Etiology and management of low anterior resection syndrome based on the normal defecation mechanism View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04-01

AUTHORS

Keiji Koda, Masato Yamazaki, Kiyohiko Shuto, Chihiro Kosugi, Mikito Mori, Kazuo Narushima, Isamu Hosokawa, Hiroaki Shimizu

ABSTRACT

Low anterior resection syndrome (LARS) commonly develops after an anal sphincter-preserving operation (SPO). The etiology of LARS is not well understood, as the anatomical components and physiological function of normal defecation, which may be damaged during the SPO, are not well established. SPOs may damage components of the anal canal (such as the internal anal sphincter, longitudinal conjoint muscle, or hiatal ligament), either mechanically or via injury to the nerves that supply these organs. The function of the rectum is substantially impaired by resection of the rectum, division of the rectococcygeus muscle, and/or injury of the nervous supply. When the remnant rectum is small and does not function properly, an important functional role may be played by the neorectum, which is usually constructed from the left side of the colon. Hypermotility of the remnant colon may affect the manifestation of urge fecal incontinence. To develop an SPO that minimizes the risk of LARS, the anatomy and physiology of the structures involved in normal defecation need to be understood better. LARS is managed similarly to fecal incontinence. In particular, management should focus on reducing colonic motility when urge fecal incontinence is the dominant symptom. More... »

PAGES

803-808

References to SciGraph publications

  • 1989-06. The composition of anal basal pressure in INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
  • 2009-05-19. Retrograde colonic irrigation for faecal incontinence after low anterior resection in INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
  • 2016-03-25. Anatomy and Embryology of the Colon, Rectum, and Anus in THE ASCRS TEXTBOOK OF COLON AND RECTAL SURGERY
  • 2013-04-10. Quality of life of patients after low anterior, intersphincteric, and abdominoperineal resection for rectal cancer—a matched-pair analysis in INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
  • 1992-09. The internal anal sphincter can not close the anal canal completely in INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
  • 2007-01-01. Pathophysiology of Faecal Incontinence in FECAL INCONTINENCE
  • 2007-01-01. Anatomy and Physiology of Continence in FECAL INCONTINENCE
  • 2000-11. The Role of the Levator Ani Muscle in Evacuation, Sexual Performance and Pelvic Floor Disorders in INTERNATIONAL UROGYNECOLOGY JOURNAL
  • 2006. Benign Anorectal Diseases, Diagnosis with Endoanal and Endorectal Ultrasound and New Treatment Options in NONE
  • 2016-01-29. Low anterior resection syndrome: a survey of the members of the American Society of Colon and Rectal Surgeons (ASCRS), the Spanish Association of Surgeons (AEC), and the Spanish Society of Coloproctology (AECP) in INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
  • 2013-11-21. Dynamic intersection of the longitudinal muscle and external anal sphincter in the layered structure of the anal canal posterior wall in SURGICAL AND RADIOLOGIC ANATOMY
  • 2007-04-13. A Meta-Analysis of Quality of Life for Abdominoperineal Excision of Rectum versus Anterior Resection for Rectal Cancer in ANNALS OF SURGICAL ONCOLOGY
  • 2014-04-02. Nerves supplying the internal anal sphincter: an immunohistochemical study using donated elderly cadavers in SURGICAL AND RADIOLOGIC ANATOMY
  • 2018-07. Role of transanal irrigation in the treatment of anterior resection syndrome in TECHNIQUES IN COLOPROCTOLOGY
  • 2012-02-26. The Physiology of Human Defecation in DIGESTIVE DISEASES AND SCIENCES
  • 1977-01. Control of the internal anal sphincter (manometric study with human subjects) in PFLÜGERS ARCHIV - EUROPEAN JOURNAL OF PHYSIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00595-019-01795-9

    DOI

    http://dx.doi.org/10.1007/s00595-019-01795-9

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1113175485

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30937634


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Neurosciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Anal Canal", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Colon", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Defecation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Digestive System Surgical Procedures", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Fecal Incontinence", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Gastrointestinal Motility", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Organ Sparing Treatments", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Peripheral Nerve Injuries", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Postoperative Complications", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Reconstructive Surgical Procedures", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Rectum", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Syndrome", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Koda", 
            "givenName": "Keiji", 
            "id": "sg:person.0647155176.80", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647155176.80"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Yamazaki", 
            "givenName": "Masato", 
            "id": "sg:person.0647637172.13", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647637172.13"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Shuto", 
            "givenName": "Kiyohiko", 
            "id": "sg:person.01361326355.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361326355.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kosugi", 
            "givenName": "Chihiro", 
            "id": "sg:person.01213167443.37", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213167443.37"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mori", 
            "givenName": "Mikito", 
            "id": "sg:person.01133656514.23", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133656514.23"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Narushima", 
            "givenName": "Kazuo", 
            "id": "sg:person.01245236012.98", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245236012.98"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hosokawa", 
            "givenName": "Isamu", 
            "id": "sg:person.0700157264.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700157264.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan", 
              "id": "http://www.grid.ac/institutes/grid.412406.5", 
              "name": [
                "Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Shimizu", 
            "givenName": "Hiroaki", 
            "id": "sg:person.01103413111.45", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01103413111.45"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/bf00585532", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014307648", 
              "https://doi.org/10.1007/bf00585532"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01646870", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006680022", 
              "https://doi.org/10.1007/bf01646870"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1245/s10434-007-9402-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039569866", 
              "https://doi.org/10.1245/s10434-007-9402-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10151-018-1829-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1106017415", 
              "https://doi.org/10.1007/s10151-018-1829-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00384-009-0719-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009799228", 
              "https://doi.org/10.1007/s00384-009-0719-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00384-013-1683-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053204778", 
              "https://doi.org/10.1007/s00384-013-1683-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00384-016-2511-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013718492", 
              "https://doi.org/10.1007/s00384-016-2511-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-3-319-25970-3_1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037483336", 
              "https://doi.org/10.1007/978-3-319-25970-3_1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-88-470-0638-6_3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004734857", 
              "https://doi.org/10.1007/978-88-470-0638-6_3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00276-013-1228-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029483597", 
              "https://doi.org/10.1007/s00276-013-1228-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00276-014-1289-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020088168", 
              "https://doi.org/10.1007/s00276-014-1289-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-88-470-0638-6_1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033127713", 
              "https://doi.org/10.1007/978-88-470-0638-6_1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10620-012-2071-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034398407", 
              "https://doi.org/10.1007/s10620-012-2071-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/pl00004028", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005552084", 
              "https://doi.org/10.1007/pl00004028"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/88-470-0507-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053073167", 
              "https://doi.org/10.1007/88-470-0507-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00360358", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018939405", 
              "https://doi.org/10.1007/bf00360358"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2019-04-01", 
        "datePublishedReg": "2019-04-01", 
        "description": "Low anterior resection syndrome (LARS) commonly develops after an anal sphincter-preserving operation (SPO). The etiology of LARS is not well understood, as the anatomical components and physiological function of normal defecation, which may be damaged during the SPO, are not well established. SPOs may damage components of the anal canal (such as the internal anal sphincter, longitudinal conjoint muscle, or hiatal ligament), either mechanically or via injury to the nerves that supply these organs. The function of the rectum is substantially impaired by resection of the rectum, division of the rectococcygeus muscle, and/or injury of the nervous supply. When the remnant rectum is small and does not function properly, an important functional role may be played by the neorectum, which is usually constructed from the left side of the colon. Hypermotility of the remnant colon may affect the manifestation of urge fecal incontinence. To develop an SPO that minimizes the risk of LARS, the anatomy and physiology of the structures involved in normal defecation need to be understood better. LARS is managed similarly to fecal incontinence. In particular, management should focus on reducing colonic motility when urge fecal incontinence is the dominant symptom.", 
        "genre": "article", 
        "id": "sg:pub.10.1007/s00595-019-01795-9", 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1102161", 
            "issn": [
              "0941-1291", 
              "1436-2813"
            ], 
            "name": "Surgery Today", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "10", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "49"
          }
        ], 
        "keywords": [
          "low anterior resection syndrome", 
          "sphincter-preserving operations", 
          "anterior resection syndrome", 
          "urge fecal incontinence", 
          "fecal incontinence", 
          "remnant rectum", 
          "remnant colon", 
          "colonic motility", 
          "anal canal", 
          "dominant symptom", 
          "defecation mechanism", 
          "normal defecation", 
          "rectococcygeus muscle", 
          "nervous supply", 
          "incontinence", 
          "left side", 
          "rectum", 
          "syndrome", 
          "etiology", 
          "injury", 
          "colon", 
          "important functional role", 
          "anatomical components", 
          "physiological functions", 
          "functional role", 
          "neorectum", 
          "resection", 
          "nerve", 
          "hypermotility", 
          "symptoms", 
          "defecation", 
          "muscle", 
          "manifestations", 
          "management", 
          "risk", 
          "organs", 
          "canal", 
          "anatomy", 
          "motility", 
          "physiology", 
          "function", 
          "role", 
          "mechanism", 
          "need", 
          "components", 
          "side", 
          "division", 
          "supply", 
          "operation", 
          "structure"
        ], 
        "name": "Etiology and management of low anterior resection syndrome based on the normal defecation mechanism", 
        "pagination": "803-808", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1113175485"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s00595-019-01795-9"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "30937634"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s00595-019-01795-9", 
          "https://app.dimensions.ai/details/publication/pub.1113175485"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-09-02T16:03", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_807.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1007/s00595-019-01795-9"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00595-019-01795-9'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00595-019-01795-9'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00595-019-01795-9'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00595-019-01795-9'


     

    This table displays all metadata directly associated to this object as RDF triples.

    276 TRIPLES      21 PREDICATES      104 URIs      80 LITERALS      20 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s00595-019-01795-9 schema:about N072431b388fe432d8c7728da944c28d9
    2 N177be0fdc75a4039a1d6e57fab728044
    3 N199ea24c81044898b49c8eb1c807c040
    4 N20c088d92b914074ab8d3ee67950fb93
    5 N2430418d743a469a8049fed2723a11f1
    6 N2753b11a331944a2b9cedfcf0aeb5ca0
    7 N3b2e6f1ce1574363a306456eeccfd389
    8 N5257fdba446f459cb4b6996c31f7ead3
    9 N70b18aac2682450db6760ed6ad105432
    10 N80c8b273db754fb99212613c9f9f4417
    11 N95e27609503545c599878c711950782b
    12 N9a8f47686f9b441aad0bbff238202727
    13 Nfd9a88d7df6147f89b926d828bad296f
    14 anzsrc-for:11
    15 anzsrc-for:1109
    16 schema:author N6ec036909201404abd843c01578a2eac
    17 schema:citation sg:pub.10.1007/88-470-0507-8
    18 sg:pub.10.1007/978-3-319-25970-3_1
    19 sg:pub.10.1007/978-88-470-0638-6_1
    20 sg:pub.10.1007/978-88-470-0638-6_3
    21 sg:pub.10.1007/bf00360358
    22 sg:pub.10.1007/bf00585532
    23 sg:pub.10.1007/bf01646870
    24 sg:pub.10.1007/pl00004028
    25 sg:pub.10.1007/s00276-013-1228-8
    26 sg:pub.10.1007/s00276-014-1289-3
    27 sg:pub.10.1007/s00384-009-0719-x
    28 sg:pub.10.1007/s00384-013-1683-z
    29 sg:pub.10.1007/s00384-016-2511-z
    30 sg:pub.10.1007/s10151-018-1829-7
    31 sg:pub.10.1007/s10620-012-2071-1
    32 sg:pub.10.1245/s10434-007-9402-z
    33 schema:datePublished 2019-04-01
    34 schema:datePublishedReg 2019-04-01
    35 schema:description Low anterior resection syndrome (LARS) commonly develops after an anal sphincter-preserving operation (SPO). The etiology of LARS is not well understood, as the anatomical components and physiological function of normal defecation, which may be damaged during the SPO, are not well established. SPOs may damage components of the anal canal (such as the internal anal sphincter, longitudinal conjoint muscle, or hiatal ligament), either mechanically or via injury to the nerves that supply these organs. The function of the rectum is substantially impaired by resection of the rectum, division of the rectococcygeus muscle, and/or injury of the nervous supply. When the remnant rectum is small and does not function properly, an important functional role may be played by the neorectum, which is usually constructed from the left side of the colon. Hypermotility of the remnant colon may affect the manifestation of urge fecal incontinence. To develop an SPO that minimizes the risk of LARS, the anatomy and physiology of the structures involved in normal defecation need to be understood better. LARS is managed similarly to fecal incontinence. In particular, management should focus on reducing colonic motility when urge fecal incontinence is the dominant symptom.
    36 schema:genre article
    37 schema:isAccessibleForFree false
    38 schema:isPartOf N1f95361d831b455a896f5d12d53e998c
    39 N9baed02c98f74c5d9432268a1302d138
    40 sg:journal.1102161
    41 schema:keywords anal canal
    42 anatomical components
    43 anatomy
    44 anterior resection syndrome
    45 canal
    46 colon
    47 colonic motility
    48 components
    49 defecation
    50 defecation mechanism
    51 division
    52 dominant symptom
    53 etiology
    54 fecal incontinence
    55 function
    56 functional role
    57 hypermotility
    58 important functional role
    59 incontinence
    60 injury
    61 left side
    62 low anterior resection syndrome
    63 management
    64 manifestations
    65 mechanism
    66 motility
    67 muscle
    68 need
    69 neorectum
    70 nerve
    71 nervous supply
    72 normal defecation
    73 operation
    74 organs
    75 physiological functions
    76 physiology
    77 rectococcygeus muscle
    78 rectum
    79 remnant colon
    80 remnant rectum
    81 resection
    82 risk
    83 role
    84 side
    85 sphincter-preserving operations
    86 structure
    87 supply
    88 symptoms
    89 syndrome
    90 urge fecal incontinence
    91 schema:name Etiology and management of low anterior resection syndrome based on the normal defecation mechanism
    92 schema:pagination 803-808
    93 schema:productId N0319d72390fe4e1cb0518cfaebb95736
    94 N485c358260d14152912cd8d1cd0e3a97
    95 N4860bf9c7c7d4be1bb7d82c4238563c0
    96 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113175485
    97 https://doi.org/10.1007/s00595-019-01795-9
    98 schema:sdDatePublished 2022-09-02T16:03
    99 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    100 schema:sdPublisher Nab46c8824feb4d8da16b117f9b7bd795
    101 schema:url https://doi.org/10.1007/s00595-019-01795-9
    102 sgo:license sg:explorer/license/
    103 sgo:sdDataset articles
    104 rdf:type schema:ScholarlyArticle
    105 N02c170d395c04be8a161735665c35fbe rdf:first sg:person.0647637172.13
    106 rdf:rest Ne9f0e8bc2807497293537579e858eefa
    107 N0319d72390fe4e1cb0518cfaebb95736 schema:name dimensions_id
    108 schema:value pub.1113175485
    109 rdf:type schema:PropertyValue
    110 N072431b388fe432d8c7728da944c28d9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    111 schema:name Colon
    112 rdf:type schema:DefinedTerm
    113 N177be0fdc75a4039a1d6e57fab728044 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    114 schema:name Defecation
    115 rdf:type schema:DefinedTerm
    116 N199ea24c81044898b49c8eb1c807c040 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    117 schema:name Humans
    118 rdf:type schema:DefinedTerm
    119 N1f95361d831b455a896f5d12d53e998c schema:issueNumber 10
    120 rdf:type schema:PublicationIssue
    121 N20c088d92b914074ab8d3ee67950fb93 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    122 schema:name Anal Canal
    123 rdf:type schema:DefinedTerm
    124 N2430418d743a469a8049fed2723a11f1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    125 schema:name Syndrome
    126 rdf:type schema:DefinedTerm
    127 N2753b11a331944a2b9cedfcf0aeb5ca0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    128 schema:name Postoperative Complications
    129 rdf:type schema:DefinedTerm
    130 N3b2e6f1ce1574363a306456eeccfd389 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    131 schema:name Peripheral Nerve Injuries
    132 rdf:type schema:DefinedTerm
    133 N485c358260d14152912cd8d1cd0e3a97 schema:name pubmed_id
    134 schema:value 30937634
    135 rdf:type schema:PropertyValue
    136 N4860bf9c7c7d4be1bb7d82c4238563c0 schema:name doi
    137 schema:value 10.1007/s00595-019-01795-9
    138 rdf:type schema:PropertyValue
    139 N4ccc48cf251b4b0bb05478f8da3a8ca4 rdf:first sg:person.01245236012.98
    140 rdf:rest Nae9b5d1dcf8c4176b1e07cb173b54182
    141 N4e2e23c51af4470494968433ac63a270 rdf:first sg:person.01213167443.37
    142 rdf:rest N6c8393fd243d412cac3d1ca791af1085
    143 N5257fdba446f459cb4b6996c31f7ead3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    144 schema:name Rectum
    145 rdf:type schema:DefinedTerm
    146 N622d8e1bd6d04f58a58d7eaaeb27bbdd rdf:first sg:person.01103413111.45
    147 rdf:rest rdf:nil
    148 N6c8393fd243d412cac3d1ca791af1085 rdf:first sg:person.01133656514.23
    149 rdf:rest N4ccc48cf251b4b0bb05478f8da3a8ca4
    150 N6ec036909201404abd843c01578a2eac rdf:first sg:person.0647155176.80
    151 rdf:rest N02c170d395c04be8a161735665c35fbe
    152 N70b18aac2682450db6760ed6ad105432 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    153 schema:name Organ Sparing Treatments
    154 rdf:type schema:DefinedTerm
    155 N80c8b273db754fb99212613c9f9f4417 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    156 schema:name Digestive System Surgical Procedures
    157 rdf:type schema:DefinedTerm
    158 N95e27609503545c599878c711950782b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    159 schema:name Gastrointestinal Motility
    160 rdf:type schema:DefinedTerm
    161 N9a8f47686f9b441aad0bbff238202727 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    162 schema:name Fecal Incontinence
    163 rdf:type schema:DefinedTerm
    164 N9baed02c98f74c5d9432268a1302d138 schema:volumeNumber 49
    165 rdf:type schema:PublicationVolume
    166 Nab46c8824feb4d8da16b117f9b7bd795 schema:name Springer Nature - SN SciGraph project
    167 rdf:type schema:Organization
    168 Nae9b5d1dcf8c4176b1e07cb173b54182 rdf:first sg:person.0700157264.27
    169 rdf:rest N622d8e1bd6d04f58a58d7eaaeb27bbdd
    170 Ne9f0e8bc2807497293537579e858eefa rdf:first sg:person.01361326355.05
    171 rdf:rest N4e2e23c51af4470494968433ac63a270
    172 Nfd9a88d7df6147f89b926d828bad296f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    173 schema:name Reconstructive Surgical Procedures
    174 rdf:type schema:DefinedTerm
    175 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    176 schema:name Medical and Health Sciences
    177 rdf:type schema:DefinedTerm
    178 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
    179 schema:name Neurosciences
    180 rdf:type schema:DefinedTerm
    181 sg:journal.1102161 schema:issn 0941-1291
    182 1436-2813
    183 schema:name Surgery Today
    184 schema:publisher Springer Nature
    185 rdf:type schema:Periodical
    186 sg:person.01103413111.45 schema:affiliation grid-institutes:grid.412406.5
    187 schema:familyName Shimizu
    188 schema:givenName Hiroaki
    189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01103413111.45
    190 rdf:type schema:Person
    191 sg:person.01133656514.23 schema:affiliation grid-institutes:grid.412406.5
    192 schema:familyName Mori
    193 schema:givenName Mikito
    194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133656514.23
    195 rdf:type schema:Person
    196 sg:person.01213167443.37 schema:affiliation grid-institutes:grid.412406.5
    197 schema:familyName Kosugi
    198 schema:givenName Chihiro
    199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213167443.37
    200 rdf:type schema:Person
    201 sg:person.01245236012.98 schema:affiliation grid-institutes:grid.412406.5
    202 schema:familyName Narushima
    203 schema:givenName Kazuo
    204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245236012.98
    205 rdf:type schema:Person
    206 sg:person.01361326355.05 schema:affiliation grid-institutes:grid.412406.5
    207 schema:familyName Shuto
    208 schema:givenName Kiyohiko
    209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361326355.05
    210 rdf:type schema:Person
    211 sg:person.0647155176.80 schema:affiliation grid-institutes:grid.412406.5
    212 schema:familyName Koda
    213 schema:givenName Keiji
    214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647155176.80
    215 rdf:type schema:Person
    216 sg:person.0647637172.13 schema:affiliation grid-institutes:grid.412406.5
    217 schema:familyName Yamazaki
    218 schema:givenName Masato
    219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647637172.13
    220 rdf:type schema:Person
    221 sg:person.0700157264.27 schema:affiliation grid-institutes:grid.412406.5
    222 schema:familyName Hosokawa
    223 schema:givenName Isamu
    224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700157264.27
    225 rdf:type schema:Person
    226 sg:pub.10.1007/88-470-0507-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053073167
    227 https://doi.org/10.1007/88-470-0507-8
    228 rdf:type schema:CreativeWork
    229 sg:pub.10.1007/978-3-319-25970-3_1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037483336
    230 https://doi.org/10.1007/978-3-319-25970-3_1
    231 rdf:type schema:CreativeWork
    232 sg:pub.10.1007/978-88-470-0638-6_1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033127713
    233 https://doi.org/10.1007/978-88-470-0638-6_1
    234 rdf:type schema:CreativeWork
    235 sg:pub.10.1007/978-88-470-0638-6_3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004734857
    236 https://doi.org/10.1007/978-88-470-0638-6_3
    237 rdf:type schema:CreativeWork
    238 sg:pub.10.1007/bf00360358 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018939405
    239 https://doi.org/10.1007/bf00360358
    240 rdf:type schema:CreativeWork
    241 sg:pub.10.1007/bf00585532 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014307648
    242 https://doi.org/10.1007/bf00585532
    243 rdf:type schema:CreativeWork
    244 sg:pub.10.1007/bf01646870 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006680022
    245 https://doi.org/10.1007/bf01646870
    246 rdf:type schema:CreativeWork
    247 sg:pub.10.1007/pl00004028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005552084
    248 https://doi.org/10.1007/pl00004028
    249 rdf:type schema:CreativeWork
    250 sg:pub.10.1007/s00276-013-1228-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029483597
    251 https://doi.org/10.1007/s00276-013-1228-8
    252 rdf:type schema:CreativeWork
    253 sg:pub.10.1007/s00276-014-1289-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020088168
    254 https://doi.org/10.1007/s00276-014-1289-3
    255 rdf:type schema:CreativeWork
    256 sg:pub.10.1007/s00384-009-0719-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1009799228
    257 https://doi.org/10.1007/s00384-009-0719-x
    258 rdf:type schema:CreativeWork
    259 sg:pub.10.1007/s00384-013-1683-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1053204778
    260 https://doi.org/10.1007/s00384-013-1683-z
    261 rdf:type schema:CreativeWork
    262 sg:pub.10.1007/s00384-016-2511-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1013718492
    263 https://doi.org/10.1007/s00384-016-2511-z
    264 rdf:type schema:CreativeWork
    265 sg:pub.10.1007/s10151-018-1829-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106017415
    266 https://doi.org/10.1007/s10151-018-1829-7
    267 rdf:type schema:CreativeWork
    268 sg:pub.10.1007/s10620-012-2071-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034398407
    269 https://doi.org/10.1007/s10620-012-2071-1
    270 rdf:type schema:CreativeWork
    271 sg:pub.10.1245/s10434-007-9402-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1039569866
    272 https://doi.org/10.1245/s10434-007-9402-z
    273 rdf:type schema:CreativeWork
    274 grid-institutes:grid.412406.5 schema:alternateName Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan
    275 schema:name Department of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan
    276 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...