The impact of gender on clinical outcomes after sustaining a pelvic fracture View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2021-12-02

AUTHORS

Sara S. Soliman, Amanda G. Gaccione, Jaroslaw W. Bilaniuk, John M. Adams, Louis T. DiFazio, Daniel Hakakian, Karen Kong, Rolando H. Rolandelli, Zoltan H. Nemeth

ABSTRACT

IntroductionIn trauma care, pelvic fractures contribute to morbidity and mortality. Since men and women have different pelvic structures and hormonal milieu, we studied if these gender differences affect clinical outcomes after pelvic fractures.MethodsUsing the 2016 American College of Surgeons Trauma Quality Improvement Program (ACS TQIP) database, we stratified 24,425 patients with pelvic fractures by gender. Male and female patients were analyzed for differences in comorbidities, mechanism of injury, complications, and other clinical parameters.ResultsFemale patients were older (p < 0.001) and had more comorbidities (p < 0.001), such as bleeding disorder, congestive heart failure, chronic obstructive pulmonary disorder, dementia, chronic renal failure, diabetes mellitus, and hypertension. Although female patients were sicker before sustaining pelvic fractures, male patients had higher rates of post-trauma complications (p < 0.001), such as acute kidney injury, deep vein thrombosis, unplanned admission to the intensive care unit (ICU), and unplanned return to the operating room (OR). Multivariate logistic regression further supports this as male gender was independently associated with a 26.1% higher risk of developing at least one complication (p < 0.001), despite having a higher average Injury Severity Score (ISS) (21.91 ± 0.09 versus 20.71 ± 0.11, p < 0.001). Interestingly, male patients also had a longer hospital length of stay than female patients (13.36 ± 0.12 days versus 11.8 2± 0.14 days, p < 0.001).ConclusionEven though female patients were older and had more pre-existing comorbidities, male patients developed more complications and had longer hospital stays.Trial registration number Not a clinical trial. More... »

PAGES

1-7

References to SciGraph publications

  • 2018-10-26. Gender differences in trauma, shock and sepsis in MILITARY MEDICAL RESEARCH
  • 2019-02-13. Is there an association between female gender and outcome in severe trauma? A multi-center analysis in the Netherlands in SCANDINAVIAN JOURNAL OF TRAUMA, RESUSCITATION AND EMERGENCY MEDICINE
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    URI

    http://scigraph.springernature.com/pub.10.1007/s00590-021-03163-1

    DOI

    http://dx.doi.org/10.1007/s00590-021-03163-1

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1143546196

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/34855003


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