Evaluation of Treatment for Synchronous Hepatic Metastases from Gastric Cancer with Special Reference to Long-Term Survivors View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-07

AUTHORS

Katsuyuki Kunieda, Shigetoyo Saji, Yasuyuki Sugiyama, Shinji Osada, Jun Sano, Narutoshi Nagao, Takao Takahashi, Yukihiro Takagi, Yasuaki Arai

ABSTRACT

PURPOSE: The purpose of this study was to determine the most effective means of treating liver metastases from gastric cancer. METHODS: We retrospectively examined 43 patients with liver metastases, but without peritoneal dissemination, who had received different forms of treatment. RESULTS: The crude 5-year survival rates of patients who underwent gastrectomy with complete hepatectomy (curative gastrectomy), noncurative gastrectomy, and no gastrectomy were 33.3%, 3.7%, and 0%, respectively. The curative gastrectomy group showed the highest survival rate (not significant). The median survival of patients given hepatic artery infusion (HAI), systemic chemotherapy, and no chemotherapy were 353, 189, and 61 days, respectively. The patients given chemotherapy survived significantly longer than those not given chemotherapy. Three patients survived for more than 5 years without any signs of recurrence. The long-term survivors all had primary lesions without serosal invasion (T2) and no other noncurative factors. Two patients underwent curative gastrectomy and one underwent noncurative gastrectomy. All were given postoperative chemotherapy; as HAI in two cases, and as systemic chemotherapy in one case. CONCLUSION: These findings suggest that curative gastrectomy combined with HAI or systemic chemotherapy should be attempted for patients with primary tumors without serosal invasion or any other noncurative factors. More... »

PAGES

587-593

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s005950200106

DOI

http://dx.doi.org/10.1007/s005950200106

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019116010

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12111514


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