diversity exists, and the infectivity of variant strains in mammals has not been studied. We utilized a mouse model to evaluate the pathogenicity of a variant strain of APMV-6 (APMV-6/red-necked stint/Japan/8KS0813/2008) in comparison with the prototype APMV-6 strain (APMV-6/duck/Hong Kong/18/199/1977). Although the two viruses differ substantially, both genetically and antigenically, we found that the variant and prototype strains could similarly replicate in respiratory tissues of infected mice and induce respiratory disease, sometimes resulting in death of the mice. Both viruses induced a humoral immune response that could be clearly detected by ELISA but which was poorly recognized by the hemagglutination inhibition test.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00705-017-3459-1", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.5977328", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1083335", 
        "issn": [
          "0304-8608", 
          "1432-8798"
        ], 
        "name": "Archives of Virology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "10", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "162"
      }
    ], 
    "name": "Evaluation of the replication and pathogenicity of a variant avian paramyxovirus serotype 6 in mice", 
    "pagination": "3035-3043", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "1587774dbd5bfab4c409268a4792a5b220dca794f56dab0350d59f63d5b3075b"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28685285"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7506870"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00705-017-3459-1"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1090364169"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00705-017-3459-1", 
      "https://app.dimensions.ai/details/publication/pub.1090364169"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T09:59", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89814_00000003.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs00705-017-3459-1"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00705-017-3459-1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00705-017-3459-1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00705-017-3459-1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00705-017-3459-1'


 

This table displays all metadata directly associated to this object as RDF triples.

267 TRIPLES      21 PREDICATES      70 URIs      30 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00705-017-3459-1 schema:about N01d54f86769b4ccfa58cb5ca17fdffaa
2 N4a0d3204ce814390ac21a12621889b52
3 N55cacae7a11c4f828372da381b50f334
4 N5f686637ea3e4e1fb33214944fc229dd
5 N8c5bb60e08d2428aae9ce4e101d54dd0
6 Nbb4be555464645ca8aa2737b7764ddf5
7 Nc380bdc179b0423ba29c6aeb07106aaa
8 Nd271003cfc774c8b9d25a85c37617f48
9 Nf599a470f68f47a29d7c65357771be8a
10 anzsrc-for:11
11 anzsrc-for:1107
12 schema:author Nce66ca02689243e48c2dccc1774db9b0
13 schema:citation sg:pub.10.1007/978-1-59745-561-9_30
14 sg:pub.10.1007/bf01310856
15 sg:pub.10.1007/s00705-013-1735-2
16 sg:pub.10.1007/s00705-014-2162-8
17 sg:pub.10.1007/s00705-016-2880-1
18 sg:pub.10.1007/s11262-010-0479-2
19 sg:pub.10.1186/1297-9716-42-38
20 https://app.dimensions.ai/details/publication/pub.1076885396
21 https://app.dimensions.ai/details/publication/pub.1077598305
22 https://doi.org/10.1006/viro.1993.1325
23 https://doi.org/10.1016/j.meegid.2012.07.012
24 https://doi.org/10.1016/j.micinf.2011.01.014
25 https://doi.org/10.1016/j.virol.2011.11.019
26 https://doi.org/10.1016/j.virusres.2009.12.015
27 https://doi.org/10.1016/j.virusres.2010.02.015
28 https://doi.org/10.1016/j.virusres.2010.06.009
29 https://doi.org/10.1016/j.virusres.2016.11.018
30 https://doi.org/10.1080/03079450802216645
31 https://doi.org/10.1099/0022-1317-49-2-255
32 https://doi.org/10.1099/0022-1317-67-3-427
33 https://doi.org/10.1128/jvi.00822-10
34 https://doi.org/10.1128/jvi.00946-12
35 https://doi.org/10.1128/jvi.01406-07
36 https://doi.org/10.1136/vr.115.25-26.653
37 https://doi.org/10.1155/2012/708216
38 https://doi.org/10.1292/jvms.14-0529
39 https://doi.org/10.1371/journal.pone.0016776
40 https://doi.org/10.1371/journal.pone.0075456
41 https://doi.org/10.20506/rst.19.2.1231
42 https://doi.org/10.2105/ajph.42.6.672
43 https://doi.org/10.7589/0090-3558-27.1.123
44 https://doi.org/10.7589/0090-3558-31.1.66
45 schema:datePublished 2017-10
46 schema:datePublishedReg 2017-10-01
47 schema:description Avian paramyxoviruses (APMVs) have been evaluated for their potential use as vaccine vectors, sparking research efforts leading to a better understanding of APMVs' replication and pathogenicity. However, within APMV serotypes, significant genetic diversity exists, and the infectivity of variant strains in mammals has not been studied. We utilized a mouse model to evaluate the pathogenicity of a variant strain of APMV-6 (APMV-6/red-necked stint/Japan/8KS0813/2008) in comparison with the prototype APMV-6 strain (APMV-6/duck/Hong Kong/18/199/1977). Although the two viruses differ substantially, both genetically and antigenically, we found that the variant and prototype strains could similarly replicate in respiratory tissues of infected mice and induce respiratory disease, sometimes resulting in death of the mice. Both viruses induced a humoral immune response that could be clearly detected by ELISA but which was poorly recognized by the hemagglutination inhibition test.
48 schema:genre research_article
49 schema:inLanguage en
50 schema:isAccessibleForFree false
51 schema:isPartOf N66fe47e1bd4f48a3ac56af1c9941d9d6
52 Nb38cd79abb49446fab9f6e2f89dd25d6
53 sg:journal.1083335
54 schema:name Evaluation of the replication and pathogenicity of a variant avian paramyxovirus serotype 6 in mice
55 schema:pagination 3035-3043
56 schema:productId N00f79d0ae1dc47d4bd6347b586c395fb
57 N2b09549ceb804ef5b44888b509593b86
58 N96fe5190af7040f9a5a71513ffba9b25
59 Nd3f465d733674bf1b682f24682654625
60 Nf408f38c6a4e446a8c7493ad473886b7
61 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090364169
62 https://doi.org/10.1007/s00705-017-3459-1
63 schema:sdDatePublished 2019-04-11T09:59
64 schema:sdLicense https://scigraph.springernature.com/explorer/license/
65 schema:sdPublisher Nf9849ab407f0441a963a69a13c017228
66 schema:url https://link.springer.com/10.1007%2Fs00705-017-3459-1
67 sgo:license sg:explorer/license/
68 sgo:sdDataset articles
69 rdf:type schema:ScholarlyArticle
70 N00f79d0ae1dc47d4bd6347b586c395fb schema:name pubmed_id
71 schema:value 28685285
72 rdf:type schema:PropertyValue
73 N01d54f86769b4ccfa58cb5ca17fdffaa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
74 schema:name Mice, Inbred BALB C
75 rdf:type schema:DefinedTerm
76 N1a4117afdf4241ceb166aa14365b67f7 rdf:first sg:person.0605647442.33
77 rdf:rest Nb39ce04c6bc44efea18d2c6045b6b953
78 N2487af8ca2f34e8fbab02b4eedd41001 rdf:first sg:person.0671511241.48
79 rdf:rest N6d4b31d5c3324924a1fdf8bb816e96d9
80 N2b09549ceb804ef5b44888b509593b86 schema:name readcube_id
81 schema:value 1587774dbd5bfab4c409268a4792a5b220dca794f56dab0350d59f63d5b3075b
82 rdf:type schema:PropertyValue
83 N39559968f91b4aa09dbab256dffc46dc rdf:first sg:person.01032425414.55
84 rdf:rest N6a66b958a2dd4cda91f987adc2371ec2
85 N4a0d3204ce814390ac21a12621889b52 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Mice
87 rdf:type schema:DefinedTerm
88 N55cacae7a11c4f828372da381b50f334 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Genetic Variation
90 rdf:type schema:DefinedTerm
91 N5f686637ea3e4e1fb33214944fc229dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Avulavirus
93 rdf:type schema:DefinedTerm
94 N66fe47e1bd4f48a3ac56af1c9941d9d6 schema:issueNumber 10
95 rdf:type schema:PublicationIssue
96 N6a66b958a2dd4cda91f987adc2371ec2 rdf:first sg:person.0757445370.63
97 rdf:rest N6d0c1078f3cb4cc381df3dbdb55708f5
98 N6d0c1078f3cb4cc381df3dbdb55708f5 rdf:first Na393daa10eeb4470988422b45ed322f0
99 rdf:rest N1a4117afdf4241ceb166aa14365b67f7
100 N6d4b31d5c3324924a1fdf8bb816e96d9 rdf:first sg:person.0623376041.99
101 rdf:rest rdf:nil
102 N8c5bb60e08d2428aae9ce4e101d54dd0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Male
104 rdf:type schema:DefinedTerm
105 N96fe5190af7040f9a5a71513ffba9b25 schema:name doi
106 schema:value 10.1007/s00705-017-3459-1
107 rdf:type schema:PropertyValue
108 Na393daa10eeb4470988422b45ed322f0 schema:affiliation https://www.grid.ac/institutes/grid.412310.5
109 schema:familyName Ozeki
110 schema:givenName Yuki
111 rdf:type schema:Person
112 Nb38cd79abb49446fab9f6e2f89dd25d6 schema:volumeNumber 162
113 rdf:type schema:PublicationVolume
114 Nb39ce04c6bc44efea18d2c6045b6b953 rdf:first sg:person.01137107407.33
115 rdf:rest N2487af8ca2f34e8fbab02b4eedd41001
116 Nbb4be555464645ca8aa2737b7764ddf5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Animals
118 rdf:type schema:DefinedTerm
119 Nc380bdc179b0423ba29c6aeb07106aaa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Serogroup
121 rdf:type schema:DefinedTerm
122 Nce66ca02689243e48c2dccc1774db9b0 rdf:first sg:person.01110615363.98
123 rdf:rest N39559968f91b4aa09dbab256dffc46dc
124 Nd271003cfc774c8b9d25a85c37617f48 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Virus Replication
126 rdf:type schema:DefinedTerm
127 Nd3f465d733674bf1b682f24682654625 schema:name nlm_unique_id
128 schema:value 7506870
129 rdf:type schema:PropertyValue
130 Nf408f38c6a4e446a8c7493ad473886b7 schema:name dimensions_id
131 schema:value pub.1090364169
132 rdf:type schema:PropertyValue
133 Nf599a470f68f47a29d7c65357771be8a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Female
135 rdf:type schema:DefinedTerm
136 Nf9849ab407f0441a963a69a13c017228 schema:name Springer Nature - SN SciGraph project
137 rdf:type schema:Organization
138 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
139 schema:name Medical and Health Sciences
140 rdf:type schema:DefinedTerm
141 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
142 schema:name Immunology
143 rdf:type schema:DefinedTerm
144 sg:grant.5977328 http://pending.schema.org/fundedItem sg:pub.10.1007/s00705-017-3459-1
145 rdf:type schema:MonetaryGrant
146 sg:journal.1083335 schema:issn 0304-8608
147 1432-8798
148 schema:name Archives of Virology
149 rdf:type schema:Periodical
150 sg:person.01032425414.55 schema:affiliation https://www.grid.ac/institutes/grid.419675.8
151 schema:familyName Trinh
152 schema:givenName Dai Quang
153 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01032425414.55
154 rdf:type schema:Person
155 sg:person.01110615363.98 schema:affiliation https://www.grid.ac/institutes/grid.419675.8
156 schema:familyName Bui
157 schema:givenName Vuong Nghia
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110615363.98
159 rdf:type schema:Person
160 sg:person.01137107407.33 schema:affiliation https://www.grid.ac/institutes/grid.416882.1
161 schema:familyName Nakamura
162 schema:givenName Kikuyasu
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01137107407.33
164 rdf:type schema:Person
165 sg:person.0605647442.33 schema:affiliation https://www.grid.ac/institutes/grid.116068.8
166 schema:familyName Runstadler
167 schema:givenName Jonathan
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605647442.33
169 rdf:type schema:Person
170 sg:person.0623376041.99 schema:affiliation https://www.grid.ac/institutes/grid.412310.5
171 schema:familyName Imai
172 schema:givenName Kunitoshi
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623376041.99
174 rdf:type schema:Person
175 sg:person.0671511241.48 schema:affiliation https://www.grid.ac/institutes/grid.412310.5
176 schema:familyName Ogawa
177 schema:givenName Haruko
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671511241.48
179 rdf:type schema:Person
180 sg:person.0757445370.63 schema:affiliation https://www.grid.ac/institutes/grid.412310.5
181 schema:familyName Abao
182 schema:givenName Lary N. B.
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757445370.63
184 rdf:type schema:Person
185 sg:pub.10.1007/978-1-59745-561-9_30 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013027638
186 https://doi.org/10.1007/978-1-59745-561-9_30
187 rdf:type schema:CreativeWork
188 sg:pub.10.1007/bf01310856 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025328943
189 https://doi.org/10.1007/bf01310856
190 rdf:type schema:CreativeWork
191 sg:pub.10.1007/s00705-013-1735-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040534165
192 https://doi.org/10.1007/s00705-013-1735-2
193 rdf:type schema:CreativeWork
194 sg:pub.10.1007/s00705-014-2162-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037307032
195 https://doi.org/10.1007/s00705-014-2162-8
196 rdf:type schema:CreativeWork
197 sg:pub.10.1007/s00705-016-2880-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011099812
198 https://doi.org/10.1007/s00705-016-2880-1
199 rdf:type schema:CreativeWork
200 sg:pub.10.1007/s11262-010-0479-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012527952
201 https://doi.org/10.1007/s11262-010-0479-2
202 rdf:type schema:CreativeWork
203 sg:pub.10.1186/1297-9716-42-38 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039147381
204 https://doi.org/10.1186/1297-9716-42-38
205 rdf:type schema:CreativeWork
206 https://app.dimensions.ai/details/publication/pub.1076885396 schema:CreativeWork
207 https://app.dimensions.ai/details/publication/pub.1077598305 schema:CreativeWork
208 https://doi.org/10.1006/viro.1993.1325 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004593326
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/j.meegid.2012.07.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036409460
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1016/j.micinf.2011.01.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043031753
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1016/j.virol.2011.11.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029474993
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1016/j.virusres.2009.12.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052839398
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1016/j.virusres.2010.02.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053680330
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1016/j.virusres.2010.06.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003949964
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1016/j.virusres.2016.11.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049194627
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1080/03079450802216645 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025008879
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1099/0022-1317-49-2-255 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060353619
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1099/0022-1317-67-3-427 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060355996
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1128/jvi.00822-10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024393192
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1128/jvi.00946-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030850666
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1128/jvi.01406-07 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045491259
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1136/vr.115.25-26.653 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062827435
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1155/2012/708216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043700037
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1292/jvms.14-0529 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025908110
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1371/journal.pone.0016776 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027224793
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1371/journal.pone.0075456 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041997531
245 rdf:type schema:CreativeWork
246 https://doi.org/10.20506/rst.19.2.1231 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068791751
247 rdf:type schema:CreativeWork
248 https://doi.org/10.2105/ajph.42.6.672 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068858310
249 rdf:type schema:CreativeWork
250 https://doi.org/10.7589/0090-3558-27.1.123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004410135
251 rdf:type schema:CreativeWork
252 https://doi.org/10.7589/0090-3558-31.1.66 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010781070
253 rdf:type schema:CreativeWork
254 https://www.grid.ac/institutes/grid.116068.8 schema:alternateName Massachusetts Institute of Technology
255 schema:name Massachusetts Institute of Technology, 02139, Cambridge, MA, USA
256 rdf:type schema:Organization
257 https://www.grid.ac/institutes/grid.412310.5 schema:alternateName Obihiro University of Agriculture and Veterinary Medicine
258 schema:name Department of Agriculture-Agribusiness and Marketing Assistance Service, 1101, Quezon City, Philippines
259 Diagnostic Center for Animal Health and Food Safety, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, 080-8555, Obihiro, Hokkaido, Japan
260 rdf:type schema:Organization
261 https://www.grid.ac/institutes/grid.416882.1 schema:alternateName National Institute of Animal Health
262 schema:name National Institute of Animal Health, 305-0856, Tsukuba, Ibaraki, Japan
263 rdf:type schema:Organization
264 https://www.grid.ac/institutes/grid.419675.8 schema:alternateName National Institute of Veterinary Research
265 schema:name Diagnostic Center for Animal Health and Food Safety, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, 080-8555, Obihiro, Hokkaido, Japan
266 National Institute of Veterinary Research, 86 Truong Chinh, Dong Da, Hanoi, Vietnam
267 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...