Current status of primary malignant melanoma of the esophagus: clinical features, pathology, management and prognosis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-11-03

AUTHORS

Yoshimi Iwanuma, Natsumi Tomita, Takayuki Amano, Fuyumi Isayama, Masahiko Tsurumaru, Takuo Hayashi, Yoshiaki Kajiyama

ABSTRACT

Primary malignant melanoma of the esophagus (PMME) is a rare disease with an extremely poor prognosis. Up to 2011, approximately 300 cases had been reported worldwide. The average age of onset is 60.5 years old, with a prevalence of males (2:1). A typical finding of PMME is a lobular or polyploid, well-circumscribed and pigmented tumor, partly covered with normal mucosa. PMME represents various colors depending on its melanin quantity and commonly coexists with intramural metastases, melanocytosis or melanoma in situ. The tumor is located from the middle to lower thoracic esophagus. The accuracy of diagnosis from biopsy is approximately 80%, because many cases are misdiagnosed as a poorly differentiated carcinoma because of the absence of melanin granules. A definite diagnosis was made by immunohistochemical examination with positive results of S100 protein, HMB45 and neuron-specific enolase. PMME has a highly metastatic potential, and the incidence of distant metastasis at the initial diagnosis is around 40–80%. A metastatic tumor from cutaneous malignant melanoma is another pigmented esophageal tumor to be considered when making the differential diagnosis for PMME. Junctional activity with melanotic cells in the adjacent epithelium and the presence of in situ melanoma and/or a satellite tumor without a previous history of cutaneous melanoma are definitive. Most of the reported patients were treated with radical esophagectomy, which is believed to be an effective approach for localized PMME. Five-year survival rates have been achieved in 37% recently, while adjuvant therapy has not been proven to increase overall survival but plays a palliative role. More... »

PAGES

21-28

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00535-011-0490-y

DOI

http://dx.doi.org/10.1007/s00535-011-0490-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048213396

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22048255


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Age of Onset", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diagnosis, Differential", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Esophageal Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Esophagectomy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Melanins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Melanoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Metastasis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sex Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Rate", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.258269.2", 
          "name": [
            "Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Iwanuma", 
        "givenName": "Yoshimi", 
        "id": "sg:person.01026010244.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01026010244.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.258269.2", 
          "name": [
            "Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tomita", 
        "givenName": "Natsumi", 
        "id": "sg:person.0725561510.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725561510.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.258269.2", 
          "name": [
            "Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Amano", 
        "givenName": "Takayuki", 
        "id": "sg:person.0657446310.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657446310.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.258269.2", 
          "name": [
            "Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Isayama", 
        "givenName": "Fuyumi", 
        "id": "sg:person.01250325465.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250325465.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Center, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.258269.2", 
          "name": [
            "Cancer Center, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tsurumaru", 
        "givenName": "Masahiko", 
        "id": "sg:person.0623006417.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623006417.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Human Pathology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.258269.2", 
          "name": [
            "Department of Human Pathology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hayashi", 
        "givenName": "Takuo", 
        "id": "sg:person.0606062302.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0606062302.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.258269.2", 
          "name": [
            "Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kajiyama", 
        "givenName": "Yoshiaki", 
        "id": "sg:person.01042010110.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01042010110.29"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf01606502", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027113988", 
          "https://doi.org/10.1007/bf01606502"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11605-007-0417-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043541960", 
          "https://doi.org/10.1007/s11605-007-0417-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10388-009-0169-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036942194", 
          "https://doi.org/10.1007/s10388-009-0169-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02190531", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007231419", 
          "https://doi.org/10.1007/bf02190531"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/b:ddas.0000043379.60295.cb", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051410532", 
          "https://doi.org/10.1023/b:ddas.0000043379.60295.cb"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s004280000220", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023343732", 
          "https://doi.org/10.1007/s004280000220"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2011-11-03", 
    "datePublishedReg": "2011-11-03", 
    "description": "Primary malignant melanoma of the esophagus (PMME) is a rare disease with an extremely poor prognosis. Up to 2011, approximately 300 cases had been reported worldwide. The average age of onset is 60.5\u00a0years old, with a prevalence of males (2:1). A typical finding of PMME is a lobular or polyploid, well-circumscribed and pigmented tumor, partly covered with normal mucosa. PMME represents various colors depending on its melanin quantity and commonly coexists with intramural metastases, melanocytosis or melanoma in situ. The tumor is located from the middle to lower thoracic esophagus. The accuracy of diagnosis from biopsy is approximately 80%, because many cases are misdiagnosed as a poorly differentiated carcinoma because of the absence of melanin granules. A definite diagnosis was made by immunohistochemical examination with positive results of S100 protein, HMB45 and neuron-specific enolase. PMME has a highly metastatic potential, and the incidence of distant metastasis at the initial diagnosis is around 40\u201380%. A metastatic tumor from cutaneous malignant melanoma is another pigmented esophageal tumor to be considered when making the differential diagnosis for PMME. Junctional activity with melanotic cells in the adjacent epithelium and the presence of in situ melanoma and/or a satellite tumor without a previous history of cutaneous melanoma are definitive. Most of the reported patients were treated with radical esophagectomy, which is believed to be an effective approach for localized PMME. Five-year survival rates have been achieved in 37% recently, while adjuvant therapy has not been proven to increase overall survival but plays a palliative role.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00535-011-0490-y", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1009747", 
        "issn": [
          "0944-1174", 
          "1435-5922"
        ], 
        "name": "Journal of Gastroenterology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "47"
      }
    ], 
    "keywords": [
      "primary malignant melanoma", 
      "malignant melanoma", 
      "five-year survival rate", 
      "cutaneous malignant melanoma", 
      "neuron-specific enolase", 
      "prevalence of males", 
      "accuracy of diagnosis", 
      "intramural metastasis", 
      "adjuvant therapy", 
      "radical esophagectomy", 
      "overall survival", 
      "thoracic esophagus", 
      "distant metastasis", 
      "palliative role", 
      "initial diagnosis", 
      "satellite tumors", 
      "clinical features", 
      "poor prognosis", 
      "definite diagnosis", 
      "metastatic tumors", 
      "esophageal tumors", 
      "cutaneous melanoma", 
      "differentiated carcinoma", 
      "immunohistochemical examination", 
      "differential diagnosis", 
      "situ melanoma", 
      "normal mucosa", 
      "rare disease", 
      "typical findings", 
      "previous history", 
      "average age", 
      "survival rate", 
      "S100 protein", 
      "junctional activity", 
      "melanoma", 
      "metastatic potential", 
      "tumors", 
      "adjacent epithelium", 
      "esophagus", 
      "diagnosis", 
      "melanotic cells", 
      "prognosis", 
      "metastasis", 
      "positive results", 
      "PMME", 
      "melanin quantity", 
      "melanin granules", 
      "esophagectomy", 
      "patients", 
      "biopsy", 
      "carcinoma", 
      "mucosa", 
      "HMB45", 
      "therapy", 
      "melanocytosis", 
      "prevalence", 
      "incidence", 
      "disease", 
      "pathology", 
      "enolase", 
      "epithelium", 
      "survival", 
      "current status", 
      "age", 
      "cases", 
      "onset", 
      "males", 
      "examination", 
      "status", 
      "cells", 
      "years", 
      "findings", 
      "management", 
      "absence", 
      "activity", 
      "history", 
      "effective approach", 
      "protein", 
      "granules", 
      "role", 
      "rate", 
      "presence", 
      "potential", 
      "features", 
      "results", 
      "situ", 
      "middle", 
      "approach", 
      "quantity", 
      "accuracy", 
      "color", 
      "pigmented esophageal tumor"
    ], 
    "name": "Current status of primary malignant melanoma of the esophagus: clinical features, pathology, management and prognosis", 
    "pagination": "21-28", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1048213396"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00535-011-0490-y"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "22048255"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00535-011-0490-y", 
      "https://app.dimensions.ai/details/publication/pub.1048213396"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:24", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_533.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00535-011-0490-y"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00535-011-0490-y'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00535-011-0490-y'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00535-011-0490-y'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00535-011-0490-y'


 

This table displays all metadata directly associated to this object as RDF triples.

280 TRIPLES      22 PREDICATES      138 URIs      124 LITERALS      21 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00535-011-0490-y schema:about N0c66acb7e42947c68b7ca6167b7fa491
2 N152ab299499945a281663af6a796032f
3 N2fe4a70c94fb4f4a8f9dbc8146c5c405
4 N3bfa81baee2642959fcf30aa18a4aab5
5 N44ff051f36214635991f2460ea47b89f
6 N4af672e127fa41e2bce3ce4acf59d742
7 N4dcbf225ecd74388b2c1c3c42fe5c187
8 N6f06ad18b9e3468d912f6188a0d33658
9 N71d303b485a14a1dae8cacd484aabeda
10 Na51f04aaad5549799aee2f2b0ca04fc3
11 Nb1626180e5844c99b439f40d77095ebe
12 Nd2b1235bf0cb495ba204af8d2c00f81e
13 Ne68a100af84b47fbb180302a66361a75
14 Nf6ad1f2fb540403a911b7518be0b896f
15 anzsrc-for:11
16 anzsrc-for:1112
17 schema:author N65c40f6110d145109f8f5f848dc4d7c5
18 schema:citation sg:pub.10.1007/bf01606502
19 sg:pub.10.1007/bf02190531
20 sg:pub.10.1007/s004280000220
21 sg:pub.10.1007/s10388-009-0169-0
22 sg:pub.10.1007/s11605-007-0417-3
23 sg:pub.10.1023/b:ddas.0000043379.60295.cb
24 schema:datePublished 2011-11-03
25 schema:datePublishedReg 2011-11-03
26 schema:description Primary malignant melanoma of the esophagus (PMME) is a rare disease with an extremely poor prognosis. Up to 2011, approximately 300 cases had been reported worldwide. The average age of onset is 60.5 years old, with a prevalence of males (2:1). A typical finding of PMME is a lobular or polyploid, well-circumscribed and pigmented tumor, partly covered with normal mucosa. PMME represents various colors depending on its melanin quantity and commonly coexists with intramural metastases, melanocytosis or melanoma in situ. The tumor is located from the middle to lower thoracic esophagus. The accuracy of diagnosis from biopsy is approximately 80%, because many cases are misdiagnosed as a poorly differentiated carcinoma because of the absence of melanin granules. A definite diagnosis was made by immunohistochemical examination with positive results of S100 protein, HMB45 and neuron-specific enolase. PMME has a highly metastatic potential, and the incidence of distant metastasis at the initial diagnosis is around 40–80%. A metastatic tumor from cutaneous malignant melanoma is another pigmented esophageal tumor to be considered when making the differential diagnosis for PMME. Junctional activity with melanotic cells in the adjacent epithelium and the presence of in situ melanoma and/or a satellite tumor without a previous history of cutaneous melanoma are definitive. Most of the reported patients were treated with radical esophagectomy, which is believed to be an effective approach for localized PMME. Five-year survival rates have been achieved in 37% recently, while adjuvant therapy has not been proven to increase overall survival but plays a palliative role.
27 schema:genre article
28 schema:inLanguage en
29 schema:isAccessibleForFree false
30 schema:isPartOf N4f11208d269e40cfb23b72c30efe3884
31 N8438d44e90d54ceb8768d83c8264cff6
32 sg:journal.1009747
33 schema:keywords HMB45
34 PMME
35 S100 protein
36 absence
37 accuracy
38 accuracy of diagnosis
39 activity
40 adjacent epithelium
41 adjuvant therapy
42 age
43 approach
44 average age
45 biopsy
46 carcinoma
47 cases
48 cells
49 clinical features
50 color
51 current status
52 cutaneous malignant melanoma
53 cutaneous melanoma
54 definite diagnosis
55 diagnosis
56 differential diagnosis
57 differentiated carcinoma
58 disease
59 distant metastasis
60 effective approach
61 enolase
62 epithelium
63 esophageal tumors
64 esophagectomy
65 esophagus
66 examination
67 features
68 findings
69 five-year survival rate
70 granules
71 history
72 immunohistochemical examination
73 incidence
74 initial diagnosis
75 intramural metastasis
76 junctional activity
77 males
78 malignant melanoma
79 management
80 melanin granules
81 melanin quantity
82 melanocytosis
83 melanoma
84 melanotic cells
85 metastasis
86 metastatic potential
87 metastatic tumors
88 middle
89 mucosa
90 neuron-specific enolase
91 normal mucosa
92 onset
93 overall survival
94 palliative role
95 pathology
96 patients
97 pigmented esophageal tumor
98 poor prognosis
99 positive results
100 potential
101 presence
102 prevalence
103 prevalence of males
104 previous history
105 primary malignant melanoma
106 prognosis
107 protein
108 quantity
109 radical esophagectomy
110 rare disease
111 rate
112 results
113 role
114 satellite tumors
115 situ
116 situ melanoma
117 status
118 survival
119 survival rate
120 therapy
121 thoracic esophagus
122 tumors
123 typical findings
124 years
125 schema:name Current status of primary malignant melanoma of the esophagus: clinical features, pathology, management and prognosis
126 schema:pagination 21-28
127 schema:productId N076306e618f84a08b42c69bdba3c5a2b
128 Nd2b03485c0054058a1a84ab7824a692b
129 Nfdc680fd19ed40e7afbba306b0bb16b4
130 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048213396
131 https://doi.org/10.1007/s00535-011-0490-y
132 schema:sdDatePublished 2022-01-01T18:24
133 schema:sdLicense https://scigraph.springernature.com/explorer/license/
134 schema:sdPublisher N71c3b075154b42ff948d0318602ed9d5
135 schema:url https://doi.org/10.1007/s00535-011-0490-y
136 sgo:license sg:explorer/license/
137 sgo:sdDataset articles
138 rdf:type schema:ScholarlyArticle
139 N076306e618f84a08b42c69bdba3c5a2b schema:name dimensions_id
140 schema:value pub.1048213396
141 rdf:type schema:PropertyValue
142 N0c66acb7e42947c68b7ca6167b7fa491 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Melanins
144 rdf:type schema:DefinedTerm
145 N152ab299499945a281663af6a796032f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Female
147 rdf:type schema:DefinedTerm
148 N1bec5db3e8214274adfa448e240506b1 rdf:first sg:person.0623006417.52
149 rdf:rest N56d5a7b1953642bc81869a8c59c8ebd4
150 N2fe4a70c94fb4f4a8f9dbc8146c5c405 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Neoplasm Metastasis
152 rdf:type schema:DefinedTerm
153 N3bfa81baee2642959fcf30aa18a4aab5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Melanoma
155 rdf:type schema:DefinedTerm
156 N44ff051f36214635991f2460ea47b89f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Esophagectomy
158 rdf:type schema:DefinedTerm
159 N4af672e127fa41e2bce3ce4acf59d742 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Male
161 rdf:type schema:DefinedTerm
162 N4dcbf225ecd74388b2c1c3c42fe5c187 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Middle Aged
164 rdf:type schema:DefinedTerm
165 N4f11208d269e40cfb23b72c30efe3884 schema:volumeNumber 47
166 rdf:type schema:PublicationVolume
167 N56d5a7b1953642bc81869a8c59c8ebd4 rdf:first sg:person.0606062302.32
168 rdf:rest N98ddd38afa474d169f7ced3b22e221d7
169 N65c40f6110d145109f8f5f848dc4d7c5 rdf:first sg:person.01026010244.03
170 rdf:rest Neb70196cf53648a697e7c9e791509b3f
171 N6f06ad18b9e3468d912f6188a0d33658 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name Humans
173 rdf:type schema:DefinedTerm
174 N71c3b075154b42ff948d0318602ed9d5 schema:name Springer Nature - SN SciGraph project
175 rdf:type schema:Organization
176 N71d303b485a14a1dae8cacd484aabeda schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Age of Onset
178 rdf:type schema:DefinedTerm
179 N8438d44e90d54ceb8768d83c8264cff6 schema:issueNumber 1
180 rdf:type schema:PublicationIssue
181 N8ec9e2b4a3634a9aade24152b5f8ae73 rdf:first sg:person.01250325465.63
182 rdf:rest N1bec5db3e8214274adfa448e240506b1
183 N98ddd38afa474d169f7ced3b22e221d7 rdf:first sg:person.01042010110.29
184 rdf:rest rdf:nil
185 Na51f04aaad5549799aee2f2b0ca04fc3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Survival Rate
187 rdf:type schema:DefinedTerm
188 Nb1626180e5844c99b439f40d77095ebe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name Prognosis
190 rdf:type schema:DefinedTerm
191 Nd2b03485c0054058a1a84ab7824a692b schema:name doi
192 schema:value 10.1007/s00535-011-0490-y
193 rdf:type schema:PropertyValue
194 Nd2b1235bf0cb495ba204af8d2c00f81e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
195 schema:name Esophageal Neoplasms
196 rdf:type schema:DefinedTerm
197 Ne68a100af84b47fbb180302a66361a75 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
198 schema:name Diagnosis, Differential
199 rdf:type schema:DefinedTerm
200 Neb70196cf53648a697e7c9e791509b3f rdf:first sg:person.0725561510.49
201 rdf:rest Nf897108c654b44389e01925d0412dd25
202 Nf6ad1f2fb540403a911b7518be0b896f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
203 schema:name Sex Factors
204 rdf:type schema:DefinedTerm
205 Nf897108c654b44389e01925d0412dd25 rdf:first sg:person.0657446310.30
206 rdf:rest N8ec9e2b4a3634a9aade24152b5f8ae73
207 Nfdc680fd19ed40e7afbba306b0bb16b4 schema:name pubmed_id
208 schema:value 22048255
209 rdf:type schema:PropertyValue
210 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
211 schema:name Medical and Health Sciences
212 rdf:type schema:DefinedTerm
213 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
214 schema:name Oncology and Carcinogenesis
215 rdf:type schema:DefinedTerm
216 sg:journal.1009747 schema:issn 0944-1174
217 1435-5922
218 schema:name Journal of Gastroenterology
219 schema:publisher Springer Nature
220 rdf:type schema:Periodical
221 sg:person.01026010244.03 schema:affiliation grid-institutes:grid.258269.2
222 schema:familyName Iwanuma
223 schema:givenName Yoshimi
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01026010244.03
225 rdf:type schema:Person
226 sg:person.01042010110.29 schema:affiliation grid-institutes:grid.258269.2
227 schema:familyName Kajiyama
228 schema:givenName Yoshiaki
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01042010110.29
230 rdf:type schema:Person
231 sg:person.01250325465.63 schema:affiliation grid-institutes:grid.258269.2
232 schema:familyName Isayama
233 schema:givenName Fuyumi
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250325465.63
235 rdf:type schema:Person
236 sg:person.0606062302.32 schema:affiliation grid-institutes:grid.258269.2
237 schema:familyName Hayashi
238 schema:givenName Takuo
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0606062302.32
240 rdf:type schema:Person
241 sg:person.0623006417.52 schema:affiliation grid-institutes:grid.258269.2
242 schema:familyName Tsurumaru
243 schema:givenName Masahiko
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623006417.52
245 rdf:type schema:Person
246 sg:person.0657446310.30 schema:affiliation grid-institutes:grid.258269.2
247 schema:familyName Amano
248 schema:givenName Takayuki
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657446310.30
250 rdf:type schema:Person
251 sg:person.0725561510.49 schema:affiliation grid-institutes:grid.258269.2
252 schema:familyName Tomita
253 schema:givenName Natsumi
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725561510.49
255 rdf:type schema:Person
256 sg:pub.10.1007/bf01606502 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027113988
257 https://doi.org/10.1007/bf01606502
258 rdf:type schema:CreativeWork
259 sg:pub.10.1007/bf02190531 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007231419
260 https://doi.org/10.1007/bf02190531
261 rdf:type schema:CreativeWork
262 sg:pub.10.1007/s004280000220 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023343732
263 https://doi.org/10.1007/s004280000220
264 rdf:type schema:CreativeWork
265 sg:pub.10.1007/s10388-009-0169-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036942194
266 https://doi.org/10.1007/s10388-009-0169-0
267 rdf:type schema:CreativeWork
268 sg:pub.10.1007/s11605-007-0417-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043541960
269 https://doi.org/10.1007/s11605-007-0417-3
270 rdf:type schema:CreativeWork
271 sg:pub.10.1023/b:ddas.0000043379.60295.cb schema:sameAs https://app.dimensions.ai/details/publication/pub.1051410532
272 https://doi.org/10.1023/b:ddas.0000043379.60295.cb
273 rdf:type schema:CreativeWork
274 grid-institutes:grid.258269.2 schema:alternateName Cancer Center, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan
275 Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan
276 Department of Human Pathology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan
277 schema:name Cancer Center, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan
278 Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan
279 Department of Human Pathology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan
280 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...