Evidence-based clinical practice guidelines for chronic pancreatitis 2021 View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2022-08-22

AUTHORS

Kyoko Shimizu, Tetsuhide Ito, Atsushi Irisawa, Takao Ohtsuka, Hirotaka Ohara, Atsushi Kanno, Mitsuhiro Kida, Junichi Sakagami, Naohiro Sata, Yoshifumi Takeyama, Junko Tahara, Morihisa Hirota, Nao Fujimori, Atsushi Masamune, Satoshi Mochida, Nobuyuki Enomoto, Tooru Shimosegawa, Kazuhiko Koike

ABSTRACT

BackgroundChronic pancreatitis (CP) is defined according to the recently proposed mechanistic definition as a pathological fibro-inflammatory syndrome of the pancreas in individuals with genetic, environmental, and/or other risk factors who develop persistent pathological responses to parenchymal injury or stress.MethodsThe clinical practice guidelines for CP in Japan were revised in 2021 based on the 2019 Japanese clinical diagnostic criteria for CP, which incorporate the concept of a pathogenic fibro-inflammatory syndrome in the pancreas. In this third edition, clinical questions are reclassified into clinical questions, background questions, and future research questions.ResultsBased on analysis of newly accumulated evidence, the strength of evidence and recommendations for each clinical question is described in terms of treatment selection, lifestyle guidance, pain control, treatment of exocrine and endocrine insufficiency, and treatment of complications. A flowchart outlining indications, treatment selection, and policies for cases in which treatment is ineffective is provided. For pain control, pharmacological treatment and the indications and timing for endoscopic and surgical treatment have been updated in the revised edition.ConclusionsThese updated guidelines provide clinicians with useful information to assist in the diagnosis and treatment of CP. More... »

PAGES

709-724

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00535-022-01911-6

    DOI

    http://dx.doi.org/10.1007/s00535-022-01911-6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1150401306

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/35994093


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