Risk factors for surgical site infection after posterior fixation surgery and intraoperative radiotherapy for spinal metastases View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-04

AUTHORS

Shurei Sugita, Takahiro Hozumi, Kiyofumi Yamakawa, Takahiro Goto, Taiji Kondo

ABSTRACT

PURPOSE: Posterior surgery with intraoperative radiotherapy for spinal metastases offers effective therapy, as we have reported previously. However, the procedure involves transfer from the operating room to the radiotherapy room, and as these patients are somewhat immunocompromised, the risk of postoperative surgical site infection (SSI) may be increased. The aim of our study was to identify risk factors and patient characteristics associated with postoperative SSI following posterior fixation surgery and intraoperative radiotherapy for spinal metastases. METHODS: Participants comprised 279 patients who underwent IORT for the treatment of spinal metastases between August 2004 and June 2013. Patients who suffered SSI within 1 month after surgery were categorized as infected, and all others were categorized as non-infected. We compared factors of age, sex, use of pre-operative corticosteroid, medical history of diabetes, prognosis scores (Tomita, Tokuhashi, and Katagiri), pre- and postoperative Frankel scale scores, site of tumor origin, administration of pre-operative radiotherapy, operation time, intraoperative blood loss, intraoperative irradiation dose, and pre- and postoperative performance status between groups. RESULTS: SSI occurred in 41 patients (14.7%). Katagiri's and Tokuhashi's prognostic scores (P < 0.05 each), postoperative Frankel scale score (P < 0.01), administration of pre-operative radiotherapy (P < 0.05), and postoperative performance status (P < 0.05) all correlated significantly with occurrence of SSI. Multivariate analysis using those factors revealed administration of pre-operative radiotherapy as a factor independently associated with SSI (P < 0.05). CONCLUSIONS: Patient prognosis, postoperative ambulatory function, and pre-operative radiotherapy were risk factors for SSI in patients with spinal metastases. Duration of surgery and intraoperative blood loss were not associated with occurrence of SSI. More... »

PAGES

1034-1038

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00586-015-4116-6

DOI

http://dx.doi.org/10.1007/s00586-015-4116-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046910124

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26174231


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Multivariate Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Spinal Fusion", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Spinal Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Surgical Wound Infection", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Tokyo Metropolitan Komagome Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415479.a", 
          "name": [
            "Department of Orthopaedic Surgery and Musculoskeletal Oncology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22, Honkomagome, Bunkyo-ku, 113-8677, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sugita", 
        "givenName": "Shurei", 
        "id": "sg:person.01046153154.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046153154.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokyo Metropolitan Komagome Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415479.a", 
          "name": [
            "Department of Orthopaedic Surgery and Musculoskeletal Oncology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22, Honkomagome, Bunkyo-ku, 113-8677, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hozumi", 
        "givenName": "Takahiro", 
        "id": "sg:person.01014371050.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014371050.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokyo Metropolitan Komagome Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415479.a", 
          "name": [
            "Department of Orthopaedic Surgery and Musculoskeletal Oncology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22, Honkomagome, Bunkyo-ku, 113-8677, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yamakawa", 
        "givenName": "Kiyofumi", 
        "id": "sg:person.0746255650.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746255650.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokyo Metropolitan Komagome Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415479.a", 
          "name": [
            "Department of Orthopaedic Surgery and Musculoskeletal Oncology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22, Honkomagome, Bunkyo-ku, 113-8677, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Goto", 
        "givenName": "Takahiro", 
        "id": "sg:person.01176103317.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176103317.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokyo Metropolitan Tama Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.417089.3", 
          "name": [
            "Department of Orthopaedic Surgery, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kondo", 
        "givenName": "Taiji", 
        "id": "sg:person.0771533161.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771533161.27"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1097/00007632-199909150-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005193371"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-199909150-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005193371"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-200208150-00021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007002750"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-200208150-00021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007002750"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-200208150-00021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007002750"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.spinee.2015.01.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008516174"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1302/0301-620x.87b5.15185", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023625179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-200104010-00025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023905257"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-200104010-00025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023905257"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-200104010-00025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023905257"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-199903010-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026249369"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-199903010-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026249369"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00586-013-3127-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027676027", 
          "https://doi.org/10.1007/s00586-013-3127-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-199803150-00015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034066123"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-199803150-00015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034066123"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-199011010-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035065063"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-199011010-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035065063"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00586-005-0979-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035318605", 
          "https://doi.org/10.1007/s00586-005-0979-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00586-005-0979-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035318605", 
          "https://doi.org/10.1007/s00586-005-0979-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00181116", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040128254", 
          "https://doi.org/10.1007/bf00181116"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006534-198003000-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043678256"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006534-198003000-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043678256"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000421-198212000-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045278392"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000421-198212000-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045278392"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/brs.0b013e31819712ca", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047412593"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/brs.0b013e31819712ca", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047412593"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(03)12488-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049412081"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1227/00006123-197912000-00016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049929552"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-200102010-00016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050393220"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007632-200102010-00016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050393220"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0095295", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053713153"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1259/bjr/16265478", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064568105"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.f.01515", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068900401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.f.01515", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068900401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.f.01515", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068900401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.m.00618", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068903530"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.m.00618", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068903530"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.m.00618", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068903530"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3171/spi.2003.98.2.0149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071103604"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3171/spi.2003.98.2.0149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071103604"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3171/spi.2003.98.2.0149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071103604"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082757545", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082757547", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-04", 
    "datePublishedReg": "2016-04-01", 
    "description": "PURPOSE: Posterior surgery with intraoperative radiotherapy for spinal metastases offers effective therapy, as we have reported previously. However, the procedure involves transfer from the operating room to the radiotherapy room, and as these patients are somewhat immunocompromised, the risk of postoperative surgical site infection (SSI) may be increased. The aim of our study was to identify risk factors and patient characteristics associated with postoperative SSI following posterior fixation surgery and intraoperative radiotherapy for spinal metastases.\nMETHODS: Participants comprised 279 patients who underwent IORT for the treatment of spinal metastases between August 2004 and June 2013. Patients who suffered SSI within 1 month after surgery were categorized as infected, and all others were categorized as non-infected. We compared factors of age, sex, use of pre-operative corticosteroid, medical history of diabetes, prognosis scores (Tomita, Tokuhashi, and Katagiri), pre- and postoperative Frankel scale scores, site of tumor origin, administration of pre-operative radiotherapy, operation time, intraoperative blood loss, intraoperative irradiation dose, and pre- and postoperative performance status between groups.\nRESULTS: SSI occurred in 41 patients (14.7%). Katagiri's and Tokuhashi's prognostic scores (P < 0.05 each), postoperative Frankel scale score (P < 0.01), administration of pre-operative radiotherapy (P < 0.05), and postoperative performance status (P < 0.05) all correlated significantly with occurrence of SSI. Multivariate analysis using those factors revealed administration of pre-operative radiotherapy as a factor independently associated with SSI (P < 0.05).\nCONCLUSIONS: Patient prognosis, postoperative ambulatory function, and pre-operative radiotherapy were risk factors for SSI in patients with spinal metastases. Duration of surgery and intraoperative blood loss were not associated with occurrence of SSI.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00586-015-4116-6", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.5897259", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1103376", 
        "issn": [
          "0940-6719", 
          "1432-0932"
        ], 
        "name": "European Spine Journal", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "25"
      }
    ], 
    "name": "Risk factors for surgical site infection after posterior fixation surgery and intraoperative radiotherapy for spinal metastases", 
    "pagination": "1034-1038", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "df7661c3099b6bbb6dc39e6a3e9cca1e93069201af1f3713586181457b2efeeb"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "26174231"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9301980"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00586-015-4116-6"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1046910124"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00586-015-4116-6", 
      "https://app.dimensions.ai/details/publication/pub.1046910124"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T02:02", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8700_00000515.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00586-015-4116-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00586-015-4116-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00586-015-4116-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00586-015-4116-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00586-015-4116-6'


 

This table displays all metadata directly associated to this object as RDF triples.

227 TRIPLES      21 PREDICATES      66 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00586-015-4116-6 schema:about N02ebea4692da491dbd489eb584cbc65d
2 N08ac7f3c9f414fe7a0b5c05e39a3b8e0
3 N1b0c2fb0a5534513918b9b8fad3a6c52
4 N29f297976806473a8bc49a454d8657e2
5 N2f8cd6170a2042d7b6e60d403ad9f953
6 N38de86681aa547f1933908de5e61dbef
7 N7a396c81f39247dab0eb615a2303a7f1
8 N90400fc08ced4a169c730de4b01d5828
9 N9be58fbf6dc54fe8bfe483661aa75f00
10 Na014fec727214328b47e744429970014
11 Na46a140ca71d4a708b4b0af2d865c93b
12 Ne9111691b5e2443abf13607e7fbcf333
13 Nee21cd9d75434cef80a610ded90533b8
14 anzsrc-for:11
15 anzsrc-for:1103
16 schema:author N9a36d698f58b45e5820401419545a123
17 schema:citation sg:pub.10.1007/bf00181116
18 sg:pub.10.1007/s00586-005-0979-2
19 sg:pub.10.1007/s00586-013-3127-4
20 https://app.dimensions.ai/details/publication/pub.1082757545
21 https://app.dimensions.ai/details/publication/pub.1082757547
22 https://doi.org/10.1016/j.spinee.2015.01.005
23 https://doi.org/10.1016/s0140-6736(03)12488-9
24 https://doi.org/10.1097/00000421-198212000-00014
25 https://doi.org/10.1097/00006534-198003000-00010
26 https://doi.org/10.1097/00007632-199011010-00005
27 https://doi.org/10.1097/00007632-199803150-00015
28 https://doi.org/10.1097/00007632-199903010-00014
29 https://doi.org/10.1097/00007632-199909150-00014
30 https://doi.org/10.1097/00007632-200102010-00016
31 https://doi.org/10.1097/00007632-200104010-00025
32 https://doi.org/10.1097/00007632-200208150-00021
33 https://doi.org/10.1097/brs.0b013e31819712ca
34 https://doi.org/10.1227/00006123-197912000-00016
35 https://doi.org/10.1259/bjr/16265478
36 https://doi.org/10.1302/0301-620x.87b5.15185
37 https://doi.org/10.1371/journal.pone.0095295
38 https://doi.org/10.2106/jbjs.f.01515
39 https://doi.org/10.2106/jbjs.m.00618
40 https://doi.org/10.3171/spi.2003.98.2.0149
41 schema:datePublished 2016-04
42 schema:datePublishedReg 2016-04-01
43 schema:description PURPOSE: Posterior surgery with intraoperative radiotherapy for spinal metastases offers effective therapy, as we have reported previously. However, the procedure involves transfer from the operating room to the radiotherapy room, and as these patients are somewhat immunocompromised, the risk of postoperative surgical site infection (SSI) may be increased. The aim of our study was to identify risk factors and patient characteristics associated with postoperative SSI following posterior fixation surgery and intraoperative radiotherapy for spinal metastases. METHODS: Participants comprised 279 patients who underwent IORT for the treatment of spinal metastases between August 2004 and June 2013. Patients who suffered SSI within 1 month after surgery were categorized as infected, and all others were categorized as non-infected. We compared factors of age, sex, use of pre-operative corticosteroid, medical history of diabetes, prognosis scores (Tomita, Tokuhashi, and Katagiri), pre- and postoperative Frankel scale scores, site of tumor origin, administration of pre-operative radiotherapy, operation time, intraoperative blood loss, intraoperative irradiation dose, and pre- and postoperative performance status between groups. RESULTS: SSI occurred in 41 patients (14.7%). Katagiri's and Tokuhashi's prognostic scores (P < 0.05 each), postoperative Frankel scale score (P < 0.01), administration of pre-operative radiotherapy (P < 0.05), and postoperative performance status (P < 0.05) all correlated significantly with occurrence of SSI. Multivariate analysis using those factors revealed administration of pre-operative radiotherapy as a factor independently associated with SSI (P < 0.05). CONCLUSIONS: Patient prognosis, postoperative ambulatory function, and pre-operative radiotherapy were risk factors for SSI in patients with spinal metastases. Duration of surgery and intraoperative blood loss were not associated with occurrence of SSI.
44 schema:genre research_article
45 schema:inLanguage en
46 schema:isAccessibleForFree false
47 schema:isPartOf N0ee4ccb226534b31b3f9749a4b081f5a
48 N5537c92971294705ba9672bf0d4ae30b
49 sg:journal.1103376
50 schema:name Risk factors for surgical site infection after posterior fixation surgery and intraoperative radiotherapy for spinal metastases
51 schema:pagination 1034-1038
52 schema:productId N19204bb735c14c17955bb5471d4d9961
53 N62f55895ef204241b187dc9c22f29baf
54 Nd41fe27c4f3d48fa8b323528113c2525
55 Ne61248d52d104b0cb78a2f3c6fd76b8a
56 Nf86ba9e5ef2847a4ae7053c5414fbef4
57 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046910124
58 https://doi.org/10.1007/s00586-015-4116-6
59 schema:sdDatePublished 2019-04-11T02:02
60 schema:sdLicense https://scigraph.springernature.com/explorer/license/
61 schema:sdPublisher N076daeaf298c45d1b6ee81b5342161ad
62 schema:url http://link.springer.com/10.1007%2Fs00586-015-4116-6
63 sgo:license sg:explorer/license/
64 sgo:sdDataset articles
65 rdf:type schema:ScholarlyArticle
66 N02ebea4692da491dbd489eb584cbc65d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
67 schema:name Risk Factors
68 rdf:type schema:DefinedTerm
69 N076daeaf298c45d1b6ee81b5342161ad schema:name Springer Nature - SN SciGraph project
70 rdf:type schema:Organization
71 N08ac7f3c9f414fe7a0b5c05e39a3b8e0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
72 schema:name Multivariate Analysis
73 rdf:type schema:DefinedTerm
74 N0ee4ccb226534b31b3f9749a4b081f5a schema:issueNumber 4
75 rdf:type schema:PublicationIssue
76 N19204bb735c14c17955bb5471d4d9961 schema:name dimensions_id
77 schema:value pub.1046910124
78 rdf:type schema:PropertyValue
79 N1b0c2fb0a5534513918b9b8fad3a6c52 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Middle Aged
81 rdf:type schema:DefinedTerm
82 N29f297976806473a8bc49a454d8657e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Prognosis
84 rdf:type schema:DefinedTerm
85 N2f8cd6170a2042d7b6e60d403ad9f953 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Retrospective Studies
87 rdf:type schema:DefinedTerm
88 N38de86681aa547f1933908de5e61dbef schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Adult
90 rdf:type schema:DefinedTerm
91 N5537c92971294705ba9672bf0d4ae30b schema:volumeNumber 25
92 rdf:type schema:PublicationVolume
93 N62f55895ef204241b187dc9c22f29baf schema:name pubmed_id
94 schema:value 26174231
95 rdf:type schema:PropertyValue
96 N7a396c81f39247dab0eb615a2303a7f1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Surgical Wound Infection
98 rdf:type schema:DefinedTerm
99 N7d449ce9476048c996789900a62a8cca rdf:first sg:person.01176103317.74
100 rdf:rest Nfd4640321d3f45ad95b0b80ad6b449d3
101 N90400fc08ced4a169c730de4b01d5828 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Spinal Fusion
103 rdf:type schema:DefinedTerm
104 N9a36d698f58b45e5820401419545a123 rdf:first sg:person.01046153154.16
105 rdf:rest Nc7c4c195a7bf40e4922eacd6b58015b8
106 N9be58fbf6dc54fe8bfe483661aa75f00 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Spinal Neoplasms
108 rdf:type schema:DefinedTerm
109 Na014fec727214328b47e744429970014 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Male
111 rdf:type schema:DefinedTerm
112 Na46a140ca71d4a708b4b0af2d865c93b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Aged
114 rdf:type schema:DefinedTerm
115 Nc7c4c195a7bf40e4922eacd6b58015b8 rdf:first sg:person.01014371050.22
116 rdf:rest Nd7f54522353145199f18a96c9061cfe6
117 Nd41fe27c4f3d48fa8b323528113c2525 schema:name doi
118 schema:value 10.1007/s00586-015-4116-6
119 rdf:type schema:PropertyValue
120 Nd7f54522353145199f18a96c9061cfe6 rdf:first sg:person.0746255650.00
121 rdf:rest N7d449ce9476048c996789900a62a8cca
122 Ne61248d52d104b0cb78a2f3c6fd76b8a schema:name readcube_id
123 schema:value df7661c3099b6bbb6dc39e6a3e9cca1e93069201af1f3713586181457b2efeeb
124 rdf:type schema:PropertyValue
125 Ne9111691b5e2443abf13607e7fbcf333 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Female
127 rdf:type schema:DefinedTerm
128 Nee21cd9d75434cef80a610ded90533b8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Humans
130 rdf:type schema:DefinedTerm
131 Nf86ba9e5ef2847a4ae7053c5414fbef4 schema:name nlm_unique_id
132 schema:value 9301980
133 rdf:type schema:PropertyValue
134 Nfd4640321d3f45ad95b0b80ad6b449d3 rdf:first sg:person.0771533161.27
135 rdf:rest rdf:nil
136 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
137 schema:name Medical and Health Sciences
138 rdf:type schema:DefinedTerm
139 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
140 schema:name Clinical Sciences
141 rdf:type schema:DefinedTerm
142 sg:grant.5897259 http://pending.schema.org/fundedItem sg:pub.10.1007/s00586-015-4116-6
143 rdf:type schema:MonetaryGrant
144 sg:journal.1103376 schema:issn 0940-6719
145 1432-0932
146 schema:name European Spine Journal
147 rdf:type schema:Periodical
148 sg:person.01014371050.22 schema:affiliation https://www.grid.ac/institutes/grid.415479.a
149 schema:familyName Hozumi
150 schema:givenName Takahiro
151 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014371050.22
152 rdf:type schema:Person
153 sg:person.01046153154.16 schema:affiliation https://www.grid.ac/institutes/grid.415479.a
154 schema:familyName Sugita
155 schema:givenName Shurei
156 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046153154.16
157 rdf:type schema:Person
158 sg:person.01176103317.74 schema:affiliation https://www.grid.ac/institutes/grid.415479.a
159 schema:familyName Goto
160 schema:givenName Takahiro
161 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176103317.74
162 rdf:type schema:Person
163 sg:person.0746255650.00 schema:affiliation https://www.grid.ac/institutes/grid.415479.a
164 schema:familyName Yamakawa
165 schema:givenName Kiyofumi
166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746255650.00
167 rdf:type schema:Person
168 sg:person.0771533161.27 schema:affiliation https://www.grid.ac/institutes/grid.417089.3
169 schema:familyName Kondo
170 schema:givenName Taiji
171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771533161.27
172 rdf:type schema:Person
173 sg:pub.10.1007/bf00181116 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040128254
174 https://doi.org/10.1007/bf00181116
175 rdf:type schema:CreativeWork
176 sg:pub.10.1007/s00586-005-0979-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035318605
177 https://doi.org/10.1007/s00586-005-0979-2
178 rdf:type schema:CreativeWork
179 sg:pub.10.1007/s00586-013-3127-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027676027
180 https://doi.org/10.1007/s00586-013-3127-4
181 rdf:type schema:CreativeWork
182 https://app.dimensions.ai/details/publication/pub.1082757545 schema:CreativeWork
183 https://app.dimensions.ai/details/publication/pub.1082757547 schema:CreativeWork
184 https://doi.org/10.1016/j.spinee.2015.01.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008516174
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1016/s0140-6736(03)12488-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049412081
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1097/00000421-198212000-00014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045278392
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1097/00006534-198003000-00010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043678256
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1097/00007632-199011010-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035065063
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1097/00007632-199803150-00015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034066123
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1097/00007632-199903010-00014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026249369
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1097/00007632-199909150-00014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005193371
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1097/00007632-200102010-00016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050393220
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1097/00007632-200104010-00025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023905257
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1097/00007632-200208150-00021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007002750
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1097/brs.0b013e31819712ca schema:sameAs https://app.dimensions.ai/details/publication/pub.1047412593
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1227/00006123-197912000-00016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049929552
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1259/bjr/16265478 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064568105
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1302/0301-620x.87b5.15185 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023625179
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1371/journal.pone.0095295 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053713153
215 rdf:type schema:CreativeWork
216 https://doi.org/10.2106/jbjs.f.01515 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068900401
217 rdf:type schema:CreativeWork
218 https://doi.org/10.2106/jbjs.m.00618 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068903530
219 rdf:type schema:CreativeWork
220 https://doi.org/10.3171/spi.2003.98.2.0149 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071103604
221 rdf:type schema:CreativeWork
222 https://www.grid.ac/institutes/grid.415479.a schema:alternateName Tokyo Metropolitan Komagome Hospital
223 schema:name Department of Orthopaedic Surgery and Musculoskeletal Oncology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22, Honkomagome, Bunkyo-ku, 113-8677, Tokyo, Japan
224 rdf:type schema:Organization
225 https://www.grid.ac/institutes/grid.417089.3 schema:alternateName Tokyo Metropolitan Tama Medical Center
226 schema:name Department of Orthopaedic Surgery, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan
227 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...