Respiratory system compliance and postoperative ventilator dependence in neonates with left-sided congenital diaphragmatic hernia View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-08

AUTHORS

Muneyuki Takeuchi, Keiko Kinouchi, Kazuo Fukumitsu, Kenji Imura, Seiji Kitamura

ABSTRACT

Purpose. The purpose of this prospective consecutive patient study was to test if perioperative respiratory system compliance of patients undergoing surgical repair of congenital diaphragmatic hernia (CDH) can predict the need for prolonged postoperative mechanical ventilation.Methods. All neonates over 35 weeks of gestation who had surgical repair of left-sided CDH between July 1994 and December 1996 (n = 10) were included in this study. Static respiratory system compliance (Crs) was measured by the passive occlusion method with muscle relaxation before (Cpre) and after (Cpost) surgical repair of left-sided CDH. We examined the relationship between respiratory system compliance and postoperative ventilator-dependent duration.Results. The mean birthweight-corrected Cpost was lower than that of birthweight-corrected Cpre (0.41 ± 0.18 vs 0.54 ± 0.18 ml·cmH2O−1·kg−1, P = 0.04). One neonate died on postoperative day 31 from intraventricular hemorrhage, and the other nine neonates survived. The patient who died was excluded from the rest of our calculations. The ventilator-dependent duration was 16.7 ± 12.3 days. The postopera-tive ventilator-dependent duration was longer when the birthweight-corrected Cpost was smaller, with a significant correlation between these parameters (P = 0.006).Conclusion. Cpost, but not Cpre, may be useful to predict the need for prolonged postoperative mechanical ventilation in neonates with left-sided CDH. More... »

PAGES

139-144

References to SciGraph publications

  • 1992-01. Congenital Diaphragmatic Hernia in the Newborn in IRISH JOURNAL OF MEDICAL SCIENCE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s005400170015

    DOI

    http://dx.doi.org/10.1007/s005400170015

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1011459778

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/14566511


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