The role of percutaneous transarterial embolization in the management of spinal bone tumors: a literature review View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2021-08-20

AUTHORS

Giancarlo Facchini, Anna Parmeggiani, Giuliano Peta, Claudia Martella, Alessandro Gasbarrini, Gisberto Evangelisti, Marco Miceli, Giuseppe Rossi

ABSTRACT

PurposeSpinal bone tumors include a heterogeneous broad of primary or metastatic lesions that may present as incidental findings or manifest with painful symptoms and pathological fractures. Optimal management of spine bone lesions is often difficult and treatment algorithms are usually solidly based on surgery. We aimed to evaluate the contribution of trans-arterial embolization in this field, with particular attention to the procedure efficacy, technical difficulties and complications.MethodsWe present a literature review on the role of trans-arterial embolization in the management of spinal bone tumors, both primary and metastatic, evaluating its contribution as preoperative treatment, palliative procedure and standalone curative strategy.ResultsTrans-arterial embolization provides an important contribution to reducing surgery hemorrhagic risks, offering a better visualization of the operating field, and possibly increasing tumor susceptibility to chemotherapy or radiation therapy. Nonetheless, it plays an important part in pain palliation, with the unquestionable advantage of being easily repeatable in case of necessity. Its curative role as a standalone therapy is still subject of debate, and at the present time, satisfactory results have been recorded only in the treatment of aneurysmal bone cysts.ConclusionPercutaneous trans-arterial embolization has established as a highly useful minimally invasive procedure in the management of spinal bone lesions, particularly as adjuvant preoperative therapy and palliative treatment. More... »

PAGES

2839-2851

References to SciGraph publications

  • 2015-11-10. Cervical subtotal en-bloc spondylectomy of C6 mesenchymal chondrosarcoma in EUROPEAN SPINE JOURNAL
  • 2018-06-14. An interdisciplinary consensus on the management of bone metastases from renal cell carcinoma in NATURE REVIEWS UROLOGY
  • 2016-03-11. The role of preoperative vascular embolization in surgery for metastatic spinal tumours in EUROPEAN SPINE JOURNAL
  • 2019-08-09. Outcomes of surgical treatments of spinal metastases: a prospective study in SUPPORTIVE CARE IN CANCER
  • 2001-08. Transcatheter arterial embolization for bone metastases from hepatocellular carcinoma in EUROPEAN RADIOLOGY
  • 2015-12-14. Palliative embolization for metastases of the spine in EUROPEAN JOURNAL OF ORTHOPAEDIC SURGERY & TRAUMATOLOGY
  • 2017-07-20. Multiple myeloma in NATURE REVIEWS DISEASE PRIMERS
  • 2015-06-09. Bone cancer incidence by morphological subtype: a global assessment in CANCER CAUSES & CONTROL
  • 2010-01-14. Giant cell tumour of the sacrum: a suggested algorithm for treatment in EUROPEAN SPINE JOURNAL
  • 2016-12-08. How effective is embolization with N-2-butyl-cyanoacrylate for aneurysmal bone cysts? in INTERNATIONAL ORTHOPAEDICS
  • 2016-07-23. Dynamic contrast-enhanced MRI for the assessment of spinal tumor vascularity: correlation with angiography in EUROPEAN SPINE JOURNAL
  • 2018-09-06. Percutaneous management of bone metastases: state of the art, interventional strategies and joint position statement of the Italian College of MSK Radiology (ICoMSKR) and the Italian College of Interventional Radiology (ICIR) in LA RADIOLOGIA MEDICA
  • 2019-11-14. Concomitant radiotherapy and transarterial chemoembolization reduce skeletal-related events related to bone metastases from renal cell carcinoma in EUROPEAN RADIOLOGY
  • 2010-03. Diffusion-weighted (DW) and dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) for monitoring anticancer therapy in TARGETED ONCOLOGY
  • 2007-01-02. Clinicopathologic Features and Results of Transcatheter Arterial Chemoembolization for Osteosarcoma in CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
  • 2012-03-19. Embolisation of bone metastases from renal cancer in LA RADIOLOGIA MEDICA
  • 2012-08-09. Palliative embolisation for advanced bone sarcomas in LA RADIOLOGIA MEDICA
  • 2013-09-06. Palliative embolization for osteosarcoma in EUROPEAN JOURNAL OF ORTHOPAEDIC SURGERY & TRAUMATOLOGY
  • 2020-04-10. Thoracic aggressive vertebral hemangiomas: multidisciplinary management in a hybrid room in EUROPEAN SPINE JOURNAL
  • 2004-09-16. Preoperative transarterial embolization of vertebral metastases in EUROPEAN SPINE JOURNAL
  • 2017-02-14. Preoperative embolization in patients with metastatic spinal cord compression: mandatory or optional? in WORLD JOURNAL OF SURGICAL ONCOLOGY
  • 2011-03-19. Selective arterial embolisation for bone tumours: experience of 454 cases in LA RADIOLOGIA MEDICA
  • 2009-08-08. Selective arterial embolization of 36 aneurysmal bone cysts of the skeleton with N-2-butyl cyanoacrylate in SKELETAL RADIOLOGY
  • 2018-04-23. Role of interventional radiology in the management of musculoskeletal soft-tissue lesions in LA RADIOLOGIA MEDICA
  • 2021-01-15. Reliability and accuracy of time-resolved contrast-enhanced magnetic resonance angiography in hypervascular spinal metastases prior embolization in EUROPEAN RADIOLOGY
  • 2021-02-07. Percutaneous treatments of primary aneurysmal bone cysts: systematic review and meta-analysis in EUROPEAN JOURNAL OF ORTHOPAEDIC SURGERY & TRAUMATOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00586-021-06963-5

    DOI

    http://dx.doi.org/10.1007/s00586-021-06963-5

    DIMENSIONS

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    PUBMED

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