Trichostatin A (TSA) levels in response to treatment of rainbow trout with gamma-irradiated trophonts against Ichthyophthirius multifiliis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04

AUTHORS

Saeed Moodi, Sakineh Yeganeh, Marzieh Heidarieh, Omid Safari

ABSTRACT

Ichthyophthirius multifiliis is a large ciliated protozoan parasite that is widely distributed in freshwater fish. Histone deacetylase inhibitors (HDACi), e.g., trichostatin A (TSA), are recognized as new agents for the treatment of a wide range of parasitic diseases. In this study, TSA levels induced by gamma-irradiated trophonts and alginate/calcium phosphate nanoparticles were measured after 30 days following treatment against I. multifiliis in spleen, kidney, and liver tissues of rainbow trout. This sounds like TSA is an anti-parasitic enzyme that can increase in spleen, kidney, and liver tissues following treatment of rainbow trout against I. multifiliis (P < 0.05). Moreover, the results obtained from this study showed that the TSA activity level is tissue-dependent. The highest significance levels for TSA activity were found in spleen tissue of treated and healthy groups compared with the levels of the both liver and kidney tissues (P < 0.05). More... »

PAGES

571-574

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00580-019-02903-4

DOI

http://dx.doi.org/10.1007/s00580-019-02903-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111893342


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142 https://www.grid.ac/institutes/grid.459846.2 schema:alternateName Atomic Energy Organization of Iran
143 schema:name Department of Fisheries, Faculty of Animal Sciences and Fisheries, Sari Agricultural Sciences and Natural Resources University (SANRU), Sari, Iran
144 Nuclear Agriculture Research School, Nuclear Science and Technology Research Institute, Karaj, Iran
145 rdf:type schema:Organization
146 https://www.grid.ac/institutes/grid.462824.e schema:alternateName Sari Agricultural Sciences and Natural Resources University
147 schema:name Department of Fisheries, Faculty of Animal Sciences and Fisheries, Sari Agricultural Sciences and Natural Resources University (SANRU), Sari, Iran
148 rdf:type schema:Organization
 




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