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    "description": "PurposeThe prevention of postoperative recurrence is a critical issue in surgery for Crohn\u2019s disease. Prospective randomized trials in Western countries have shown that the postoperative use of anti-tumor necrosis factor \u03b1-antibodies was effective in reducing the recurrence rate. We investigated the efficacy of infliximab (IFX) for the prevention of postoperative Crohn\u2019s disease recurrence.MethodsWe performed a prospective randomized multicenter study. Patients who underwent intestinal resection were assigned to groups treated with or without IFX. Immediately after surgery, patients in the IFX group received IFX at 5\u00a0mg/kg at 0, 2, and 6\u00a0weeks, followed by every 8\u00a0weeks for 2\u00a0years. The primary study outcome was the proportion of patients with endoscopic and/or clinical recurrence at 2\u00a0years after surgery.ResultsThirty-eight eligible patients participated in this study: 19 in the IFX group and 19 in the non-IFX group. The disease recurrence rate in the IFX group was 52.6% (10/19), which was significantly lower than that in the non-IFX group (94.7% [18/19]).ConclusionThe postoperative use of IFX is effective in preventing Crohn\u2019s disease recurrence for 2\u00a0years.", 
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