Management and outcome of peptic ulcers or erosions in patients receiving a combination of aspirin plus clopidogrel View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-09

AUTHORS

Fook Hong Ng, Pierre Chan, Chi Pong Kwanching, Ching Kong Loo, Ting Kin Cheung, Siu Yin Wong, Carolyn Kng, Ka Man Ng, Sik To Lai, Benjamin Chun Yu Wong

ABSTRACT

BACKGROUND: This multicenter retrospective study investigated the management and outcome of patients with peptic ulcer/erosion-related aspirin and clopidogrel (A + C) cotherapy. METHODS: From January 2002 to September 2006, patients with endoscopically proven peptic ulcers/erosions after receiving A + C cotherapy were analyzed. RESULTS: This group consisted of 106 patients (age, 69.3 +/- 11.7 years). Ulcers/erosions developed in 27 patients during hospitalization for cardiac events and in 79 patients after hospital discharge. Of 27 patients hospitalized for acute cardiac events, gastrointestinal (GI) bleeding and dyspepsia occurred in 24 and three, respectively. The most common lesion was gastric ulcer. Of 79 discharged patients, GI bleeding and dyspepsia occurred in 64 and 15, respectively. The most common bleeding and dyspeptic lesions were gastric ulcer and gastritis, respectively. Overall, 17 patients underwent endoscopic hemostasis all successfully. A + C cotherapy was continued in 57 patients for a median (interquartile range) of 3.0 (6.2) months. Most were coprescribed a proton pump inhibitor (PPI) (53, 93%). No recurrent GI bleeding was observed. CONCLUSIONS: After A + C cotherapy, gastric ulcer or gastritis were the most common endoscopic lesions. The combination of a PPI and endoscopic treatment for ulcer bleeding was highly successful. After patient stabilization, continuation of A + C cotherapy with a PPI appears to be safe. More... »

PAGES

679-686

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00535-008-2215-4

DOI

http://dx.doi.org/10.1007/s00535-008-2215-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1014057074

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18807129


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Inflammatory Agents, Non-Steroidal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aspirin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Clopidogrel", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Coronary Disease", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gastrointestinal Hemorrhage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hemostasis, Endoscopic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hospitalization", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Peptic Ulcer", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Platelet Aggregation Inhibitors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Stents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ticlopidine", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Ruttonjee Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416291.9", 
          "name": [
            "Department of Medicine & Surgery, Ruttonjee Hospital, 266 Queen\u2019s Road East, Wai Chai, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ng", 
        "givenName": "Fook Hong", 
        "id": "sg:person.015465254072.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015465254072.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chan", 
        "givenName": "Pierre", 
        "id": "sg:person.07742761162.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07742761162.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Princess Margaret Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415229.9", 
          "name": [
            "Department of Medicine, Princess Margaret Hospital, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kwanching", 
        "givenName": "Chi Pong", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kwong Wah Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415591.d", 
          "name": [
            "Department of Medicine, Kwong Wah Hospital, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Loo", 
        "givenName": "Ching Kong", 
        "id": "sg:person.011015005142.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011015005142.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cheung", 
        "givenName": "Ting Kin", 
        "id": "sg:person.0600316650.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600316650.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ruttonjee Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416291.9", 
          "name": [
            "Department of Medicine & Surgery, Ruttonjee Hospital, 266 Queen\u2019s Road East, Wai Chai, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wong", 
        "givenName": "Siu Yin", 
        "id": "sg:person.0710766245.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710766245.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ruttonjee Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416291.9", 
          "name": [
            "Department of Medicine & Surgery, Ruttonjee Hospital, 266 Queen\u2019s Road East, Wai Chai, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kng", 
        "givenName": "Carolyn", 
        "id": "sg:person.0757101445.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757101445.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Princess Margaret Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415229.9", 
          "name": [
            "Department of Medicine, Princess Margaret Hospital, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ng", 
        "givenName": "Ka Man", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Princess Margaret Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415229.9", 
          "name": [
            "Department of Medicine, Princess Margaret Hospital, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lai", 
        "givenName": "Sik To", 
        "id": "sg:person.010505571662.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010505571662.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wong", 
        "givenName": "Benjamin Chun Yu", 
        "id": "sg:person.013726725412.80", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013726725412.80"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s0002-9343(99)80159-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004785085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jtcvs.2004.02.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007945986"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0735-1097(94)00462-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011265146"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmp068234", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014764820"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa050522", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028133368"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa051379", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030519571"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000141264", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031575386"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9343(98)00363-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031587027"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.104.522425", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034323361"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1572-0241.2007.01715.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034492141", 
          "https://doi.org/10.1111/j.1572-0241.2007.01715.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.288.19.2411", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036071844"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199906173402407", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036097831"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(05)67660-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037668020"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.38947.697558.ae", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038413139"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0735-1097(88)90158-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039122778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(01)05701-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040456834"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1572-0241.2007.01460.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041604912", 
          "https://doi.org/10.1111/j.1572-0241.2007.01460.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa010746", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042739677"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.106.618066", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043183059"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.amjmed.2006.01.023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051667614"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.106.612812", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052919720"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077112554", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082806947", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-09", 
    "datePublishedReg": "2008-09-01", 
    "description": "BACKGROUND: This multicenter retrospective study investigated the management and outcome of patients with peptic ulcer/erosion-related aspirin and clopidogrel (A + C) cotherapy.\nMETHODS: From January 2002 to September 2006, patients with endoscopically proven peptic ulcers/erosions after receiving A + C cotherapy were analyzed.\nRESULTS: This group consisted of 106 patients (age, 69.3 +/- 11.7 years). Ulcers/erosions developed in 27 patients during hospitalization for cardiac events and in 79 patients after hospital discharge. Of 27 patients hospitalized for acute cardiac events, gastrointestinal (GI) bleeding and dyspepsia occurred in 24 and three, respectively. The most common lesion was gastric ulcer. Of 79 discharged patients, GI bleeding and dyspepsia occurred in 64 and 15, respectively. The most common bleeding and dyspeptic lesions were gastric ulcer and gastritis, respectively. Overall, 17 patients underwent endoscopic hemostasis all successfully. A + C cotherapy was continued in 57 patients for a median (interquartile range) of 3.0 (6.2) months. Most were coprescribed a proton pump inhibitor (PPI) (53, 93%). No recurrent GI bleeding was observed.\nCONCLUSIONS: After A + C cotherapy, gastric ulcer or gastritis were the most common endoscopic lesions. The combination of a PPI and endoscopic treatment for ulcer bleeding was highly successful. After patient stabilization, continuation of A + C cotherapy with a PPI appears to be safe.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00535-008-2215-4", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1009747", 
        "issn": [
          "0944-1174", 
          "1435-5922"
        ], 
        "name": "Journal of Gastroenterology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "9", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "43"
      }
    ], 
    "name": "Management and outcome of peptic ulcers or erosions in patients receiving a combination of aspirin plus clopidogrel", 
    "pagination": "679-686", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "42f703c2b5daff3aaffc5da4e4ca66e6baf5669199966fac6f6a72540dbb7d9e"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18807129"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9430794"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00535-008-2215-4"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1014057074"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00535-008-2215-4", 
      "https://app.dimensions.ai/details/publication/pub.1014057074"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T14:34", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000373_0000000373/records_13109_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00535-008-2215-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00535-008-2215-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00535-008-2215-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00535-008-2215-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00535-008-2215-4'


 

This table displays all metadata directly associated to this object as RDF triples.

271 TRIPLES      21 PREDICATES      67 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00535-008-2215-4 schema:about N2361db037e2f46f29b14226f243abd0c
2 N316d6c43cf1c4f34802f791377994f3b
3 N387e2b39fe6046af9f6fda7fa8a3550c
4 N45a1bd91ddd942c28f0fda337e44e526
5 N55e62e1b44f34ed09b70d641d09deb70
6 N584110e121d44272a3a8056e0f4a7055
7 N641e589a5f8d4f399109c22159454788
8 N8e4cb68ebb6f497b8cf26c87d7a1f276
9 N946467aee1474d048f1e47be6fdd76de
10 Nc41793e7c53a493a81b47b613ad6dc52
11 Ne83beb15ce154ad4a66e6381a51dbc61
12 Ne8dfd6df289c40dfb6ab048cf2b53cde
13 Nf9d0626b29ae4aa6a64a284a219c915b
14 Nfdc3e295dffe44b093243430464b946a
15 Nffda1af037b84b3f91b5f6590b536a3c
16 anzsrc-for:11
17 anzsrc-for:1103
18 schema:author Nac5f0d477b144e8e9c0c9f57b8188ca2
19 schema:citation sg:pub.10.1111/j.1572-0241.2007.01460.x
20 sg:pub.10.1111/j.1572-0241.2007.01715.x
21 https://app.dimensions.ai/details/publication/pub.1077112554
22 https://app.dimensions.ai/details/publication/pub.1082806947
23 https://doi.org/10.1001/jama.288.19.2411
24 https://doi.org/10.1016/0735-1097(88)90158-1
25 https://doi.org/10.1016/0735-1097(94)00462-y
26 https://doi.org/10.1016/j.amjmed.2006.01.023
27 https://doi.org/10.1016/j.jtcvs.2004.02.019
28 https://doi.org/10.1016/s0002-9343(98)00363-5
29 https://doi.org/10.1016/s0002-9343(99)80159-4
30 https://doi.org/10.1016/s0140-6736(01)05701-4
31 https://doi.org/10.1016/s0140-6736(05)67660-x
32 https://doi.org/10.1056/nejm199906173402407
33 https://doi.org/10.1056/nejmoa010746
34 https://doi.org/10.1056/nejmoa050522
35 https://doi.org/10.1056/nejmoa051379
36 https://doi.org/10.1056/nejmp068234
37 https://doi.org/10.1136/bmj.38947.697558.ae
38 https://doi.org/10.1159/000141264
39 https://doi.org/10.1161/circulationaha.104.522425
40 https://doi.org/10.1161/circulationaha.106.612812
41 https://doi.org/10.1161/circulationaha.106.618066
42 schema:datePublished 2008-09
43 schema:datePublishedReg 2008-09-01
44 schema:description BACKGROUND: This multicenter retrospective study investigated the management and outcome of patients with peptic ulcer/erosion-related aspirin and clopidogrel (A + C) cotherapy. METHODS: From January 2002 to September 2006, patients with endoscopically proven peptic ulcers/erosions after receiving A + C cotherapy were analyzed. RESULTS: This group consisted of 106 patients (age, 69.3 +/- 11.7 years). Ulcers/erosions developed in 27 patients during hospitalization for cardiac events and in 79 patients after hospital discharge. Of 27 patients hospitalized for acute cardiac events, gastrointestinal (GI) bleeding and dyspepsia occurred in 24 and three, respectively. The most common lesion was gastric ulcer. Of 79 discharged patients, GI bleeding and dyspepsia occurred in 64 and 15, respectively. The most common bleeding and dyspeptic lesions were gastric ulcer and gastritis, respectively. Overall, 17 patients underwent endoscopic hemostasis all successfully. A + C cotherapy was continued in 57 patients for a median (interquartile range) of 3.0 (6.2) months. Most were coprescribed a proton pump inhibitor (PPI) (53, 93%). No recurrent GI bleeding was observed. CONCLUSIONS: After A + C cotherapy, gastric ulcer or gastritis were the most common endoscopic lesions. The combination of a PPI and endoscopic treatment for ulcer bleeding was highly successful. After patient stabilization, continuation of A + C cotherapy with a PPI appears to be safe.
45 schema:genre research_article
46 schema:inLanguage en
47 schema:isAccessibleForFree false
48 schema:isPartOf N29007b4066c747f3b5e4ccdd3128e540
49 N824c0cfbde374633800bc38c7608b8cc
50 sg:journal.1009747
51 schema:name Management and outcome of peptic ulcers or erosions in patients receiving a combination of aspirin plus clopidogrel
52 schema:pagination 679-686
53 schema:productId N5fe1a57999dd4032aa04bf39782f0fd0
54 N99ee6b2e3b374c0d98d641a889049274
55 Nafe032823bd148e2a75c70d8450e0568
56 Nb43373780bf04101b20d903748adb39b
57 Nd7e132ec3da247548ac0a9c39ad5a050
58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014057074
59 https://doi.org/10.1007/s00535-008-2215-4
60 schema:sdDatePublished 2019-04-11T14:34
61 schema:sdLicense https://scigraph.springernature.com/explorer/license/
62 schema:sdPublisher N59303a1b304445ce8b59ffad81763866
63 schema:url http://link.springer.com/10.1007%2Fs00535-008-2215-4
64 sgo:license sg:explorer/license/
65 sgo:sdDataset articles
66 rdf:type schema:ScholarlyArticle
67 N01c81c3f14ba4976ae17cabff290acbe rdf:first sg:person.011015005142.62
68 rdf:rest Na9c16cea55e9474ebf2cd09648a0eb91
69 N2361db037e2f46f29b14226f243abd0c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
70 schema:name Stents
71 rdf:type schema:DefinedTerm
72 N29007b4066c747f3b5e4ccdd3128e540 schema:volumeNumber 43
73 rdf:type schema:PublicationVolume
74 N316d6c43cf1c4f34802f791377994f3b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Anti-Inflammatory Agents, Non-Steroidal
76 rdf:type schema:DefinedTerm
77 N387e2b39fe6046af9f6fda7fa8a3550c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Peptic Ulcer
79 rdf:type schema:DefinedTerm
80 N427815f4c08e40839c15539b7c678af7 rdf:first sg:person.0757101445.46
81 rdf:rest N96feb93c87fc45be917d6f3453e5a125
82 N44eb47eba2724231a53180651284ea05 schema:name Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
83 rdf:type schema:Organization
84 N45a1bd91ddd942c28f0fda337e44e526 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Male
86 rdf:type schema:DefinedTerm
87 N52bfadbb1429411ea1927e5a3cdd2b07 schema:name Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
88 rdf:type schema:Organization
89 N55e62e1b44f34ed09b70d641d09deb70 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Aspirin
91 rdf:type schema:DefinedTerm
92 N584110e121d44272a3a8056e0f4a7055 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Humans
94 rdf:type schema:DefinedTerm
95 N59303a1b304445ce8b59ffad81763866 schema:name Springer Nature - SN SciGraph project
96 rdf:type schema:Organization
97 N5a31463ea5cb4c64be7e2486ef7574f3 schema:affiliation https://www.grid.ac/institutes/grid.415229.9
98 schema:familyName Ng
99 schema:givenName Ka Man
100 rdf:type schema:Person
101 N5c96b4ec98524ce8a55f7ebf21920435 rdf:first sg:person.010505571662.88
102 rdf:rest Na734c4ceafa240ce90d299fd28e7e82d
103 N5fe1a57999dd4032aa04bf39782f0fd0 schema:name doi
104 schema:value 10.1007/s00535-008-2215-4
105 rdf:type schema:PropertyValue
106 N641e589a5f8d4f399109c22159454788 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Hemostasis, Endoscopic
108 rdf:type schema:DefinedTerm
109 N7fc534094cc04471b8e216797ec5e7d2 rdf:first sg:person.07742761162.25
110 rdf:rest Nd693d7d7da19436abefb8fa57a3665c9
111 N80dbb872bb3d4f6daa07bad62c51d090 schema:affiliation https://www.grid.ac/institutes/grid.415229.9
112 schema:familyName Kwanching
113 schema:givenName Chi Pong
114 rdf:type schema:Person
115 N824c0cfbde374633800bc38c7608b8cc schema:issueNumber 9
116 rdf:type schema:PublicationIssue
117 N89a7840684dc4b518ffdf5ff67ddca5d rdf:first sg:person.0710766245.58
118 rdf:rest N427815f4c08e40839c15539b7c678af7
119 N8e4cb68ebb6f497b8cf26c87d7a1f276 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Female
121 rdf:type schema:DefinedTerm
122 N946467aee1474d048f1e47be6fdd76de schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Hospitalization
124 rdf:type schema:DefinedTerm
125 N96feb93c87fc45be917d6f3453e5a125 rdf:first N5a31463ea5cb4c64be7e2486ef7574f3
126 rdf:rest N5c96b4ec98524ce8a55f7ebf21920435
127 N99ee6b2e3b374c0d98d641a889049274 schema:name readcube_id
128 schema:value 42f703c2b5daff3aaffc5da4e4ca66e6baf5669199966fac6f6a72540dbb7d9e
129 rdf:type schema:PropertyValue
130 Na734c4ceafa240ce90d299fd28e7e82d rdf:first sg:person.013726725412.80
131 rdf:rest rdf:nil
132 Na9c16cea55e9474ebf2cd09648a0eb91 rdf:first sg:person.0600316650.51
133 rdf:rest N89a7840684dc4b518ffdf5ff67ddca5d
134 Nac5f0d477b144e8e9c0c9f57b8188ca2 rdf:first sg:person.015465254072.15
135 rdf:rest N7fc534094cc04471b8e216797ec5e7d2
136 Nafe032823bd148e2a75c70d8450e0568 schema:name pubmed_id
137 schema:value 18807129
138 rdf:type schema:PropertyValue
139 Nb43373780bf04101b20d903748adb39b schema:name dimensions_id
140 schema:value pub.1014057074
141 rdf:type schema:PropertyValue
142 Nc41793e7c53a493a81b47b613ad6dc52 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Coronary Disease
144 rdf:type schema:DefinedTerm
145 Nd693d7d7da19436abefb8fa57a3665c9 rdf:first N80dbb872bb3d4f6daa07bad62c51d090
146 rdf:rest N01c81c3f14ba4976ae17cabff290acbe
147 Nd7e132ec3da247548ac0a9c39ad5a050 schema:name nlm_unique_id
148 schema:value 9430794
149 rdf:type schema:PropertyValue
150 Ne83beb15ce154ad4a66e6381a51dbc61 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Gastrointestinal Hemorrhage
152 rdf:type schema:DefinedTerm
153 Ne8dfd6df289c40dfb6ab048cf2b53cde schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Ticlopidine
155 rdf:type schema:DefinedTerm
156 Nf9d0626b29ae4aa6a64a284a219c915b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Clopidogrel
158 rdf:type schema:DefinedTerm
159 Nfbafa0c44200417e94c7e69ff8e1d220 schema:name Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
160 rdf:type schema:Organization
161 Nfdc3e295dffe44b093243430464b946a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Aged
163 rdf:type schema:DefinedTerm
164 Nffda1af037b84b3f91b5f6590b536a3c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Platelet Aggregation Inhibitors
166 rdf:type schema:DefinedTerm
167 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
168 schema:name Medical and Health Sciences
169 rdf:type schema:DefinedTerm
170 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
171 schema:name Clinical Sciences
172 rdf:type schema:DefinedTerm
173 sg:journal.1009747 schema:issn 0944-1174
174 1435-5922
175 schema:name Journal of Gastroenterology
176 rdf:type schema:Periodical
177 sg:person.010505571662.88 schema:affiliation https://www.grid.ac/institutes/grid.415229.9
178 schema:familyName Lai
179 schema:givenName Sik To
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010505571662.88
181 rdf:type schema:Person
182 sg:person.011015005142.62 schema:affiliation https://www.grid.ac/institutes/grid.415591.d
183 schema:familyName Loo
184 schema:givenName Ching Kong
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011015005142.62
186 rdf:type schema:Person
187 sg:person.013726725412.80 schema:affiliation N52bfadbb1429411ea1927e5a3cdd2b07
188 schema:familyName Wong
189 schema:givenName Benjamin Chun Yu
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013726725412.80
191 rdf:type schema:Person
192 sg:person.015465254072.15 schema:affiliation https://www.grid.ac/institutes/grid.416291.9
193 schema:familyName Ng
194 schema:givenName Fook Hong
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015465254072.15
196 rdf:type schema:Person
197 sg:person.0600316650.51 schema:affiliation Nfbafa0c44200417e94c7e69ff8e1d220
198 schema:familyName Cheung
199 schema:givenName Ting Kin
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600316650.51
201 rdf:type schema:Person
202 sg:person.0710766245.58 schema:affiliation https://www.grid.ac/institutes/grid.416291.9
203 schema:familyName Wong
204 schema:givenName Siu Yin
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710766245.58
206 rdf:type schema:Person
207 sg:person.0757101445.46 schema:affiliation https://www.grid.ac/institutes/grid.416291.9
208 schema:familyName Kng
209 schema:givenName Carolyn
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757101445.46
211 rdf:type schema:Person
212 sg:person.07742761162.25 schema:affiliation N44eb47eba2724231a53180651284ea05
213 schema:familyName Chan
214 schema:givenName Pierre
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07742761162.25
216 rdf:type schema:Person
217 sg:pub.10.1111/j.1572-0241.2007.01460.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1041604912
218 https://doi.org/10.1111/j.1572-0241.2007.01460.x
219 rdf:type schema:CreativeWork
220 sg:pub.10.1111/j.1572-0241.2007.01715.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034492141
221 https://doi.org/10.1111/j.1572-0241.2007.01715.x
222 rdf:type schema:CreativeWork
223 https://app.dimensions.ai/details/publication/pub.1077112554 schema:CreativeWork
224 https://app.dimensions.ai/details/publication/pub.1082806947 schema:CreativeWork
225 https://doi.org/10.1001/jama.288.19.2411 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036071844
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1016/0735-1097(88)90158-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039122778
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1016/0735-1097(94)00462-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1011265146
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1016/j.amjmed.2006.01.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051667614
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1016/j.jtcvs.2004.02.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007945986
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1016/s0002-9343(98)00363-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031587027
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1016/s0002-9343(99)80159-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004785085
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1016/s0140-6736(01)05701-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040456834
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1016/s0140-6736(05)67660-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1037668020
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1056/nejm199906173402407 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036097831
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1056/nejmoa010746 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042739677
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1056/nejmoa050522 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028133368
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1056/nejmoa051379 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030519571
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1056/nejmp068234 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014764820
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1136/bmj.38947.697558.ae schema:sameAs https://app.dimensions.ai/details/publication/pub.1038413139
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1159/000141264 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031575386
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1161/circulationaha.104.522425 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034323361
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1161/circulationaha.106.612812 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052919720
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1161/circulationaha.106.618066 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043183059
262 rdf:type schema:CreativeWork
263 https://www.grid.ac/institutes/grid.415229.9 schema:alternateName Princess Margaret Hospital
264 schema:name Department of Medicine, Princess Margaret Hospital, Hong Kong, China
265 rdf:type schema:Organization
266 https://www.grid.ac/institutes/grid.415591.d schema:alternateName Kwong Wah Hospital
267 schema:name Department of Medicine, Kwong Wah Hospital, Hong Kong, China
268 rdf:type schema:Organization
269 https://www.grid.ac/institutes/grid.416291.9 schema:alternateName Ruttonjee Hospital
270 schema:name Department of Medicine & Surgery, Ruttonjee Hospital, 266 Queen’s Road East, Wai Chai, Hong Kong, China
271 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...