Early detection of infectious complications using C-reactive protein and the procalcitonin levels after laparoscopic colorectal resection: a prospective cohort study View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2020-08-12

AUTHORS

Teppei Tatsuoka, Takashi Okuyama, Emiko Takeshita, Haruka Oi, Takuji Noro, Takashi Mitsui, Hideyuki Yoshitomi, Masatoshi Oya

ABSTRACT

PurposeThe predictive values of the C-reactive protein (CRP) and procalcitonin (PCT) levels for postoperative infectious complications were investigated in patients who underwent elective laparoscopic resection of colorectal cancer.MethodsA total of 154 consecutive patients who underwent elective laparoscopic resection for colorectal cancer (CRC) were prospectively studied. The CRP and PCT levels on the first postoperative day (POD1) and the fourth postoperative day (POD4) were measured. Any correlations between the CRP and PCT levels on POD1 and POD4 with the occurrence of infectious complications were examined.ResultsInfectious complications occurred in 18 (11.7%) patients. CRP on POD1 and CRP and PCT on POD4 were significantly higher in patients who developed infectious complications than in those who did not. The areas under the receiver operating characteristic curves of CRP on POD1 and CRP and PCT on POD4 were 0.597, 0.763 and 0.768, respectively. The cut-off values of CRP and PCT levels on POD4 were 14.33 mg/dl and 0,264 ng/ml, respectively. Whereas the positive predictive value of an elevated CRP level was high, the negative predictive value of an elevated PCT was high.ConclusionThe CRP and PCT levels on POD4 are both considered to be useful for the early detection of infectious complications after laparoscopic resection of CRC. More... »

PAGES

397-403

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00595-020-02111-6

DOI

http://dx.doi.org/10.1007/s00595-020-02111-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1130071256

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/32785845


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