Calves are susceptible to infection with the newly emerged porcine deltacoronavirus, but not with the swine enteric alphacoronavirus, porcine epidemic ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-08

AUTHORS

Kwonil Jung, Hui Hu, Linda J. Saif

ABSTRACT

Fecal virus shedding, seroconversion and histopathology were evaluated in 3-7-year-old gnotobiotic calves orally inoculated with porcine deltacoronavirus (PDCoV) (9.0-9.6 log10 genomic equivalents [GE] of OH-FD22-P5; n=4) or porcine epidemic diarrhea virus (PEDV) (10.2-12.5 log10 GE of PC21A; n=3). In PDCoV-inoculated calves, an acute but persisting fecal viral RNA shedding and PDCoV-specific serum IgG antibody responses were observed, but without lesions or clinical disease. However, no fecal shedding, seroconversion, histological lesions, and clinical disease were detected in PEDV-inoculated calves. Our data indicate that calves are susceptible to infection by the newly emerged PDCoV, but not by the swine coronavirus, PEDV. More... »

PAGES

2357-2362

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00705-017-3351-z

DOI

http://dx.doi.org/10.1007/s00705-017-3351-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1084510794

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28374120


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