Malignant peripheral nerve sheath tumors presenting as spinal dumbbell tumors: clinical outcomes and characteristic imaging features View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2015-10

AUTHORS

Yoshihiro Matsumoto, Makoto Endo, Katsumi Harimaya, Mitsumasa Hayashida, Toshio Doi, Yukihide Iwamoto

ABSTRACT

PURPOSE: To investigate the clinical outcomes and imaging features of malignant peripheral nerve sheath tumors (MPNSTs) presenting as spinal dumbbell tumors. METHODS: We retrospectively reviewed the clinical outcomes and imaging features of consecutive cases of spinal dumbbell MPNSTs (n=8) and schwannomas (n=15). RESULTS: A maximal diameter>5 cm was more frequently seen in MPNSTs (88%) than in schwannomas (14%). Irregularly lobulated margins occurred frequently in MPNSTs (75%), but not in schwannomas (21%). Indistinguishable boundaries were observed in 63% of MPNSTs, but only 7% of schwannomas. Osteolytic bone destruction was found exclusively in MPNSTs (50% of MPNSTs vs. 0% of schwannomas). CONCLUSIONS: There is little clinical information relating to spinal dumbbell MPNSTs. We propose that the following imaging features are suggestive of spinal dumbbell MPNSTs: maximal diameter>5 cm, irregularly lobulated shape, boundary indistinguishable from surrounding tissues, and osteolytic bone destruction. More... »

PAGES

2119-2125

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00586-014-3467-8

DOI

http://dx.doi.org/10.1007/s00586-014-3467-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009845984

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25015181


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