Selective perioperative steroid supplementation protocol in patients undergoing endoscopic transsphenoidal surgery for pituitary adenomas View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2020-08-09

AUTHORS

Shireen R. Chacko, Ananth P. Abraham, Hesarghatta Shyamasunder Asha, Nitin Kapoor, Simon Rajaratnam, Ari G. Chacko

ABSTRACT

BackgroundThere is no consensus regarding the use of perioperative steroids for transsphenoidal pituitary surgery. We audited the effectiveness and safety of our selective perioperative steroid supplementation protocol in patients with pituitary adenomas.MethodsTwo hundred ninety-seven patients underwent 306 endoscopic transsphenoidal surgeries for removal of their pituitary tumors. Steroids were given to those with an impaired hypothalamic-pituitary-adrenal (HPA) axis, age ≥ 60 years, clinical apoplexy, hyponatremia, or if the pituitary gland was not preserved at surgery. We excluded 111 patients in whom the integrity of the HPA axis could not be determined. We compared the incidence of early postoperative adrenal insufficiency and complications in 135 patients with intact HPA axes who underwent surgery without steroids (group A) with 60 patients who had compromised preoperative HPA axes and received perioperative steroids (group B). In addition, we audited the total number of protocol violations during this period.ResultsFive patients (3.7%) in group A developed postoperative hypocortisolemia. There was no significant difference in the incidence of cerebrospinal fluid leak, diabetes insipidus, or hyponatremia between both groups. There were protocol deviations in 47 (15.4%) patients. Twenty one of these patients did not receive perioperative steroids in violation of the protocol, of whom 4 (19%) developed postoperative hypocortisolemia.ConclusionsOur steroid sparing protocol was both safe and effective. The 15% incidence of protocol deviations is a reminder that the rigorous usage of checklists is mandatory for successful clinical practice. More... »

PAGES

2381-2388

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00701-020-04530-3

DOI

http://dx.doi.org/10.1007/s00701-020-04530-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1129992543

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/32772164


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adenoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cerebrospinal Fluid Leak", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Endoscopy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hormone Replacement Therapy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydrocortisone", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypothalamo-Hypophyseal System", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neurosurgical Procedures", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Perioperative Care", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pituitary Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pituitary-Adrenal System", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sphenoid Bone", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Steroids", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Neurological Sciences, Christian Medical College, 632004, Vellore, Tamil Nadu, India", 
          "id": "http://www.grid.ac/institutes/grid.11586.3b", 
          "name": [
            "Department of Neurological Sciences, Christian Medical College, 632004, Vellore, Tamil Nadu, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chacko", 
        "givenName": "Shireen R.", 
        "id": "sg:person.014255642073.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014255642073.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Neurological Sciences, Christian Medical College, 632004, Vellore, Tamil Nadu, India", 
          "id": "http://www.grid.ac/institutes/grid.11586.3b", 
          "name": [
            "Department of Neurological Sciences, Christian Medical College, 632004, Vellore, Tamil Nadu, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abraham", 
        "givenName": "Ananth P.", 
        "id": "sg:person.01176466532.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176466532.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Endocrinology, Christian Medical College, Vellore, Tamil Nadu, India", 
          "id": "http://www.grid.ac/institutes/grid.11586.3b", 
          "name": [
            "Department of Endocrinology, Christian Medical College, Vellore, Tamil Nadu, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Asha", 
        "givenName": "Hesarghatta Shyamasunder", 
        "id": "sg:person.01146071351.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146071351.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Endocrinology, Christian Medical College, Vellore, Tamil Nadu, India", 
          "id": "http://www.grid.ac/institutes/grid.11586.3b", 
          "name": [
            "Department of Endocrinology, Christian Medical College, Vellore, Tamil Nadu, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kapoor", 
        "givenName": "Nitin", 
        "id": "sg:person.01052357650.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01052357650.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Endocrinology, Christian Medical College, Vellore, Tamil Nadu, India", 
          "id": "http://www.grid.ac/institutes/grid.11586.3b", 
          "name": [
            "Department of Endocrinology, Christian Medical College, Vellore, Tamil Nadu, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rajaratnam", 
        "givenName": "Simon", 
        "id": "sg:person.01322024044.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322024044.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Neurological Sciences, Christian Medical College, 632004, Vellore, Tamil Nadu, India", 
          "id": "http://www.grid.ac/institutes/grid.11586.3b", 
          "name": [
            "Department of Neurological Sciences, Christian Medical College, 632004, Vellore, Tamil Nadu, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chacko", 
        "givenName": "Ari G.", 
        "id": "sg:person.0710321012.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710321012.31"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s11102-008-0086-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040033635", 
          "https://doi.org/10.1007/s11102-008-0086-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11102-012-0423-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043366740", 
          "https://doi.org/10.1007/s11102-012-0423-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12020-018-1655-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1105255445", 
          "https://doi.org/10.1007/s12020-018-1655-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11060-016-2124-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027512002", 
          "https://doi.org/10.1007/s11060-016-2124-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11102-010-0227-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042170558", 
          "https://doi.org/10.1007/s11102-010-0227-6"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2020-08-09", 
    "datePublishedReg": "2020-08-09", 
    "description": "BackgroundThere is no consensus regarding the use of perioperative steroids for transsphenoidal pituitary surgery. We audited the effectiveness and safety of our selective perioperative steroid supplementation protocol in patients with pituitary adenomas.MethodsTwo hundred ninety-seven patients underwent 306 endoscopic transsphenoidal surgeries for removal of their pituitary tumors. Steroids were given to those with an impaired hypothalamic-pituitary-adrenal (HPA) axis, age\u2009\u2265\u200960\u00a0years, clinical apoplexy, hyponatremia, or if the pituitary gland was not preserved at surgery. We excluded 111 patients in whom the integrity of the HPA axis could not be determined. We compared the incidence of early postoperative adrenal insufficiency and complications in 135 patients with intact HPA axes who underwent surgery without steroids (group A) with 60 patients who had compromised preoperative HPA axes and received perioperative steroids (group B). In addition, we audited the total number of protocol violations during this period.ResultsFive patients (3.7%) in group A developed postoperative hypocortisolemia. There was no significant difference in the incidence of cerebrospinal fluid leak, diabetes insipidus, or hyponatremia between both groups. There were protocol deviations in 47 (15.4%) patients. Twenty one of these patients did not receive perioperative steroids in violation of the protocol, of whom 4 (19%) developed postoperative hypocortisolemia.ConclusionsOur steroid sparing protocol was both safe and effective. The 15% incidence of protocol deviations is a reminder that the rigorous usage of checklists is mandatory for successful clinical practice.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00701-020-04530-3", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1412990", 
        "issn": [
          "0001-6268", 
          "0942-0940"
        ], 
        "name": "Acta Neurochirurgica", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "10", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "162"
      }
    ], 
    "keywords": [
      "endoscopic transsphenoidal surgery", 
      "perioperative steroids", 
      "postoperative hypocortisolemia", 
      "transsphenoidal surgery", 
      "supplementation protocol", 
      "pituitary adenomas", 
      "HPA axes", 
      "protocol deviations", 
      "postoperative adrenal insufficiency", 
      "steroid sparing protocol", 
      "transsphenoidal pituitary surgery", 
      "cerebrospinal fluid leak", 
      "MethodsTwo hundred ninety", 
      "successful clinical practice", 
      "clinical apoplexy", 
      "adrenal insufficiency", 
      "ResultsFive patients", 
      "HPA axis", 
      "adrenal axis", 
      "pituitary surgery", 
      "protocol violations", 
      "pituitary tumors", 
      "group A", 
      "fluid leak", 
      "patients", 
      "surgery", 
      "clinical practice", 
      "pituitary gland", 
      "steroids", 
      "incidence", 
      "hypocortisolemia", 
      "hyponatremia", 
      "significant differences", 
      "adenomas", 
      "total number", 
      "apoplexy", 
      "complications", 
      "insipidus", 
      "BackgroundThere", 
      "tumors", 
      "insufficiency", 
      "protocol", 
      "gland", 
      "age", 
      "leak", 
      "safety", 
      "checklist", 
      "reminders", 
      "group", 
      "years", 
      "axis", 
      "period", 
      "differences", 
      "consensus", 
      "use", 
      "practice", 
      "addition", 
      "nineties", 
      "removal", 
      "integrity", 
      "number", 
      "effectiveness", 
      "deviation", 
      "usage", 
      "rigorous usage", 
      "axes", 
      "violation"
    ], 
    "name": "Selective perioperative steroid supplementation protocol in patients undergoing endoscopic transsphenoidal surgery for pituitary adenomas", 
    "pagination": "2381-2388", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1129992543"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00701-020-04530-3"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "32772164"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00701-020-04530-3", 
      "https://app.dimensions.ai/details/publication/pub.1129992543"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:41", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_849.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00701-020-04530-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00701-020-04530-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00701-020-04530-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00701-020-04530-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00701-020-04530-3'


 

This table displays all metadata directly associated to this object as RDF triples.

261 TRIPLES      21 PREDICATES      116 URIs      103 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00701-020-04530-3 schema:about N2d362afc860043d8a7a27123170aafec
2 N339986876f8a41f58f7c19f5aa9a7cc1
3 N4116556125ac455090a8df1226826eb8
4 N43867ff7fa1247c28a2bfd8a58362cc0
5 N451690b82c8e41eaa235b6b0aa09df77
6 N5a646801a2a548c6ab37f1d31de2432a
7 N669a6c00994641e389cb871e70dd7ae9
8 N6a96933de6004cd2995dbe0b5b3e650f
9 N730ed5804bfc4d0dbdd9f088368e906c
10 N77c6d2c000cc4b44931a20e8731e6123
11 N8505426c4390466cb7e3e0c916e64ab3
12 N90e6549794b244d2b14ce0b7f5302db3
13 N91f9f1a20efb406488daf0595226f5ce
14 Nb39c3c094d924673be993995893e2168
15 Nbdba8691cf254f718cc674aab3672770
16 Nbe67c09609c344679fa98aed575bc467
17 Ne76d237334f742829e8955ebca74551f
18 Nec247a6e6cc641229415e68827f72fc8
19 Nf0f4253d36df493bb3924e055ca14543
20 anzsrc-for:11
21 anzsrc-for:1103
22 schema:author Ne67e0568d71b48b98d1524d39df5cb5b
23 schema:citation sg:pub.10.1007/s11060-016-2124-y
24 sg:pub.10.1007/s11102-008-0086-6
25 sg:pub.10.1007/s11102-010-0227-6
26 sg:pub.10.1007/s11102-012-0423-7
27 sg:pub.10.1007/s12020-018-1655-8
28 schema:datePublished 2020-08-09
29 schema:datePublishedReg 2020-08-09
30 schema:description BackgroundThere is no consensus regarding the use of perioperative steroids for transsphenoidal pituitary surgery. We audited the effectiveness and safety of our selective perioperative steroid supplementation protocol in patients with pituitary adenomas.MethodsTwo hundred ninety-seven patients underwent 306 endoscopic transsphenoidal surgeries for removal of their pituitary tumors. Steroids were given to those with an impaired hypothalamic-pituitary-adrenal (HPA) axis, age ≥ 60 years, clinical apoplexy, hyponatremia, or if the pituitary gland was not preserved at surgery. We excluded 111 patients in whom the integrity of the HPA axis could not be determined. We compared the incidence of early postoperative adrenal insufficiency and complications in 135 patients with intact HPA axes who underwent surgery without steroids (group A) with 60 patients who had compromised preoperative HPA axes and received perioperative steroids (group B). In addition, we audited the total number of protocol violations during this period.ResultsFive patients (3.7%) in group A developed postoperative hypocortisolemia. There was no significant difference in the incidence of cerebrospinal fluid leak, diabetes insipidus, or hyponatremia between both groups. There were protocol deviations in 47 (15.4%) patients. Twenty one of these patients did not receive perioperative steroids in violation of the protocol, of whom 4 (19%) developed postoperative hypocortisolemia.ConclusionsOur steroid sparing protocol was both safe and effective. The 15% incidence of protocol deviations is a reminder that the rigorous usage of checklists is mandatory for successful clinical practice.
31 schema:genre article
32 schema:isAccessibleForFree false
33 schema:isPartOf Nd015d91887c7497d9b7c794d43c72b93
34 Nfbe5d68ca4e64117b25d0f03c2edcb7f
35 sg:journal.1412990
36 schema:keywords BackgroundThere
37 HPA axes
38 HPA axis
39 MethodsTwo hundred ninety
40 ResultsFive patients
41 addition
42 adenomas
43 adrenal axis
44 adrenal insufficiency
45 age
46 apoplexy
47 axes
48 axis
49 cerebrospinal fluid leak
50 checklist
51 clinical apoplexy
52 clinical practice
53 complications
54 consensus
55 deviation
56 differences
57 effectiveness
58 endoscopic transsphenoidal surgery
59 fluid leak
60 gland
61 group
62 group A
63 hypocortisolemia
64 hyponatremia
65 incidence
66 insipidus
67 insufficiency
68 integrity
69 leak
70 nineties
71 number
72 patients
73 period
74 perioperative steroids
75 pituitary adenomas
76 pituitary gland
77 pituitary surgery
78 pituitary tumors
79 postoperative adrenal insufficiency
80 postoperative hypocortisolemia
81 practice
82 protocol
83 protocol deviations
84 protocol violations
85 reminders
86 removal
87 rigorous usage
88 safety
89 significant differences
90 steroid sparing protocol
91 steroids
92 successful clinical practice
93 supplementation protocol
94 surgery
95 total number
96 transsphenoidal pituitary surgery
97 transsphenoidal surgery
98 tumors
99 usage
100 use
101 violation
102 years
103 schema:name Selective perioperative steroid supplementation protocol in patients undergoing endoscopic transsphenoidal surgery for pituitary adenomas
104 schema:pagination 2381-2388
105 schema:productId N0e1657a7562c4a59afcd72a8dcbc0439
106 N688b874f7c624446b5fb0a0d59e6bb26
107 Nd31f9d9ceb6548a5a40e321894324d24
108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1129992543
109 https://doi.org/10.1007/s00701-020-04530-3
110 schema:sdDatePublished 2022-12-01T06:41
111 schema:sdLicense https://scigraph.springernature.com/explorer/license/
112 schema:sdPublisher N9b6936d0f7db4362969d6658671b91ae
113 schema:url https://doi.org/10.1007/s00701-020-04530-3
114 sgo:license sg:explorer/license/
115 sgo:sdDataset articles
116 rdf:type schema:ScholarlyArticle
117 N0e1657a7562c4a59afcd72a8dcbc0439 schema:name pubmed_id
118 schema:value 32772164
119 rdf:type schema:PropertyValue
120 N2d362afc860043d8a7a27123170aafec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Middle Aged
122 rdf:type schema:DefinedTerm
123 N339986876f8a41f58f7c19f5aa9a7cc1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Pituitary-Adrenal System
125 rdf:type schema:DefinedTerm
126 N4116556125ac455090a8df1226826eb8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Retrospective Studies
128 rdf:type schema:DefinedTerm
129 N43867ff7fa1247c28a2bfd8a58362cc0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Male
131 rdf:type schema:DefinedTerm
132 N451690b82c8e41eaa235b6b0aa09df77 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Female
134 rdf:type schema:DefinedTerm
135 N5a646801a2a548c6ab37f1d31de2432a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Hormone Replacement Therapy
137 rdf:type schema:DefinedTerm
138 N669a6c00994641e389cb871e70dd7ae9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Neurosurgical Procedures
140 rdf:type schema:DefinedTerm
141 N688b874f7c624446b5fb0a0d59e6bb26 schema:name dimensions_id
142 schema:value pub.1129992543
143 rdf:type schema:PropertyValue
144 N6a96933de6004cd2995dbe0b5b3e650f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Humans
146 rdf:type schema:DefinedTerm
147 N6c46fb57090542a88eeb3c878981c084 rdf:first sg:person.01322024044.39
148 rdf:rest Nbee354819daf41bf8f3410e66cec2734
149 N730ed5804bfc4d0dbdd9f088368e906c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Adult
151 rdf:type schema:DefinedTerm
152 N77c6d2c000cc4b44931a20e8731e6123 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Steroids
154 rdf:type schema:DefinedTerm
155 N8505426c4390466cb7e3e0c916e64ab3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Pituitary Neoplasms
157 rdf:type schema:DefinedTerm
158 N87bb482f2ecf4db6b96e0dd9948b4964 rdf:first sg:person.01052357650.06
159 rdf:rest N6c46fb57090542a88eeb3c878981c084
160 N90e6549794b244d2b14ce0b7f5302db3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Aged
162 rdf:type schema:DefinedTerm
163 N91f9f1a20efb406488daf0595226f5ce schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Cerebrospinal Fluid Leak
165 rdf:type schema:DefinedTerm
166 N9b6936d0f7db4362969d6658671b91ae schema:name Springer Nature - SN SciGraph project
167 rdf:type schema:Organization
168 Naaa5c717e5ca4a518c481fa3bac75876 rdf:first sg:person.01146071351.24
169 rdf:rest N87bb482f2ecf4db6b96e0dd9948b4964
170 Nacf65e49f5194164afd806f75ed0e880 rdf:first sg:person.01176466532.17
171 rdf:rest Naaa5c717e5ca4a518c481fa3bac75876
172 Nb39c3c094d924673be993995893e2168 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Adenoma
174 rdf:type schema:DefinedTerm
175 Nbdba8691cf254f718cc674aab3672770 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Perioperative Care
177 rdf:type schema:DefinedTerm
178 Nbe67c09609c344679fa98aed575bc467 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Hydrocortisone
180 rdf:type schema:DefinedTerm
181 Nbee354819daf41bf8f3410e66cec2734 rdf:first sg:person.0710321012.31
182 rdf:rest rdf:nil
183 Nd015d91887c7497d9b7c794d43c72b93 schema:volumeNumber 162
184 rdf:type schema:PublicationVolume
185 Nd31f9d9ceb6548a5a40e321894324d24 schema:name doi
186 schema:value 10.1007/s00701-020-04530-3
187 rdf:type schema:PropertyValue
188 Ne67e0568d71b48b98d1524d39df5cb5b rdf:first sg:person.014255642073.40
189 rdf:rest Nacf65e49f5194164afd806f75ed0e880
190 Ne76d237334f742829e8955ebca74551f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
191 schema:name Hypothalamo-Hypophyseal System
192 rdf:type schema:DefinedTerm
193 Nec247a6e6cc641229415e68827f72fc8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
194 schema:name Endoscopy
195 rdf:type schema:DefinedTerm
196 Nf0f4253d36df493bb3924e055ca14543 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
197 schema:name Sphenoid Bone
198 rdf:type schema:DefinedTerm
199 Nfbe5d68ca4e64117b25d0f03c2edcb7f schema:issueNumber 10
200 rdf:type schema:PublicationIssue
201 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
202 schema:name Medical and Health Sciences
203 rdf:type schema:DefinedTerm
204 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
205 schema:name Clinical Sciences
206 rdf:type schema:DefinedTerm
207 sg:journal.1412990 schema:issn 0001-6268
208 0942-0940
209 schema:name Acta Neurochirurgica
210 schema:publisher Springer Nature
211 rdf:type schema:Periodical
212 sg:person.01052357650.06 schema:affiliation grid-institutes:grid.11586.3b
213 schema:familyName Kapoor
214 schema:givenName Nitin
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01052357650.06
216 rdf:type schema:Person
217 sg:person.01146071351.24 schema:affiliation grid-institutes:grid.11586.3b
218 schema:familyName Asha
219 schema:givenName Hesarghatta Shyamasunder
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146071351.24
221 rdf:type schema:Person
222 sg:person.01176466532.17 schema:affiliation grid-institutes:grid.11586.3b
223 schema:familyName Abraham
224 schema:givenName Ananth P.
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176466532.17
226 rdf:type schema:Person
227 sg:person.01322024044.39 schema:affiliation grid-institutes:grid.11586.3b
228 schema:familyName Rajaratnam
229 schema:givenName Simon
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322024044.39
231 rdf:type schema:Person
232 sg:person.014255642073.40 schema:affiliation grid-institutes:grid.11586.3b
233 schema:familyName Chacko
234 schema:givenName Shireen R.
235 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014255642073.40
236 rdf:type schema:Person
237 sg:person.0710321012.31 schema:affiliation grid-institutes:grid.11586.3b
238 schema:familyName Chacko
239 schema:givenName Ari G.
240 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710321012.31
241 rdf:type schema:Person
242 sg:pub.10.1007/s11060-016-2124-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1027512002
243 https://doi.org/10.1007/s11060-016-2124-y
244 rdf:type schema:CreativeWork
245 sg:pub.10.1007/s11102-008-0086-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040033635
246 https://doi.org/10.1007/s11102-008-0086-6
247 rdf:type schema:CreativeWork
248 sg:pub.10.1007/s11102-010-0227-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042170558
249 https://doi.org/10.1007/s11102-010-0227-6
250 rdf:type schema:CreativeWork
251 sg:pub.10.1007/s11102-012-0423-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043366740
252 https://doi.org/10.1007/s11102-012-0423-7
253 rdf:type schema:CreativeWork
254 sg:pub.10.1007/s12020-018-1655-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105255445
255 https://doi.org/10.1007/s12020-018-1655-8
256 rdf:type schema:CreativeWork
257 grid-institutes:grid.11586.3b schema:alternateName Department of Endocrinology, Christian Medical College, Vellore, Tamil Nadu, India
258 Department of Neurological Sciences, Christian Medical College, 632004, Vellore, Tamil Nadu, India
259 schema:name Department of Endocrinology, Christian Medical College, Vellore, Tamil Nadu, India
260 Department of Neurological Sciences, Christian Medical College, 632004, Vellore, Tamil Nadu, India
261 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...