Ontology type: schema:ScholarlyArticle
2019-01
AUTHORSJ. M. Menchón, J. Espadaler, M. Tuson, J. Saiz-Ruiz, J. Bobes, E. Vieta, E. Álvarez, V. Pérez
ABSTRACTClinical utility of commercial multi-gene pharmacogenetic tests in depression is starting to be studied with some promising results on efficacy and tolerability. Among the next steps is the definition of the patient profile that is most likely to benefit from testing. Here we present a reanalysis of data from the AB-GEN randomized clinical trial showing that clinical utility of pharmacogenetic testing can be markedly influenced by patient characteristics such as age, baseline severity and duration of current depressive episode.Trial registration ClinicalTrials.gov NCT02529462. More... »
PAGES95-99
http://scigraph.springernature.com/pub.10.1007/s00702-018-1879-z
DOIhttp://dx.doi.org/10.1007/s00702-018-1879-z
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1103816284
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/29728861
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "University of Barcelona",
"id": "https://www.grid.ac/institutes/grid.5841.8",
"name": [
"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM), Madrid, Spain",
"Departament de Psiquiatria, Hospital Universitari de Bellvitge, Institut d\u2019Investigaci\u00f3 Biom\u00e8dica de Bellvitge (IDIBELL), Barcelona, Spain",
"Departament de Ci\u00e8ncies Cl\u00edniques, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Mench\u00f3n",
"givenName": "J. M.",
"id": "sg:person.01134335452.49",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01134335452.49"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "AB-Biotics (Spain)",
"id": "https://www.grid.ac/institutes/grid.476011.5",
"name": [
"AB-Biotics SA, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Espadaler",
"givenName": "J.",
"id": "sg:person.01372546321.00",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372546321.00"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "AB-Biotics (Spain)",
"id": "https://www.grid.ac/institutes/grid.476011.5",
"name": [
"AB-Biotics SA, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Tuson",
"givenName": "M.",
"id": "sg:person.01266555261.21",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266555261.21"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital Universitario Ram\u00f3n y Cajal",
"id": "https://www.grid.ac/institutes/grid.411347.4",
"name": [
"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM), Madrid, Spain",
"Departamento de Psiquiatr\u00eda, Instituto Ram\u00f3n y Cajal de Investigaci\u00f3n Sanitaria (IRYCIS), Hospital Universitario Ram\u00f3n y Cajal, Universidad de Alcal\u00e1, Madrid, Spain"
],
"type": "Organization"
},
"familyName": "Saiz-Ruiz",
"givenName": "J.",
"id": "sg:person.01017210777.39",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017210777.39"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Oviedo",
"id": "https://www.grid.ac/institutes/grid.10863.3c",
"name": [
"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM), Madrid, Spain",
"\u00c1rea de Psiquiatr\u00eda, Facultad de Medicina, Universidad de Oviedo, Oviedo, Spain",
"Instituto Universitario de Neurociencias del Principado de Asturias (INEUROPA), Oviedo, Spain"
],
"type": "Organization"
},
"familyName": "Bobes",
"givenName": "J.",
"id": "sg:person.0662502720.69",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0662502720.69"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Barcelona",
"id": "https://www.grid.ac/institutes/grid.5841.8",
"name": [
"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM), Madrid, Spain",
"Institut Cl\u00ednic de Neuroci\u00e8ncies, Hospital Cl\u00ednic de Barcelona, Universitat de Barcelona, Barcelona, Spain",
"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Vieta",
"givenName": "E.",
"id": "sg:person.01247375326.31",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247375326.31"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Autonomous University of Barcelona",
"id": "https://www.grid.ac/institutes/grid.7080.f",
"name": [
"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM), Madrid, Spain",
"Servei de Psiquiatria, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain",
"Institut d\u2019Investigaci\u00f3 Biom\u00e8dica Sant Pau, Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "\u00c1lvarez",
"givenName": "E.",
"id": "sg:person.07406201322.48",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07406201322.48"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental",
"id": "https://www.grid.ac/institutes/grid.469673.9",
"name": [
"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM), Madrid, Spain",
"Institut de Neuropsiquiatria i Addiccions (INAD), Hospital del Mar, Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "P\u00e9rez",
"givenName": "V.",
"id": "sg:person.01275026332.91",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01275026332.91"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1001/jama.2009.1943",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006143548"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/yco.0000000000000023",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010091113"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/yco.0000000000000023",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010091113"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/yco.0000000000000023",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010091113"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0140-6736(09)60046-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013725061"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.biopsych.2012.10.030",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023812919"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1159/000430915",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023902995"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jad.2016.06.013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034339938"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jad.2016.06.013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034339938"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s2215-0366(16)00017-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034558611"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.9758/cpn.2015.13.2.150",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035775048"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/jnnp.23.1.56",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042824373"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.2165/00023210-200822110-00005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050104267",
"https://doi.org/10.2165/00023210-200822110-00005"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1176/ajp.2006.163.11.1905",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1063486269"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1176/appi.ajp.2008.08071027",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1063498340"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.4088/jcp.10r06531",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1072205104"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12888-017-1412-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1090661790",
"https://doi.org/10.1186/s12888-017-1412-1"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12888-017-1412-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1090661790",
"https://doi.org/10.1186/s12888-017-1412-1"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jpsychires.2017.09.024",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1091906178"
],
"type": "CreativeWork"
}
],
"datePublished": "2019-01",
"datePublishedReg": "2019-01-01",
"description": "Clinical utility of commercial multi-gene pharmacogenetic tests in depression is starting to be studied with some promising results on efficacy and tolerability. Among the next steps is the definition of the patient profile that is most likely to benefit from testing. Here we present a reanalysis of data from the AB-GEN randomized clinical trial showing that clinical utility of pharmacogenetic testing can be markedly influenced by patient characteristics such as age, baseline severity and duration of current depressive episode.Trial registration ClinicalTrials.gov NCT02529462.",
"genre": "research_article",
"id": "sg:pub.10.1007/s00702-018-1879-z",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1312227",
"issn": [
"0300-9564",
"1435-1463"
],
"name": "Journal of Neural Transmission",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "126"
}
],
"name": "Patient characteristics driving clinical utility in psychiatric pharmacogenetics: a reanalysis from the AB-GEN multicentric trial",
"pagination": "95-99",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"eecdedc60ed0a80ac3ab666679e03f1f4009bc8b22d3071a69a4dc38600e0cd1"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"29728861"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"9702341"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s00702-018-1879-z"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1103816284"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s00702-018-1879-z",
"https://app.dimensions.ai/details/publication/pub.1103816284"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T12:54",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000364_0000000364/records_72867_00000001.jsonl",
"type": "ScholarlyArticle",
"url": "https://link.springer.com/10.1007%2Fs00702-018-1879-z"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00702-018-1879-z'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00702-018-1879-z'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00702-018-1879-z'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00702-018-1879-z'
This table displays all metadata directly associated to this object as RDF triples.
190 TRIPLES
21 PREDICATES
44 URIs
21 LITERALS
9 BLANK NODES