Long-term outcomes of patch tracheoplasty using collagenous tissue membranes (biosheets) produced by in-body tissue architecture in a beagle model View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-05-16

AUTHORS

Satoshi Umeda, Yasuhide Nakayama, Takeshi Terazawa, Ryosuke Iwai, Shohei Hiwatashi, Kengo Nakahata, Yuichi Takama, Hiroomi Okuyama

ABSTRACT

PurposeAlthough various artificial tracheas have been developed, none have proven satisfactory for clinical use. In-body tissue architecture (IBTA) has enabled us to produce collagenous tissues with a wide range of shapes and sizes to meet the needs of individual recipients. In the present study, we investigated the long-term outcomes of patch tracheoplasty using an IBTA-induced collagenous tissue membrane (“biosheet”) in a beagle model.MethodsNine adult female beagles were used. Biosheets were prepared by embedding cylindrical molds assembled with a silicone rod and a slitting pipe into dorsal subcutaneous pouches for 2 months. The sheets were then implanted by patch tracheoplasty. An endoscopic evaluation was performed after 1, 3, or 12 months. The implanted biosheets were harvested for a histological evaluation at the same time points.ResultsAll animals survived the study. At 1 month after tracheoplasty, the anastomotic parts and internal surface of the biosheets were smooth with ciliated columnar epithelium, which regenerated into the internal surface of the biosheet. The chronological spread of chondrocytes into the biosheet was observed at 3 and 12 months.ConclusionsBiosheets showed excellent performance as a scaffold for trachea regeneration with complete luminal epithelium and partial chondrocytes in a 1-year beagle implantation model of patch tracheoplasty. More... »

PAGES

958-964

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00595-019-01818-5

DOI

http://dx.doi.org/10.1007/s00595-019-01818-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1114500384

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/31098758


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biocompatible Materials", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Models, Animal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dogs", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Membranes, Artificial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reconstructive Surgical Procedures", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tissue Engineering", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Trachea", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tracheal Stenosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Pediatric Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka Suita, 565-0871, Osaka, Japan", 
          "id": "http://www.grid.ac/institutes/grid.136593.b", 
          "name": [
            "Department of Pediatric Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka Suita, 565-0871, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Umeda", 
        "givenName": "Satoshi", 
        "id": "sg:person.014332141321.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014332141321.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Biotube Co., Ltd., 2-13-11, Shinkawa, Chuo, 104-0033, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Biotube Co., Ltd., 2-13-11, Shinkawa, Chuo, 104-0033, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakayama", 
        "givenName": "Yasuhide", 
        "id": "sg:person.01004560530.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01004560530.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Cell Engineering, Graduate School of Chemical Science and Engineering, Hokkaido University, Kita 13 Nishi 8, Kita-ku, 060-8628, Sapporo, Hokkaido, Japan", 
          "id": "http://www.grid.ac/institutes/grid.39158.36", 
          "name": [
            "Division of Cell Engineering, Graduate School of Chemical Science and Engineering, Hokkaido University, Kita 13 Nishi 8, Kita-ku, 060-8628, Sapporo, Hokkaido, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Terazawa", 
        "givenName": "Takeshi", 
        "id": "sg:person.010432561172.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010432561172.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Research Institute of Technology, Okayama University of Science, 1-1 Ridaicho, Kita-ku, 700-0005, Okayama, Japan", 
          "id": "http://www.grid.ac/institutes/grid.444568.f", 
          "name": [
            "Research Institute of Technology, Okayama University of Science, 1-1 Ridaicho, Kita-ku, 700-0005, Okayama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Iwai", 
        "givenName": "Ryosuke", 
        "id": "sg:person.01222700342.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222700342.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pediatric Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka Suita, 565-0871, Osaka, Japan", 
          "id": "http://www.grid.ac/institutes/grid.136593.b", 
          "name": [
            "Department of Pediatric Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka Suita, 565-0871, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hiwatashi", 
        "givenName": "Shohei", 
        "id": "sg:person.012120537404.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012120537404.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pediatric Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka Suita, 565-0871, Osaka, Japan", 
          "id": "http://www.grid.ac/institutes/grid.136593.b", 
          "name": [
            "Department of Pediatric Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka Suita, 565-0871, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakahata", 
        "givenName": "Kengo", 
        "id": "sg:person.01031233017.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031233017.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pediatric Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka Suita, 565-0871, Osaka, Japan", 
          "id": "http://www.grid.ac/institutes/grid.136593.b", 
          "name": [
            "Department of Pediatric Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka Suita, 565-0871, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Takama", 
        "givenName": "Yuichi", 
        "id": "sg:person.01310656735.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01310656735.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pediatric Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka Suita, 565-0871, Osaka, Japan", 
          "id": "http://www.grid.ac/institutes/grid.136593.b", 
          "name": [
            "Department of Pediatric Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka Suita, 565-0871, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Okuyama", 
        "givenName": "Hiroomi", 
        "id": "sg:person.01217410746.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01217410746.09"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/nprot.2014.149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033254991", 
          "https://doi.org/10.1038/nprot.2014.149"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10047-012-0676-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007044114", 
          "https://doi.org/10.1007/s10047-012-0676-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10029-018-1799-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1105679742", 
          "https://doi.org/10.1007/s10029-018-1799-8"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-05-16", 
    "datePublishedReg": "2019-05-16", 
    "description": "PurposeAlthough various artificial tracheas have been developed, none have proven satisfactory for clinical use. In-body tissue architecture (IBTA) has enabled us to produce collagenous tissues with a wide range of shapes and sizes to meet the needs of individual recipients. In the present study, we investigated the long-term outcomes of patch tracheoplasty using an IBTA-induced collagenous tissue membrane (\u201cbiosheet\u201d) in a beagle model.MethodsNine adult female beagles were used. Biosheets were prepared by embedding cylindrical molds assembled with a silicone rod and a slitting pipe into dorsal subcutaneous pouches for 2 months. The sheets were then implanted by patch tracheoplasty. An endoscopic evaluation was performed after 1, 3, or 12\u00a0months. The implanted biosheets were harvested for a histological evaluation at the same time points.ResultsAll animals survived the study. At 1 month after tracheoplasty, the anastomotic parts and internal surface of the biosheets were smooth with ciliated columnar epithelium, which regenerated into the internal surface of the biosheet. The chronological spread of chondrocytes into the biosheet was observed at 3 and 12\u00a0months.ConclusionsBiosheets showed excellent performance as a scaffold for trachea regeneration with complete luminal epithelium and partial chondrocytes in a 1-year beagle implantation model of patch tracheoplasty.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00595-019-01818-5", 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.7522418", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1102161", 
        "issn": [
          "0941-1291", 
          "1436-2813"
        ], 
        "name": "Surgery Today", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "11", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "49"
      }
    ], 
    "keywords": [
      "long-term outcomes", 
      "patch tracheoplasty", 
      "body tissue architecture", 
      "beagle model", 
      "ciliated columnar epithelium", 
      "same time points", 
      "adult female beagles", 
      "tissue membranes", 
      "endoscopic evaluation", 
      "dorsal subcutaneous pouches", 
      "anastomotic part", 
      "ResultsAll animals", 
      "histological evaluation", 
      "luminal epithelium", 
      "tracheoplasty", 
      "female beagles", 
      "columnar epithelium", 
      "tissue architecture", 
      "clinical use", 
      "time points", 
      "months", 
      "silicone rod", 
      "implantation model", 
      "subcutaneous pouches", 
      "artificial trachea", 
      "epithelium", 
      "individual recipients", 
      "present study", 
      "outcomes", 
      "collagenous tissue", 
      "Biosheets", 
      "chondrocytes", 
      "trachea regeneration", 
      "trachea", 
      "iBTA", 
      "recipients", 
      "chronological spread", 
      "beagles", 
      "pouch", 
      "evaluation", 
      "tissue", 
      "study", 
      "animals", 
      "membrane", 
      "spread", 
      "regeneration", 
      "use", 
      "need", 
      "model", 
      "wide range", 
      "part", 
      "internal surface", 
      "size", 
      "scaffolds", 
      "point", 
      "rods", 
      "range", 
      "mold", 
      "surface", 
      "cylindrical mold", 
      "performance", 
      "sheets", 
      "shape", 
      "architecture", 
      "excellent performance", 
      "pipe"
    ], 
    "name": "Long-term outcomes of patch tracheoplasty using collagenous tissue membranes (biosheets) produced by in-body tissue architecture in a beagle model", 
    "pagination": "958-964", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1114500384"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00595-019-01818-5"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "31098758"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00595-019-01818-5", 
      "https://app.dimensions.ai/details/publication/pub.1114500384"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:39", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_813.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00595-019-01818-5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00595-019-01818-5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00595-019-01818-5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00595-019-01818-5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00595-019-01818-5'


 

This table displays all metadata directly associated to this object as RDF triples.

247 TRIPLES      21 PREDICATES      106 URIs      95 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00595-019-01818-5 schema:about N06960e215d8f41cead1206ff1befb069
2 N170a7569832c4e4b9b2b544bdedd072a
3 N3b33e47183954362b6db0e53ab546eb0
4 N4173255cc8524fd89b901c0a47248d41
5 N4f4a3e1e9a464fdd9c73f7c22863c3f8
6 N5a16f6c5299e43259344bfd954dc4e08
7 N76965c9b560f4d65911ae5022752f772
8 Na1e2c23bcca342aa8f9524c1d1e3bcb9
9 Nd2625c6a2b5843cf9463072d18761d58
10 Ne8116031727a4488bd446014ac2a2c8e
11 Nfe63a3190b6b45ad89dabf6f9d887f9b
12 Nfee799c365d44e20b2bbb4e3f2fa14df
13 anzsrc-for:11
14 anzsrc-for:1103
15 schema:author N1f9db9d3ba854f2292f97f817e94e35e
16 schema:citation sg:pub.10.1007/s10029-018-1799-8
17 sg:pub.10.1007/s10047-012-0676-y
18 sg:pub.10.1038/nprot.2014.149
19 schema:datePublished 2019-05-16
20 schema:datePublishedReg 2019-05-16
21 schema:description PurposeAlthough various artificial tracheas have been developed, none have proven satisfactory for clinical use. In-body tissue architecture (IBTA) has enabled us to produce collagenous tissues with a wide range of shapes and sizes to meet the needs of individual recipients. In the present study, we investigated the long-term outcomes of patch tracheoplasty using an IBTA-induced collagenous tissue membrane (“biosheet”) in a beagle model.MethodsNine adult female beagles were used. Biosheets were prepared by embedding cylindrical molds assembled with a silicone rod and a slitting pipe into dorsal subcutaneous pouches for 2 months. The sheets were then implanted by patch tracheoplasty. An endoscopic evaluation was performed after 1, 3, or 12 months. The implanted biosheets were harvested for a histological evaluation at the same time points.ResultsAll animals survived the study. At 1 month after tracheoplasty, the anastomotic parts and internal surface of the biosheets were smooth with ciliated columnar epithelium, which regenerated into the internal surface of the biosheet. The chronological spread of chondrocytes into the biosheet was observed at 3 and 12 months.ConclusionsBiosheets showed excellent performance as a scaffold for trachea regeneration with complete luminal epithelium and partial chondrocytes in a 1-year beagle implantation model of patch tracheoplasty.
22 schema:genre article
23 schema:isAccessibleForFree false
24 schema:isPartOf N5a6b620636854bd69a7e805d9c18e38e
25 Nd0ad6553e71d491990a54c45bfda2e6b
26 sg:journal.1102161
27 schema:keywords Biosheets
28 ResultsAll animals
29 adult female beagles
30 anastomotic part
31 animals
32 architecture
33 artificial trachea
34 beagle model
35 beagles
36 body tissue architecture
37 chondrocytes
38 chronological spread
39 ciliated columnar epithelium
40 clinical use
41 collagenous tissue
42 columnar epithelium
43 cylindrical mold
44 dorsal subcutaneous pouches
45 endoscopic evaluation
46 epithelium
47 evaluation
48 excellent performance
49 female beagles
50 histological evaluation
51 iBTA
52 implantation model
53 individual recipients
54 internal surface
55 long-term outcomes
56 luminal epithelium
57 membrane
58 model
59 mold
60 months
61 need
62 outcomes
63 part
64 patch tracheoplasty
65 performance
66 pipe
67 point
68 pouch
69 present study
70 range
71 recipients
72 regeneration
73 rods
74 same time points
75 scaffolds
76 shape
77 sheets
78 silicone rod
79 size
80 spread
81 study
82 subcutaneous pouches
83 surface
84 time points
85 tissue
86 tissue architecture
87 tissue membranes
88 trachea
89 trachea regeneration
90 tracheoplasty
91 use
92 wide range
93 schema:name Long-term outcomes of patch tracheoplasty using collagenous tissue membranes (biosheets) produced by in-body tissue architecture in a beagle model
94 schema:pagination 958-964
95 schema:productId N167c8483e5de43f78fb6bff77130e06d
96 N663ec5eb549048abb38fe6dccf126f21
97 N714a2f323322479b943667c1f373ddae
98 schema:sameAs https://app.dimensions.ai/details/publication/pub.1114500384
99 https://doi.org/10.1007/s00595-019-01818-5
100 schema:sdDatePublished 2022-12-01T06:39
101 schema:sdLicense https://scigraph.springernature.com/explorer/license/
102 schema:sdPublisher Nbd8d3edd6bc44f7eba29b3aa86c5c8dc
103 schema:url https://doi.org/10.1007/s00595-019-01818-5
104 sgo:license sg:explorer/license/
105 sgo:sdDataset articles
106 rdf:type schema:ScholarlyArticle
107 N06960e215d8f41cead1206ff1befb069 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Time Factors
109 rdf:type schema:DefinedTerm
110 N167c8483e5de43f78fb6bff77130e06d schema:name doi
111 schema:value 10.1007/s00595-019-01818-5
112 rdf:type schema:PropertyValue
113 N170a7569832c4e4b9b2b544bdedd072a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Trachea
115 rdf:type schema:DefinedTerm
116 N1f9db9d3ba854f2292f97f817e94e35e rdf:first sg:person.014332141321.78
117 rdf:rest N94e2eda4d00349758b32bdf9c9eef2bb
118 N213d7d37a242455b9841a35ee8f803f4 rdf:first sg:person.010432561172.29
119 rdf:rest N32ac5316469446e592b6ca6d1261b05e
120 N32ac5316469446e592b6ca6d1261b05e rdf:first sg:person.01222700342.29
121 rdf:rest Nf3d449417f1444beae74e0862be91688
122 N3b33e47183954362b6db0e53ab546eb0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Reconstructive Surgical Procedures
124 rdf:type schema:DefinedTerm
125 N4173255cc8524fd89b901c0a47248d41 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Membranes, Artificial
127 rdf:type schema:DefinedTerm
128 N4f4a3e1e9a464fdd9c73f7c22863c3f8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Treatment Outcome
130 rdf:type schema:DefinedTerm
131 N5a16f6c5299e43259344bfd954dc4e08 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Tracheal Stenosis
133 rdf:type schema:DefinedTerm
134 N5a6b620636854bd69a7e805d9c18e38e schema:volumeNumber 49
135 rdf:type schema:PublicationVolume
136 N663ec5eb549048abb38fe6dccf126f21 schema:name dimensions_id
137 schema:value pub.1114500384
138 rdf:type schema:PropertyValue
139 N714a2f323322479b943667c1f373ddae schema:name pubmed_id
140 schema:value 31098758
141 rdf:type schema:PropertyValue
142 N76965c9b560f4d65911ae5022752f772 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Dogs
144 rdf:type schema:DefinedTerm
145 N94e2eda4d00349758b32bdf9c9eef2bb rdf:first sg:person.01004560530.75
146 rdf:rest N213d7d37a242455b9841a35ee8f803f4
147 Na1e2c23bcca342aa8f9524c1d1e3bcb9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Animals
149 rdf:type schema:DefinedTerm
150 Nab6d1f6c561745f1a8aa711a7774af68 rdf:first sg:person.01217410746.09
151 rdf:rest rdf:nil
152 Nbc51fe450f274a0687352a877335b134 rdf:first sg:person.01310656735.14
153 rdf:rest Nab6d1f6c561745f1a8aa711a7774af68
154 Nbd8d3edd6bc44f7eba29b3aa86c5c8dc schema:name Springer Nature - SN SciGraph project
155 rdf:type schema:Organization
156 Nd0ad6553e71d491990a54c45bfda2e6b schema:issueNumber 11
157 rdf:type schema:PublicationIssue
158 Nd2625c6a2b5843cf9463072d18761d58 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Female
160 rdf:type schema:DefinedTerm
161 Ne8116031727a4488bd446014ac2a2c8e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Tissue Engineering
163 rdf:type schema:DefinedTerm
164 Nf319f85e9f0a483a99529854dd6fc98d rdf:first sg:person.01031233017.52
165 rdf:rest Nbc51fe450f274a0687352a877335b134
166 Nf3d449417f1444beae74e0862be91688 rdf:first sg:person.012120537404.22
167 rdf:rest Nf319f85e9f0a483a99529854dd6fc98d
168 Nfe63a3190b6b45ad89dabf6f9d887f9b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Biocompatible Materials
170 rdf:type schema:DefinedTerm
171 Nfee799c365d44e20b2bbb4e3f2fa14df schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name Disease Models, Animal
173 rdf:type schema:DefinedTerm
174 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
175 schema:name Medical and Health Sciences
176 rdf:type schema:DefinedTerm
177 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
178 schema:name Clinical Sciences
179 rdf:type schema:DefinedTerm
180 sg:grant.7522418 http://pending.schema.org/fundedItem sg:pub.10.1007/s00595-019-01818-5
181 rdf:type schema:MonetaryGrant
182 sg:journal.1102161 schema:issn 0941-1291
183 1436-2813
184 schema:name Surgery Today
185 schema:publisher Springer Nature
186 rdf:type schema:Periodical
187 sg:person.01004560530.75 schema:affiliation grid-institutes:None
188 schema:familyName Nakayama
189 schema:givenName Yasuhide
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01004560530.75
191 rdf:type schema:Person
192 sg:person.01031233017.52 schema:affiliation grid-institutes:grid.136593.b
193 schema:familyName Nakahata
194 schema:givenName Kengo
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031233017.52
196 rdf:type schema:Person
197 sg:person.010432561172.29 schema:affiliation grid-institutes:grid.39158.36
198 schema:familyName Terazawa
199 schema:givenName Takeshi
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010432561172.29
201 rdf:type schema:Person
202 sg:person.012120537404.22 schema:affiliation grid-institutes:grid.136593.b
203 schema:familyName Hiwatashi
204 schema:givenName Shohei
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012120537404.22
206 rdf:type schema:Person
207 sg:person.01217410746.09 schema:affiliation grid-institutes:grid.136593.b
208 schema:familyName Okuyama
209 schema:givenName Hiroomi
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01217410746.09
211 rdf:type schema:Person
212 sg:person.01222700342.29 schema:affiliation grid-institutes:grid.444568.f
213 schema:familyName Iwai
214 schema:givenName Ryosuke
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222700342.29
216 rdf:type schema:Person
217 sg:person.01310656735.14 schema:affiliation grid-institutes:grid.136593.b
218 schema:familyName Takama
219 schema:givenName Yuichi
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01310656735.14
221 rdf:type schema:Person
222 sg:person.014332141321.78 schema:affiliation grid-institutes:grid.136593.b
223 schema:familyName Umeda
224 schema:givenName Satoshi
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014332141321.78
226 rdf:type schema:Person
227 sg:pub.10.1007/s10029-018-1799-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105679742
228 https://doi.org/10.1007/s10029-018-1799-8
229 rdf:type schema:CreativeWork
230 sg:pub.10.1007/s10047-012-0676-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1007044114
231 https://doi.org/10.1007/s10047-012-0676-y
232 rdf:type schema:CreativeWork
233 sg:pub.10.1038/nprot.2014.149 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033254991
234 https://doi.org/10.1038/nprot.2014.149
235 rdf:type schema:CreativeWork
236 grid-institutes:None schema:alternateName Biotube Co., Ltd., 2-13-11, Shinkawa, Chuo, 104-0033, Tokyo, Japan
237 schema:name Biotube Co., Ltd., 2-13-11, Shinkawa, Chuo, 104-0033, Tokyo, Japan
238 rdf:type schema:Organization
239 grid-institutes:grid.136593.b schema:alternateName Department of Pediatric Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka Suita, 565-0871, Osaka, Japan
240 schema:name Department of Pediatric Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka Suita, 565-0871, Osaka, Japan
241 rdf:type schema:Organization
242 grid-institutes:grid.39158.36 schema:alternateName Division of Cell Engineering, Graduate School of Chemical Science and Engineering, Hokkaido University, Kita 13 Nishi 8, Kita-ku, 060-8628, Sapporo, Hokkaido, Japan
243 schema:name Division of Cell Engineering, Graduate School of Chemical Science and Engineering, Hokkaido University, Kita 13 Nishi 8, Kita-ku, 060-8628, Sapporo, Hokkaido, Japan
244 rdf:type schema:Organization
245 grid-institutes:grid.444568.f schema:alternateName Research Institute of Technology, Okayama University of Science, 1-1 Ridaicho, Kita-ku, 700-0005, Okayama, Japan
246 schema:name Research Institute of Technology, Okayama University of Science, 1-1 Ridaicho, Kita-ku, 700-0005, Okayama, Japan
247 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...