Solitary Schwannoma of the Colon: Report of Two Cases View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-09

AUTHORS

Satoshi Inagawa, Masao Hori, Jiro Shimazaki, Shigemi Matsumoto, Hiroshi Ishii, Masayuki Itabashi, Shinya Adachi, Toru Kawamoto, Katashi Fukao

ABSTRACT

Some patients with gastrointestinal schwannoma (GIS) have been previously reported in the literature. However, GIS of the colon is quite rare. In addition, it is sometimes difficult to differentiate neurogenic tumors from other soft tissue tumors. We herein describe two cases of schwannoma of the colon, while also reviewing the relevant Japanese literature. The first case, a 73-year-old woman underwent a sigmoidectomy with lymph node dissection following the diagnosis of submucosal tumor. In the second case, a submucosal tumor was located in the cecum of a 44-year-old man. An endoscopic tumor resection was performed in the second case. The resected tumors measured 3.6 and 1.0 cm in maximal diameter, respectively. Microscopically, the tumors consisted predominantly of spindle-shaped cells that proliferated in an interlaced fashion. Mitosis was rarely seen in these tumors. Immunohistochemically, the tumor cells were strongly positive for S-100 protein, weakly positive for glial fibrillary acidic protein, and negative for CD34, α-smooth-muscle actin, and cytokeratin (CAM 5.2) in both cases. The tumors in the two cases were both diagnosed to be benign schwannoma of the colon. In general, schwannoma of the gastrointestinal tract is considered to be benign and should therefore be distinguished from other spindle-cell tumors or malignancies. Once diagnosed as schwannoma, extensive surgery should be avoided. Actually, such patients tend to show a good postoperative course with no evidence of recurrence. More... »

PAGES

833-838

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s005950170060

DOI

http://dx.doi.org/10.1007/s005950170060

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1003955188

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11686568


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