A giant Krukenberg tumor from a perforated gastric cancer that was successfully removed after multidisciplinary therapy: report of a case View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-01

AUTHORS

Masaki Sunagawa, Masatoshi Isogai, Tohru Harada, Yuji Kaneoka, Keitaro Kamei, Atsuyuki Maeda, Yuichi Takayama

ABSTRACT

A 46-year-old female underwent total gastrectomy with a combined resection of the pancreatic tail, spleen, and lateral segment of the liver surgery after conservative medical management for a perforated advanced gastric cancer. The histological findings showed poorly differentiated adenocarcinoma, and the tumor was Stage IIIC. S-1 and "Kampo-Juzen-taiho-to" were administered as postoperative adjuvant chemo-immunotherapy. A Krukenberg tumor was identified 4 years later. The histological findings strongly suggested the presence of peritoneal dissemination, and S-1-based combined chemotherapies using key drugs such as CDDP, CPT-11, and taxane with the biochemical response modifier "Lentinan" was administered. However, the Krukenberg tumor rapidly increased in size after 4 years and she complained of abdominal distension. Therefore, it was removed with neither difficulties nor apparent recurrent disease, which was thought to be due to the S-1-based combined chemotherapy and the immunological agents are likely to have contributed to her long survival and good quality of life. More... »

PAGES

171-174

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00595-012-0339-x

DOI

http://dx.doi.org/10.1007/s00595-012-0339-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1050005282

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22987279


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