Influence of brain-derived neurotrophic-factor and apolipoprotein E genetic variants on hippocampal volume and memory performance in healthy young adults View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-02

AUTHORS

Tanja Richter-Schmidinger, Panagiotis Alexopoulos, Marco Horn, Sebastian Maus, Martin Reichel, Cosima Rhein, Piotr Lewczuk, Christos Sidiropoulos, Thomas Kneib, Robert Perneczky, Arnd Doerfler, Johannes Kornhuber

ABSTRACT

Unravelling the impact of genetic variants on clinical phenotypes is a challenging task. Apolipoprotein E (ApoE) and brain-derived neurotrophic factor (BDNF) play an important role in cell growth, regeneration, synaptic plasticity, learning and memory processes. The aim of the present study was to examine the impact of BDNF Val66Met- and ApoE-polymorphisms and their interactions on hippocampal morphology and memory functions in healthy young adults. Hippocampal volume and memory performance of 135 healthy individuals, aged 24.6 ± 3.2 years, were assessed, using magnetic resonance imaging and the Inventory for Memory diagnostics. The performance of BDNF-Met66 carriers was significantly lower in working memory (P = 0.03) compared with non carriers, whereas no further differences were observed either in cognitive performance or in hippocampal volumes between the groups. Age, BDNF Val66 Met polymorphism and the interaction factor BDNF genotype x age were significantly associated with the variation of working memory scores (P = 0.01, 0.01, 0.02 respectively). No statistically significant differences were detected in the volumes of hippocampi and in memory phenotypes between individuals carrying the ApoE E4 allele and those without it. The analysis did not reveal an impact of gene-gene interaction between BDNF and ApoE genes on hippocampal volumes or memory performance. BDNF Val66Met polymorphism seems to influence working memory function and modulate the effects of ageing on working memory in healthy young adults. More... »

PAGES

249-257

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00702-010-0539-8

DOI

http://dx.doi.org/10.1007/s00702-010-0539-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1051269234

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21190051


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1701", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Psychology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/17", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Psychology and Cognitive Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Apolipoproteins E", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Brain-Derived Neurotrophic Factor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Predisposition to Disease", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hippocampus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Memory", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymorphism, Single Nucleotide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Erlangen-Nuremberg", 
          "id": "https://www.grid.ac/institutes/grid.5330.5", 
          "name": [
            "Department of Psychiatry and Psychotherapy, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Richter-Schmidinger", 
        "givenName": "Tanja", 
        "id": "sg:person.01061442307.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01061442307.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Rechts der Isar Hospital", 
          "id": "https://www.grid.ac/institutes/grid.15474.33", 
          "name": [
            "Department of Psychiatry and Psychotherapy, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany", 
            "Department of Psychiatry and Psychotherapy, Technische Universit\u00e4t M\u00fcnchen, Ismaninger Str. 22, 81675, Munich, Germany", 
            "Klinik f\u00fcr Psychiatrie und Psychotherapie, Klinikum rechts der Isar der Technischen Universit\u00e4t M\u00fcnchen, Ismaninger Str. 22, 81675, Munich, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Alexopoulos", 
        "givenName": "Panagiotis", 
        "id": "sg:person.01115350015.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115350015.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Erlangen-Nuremberg", 
          "id": "https://www.grid.ac/institutes/grid.5330.5", 
          "name": [
            "Department of Psychiatry and Psychotherapy, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Horn", 
        "givenName": "Marco", 
        "id": "sg:person.01335531003.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335531003.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Erlangen-Nuremberg", 
          "id": "https://www.grid.ac/institutes/grid.5330.5", 
          "name": [
            "Department of Psychiatry and Psychotherapy, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maus", 
        "givenName": "Sebastian", 
        "id": "sg:person.0660240103.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660240103.66"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Erlangen-Nuremberg", 
          "id": "https://www.grid.ac/institutes/grid.5330.5", 
          "name": [
            "Department of Psychiatry and Psychotherapy, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Reichel", 
        "givenName": "Martin", 
        "id": "sg:person.0730513364.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730513364.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Erlangen-Nuremberg", 
          "id": "https://www.grid.ac/institutes/grid.5330.5", 
          "name": [
            "Department of Psychiatry and Psychotherapy, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rhein", 
        "givenName": "Cosima", 
        "id": "sg:person.01324776247.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01324776247.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Erlangen-Nuremberg", 
          "id": "https://www.grid.ac/institutes/grid.5330.5", 
          "name": [
            "Department of Psychiatry and Psychotherapy, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lewczuk", 
        "givenName": "Piotr", 
        "id": "sg:person.0757224165.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757224165.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Henry Ford Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413103.4", 
          "name": [
            "Department of Psychiatry and Psychotherapy, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany", 
            "Department of Neurology, Henry Ford Hospital, Detroit, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sidiropoulos", 
        "givenName": "Christos", 
        "id": "sg:person.0772561771.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772561771.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Carl von Ossietzky University of Oldenburg", 
          "id": "https://www.grid.ac/institutes/grid.5560.6", 
          "name": [
            "Institute of Mathematics, Carl von Ossietzky Universit\u00e4t Oldenburg, Oldenburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kneib", 
        "givenName": "Thomas", 
        "id": "sg:person.01272020411.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272020411.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Technical University Munich", 
          "id": "https://www.grid.ac/institutes/grid.6936.a", 
          "name": [
            "Department of Psychiatry and Psychotherapy, Technische Universit\u00e4t M\u00fcnchen, Ismaninger Str. 22, 81675, Munich, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Perneczky", 
        "givenName": "Robert", 
        "id": "sg:person.0757536766.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757536766.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Erlangen-Nuremberg", 
          "id": "https://www.grid.ac/institutes/grid.5330.5", 
          "name": [
            "Department of Neuroradiology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Doerfler", 
        "givenName": "Arnd", 
        "id": "sg:person.01237357563.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237357563.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Erlangen-Nuremberg", 
          "id": "https://www.grid.ac/institutes/grid.5330.5", 
          "name": [
            "Department of Psychiatry and Psychotherapy, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kornhuber", 
        "givenName": "Johannes", 
        "id": "sg:person.01105723234.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105723234.32"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1111/j.1601-183x.2008.00409.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000275669"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/mp.2008.32", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000526104", 
          "https://doi.org/10.1038/mp.2008.32"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neulet.2005.11.067", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000684572"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1096/fj.02-0143fje", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003576335"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neurobiolaging.2004.01.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003671521"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1098-1063(2000)10:6<752::aid-hipo1012>3.0.co;2-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004354224"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/npp.2009.214", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005944548", 
          "https://doi.org/10.1038/npp.2009.214"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0900345106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006130429"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.mp.4001656", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006268120", 
          "https://doi.org/10.1038/sj.mp.4001656"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.mp.4001656", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006268120", 
          "https://doi.org/10.1038/sj.mp.4001656"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0079-6123(00)28020-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006377329"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.4454-03.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007174324"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archpsyc.63.7.731", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008183898"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajmg.b.30150", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009418817"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1471-4159.1996.67031124.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009677225"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.25.21.9259-9268.2005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010667349"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archneur.1994.00540210046012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012369119"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroimage.2004.10.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014028205"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.2680-04.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014563730"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biopsych.2005.09.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015808175"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/cercor/bhl103", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015949524"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0500579102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016735939"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12031-009-9205-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017027097", 
          "https://doi.org/10.1007/s12031-009-9205-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12031-009-9205-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017027097", 
          "https://doi.org/10.1007/s12031-009-9205-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroimage.2009.01.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024447379"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hipo.20294", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026127527"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hipo.20294", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026127527"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neurobiolaging.2006.12.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029096702"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/pdr.0b013e3181cb8e68", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029390202", 
          "https://doi.org/10.1203/pdr.0b013e3181cb8e68"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/pdr.0b013e3181cb8e68", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029390202", 
          "https://doi.org/10.1203/pdr.0b013e3181cb8e68"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1601-183x.2006.00254.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034853760"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.modgep.2006.03.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035012184"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ana.410380122", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037096655"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1474-4422(07)70106-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037182752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0304-3940(00)01569-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038885666"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0197-4580(00)00150-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040597555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/00207450802325843", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042189772"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neulet.2004.06.039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047494062"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jnnp.2004.053645", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048192118"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jnnp.71.3.340", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049286775"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00223534", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050315234", 
          "https://doi.org/10.1007/bf00223534"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35049004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050450113", 
          "https://doi.org/10.1038/35049004"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35049004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050450113", 
          "https://doi.org/10.1038/35049004"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.0046-08.2008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050955809"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroimage.2010.01.058", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053252226"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(03)00035-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053304729"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2006-953127", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057468508"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1176/ajp.2007.164.6.916", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063486903"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/01.wnl.0000148478.39691.d3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064346662"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/01.wnl.0000148478.39691.d3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064346662"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/01.wnl.0000148478.39691.d3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064346662"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/wnl.0b013e3181a2e8d0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064354303"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/wnl.0b013e3181a2e8d0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064354303"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/wnl.0b013e3181a2e8d0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064354303"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/jn.1999.82.6.3196", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074564095"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.20-18-07116.2000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074700597"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.23-17-06690.2003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1075324294"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078691240", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082015936", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082015938", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.13-10-04146.1993", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082642333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.18-17-06830.1998", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083308481"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2011-02", 
    "datePublishedReg": "2011-02-01", 
    "description": "Unravelling the impact of genetic variants on clinical phenotypes is a challenging task. Apolipoprotein E (ApoE) and brain-derived neurotrophic factor (BDNF) play an important role in cell growth, regeneration, synaptic plasticity, learning and memory processes. The aim of the present study was to examine the impact of BDNF Val66Met- and ApoE-polymorphisms and their interactions on hippocampal morphology and memory functions in healthy young adults. Hippocampal volume and memory performance of 135 healthy individuals, aged 24.6 \u00b1 3.2 years, were assessed, using magnetic resonance imaging and the Inventory for Memory diagnostics. The performance of BDNF-Met66 carriers was significantly lower in working memory (P = 0.03) compared with non carriers, whereas no further differences were observed either in cognitive performance or in hippocampal volumes between the groups. Age, BDNF Val66 Met polymorphism and the interaction factor BDNF genotype x age were significantly associated with the variation of working memory scores (P = 0.01, 0.01, 0.02 respectively). No statistically significant differences were detected in the volumes of hippocampi and in memory phenotypes between individuals carrying the ApoE E4 allele and those without it. The analysis did not reveal an impact of gene-gene interaction between BDNF and ApoE genes on hippocampal volumes or memory performance. BDNF Val66Met polymorphism seems to influence working memory function and modulate the effects of ageing on working memory in healthy young adults.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00702-010-0539-8", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1312227", 
        "issn": [
          "0300-9564", 
          "1435-1463"
        ], 
        "name": "Journal of Neural Transmission", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "118"
      }
    ], 
    "name": "Influence of brain-derived neurotrophic-factor and apolipoprotein E genetic variants on hippocampal volume and memory performance in healthy young adults", 
    "pagination": "249-257", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "f439a1730f8132fa4258f8cb53dd65d4dda43d9f9af16fbcf79bbe725087e8a5"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "21190051"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9702341"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00702-010-0539-8"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1051269234"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00702-010-0539-8", 
      "https://app.dimensions.ai/details/publication/pub.1051269234"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T21:30", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8687_00000483.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s00702-010-0539-8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00702-010-0539-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00702-010-0539-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00702-010-0539-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00702-010-0539-8'


 

This table displays all metadata directly associated to this object as RDF triples.

369 TRIPLES      21 PREDICATES      93 URIs      32 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00702-010-0539-8 schema:about N24cd29458f484f5491cdce51f5c9520c
2 N2a27ecfe0c1c4eaba0617d51615aff4a
3 N39d8ab7930da4d938122cef320ae81b9
4 N4c7b07f16072439f988a4068c8116cd2
5 N4d89efa58d674793b2ac76c58e1e8b4f
6 N4ea422f2b80f49e29e59fca9fbce476e
7 N512d8345084f42b99d2e7e4dbe02004d
8 N8ae8cc920a4242eab0ced2088f9300e2
9 Nb6b0814e98f44ec6847679817461786f
10 Ndfbab40f86cc48a9916c264f8aeb35f6
11 Nfb2de789c4644b8386415d75fba2f42b
12 anzsrc-for:17
13 anzsrc-for:1701
14 schema:author N923432a3409d4bb0a53455d1ea10cf8d
15 schema:citation sg:pub.10.1007/bf00223534
16 sg:pub.10.1007/s12031-009-9205-8
17 sg:pub.10.1038/35049004
18 sg:pub.10.1038/mp.2008.32
19 sg:pub.10.1038/npp.2009.214
20 sg:pub.10.1038/sj.mp.4001656
21 sg:pub.10.1203/pdr.0b013e3181cb8e68
22 https://app.dimensions.ai/details/publication/pub.1078691240
23 https://app.dimensions.ai/details/publication/pub.1082015936
24 https://app.dimensions.ai/details/publication/pub.1082015938
25 https://doi.org/10.1001/archneur.1994.00540210046012
26 https://doi.org/10.1001/archpsyc.63.7.731
27 https://doi.org/10.1002/1098-1063(2000)10:6<752::aid-hipo1012>3.0.co;2-y
28 https://doi.org/10.1002/ajmg.b.30150
29 https://doi.org/10.1002/ana.410380122
30 https://doi.org/10.1002/hipo.20294
31 https://doi.org/10.1016/j.biopsych.2005.09.022
32 https://doi.org/10.1016/j.modgep.2006.03.009
33 https://doi.org/10.1016/j.neulet.2004.06.039
34 https://doi.org/10.1016/j.neulet.2005.11.067
35 https://doi.org/10.1016/j.neurobiolaging.2004.01.003
36 https://doi.org/10.1016/j.neurobiolaging.2006.12.010
37 https://doi.org/10.1016/j.neuroimage.2004.10.016
38 https://doi.org/10.1016/j.neuroimage.2009.01.009
39 https://doi.org/10.1016/j.neuroimage.2010.01.058
40 https://doi.org/10.1016/s0079-6123(00)28020-5
41 https://doi.org/10.1016/s0092-8674(03)00035-7
42 https://doi.org/10.1016/s0197-4580(00)00150-0
43 https://doi.org/10.1016/s0304-3940(00)01569-x
44 https://doi.org/10.1016/s1474-4422(07)70106-0
45 https://doi.org/10.1046/j.1471-4159.1996.67031124.x
46 https://doi.org/10.1055/s-2006-953127
47 https://doi.org/10.1073/pnas.0500579102
48 https://doi.org/10.1073/pnas.0900345106
49 https://doi.org/10.1080/00207450802325843
50 https://doi.org/10.1093/cercor/bhl103
51 https://doi.org/10.1096/fj.02-0143fje
52 https://doi.org/10.1111/j.1601-183x.2006.00254.x
53 https://doi.org/10.1111/j.1601-183x.2008.00409.x
54 https://doi.org/10.1128/mcb.25.21.9259-9268.2005
55 https://doi.org/10.1136/jnnp.2004.053645
56 https://doi.org/10.1136/jnnp.71.3.340
57 https://doi.org/10.1152/jn.1999.82.6.3196
58 https://doi.org/10.1176/ajp.2007.164.6.916
59 https://doi.org/10.1212/01.wnl.0000148478.39691.d3
60 https://doi.org/10.1212/wnl.0b013e3181a2e8d0
61 https://doi.org/10.1523/jneurosci.0046-08.2008
62 https://doi.org/10.1523/jneurosci.13-10-04146.1993
63 https://doi.org/10.1523/jneurosci.18-17-06830.1998
64 https://doi.org/10.1523/jneurosci.20-18-07116.2000
65 https://doi.org/10.1523/jneurosci.23-17-06690.2003
66 https://doi.org/10.1523/jneurosci.2680-04.2004
67 https://doi.org/10.1523/jneurosci.4454-03.2004
68 schema:datePublished 2011-02
69 schema:datePublishedReg 2011-02-01
70 schema:description Unravelling the impact of genetic variants on clinical phenotypes is a challenging task. Apolipoprotein E (ApoE) and brain-derived neurotrophic factor (BDNF) play an important role in cell growth, regeneration, synaptic plasticity, learning and memory processes. The aim of the present study was to examine the impact of BDNF Val66Met- and ApoE-polymorphisms and their interactions on hippocampal morphology and memory functions in healthy young adults. Hippocampal volume and memory performance of 135 healthy individuals, aged 24.6 ± 3.2 years, were assessed, using magnetic resonance imaging and the Inventory for Memory diagnostics. The performance of BDNF-Met66 carriers was significantly lower in working memory (P = 0.03) compared with non carriers, whereas no further differences were observed either in cognitive performance or in hippocampal volumes between the groups. Age, BDNF Val66 Met polymorphism and the interaction factor BDNF genotype x age were significantly associated with the variation of working memory scores (P = 0.01, 0.01, 0.02 respectively). No statistically significant differences were detected in the volumes of hippocampi and in memory phenotypes between individuals carrying the ApoE E4 allele and those without it. The analysis did not reveal an impact of gene-gene interaction between BDNF and ApoE genes on hippocampal volumes or memory performance. BDNF Val66Met polymorphism seems to influence working memory function and modulate the effects of ageing on working memory in healthy young adults.
71 schema:genre research_article
72 schema:inLanguage en
73 schema:isAccessibleForFree false
74 schema:isPartOf N93942af4aa0b4b31afa00d6f1299ce13
75 Nf8a2404ec06041c5bd2e357d1c32c96f
76 sg:journal.1312227
77 schema:name Influence of brain-derived neurotrophic-factor and apolipoprotein E genetic variants on hippocampal volume and memory performance in healthy young adults
78 schema:pagination 249-257
79 schema:productId N31cda6a771374f83a04fc1bde1bcaea5
80 N65a4b0f445b148c3a03f3390e9a553ee
81 N6d8c231a87994097b6e7b28819291058
82 N84a185d25e8142539e1f4164d082561f
83 Na6c1743a0d3d4ebeaa166456b02e3a42
84 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051269234
85 https://doi.org/10.1007/s00702-010-0539-8
86 schema:sdDatePublished 2019-04-10T21:30
87 schema:sdLicense https://scigraph.springernature.com/explorer/license/
88 schema:sdPublisher Nca4bd0481af24dcfa7d384d7015c12df
89 schema:url http://link.springer.com/10.1007/s00702-010-0539-8
90 sgo:license sg:explorer/license/
91 sgo:sdDataset articles
92 rdf:type schema:ScholarlyArticle
93 N07ff9f210da546a3b6c7c5f18c074ac7 rdf:first sg:person.01335531003.77
94 rdf:rest Nbff8cb469c484520b363b3be4f97fc82
95 N0fa6b6db6fac41d29a4971ebc1947b3d rdf:first sg:person.0772561771.46
96 rdf:rest Nefdaceb2a4ab4d12999e3ba7473aa28c
97 N1b3038ae4a0c404486b40f89b9d16dd3 rdf:first sg:person.01237357563.44
98 rdf:rest N46ff9bf6176540f58297ec939de18cfd
99 N24cd29458f484f5491cdce51f5c9520c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Female
101 rdf:type schema:DefinedTerm
102 N2a27ecfe0c1c4eaba0617d51615aff4a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Hippocampus
104 rdf:type schema:DefinedTerm
105 N31cda6a771374f83a04fc1bde1bcaea5 schema:name pubmed_id
106 schema:value 21190051
107 rdf:type schema:PropertyValue
108 N39d8ab7930da4d938122cef320ae81b9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Apolipoproteins E
110 rdf:type schema:DefinedTerm
111 N46ff9bf6176540f58297ec939de18cfd rdf:first sg:person.01105723234.32
112 rdf:rest rdf:nil
113 N4c7b07f16072439f988a4068c8116cd2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Polymerase Chain Reaction
115 rdf:type schema:DefinedTerm
116 N4d89efa58d674793b2ac76c58e1e8b4f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Young Adult
118 rdf:type schema:DefinedTerm
119 N4ea422f2b80f49e29e59fca9fbce476e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Humans
121 rdf:type schema:DefinedTerm
122 N512d8345084f42b99d2e7e4dbe02004d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Brain-Derived Neurotrophic Factor
124 rdf:type schema:DefinedTerm
125 N52f81a67269c4bf5a0e8f1f1cd0d3337 rdf:first sg:person.0757224165.00
126 rdf:rest N0fa6b6db6fac41d29a4971ebc1947b3d
127 N6375b6ad89e94d88b59cc8f2c0876151 rdf:first sg:person.0730513364.28
128 rdf:rest Nad9573b3d37b41939a131d60aa8edf73
129 N65a4b0f445b148c3a03f3390e9a553ee schema:name dimensions_id
130 schema:value pub.1051269234
131 rdf:type schema:PropertyValue
132 N6d8c231a87994097b6e7b28819291058 schema:name nlm_unique_id
133 schema:value 9702341
134 rdf:type schema:PropertyValue
135 N84a185d25e8142539e1f4164d082561f schema:name readcube_id
136 schema:value f439a1730f8132fa4258f8cb53dd65d4dda43d9f9af16fbcf79bbe725087e8a5
137 rdf:type schema:PropertyValue
138 N865007cef29c48ea861a246c2a9782d1 rdf:first sg:person.0757536766.17
139 rdf:rest N1b3038ae4a0c404486b40f89b9d16dd3
140 N8ae8cc920a4242eab0ced2088f9300e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Memory
142 rdf:type schema:DefinedTerm
143 N923432a3409d4bb0a53455d1ea10cf8d rdf:first sg:person.01061442307.05
144 rdf:rest Nea8dde33ad3f4979930c16515d4139c8
145 N93942af4aa0b4b31afa00d6f1299ce13 schema:volumeNumber 118
146 rdf:type schema:PublicationVolume
147 Na6c1743a0d3d4ebeaa166456b02e3a42 schema:name doi
148 schema:value 10.1007/s00702-010-0539-8
149 rdf:type schema:PropertyValue
150 Nad9573b3d37b41939a131d60aa8edf73 rdf:first sg:person.01324776247.58
151 rdf:rest N52f81a67269c4bf5a0e8f1f1cd0d3337
152 Nb6b0814e98f44ec6847679817461786f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Genetic Predisposition to Disease
154 rdf:type schema:DefinedTerm
155 Nbff8cb469c484520b363b3be4f97fc82 rdf:first sg:person.0660240103.66
156 rdf:rest N6375b6ad89e94d88b59cc8f2c0876151
157 Nca4bd0481af24dcfa7d384d7015c12df schema:name Springer Nature - SN SciGraph project
158 rdf:type schema:Organization
159 Ndfbab40f86cc48a9916c264f8aeb35f6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Polymorphism, Single Nucleotide
161 rdf:type schema:DefinedTerm
162 Nea8dde33ad3f4979930c16515d4139c8 rdf:first sg:person.01115350015.49
163 rdf:rest N07ff9f210da546a3b6c7c5f18c074ac7
164 Nefdaceb2a4ab4d12999e3ba7473aa28c rdf:first sg:person.01272020411.15
165 rdf:rest N865007cef29c48ea861a246c2a9782d1
166 Nf8a2404ec06041c5bd2e357d1c32c96f schema:issueNumber 2
167 rdf:type schema:PublicationIssue
168 Nfb2de789c4644b8386415d75fba2f42b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Male
170 rdf:type schema:DefinedTerm
171 anzsrc-for:17 schema:inDefinedTermSet anzsrc-for:
172 schema:name Psychology and Cognitive Sciences
173 rdf:type schema:DefinedTerm
174 anzsrc-for:1701 schema:inDefinedTermSet anzsrc-for:
175 schema:name Psychology
176 rdf:type schema:DefinedTerm
177 sg:journal.1312227 schema:issn 0300-9564
178 1435-1463
179 schema:name Journal of Neural Transmission
180 rdf:type schema:Periodical
181 sg:person.01061442307.05 schema:affiliation https://www.grid.ac/institutes/grid.5330.5
182 schema:familyName Richter-Schmidinger
183 schema:givenName Tanja
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01061442307.05
185 rdf:type schema:Person
186 sg:person.01105723234.32 schema:affiliation https://www.grid.ac/institutes/grid.5330.5
187 schema:familyName Kornhuber
188 schema:givenName Johannes
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105723234.32
190 rdf:type schema:Person
191 sg:person.01115350015.49 schema:affiliation https://www.grid.ac/institutes/grid.15474.33
192 schema:familyName Alexopoulos
193 schema:givenName Panagiotis
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115350015.49
195 rdf:type schema:Person
196 sg:person.01237357563.44 schema:affiliation https://www.grid.ac/institutes/grid.5330.5
197 schema:familyName Doerfler
198 schema:givenName Arnd
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237357563.44
200 rdf:type schema:Person
201 sg:person.01272020411.15 schema:affiliation https://www.grid.ac/institutes/grid.5560.6
202 schema:familyName Kneib
203 schema:givenName Thomas
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272020411.15
205 rdf:type schema:Person
206 sg:person.01324776247.58 schema:affiliation https://www.grid.ac/institutes/grid.5330.5
207 schema:familyName Rhein
208 schema:givenName Cosima
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01324776247.58
210 rdf:type schema:Person
211 sg:person.01335531003.77 schema:affiliation https://www.grid.ac/institutes/grid.5330.5
212 schema:familyName Horn
213 schema:givenName Marco
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335531003.77
215 rdf:type schema:Person
216 sg:person.0660240103.66 schema:affiliation https://www.grid.ac/institutes/grid.5330.5
217 schema:familyName Maus
218 schema:givenName Sebastian
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660240103.66
220 rdf:type schema:Person
221 sg:person.0730513364.28 schema:affiliation https://www.grid.ac/institutes/grid.5330.5
222 schema:familyName Reichel
223 schema:givenName Martin
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730513364.28
225 rdf:type schema:Person
226 sg:person.0757224165.00 schema:affiliation https://www.grid.ac/institutes/grid.5330.5
227 schema:familyName Lewczuk
228 schema:givenName Piotr
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757224165.00
230 rdf:type schema:Person
231 sg:person.0757536766.17 schema:affiliation https://www.grid.ac/institutes/grid.6936.a
232 schema:familyName Perneczky
233 schema:givenName Robert
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757536766.17
235 rdf:type schema:Person
236 sg:person.0772561771.46 schema:affiliation https://www.grid.ac/institutes/grid.413103.4
237 schema:familyName Sidiropoulos
238 schema:givenName Christos
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772561771.46
240 rdf:type schema:Person
241 sg:pub.10.1007/bf00223534 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050315234
242 https://doi.org/10.1007/bf00223534
243 rdf:type schema:CreativeWork
244 sg:pub.10.1007/s12031-009-9205-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017027097
245 https://doi.org/10.1007/s12031-009-9205-8
246 rdf:type schema:CreativeWork
247 sg:pub.10.1038/35049004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050450113
248 https://doi.org/10.1038/35049004
249 rdf:type schema:CreativeWork
250 sg:pub.10.1038/mp.2008.32 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000526104
251 https://doi.org/10.1038/mp.2008.32
252 rdf:type schema:CreativeWork
253 sg:pub.10.1038/npp.2009.214 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005944548
254 https://doi.org/10.1038/npp.2009.214
255 rdf:type schema:CreativeWork
256 sg:pub.10.1038/sj.mp.4001656 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006268120
257 https://doi.org/10.1038/sj.mp.4001656
258 rdf:type schema:CreativeWork
259 sg:pub.10.1203/pdr.0b013e3181cb8e68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029390202
260 https://doi.org/10.1203/pdr.0b013e3181cb8e68
261 rdf:type schema:CreativeWork
262 https://app.dimensions.ai/details/publication/pub.1078691240 schema:CreativeWork
263 https://app.dimensions.ai/details/publication/pub.1082015936 schema:CreativeWork
264 https://app.dimensions.ai/details/publication/pub.1082015938 schema:CreativeWork
265 https://doi.org/10.1001/archneur.1994.00540210046012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012369119
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1001/archpsyc.63.7.731 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008183898
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1002/1098-1063(2000)10:6<752::aid-hipo1012>3.0.co;2-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1004354224
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1002/ajmg.b.30150 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009418817
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1002/ana.410380122 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037096655
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1002/hipo.20294 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026127527
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1016/j.biopsych.2005.09.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015808175
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1016/j.modgep.2006.03.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035012184
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1016/j.neulet.2004.06.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047494062
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1016/j.neulet.2005.11.067 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000684572
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1016/j.neurobiolaging.2004.01.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003671521
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1016/j.neurobiolaging.2006.12.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029096702
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1016/j.neuroimage.2004.10.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014028205
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1016/j.neuroimage.2009.01.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024447379
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1016/j.neuroimage.2010.01.058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053252226
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1016/s0079-6123(00)28020-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006377329
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1016/s0092-8674(03)00035-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053304729
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1016/s0197-4580(00)00150-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040597555
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1016/s0304-3940(00)01569-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1038885666
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1016/s1474-4422(07)70106-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037182752
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1046/j.1471-4159.1996.67031124.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1009677225
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1055/s-2006-953127 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057468508
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1073/pnas.0500579102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016735939
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1073/pnas.0900345106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006130429
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1080/00207450802325843 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042189772
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1093/cercor/bhl103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015949524
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1096/fj.02-0143fje schema:sameAs https://app.dimensions.ai/details/publication/pub.1003576335
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1111/j.1601-183x.2006.00254.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034853760
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1111/j.1601-183x.2008.00409.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1000275669
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1128/mcb.25.21.9259-9268.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010667349
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1136/jnnp.2004.053645 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048192118
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1136/jnnp.71.3.340 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049286775
328 rdf:type schema:CreativeWork
329 https://doi.org/10.1152/jn.1999.82.6.3196 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074564095
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1176/ajp.2007.164.6.916 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063486903
332 rdf:type schema:CreativeWork
333 https://doi.org/10.1212/01.wnl.0000148478.39691.d3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064346662
334 rdf:type schema:CreativeWork
335 https://doi.org/10.1212/wnl.0b013e3181a2e8d0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064354303
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1523/jneurosci.0046-08.2008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050955809
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1523/jneurosci.13-10-04146.1993 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082642333
340 rdf:type schema:CreativeWork
341 https://doi.org/10.1523/jneurosci.18-17-06830.1998 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083308481
342 rdf:type schema:CreativeWork
343 https://doi.org/10.1523/jneurosci.20-18-07116.2000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074700597
344 rdf:type schema:CreativeWork
345 https://doi.org/10.1523/jneurosci.23-17-06690.2003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075324294
346 rdf:type schema:CreativeWork
347 https://doi.org/10.1523/jneurosci.2680-04.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014563730
348 rdf:type schema:CreativeWork
349 https://doi.org/10.1523/jneurosci.4454-03.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007174324
350 rdf:type schema:CreativeWork
351 https://www.grid.ac/institutes/grid.15474.33 schema:alternateName Rechts der Isar Hospital
352 schema:name Department of Psychiatry and Psychotherapy, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany
353 Department of Psychiatry and Psychotherapy, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany
354 Klinik für Psychiatrie und Psychotherapie, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany
355 rdf:type schema:Organization
356 https://www.grid.ac/institutes/grid.413103.4 schema:alternateName Henry Ford Hospital
357 schema:name Department of Neurology, Henry Ford Hospital, Detroit, USA
358 Department of Psychiatry and Psychotherapy, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany
359 rdf:type schema:Organization
360 https://www.grid.ac/institutes/grid.5330.5 schema:alternateName University of Erlangen-Nuremberg
361 schema:name Department of Neuroradiology, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany
362 Department of Psychiatry and Psychotherapy, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany
363 rdf:type schema:Organization
364 https://www.grid.ac/institutes/grid.5560.6 schema:alternateName Carl von Ossietzky University of Oldenburg
365 schema:name Institute of Mathematics, Carl von Ossietzky Universität Oldenburg, Oldenburg, Germany
366 rdf:type schema:Organization
367 https://www.grid.ac/institutes/grid.6936.a schema:alternateName Technical University Munich
368 schema:name Department of Psychiatry and Psychotherapy, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany
369 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...