Non-targeted effects of virus-induced gene silencing vectors on host endogenous gene expression View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-09

AUTHORS

Enikő Oláh, Réka Pesti, Dénes Taller, Zoltán Havelda, Éva Várallyay

ABSTRACT

Virus-induced gene silencing (VIGS) uses recombinant viruses to study gene function; however, the effect of the virus vector itself on the gene expression of the host is not always considered. In our work, we investigated non-targeted gene expression changes of the host in order to see how often these changes appear. Effects of various VIGS vector infections were analysed by monitoring gene expression levels of housekeeping genes by Northern blot analysis in four different hosts. We found that non-targeted changes happens very often. More importantly, these non-targeted effects can cause drastic changes in the gene-expression pattern of host genes that are usually used as references in these studies. We have also found that in a tobacco rattle virus (TRV)-based VIGS, the presence of foreign sequences in the cloning site of the vector can also have a non-targeted effect, and even the use of an internal control can lead to unpredicted changes. Our results show that although VIGS is a very powerful technique, the VIGS vector, as a pathogen of the host, can cause unwanted changes in its gene-expression pattern, highlighting the importance of careful selection of both the genes to be tested and those to be used as references in the planned experiments. More... »

PAGES

2387-2393

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00705-016-2921-9

DOI

http://dx.doi.org/10.1007/s00705-016-2921-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1016862247

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27283101


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blotting, Northern", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cloning, Molecular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Regulation, Plant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Silencing", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plant Viruses", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plants", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Agricultural Biotechnology Institute", 
          "id": "https://www.grid.ac/institutes/grid.417744.5", 
          "name": [
            "Plant Developmental Biology and Diagnostics Groups, Agricultural Biotechnology Institute, National Agricultural Research and Innovation Centre, Szent-Gy\u00f6rgyi Albert utca 4., 100, G\u00f6d\u00f6ll\u0151, Hungary"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ol\u00e1h", 
        "givenName": "Enik\u0151", 
        "id": "sg:person.01347572777.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01347572777.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Agricultural Biotechnology Institute", 
          "id": "https://www.grid.ac/institutes/grid.417744.5", 
          "name": [
            "Plant Developmental Biology and Diagnostics Groups, Agricultural Biotechnology Institute, National Agricultural Research and Innovation Centre, Szent-Gy\u00f6rgyi Albert utca 4., 100, G\u00f6d\u00f6ll\u0151, Hungary"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pesti", 
        "givenName": "R\u00e9ka", 
        "id": "sg:person.01027076377.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027076377.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Agricultural Biotechnology Institute", 
          "id": "https://www.grid.ac/institutes/grid.417744.5", 
          "name": [
            "Plant Developmental Biology and Diagnostics Groups, Agricultural Biotechnology Institute, National Agricultural Research and Innovation Centre, Szent-Gy\u00f6rgyi Albert utca 4., 100, G\u00f6d\u00f6ll\u0151, Hungary"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Taller", 
        "givenName": "D\u00e9nes", 
        "id": "sg:person.015551513265.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015551513265.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Agricultural Biotechnology Institute", 
          "id": "https://www.grid.ac/institutes/grid.417744.5", 
          "name": [
            "Plant Developmental Biology and Diagnostics Groups, Agricultural Biotechnology Institute, National Agricultural Research and Innovation Centre, Szent-Gy\u00f6rgyi Albert utca 4., 100, G\u00f6d\u00f6ll\u0151, Hungary"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Havelda", 
        "givenName": "Zolt\u00e1n", 
        "id": "sg:person.01340260752.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340260752.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Agricultural Biotechnology Institute", 
          "id": "https://www.grid.ac/institutes/grid.417744.5", 
          "name": [
            "Plant Developmental Biology and Diagnostics Groups, Agricultural Biotechnology Institute, National Agricultural Research and Innovation Centre, Szent-Gy\u00f6rgyi Albert utca 4., 100, G\u00f6d\u00f6ll\u0151, Hungary"
          ], 
          "type": "Organization"
        }, 
        "familyName": "V\u00e1rallyay", 
        "givenName": "\u00c9va", 
        "id": "sg:person.0627464543.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627464543.13"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/978-1-62703-278-0_1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000975424", 
          "https://doi.org/10.1007/978-1-62703-278-0_1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jxb/ern305", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002225822"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.0960-7412.2000.00942.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005809835"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fpls.2014.00323", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006368557"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2006.04.140", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008087714"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-313x.2008.03501.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008133458"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0046451", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008531310"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-313x.2002.01291.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014294790"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.arplant.55.031903.141803", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015432055"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/viro.1998.9579", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015678942"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/viro.1998.9032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023643619"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.92.5.1679", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024115005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2229-10-146", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026497002", 
          "https://doi.org/10.1186/1471-2229-10-146"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.010366", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026815227"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0031263", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027711009"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.12.10.1975", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031066110"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-313x.1992.t01-24-00999.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033916714"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jbiotec.2013.08.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036983694"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2009/198680", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039486310"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/emboj.2008.88", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042648382"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00709-012-0421-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048951695", 
          "https://doi.org/10.1007/s00709-012-0421-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00709-012-0421-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048951695", 
          "https://doi.org/10.1007/s00709-012-0421-7"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-09", 
    "datePublishedReg": "2016-09-01", 
    "description": "Virus-induced gene silencing (VIGS) uses recombinant viruses to study gene function; however, the effect of the virus vector itself on the gene expression of the host is not always considered. In our work, we investigated non-targeted gene expression changes of the host in order to see how often these changes appear. Effects of various VIGS vector infections were analysed by monitoring gene expression levels of housekeeping genes by Northern blot analysis in four different hosts. We found that non-targeted changes happens very often. More importantly, these non-targeted effects can cause drastic changes in the gene-expression pattern of host genes that are usually used as references in these studies. We have also found that in a tobacco rattle virus (TRV)-based VIGS, the presence of foreign sequences in the cloning site of the vector can also have a non-targeted effect, and even the use of an internal control can lead to unpredicted changes. Our results show that although VIGS is a very powerful technique, the VIGS vector, as a pathogen of the host, can cause unwanted changes in its gene-expression pattern, highlighting the importance of careful selection of both the genes to be tested and those to be used as references in the planned experiments. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00705-016-2921-9", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.4187645", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.4191642", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1083335", 
        "issn": [
          "0304-8608", 
          "1432-8798"
        ], 
        "name": "Archives of Virology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "9", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "161"
      }
    ], 
    "name": "Non-targeted effects of virus-induced gene silencing vectors on host endogenous gene expression", 
    "pagination": "2387-2393", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "5057a09f02ab124319b3ababd42e949bd4eb0e7483ade87b1d6ae5d9688b37b4"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27283101"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7506870"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00705-016-2921-9"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1016862247"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00705-016-2921-9", 
      "https://app.dimensions.ai/details/publication/pub.1016862247"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:21", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000362_0000000362/records_87079_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs00705-016-2921-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00705-016-2921-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00705-016-2921-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00705-016-2921-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00705-016-2921-9'


 

This table displays all metadata directly associated to this object as RDF triples.

191 TRIPLES      21 PREDICATES      56 URIs      27 LITERALS      15 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00705-016-2921-9 schema:about N3075a42a92974c7aa33595f2f79e458a
2 N346200dbee1545d8835c783a435c0f8e
3 N37492c8749a046b7adb81bd5f943ca0d
4 N61a9d8b4831c44a2993258e29df61e3e
5 Nc2d0de7b927e47978a5525f3c15f3bc0
6 Nf78b7534d5914085903440739210edcf
7 anzsrc-for:06
8 anzsrc-for:0604
9 schema:author Ne9417650de824391b138a29e163f9f06
10 schema:citation sg:pub.10.1007/978-1-62703-278-0_1
11 sg:pub.10.1007/s00709-012-0421-7
12 sg:pub.10.1186/1471-2229-10-146
13 https://doi.org/10.1006/viro.1998.9032
14 https://doi.org/10.1006/viro.1998.9579
15 https://doi.org/10.1016/j.bbrc.2006.04.140
16 https://doi.org/10.1016/j.jbiotec.2013.08.008
17 https://doi.org/10.1038/emboj.2008.88
18 https://doi.org/10.1046/j.0960-7412.2000.00942.x
19 https://doi.org/10.1046/j.1365-313x.1992.t01-24-00999.x
20 https://doi.org/10.1046/j.1365-313x.2002.01291.x
21 https://doi.org/10.1073/pnas.92.5.1679
22 https://doi.org/10.1093/jxb/ern305
23 https://doi.org/10.1105/tpc.010366
24 https://doi.org/10.1105/tpc.12.10.1975
25 https://doi.org/10.1111/j.1365-313x.2008.03501.x
26 https://doi.org/10.1146/annurev.arplant.55.031903.141803
27 https://doi.org/10.1155/2009/198680
28 https://doi.org/10.1371/journal.pone.0031263
29 https://doi.org/10.1371/journal.pone.0046451
30 https://doi.org/10.3389/fpls.2014.00323
31 schema:datePublished 2016-09
32 schema:datePublishedReg 2016-09-01
33 schema:description Virus-induced gene silencing (VIGS) uses recombinant viruses to study gene function; however, the effect of the virus vector itself on the gene expression of the host is not always considered. In our work, we investigated non-targeted gene expression changes of the host in order to see how often these changes appear. Effects of various VIGS vector infections were analysed by monitoring gene expression levels of housekeeping genes by Northern blot analysis in four different hosts. We found that non-targeted changes happens very often. More importantly, these non-targeted effects can cause drastic changes in the gene-expression pattern of host genes that are usually used as references in these studies. We have also found that in a tobacco rattle virus (TRV)-based VIGS, the presence of foreign sequences in the cloning site of the vector can also have a non-targeted effect, and even the use of an internal control can lead to unpredicted changes. Our results show that although VIGS is a very powerful technique, the VIGS vector, as a pathogen of the host, can cause unwanted changes in its gene-expression pattern, highlighting the importance of careful selection of both the genes to be tested and those to be used as references in the planned experiments.
34 schema:genre research_article
35 schema:inLanguage en
36 schema:isAccessibleForFree false
37 schema:isPartOf N61c002fb869645659f8e458a0651199b
38 Nf50536625a174fbdbe3317d334b8e615
39 sg:journal.1083335
40 schema:name Non-targeted effects of virus-induced gene silencing vectors on host endogenous gene expression
41 schema:pagination 2387-2393
42 schema:productId N1579e3b812a342d69f0f6a4b1c246399
43 N16b399e9cf894991944096c8c11988d9
44 N18c51dc34488417494f1269db27df886
45 N555e9f2605cb4d62afd53c70d7e89bb7
46 Na9428cbd452f4cbeb28fa3583fc398b0
47 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016862247
48 https://doi.org/10.1007/s00705-016-2921-9
49 schema:sdDatePublished 2019-04-11T12:21
50 schema:sdLicense https://scigraph.springernature.com/explorer/license/
51 schema:sdPublisher N29ca1a179597445a8319533c3a3c5341
52 schema:url https://link.springer.com/10.1007%2Fs00705-016-2921-9
53 sgo:license sg:explorer/license/
54 sgo:sdDataset articles
55 rdf:type schema:ScholarlyArticle
56 N04fb6e1e17554e0ea8f0dfcf7b5d78ab rdf:first sg:person.01340260752.59
57 rdf:rest Na1dccf21311f4edbbde698f54511e907
58 N1579e3b812a342d69f0f6a4b1c246399 schema:name doi
59 schema:value 10.1007/s00705-016-2921-9
60 rdf:type schema:PropertyValue
61 N16b399e9cf894991944096c8c11988d9 schema:name dimensions_id
62 schema:value pub.1016862247
63 rdf:type schema:PropertyValue
64 N18c51dc34488417494f1269db27df886 schema:name pubmed_id
65 schema:value 27283101
66 rdf:type schema:PropertyValue
67 N29ca1a179597445a8319533c3a3c5341 schema:name Springer Nature - SN SciGraph project
68 rdf:type schema:Organization
69 N3075a42a92974c7aa33595f2f79e458a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
70 schema:name Gene Expression Regulation, Plant
71 rdf:type schema:DefinedTerm
72 N346200dbee1545d8835c783a435c0f8e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Plants
74 rdf:type schema:DefinedTerm
75 N37492c8749a046b7adb81bd5f943ca0d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Plant Viruses
77 rdf:type schema:DefinedTerm
78 N555e9f2605cb4d62afd53c70d7e89bb7 schema:name readcube_id
79 schema:value 5057a09f02ab124319b3ababd42e949bd4eb0e7483ade87b1d6ae5d9688b37b4
80 rdf:type schema:PropertyValue
81 N59c22d48ed774519bfebfbf26421549c rdf:first sg:person.01027076377.10
82 rdf:rest Na110521b51b84c9b977f437315b67cc2
83 N61a9d8b4831c44a2993258e29df61e3e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Cloning, Molecular
85 rdf:type schema:DefinedTerm
86 N61c002fb869645659f8e458a0651199b schema:issueNumber 9
87 rdf:type schema:PublicationIssue
88 Na110521b51b84c9b977f437315b67cc2 rdf:first sg:person.015551513265.50
89 rdf:rest N04fb6e1e17554e0ea8f0dfcf7b5d78ab
90 Na1dccf21311f4edbbde698f54511e907 rdf:first sg:person.0627464543.13
91 rdf:rest rdf:nil
92 Na9428cbd452f4cbeb28fa3583fc398b0 schema:name nlm_unique_id
93 schema:value 7506870
94 rdf:type schema:PropertyValue
95 Nc2d0de7b927e47978a5525f3c15f3bc0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Blotting, Northern
97 rdf:type schema:DefinedTerm
98 Ne9417650de824391b138a29e163f9f06 rdf:first sg:person.01347572777.33
99 rdf:rest N59c22d48ed774519bfebfbf26421549c
100 Nf50536625a174fbdbe3317d334b8e615 schema:volumeNumber 161
101 rdf:type schema:PublicationVolume
102 Nf78b7534d5914085903440739210edcf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Gene Silencing
104 rdf:type schema:DefinedTerm
105 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
106 schema:name Biological Sciences
107 rdf:type schema:DefinedTerm
108 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
109 schema:name Genetics
110 rdf:type schema:DefinedTerm
111 sg:grant.4187645 http://pending.schema.org/fundedItem sg:pub.10.1007/s00705-016-2921-9
112 rdf:type schema:MonetaryGrant
113 sg:grant.4191642 http://pending.schema.org/fundedItem sg:pub.10.1007/s00705-016-2921-9
114 rdf:type schema:MonetaryGrant
115 sg:journal.1083335 schema:issn 0304-8608
116 1432-8798
117 schema:name Archives of Virology
118 rdf:type schema:Periodical
119 sg:person.01027076377.10 schema:affiliation https://www.grid.ac/institutes/grid.417744.5
120 schema:familyName Pesti
121 schema:givenName Réka
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027076377.10
123 rdf:type schema:Person
124 sg:person.01340260752.59 schema:affiliation https://www.grid.ac/institutes/grid.417744.5
125 schema:familyName Havelda
126 schema:givenName Zoltán
127 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340260752.59
128 rdf:type schema:Person
129 sg:person.01347572777.33 schema:affiliation https://www.grid.ac/institutes/grid.417744.5
130 schema:familyName Oláh
131 schema:givenName Enikő
132 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01347572777.33
133 rdf:type schema:Person
134 sg:person.015551513265.50 schema:affiliation https://www.grid.ac/institutes/grid.417744.5
135 schema:familyName Taller
136 schema:givenName Dénes
137 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015551513265.50
138 rdf:type schema:Person
139 sg:person.0627464543.13 schema:affiliation https://www.grid.ac/institutes/grid.417744.5
140 schema:familyName Várallyay
141 schema:givenName Éva
142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627464543.13
143 rdf:type schema:Person
144 sg:pub.10.1007/978-1-62703-278-0_1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000975424
145 https://doi.org/10.1007/978-1-62703-278-0_1
146 rdf:type schema:CreativeWork
147 sg:pub.10.1007/s00709-012-0421-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048951695
148 https://doi.org/10.1007/s00709-012-0421-7
149 rdf:type schema:CreativeWork
150 sg:pub.10.1186/1471-2229-10-146 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026497002
151 https://doi.org/10.1186/1471-2229-10-146
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1006/viro.1998.9032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023643619
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1006/viro.1998.9579 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015678942
156 rdf:type schema:CreativeWork
157 https://doi.org/10.1016/j.bbrc.2006.04.140 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008087714
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1016/j.jbiotec.2013.08.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036983694
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1038/emboj.2008.88 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042648382
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1046/j.0960-7412.2000.00942.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1005809835
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1046/j.1365-313x.1992.t01-24-00999.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033916714
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1046/j.1365-313x.2002.01291.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014294790
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1073/pnas.92.5.1679 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024115005
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1093/jxb/ern305 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002225822
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1105/tpc.010366 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026815227
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1105/tpc.12.10.1975 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031066110
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1111/j.1365-313x.2008.03501.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1008133458
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1146/annurev.arplant.55.031903.141803 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015432055
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1155/2009/198680 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039486310
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1371/journal.pone.0031263 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027711009
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1371/journal.pone.0046451 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008531310
186 rdf:type schema:CreativeWork
187 https://doi.org/10.3389/fpls.2014.00323 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006368557
188 rdf:type schema:CreativeWork
189 https://www.grid.ac/institutes/grid.417744.5 schema:alternateName Agricultural Biotechnology Institute
190 schema:name Plant Developmental Biology and Diagnostics Groups, Agricultural Biotechnology Institute, National Agricultural Research and Innovation Centre, Szent-Györgyi Albert utca 4., 100, Gödöllő, Hungary
191 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...