The surgical outcomes of lung cancer combined with interstitial pneumonia: a single-institution report View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-06-06

AUTHORS

Daisuke Taniguchi, Naoya Yamasaki, Takuro Miyazaki, Tomoshi Tsuchiya, Keitaro Matsumoto, Go Hatachi, Tomoyuki Kakugawa, Noriho Sakamoto, Hiroshi Mukae, Takeshi Nagayasu

ABSTRACT

PurposeSeveral studies have reported that an acute exacerbation (AE) of idiopathic interstitial pneumonia (IIP) can occur after lung resection in patients with non-small cell lung cancer (NSCLC); however, the perioperative management strategy is controversial.MethodsThe data of lung cancer patients at Nagasaki University Hospital from June 1994 to October 2013 were retrospectively reviewed.ResultsAmong all 1701 NSCLC patients who underwent lung resection, 59 (3.5%) had IIP. Five patients (8.5%) had an AE of IIP following lung resection, three (60%) of whom died in hospital. Univariate and multivariate analyses were performed to identify possible risk factors for AE. The univariate analyses identified LDH and the volume of blood loss as risk factors. The multivariate analysis identified no factors. The treatment for an AE included steroid pulse therapy and neutrophil elastase inhibitor therapy. Direct hemoperfusion with polymyxin B immobilized the fiber column and immunosuppressant therapy was attempted in some of the patients who did not respond to these treatments.ConclusionPatients with lung cancer and IIP have a higher risk of chest surgery and a poor prognosis. Very careful surgery and perioperative management are needed, because AEs are often difficult to AE predict. More... »

PAGES

1397-1404

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00595-017-1551-5

DOI

http://dx.doi.org/10.1007/s00595-017-1551-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1085886282

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28589262


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