Ontology type: schema:ScholarlyArticle
2019-04
AUTHORSSaeed Moodi, Sakineh Yeganeh, Marzieh Heidarieh, Omid Safari
ABSTRACTIchthyophthirius multifiliis is a large ciliated protozoan parasite that is widely distributed in freshwater fish. Histone deacetylase inhibitors (HDACi), e.g., trichostatin A (TSA), are recognized as new agents for the treatment of a wide range of parasitic diseases. In this study, TSA levels induced by gamma-irradiated trophonts and alginate/calcium phosphate nanoparticles were measured after 30 days following treatment against I. multifiliis in spleen, kidney, and liver tissues of rainbow trout. This sounds like TSA is an anti-parasitic enzyme that can increase in spleen, kidney, and liver tissues following treatment of rainbow trout against I. multifiliis (P < 0.05). Moreover, the results obtained from this study showed that the TSA activity level is tissue-dependent. The highest significance levels for TSA activity were found in spleen tissue of treated and healthy groups compared with the levels of the both liver and kidney tissues (P < 0.05). More... »
PAGES571-574
http://scigraph.springernature.com/pub.10.1007/s00580-019-02903-4
DOIhttp://dx.doi.org/10.1007/s00580-019-02903-4
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