Phenotypic alteration of interstitial cells of Cajal in idiopathic sigmoid megacolon View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-08-17

AUTHORS

Yasushi Adachi, Yoshifumi Ishii, Mitsuru Yoshimoto, Yukinari Yoshida, Takao Endo, Hiroyuki Yamamoto, Hirofumi Akashi, Kohzoh Imai, Yasuhisa Shinomura, Yasuo Kato

ABSTRACT

BackgroundInterstitial cells of Cajal (ICCs) are detected as a pacemaker of gastrointestinal movement and express c-kit and CD34. Recently, ICCs have implicated pathogenesis in several human diseases presenting gastrointestinal motor dysfunction. This study was performed to clarify the role of ICCs in idiopathic sigmoid megacolon using histological and immunohistochemical examinations.MethodsFour adult patients with idiopathic sigmoid megacolon and 11 controls were studied. Histology and immunocytochemistry using NSE, S100, c-kit, and CD34 were performed in conjunction with quantitative analysis using the public domain NIH image program.ResultsLittle histological change in neuromuscular structures in megacolon was observed. Immunohistochemistry demonstrated remarkable decrease of c-kit expressing ICCs without reduction of CD34 expression in the similar interstitial cell population. This observation was further supported by quantitative assessment using public domain NIH image program.ConclusionsA specific downregulation of c-kit in ICCs may be a cause of idiopathic sigmoid megacolon in adults. More... »

PAGES

626-631

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00535-008-2207-4

DOI

http://dx.doi.org/10.1007/s00535-008-2207-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1044150512

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18709485


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antigens, CD34", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colonoscopy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diagnosis, Differential", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Enteric Nervous System", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunohistochemistry", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Megacolon", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phenotype", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proto-Oncogene Proteins c-kit", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sigmoid Diseases", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.263171.0", 
          "name": [
            "Internal Medicine, Sapporo Shirakabadai Hospital, 2-18 Higashi Tsukisamu, Toyohira-ku, 062-0052, Sapporo, Japan", 
            "First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Adachi", 
        "givenName": "Yasushi", 
        "id": "sg:person.01110335104.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110335104.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pathology, Sapporo Shirakabadai Hospital, Sapporo, Japan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Pathology, Sapporo Shirakabadai Hospital, Sapporo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ishii", 
        "givenName": "Yoshifumi", 
        "id": "sg:person.01117776047.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117776047.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Second Department of Internal Medicine, Tenshi Hospital, Sapporo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.416956.9", 
          "name": [
            "Second Department of Internal Medicine, Tenshi Hospital, Sapporo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yoshimoto", 
        "givenName": "Mitsuru", 
        "id": "sg:person.01226143463.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01226143463.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Internal Medicine, Doto Hospital, Sapporo, Japan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Internal Medicine, Doto Hospital, Sapporo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yoshida", 
        "givenName": "Yukinari", 
        "id": "sg:person.0710655422.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710655422.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Internal Medicine, Sapporo Shirakabadai Hospital, 2-18 Higashi Tsukisamu, Toyohira-ku, 062-0052, Sapporo, Japan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Internal Medicine, Sapporo Shirakabadai Hospital, 2-18 Higashi Tsukisamu, Toyohira-ku, 062-0052, Sapporo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Endo", 
        "givenName": "Takao", 
        "id": "sg:person.01146377371.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146377371.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.263171.0", 
          "name": [
            "First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yamamoto", 
        "givenName": "Hiroyuki", 
        "id": "sg:person.0635431612.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635431612.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.263171.0", 
          "name": [
            "First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Akashi", 
        "givenName": "Hirofumi", 
        "id": "sg:person.01121365646.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121365646.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.263171.0", 
          "name": [
            "First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Imai", 
        "givenName": "Kohzoh", 
        "id": "sg:person.0762051764.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0762051764.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.263171.0", 
          "name": [
            "First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shinomura", 
        "givenName": "Yasuhisa", 
        "id": "sg:person.0643127340.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643127340.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Internal Medicine, Sapporo Shirakabadai Hospital, 2-18 Higashi Tsukisamu, Toyohira-ku, 062-0052, Sapporo, Japan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Internal Medicine, Sapporo Shirakabadai Hospital, 2-18 Higashi Tsukisamu, Toyohira-ku, 062-0052, Sapporo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kato", 
        "givenName": "Yasuo", 
        "id": "sg:person.01205407430.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01205407430.75"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00535-006-1909-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029857573", 
          "https://doi.org/10.1007/s00535-006-1909-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00304515", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002124690", 
          "https://doi.org/10.1007/bf00304515"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-08-17", 
    "datePublishedReg": "2008-08-17", 
    "description": "BackgroundInterstitial cells of Cajal (ICCs) are detected as a pacemaker of gastrointestinal movement and express c-kit and CD34. Recently, ICCs have implicated pathogenesis in several human diseases presenting gastrointestinal motor dysfunction. This study was performed to clarify the role of ICCs in idiopathic sigmoid megacolon using histological and immunohistochemical examinations.MethodsFour adult patients with idiopathic sigmoid megacolon and 11 controls were studied. Histology and immunocytochemistry using NSE, S100, c-kit, and CD34 were performed in conjunction with quantitative analysis using the public domain NIH image program.ResultsLittle histological change in neuromuscular structures in megacolon was observed. Immunohistochemistry demonstrated remarkable decrease of c-kit expressing ICCs without reduction of CD34 expression in the similar interstitial cell population. This observation was further supported by quantitative assessment using public domain NIH image program.ConclusionsA specific downregulation of c-kit in ICCs may be a cause of idiopathic sigmoid megacolon in adults.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00535-008-2207-4", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1009747", 
        "issn": [
          "0944-1174", 
          "1435-5922"
        ], 
        "name": "Journal of Gastroenterology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "8", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "43"
      }
    ], 
    "keywords": [
      "c-kit", 
      "NIH Image program", 
      "gastrointestinal motor dysfunction", 
      "role of ICC", 
      "gastrointestinal movement", 
      "adult patients", 
      "motor dysfunction", 
      "immunohistochemical examination", 
      "express c-kit", 
      "histological changes", 
      "CD34 expression", 
      "megacolon", 
      "public domain NIH Image program", 
      "interstitial cell population", 
      "interstitial cells", 
      "neuromuscular structures", 
      "image program", 
      "specific downregulation", 
      "cell populations", 
      "Cajal", 
      "CD34", 
      "ICC", 
      "phenotypic alterations", 
      "human diseases", 
      "cells", 
      "patients", 
      "dysfunction", 
      "pathogenesis", 
      "immunohistochemistry", 
      "histology", 
      "remarkable decrease", 
      "quantitative assessment", 
      "disease", 
      "S100", 
      "immunocytochemistry", 
      "pacemaker", 
      "downregulation", 
      "adults", 
      "cause", 
      "examination", 
      "alterations", 
      "NSE", 
      "expression", 
      "population", 
      "program", 
      "assessment", 
      "decrease", 
      "control", 
      "study", 
      "quantitative analysis", 
      "role", 
      "reduction", 
      "changes", 
      "conjunction", 
      "analysis", 
      "movement", 
      "observations", 
      "structure"
    ], 
    "name": "Phenotypic alteration of interstitial cells of Cajal in idiopathic sigmoid megacolon", 
    "pagination": "626-631", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1044150512"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00535-008-2207-4"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18709485"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00535-008-2207-4", 
      "https://app.dimensions.ai/details/publication/pub.1044150512"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-08-04T16:57", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_465.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00535-008-2207-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00535-008-2207-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00535-008-2207-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00535-008-2207-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00535-008-2207-4'


 

This table displays all metadata directly associated to this object as RDF triples.

257 TRIPLES      21 PREDICATES      99 URIs      89 LITERALS      21 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00535-008-2207-4 schema:about N1fb6c7c0f34b40c185a6f20c9a2bef9a
2 N26ec645cb9564ee98ae871debf007a8d
3 N3cd3b858610a4a2eb7653ee47f6f6cd3
4 N6f6098d0580d41969051010eac32a187
5 N7ad161d9afef4597b496eda33cd2310b
6 N85f734a501454700bf97c4dc7f141287
7 N91d59c21dc9745a9b270d2c37b224c1f
8 Nac6c20843c774e258ac2042e20c41972
9 Nb16662b2a9ef4e57b5c801df25dc43a4
10 Nbb6b7f0163a54596b1e80593de171ea1
11 Nca3984e5ce744213b65a52b5f8e67d26
12 Nca818fbdbe90441b97f9ca867220263d
13 Nefe84669571a470285b96fff5e3f369a
14 Nf58aaf9b8a354aceba9b86e79f178d20
15 anzsrc-for:11
16 anzsrc-for:1103
17 schema:author N97a6cddd926c40e2827da4708ca00f7f
18 schema:citation sg:pub.10.1007/bf00304515
19 sg:pub.10.1007/s00535-006-1909-8
20 schema:datePublished 2008-08-17
21 schema:datePublishedReg 2008-08-17
22 schema:description BackgroundInterstitial cells of Cajal (ICCs) are detected as a pacemaker of gastrointestinal movement and express c-kit and CD34. Recently, ICCs have implicated pathogenesis in several human diseases presenting gastrointestinal motor dysfunction. This study was performed to clarify the role of ICCs in idiopathic sigmoid megacolon using histological and immunohistochemical examinations.MethodsFour adult patients with idiopathic sigmoid megacolon and 11 controls were studied. Histology and immunocytochemistry using NSE, S100, c-kit, and CD34 were performed in conjunction with quantitative analysis using the public domain NIH image program.ResultsLittle histological change in neuromuscular structures in megacolon was observed. Immunohistochemistry demonstrated remarkable decrease of c-kit expressing ICCs without reduction of CD34 expression in the similar interstitial cell population. This observation was further supported by quantitative assessment using public domain NIH image program.ConclusionsA specific downregulation of c-kit in ICCs may be a cause of idiopathic sigmoid megacolon in adults.
23 schema:genre article
24 schema:isAccessibleForFree false
25 schema:isPartOf N8098ac89c02d48daa799ea9607515a83
26 Nfae10671052b4b489e00f8bdd0338526
27 sg:journal.1009747
28 schema:keywords CD34
29 CD34 expression
30 Cajal
31 ICC
32 NIH Image program
33 NSE
34 S100
35 adult patients
36 adults
37 alterations
38 analysis
39 assessment
40 c-kit
41 cause
42 cell populations
43 cells
44 changes
45 conjunction
46 control
47 decrease
48 disease
49 downregulation
50 dysfunction
51 examination
52 express c-kit
53 expression
54 gastrointestinal motor dysfunction
55 gastrointestinal movement
56 histological changes
57 histology
58 human diseases
59 image program
60 immunocytochemistry
61 immunohistochemical examination
62 immunohistochemistry
63 interstitial cell population
64 interstitial cells
65 megacolon
66 motor dysfunction
67 movement
68 neuromuscular structures
69 observations
70 pacemaker
71 pathogenesis
72 patients
73 phenotypic alterations
74 population
75 program
76 public domain NIH Image program
77 quantitative analysis
78 quantitative assessment
79 reduction
80 remarkable decrease
81 role
82 role of ICC
83 specific downregulation
84 structure
85 study
86 schema:name Phenotypic alteration of interstitial cells of Cajal in idiopathic sigmoid megacolon
87 schema:pagination 626-631
88 schema:productId N2a06fec5fd8547c187be7bfbe3d6f653
89 N7c84c34a4bb14078badcb14362528a43
90 N9a2c537469a54292b753f0017d5dd87c
91 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044150512
92 https://doi.org/10.1007/s00535-008-2207-4
93 schema:sdDatePublished 2022-08-04T16:57
94 schema:sdLicense https://scigraph.springernature.com/explorer/license/
95 schema:sdPublisher N9034b0c88dfd4d9aa264441e10d7b6e2
96 schema:url https://doi.org/10.1007/s00535-008-2207-4
97 sgo:license sg:explorer/license/
98 sgo:sdDataset articles
99 rdf:type schema:ScholarlyArticle
100 N1fb6c7c0f34b40c185a6f20c9a2bef9a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Phenotype
102 rdf:type schema:DefinedTerm
103 N26ec645cb9564ee98ae871debf007a8d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Male
105 rdf:type schema:DefinedTerm
106 N2a06fec5fd8547c187be7bfbe3d6f653 schema:name dimensions_id
107 schema:value pub.1044150512
108 rdf:type schema:PropertyValue
109 N3cd3b858610a4a2eb7653ee47f6f6cd3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Proto-Oncogene Proteins c-kit
111 rdf:type schema:DefinedTerm
112 N67ed00ed7db643709429d36c46be86c8 rdf:first sg:person.0643127340.79
113 rdf:rest Ncfe833465b6646919e5dc664fb3e7efb
114 N6f6098d0580d41969051010eac32a187 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Enteric Nervous System
116 rdf:type schema:DefinedTerm
117 N7ad161d9afef4597b496eda33cd2310b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Sigmoid Diseases
119 rdf:type schema:DefinedTerm
120 N7c84c34a4bb14078badcb14362528a43 schema:name pubmed_id
121 schema:value 18709485
122 rdf:type schema:PropertyValue
123 N8098ac89c02d48daa799ea9607515a83 schema:issueNumber 8
124 rdf:type schema:PublicationIssue
125 N85f734a501454700bf97c4dc7f141287 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Humans
127 rdf:type schema:DefinedTerm
128 N8cbe31c9ad4e4cf4ba81f159eebea925 rdf:first sg:person.01117776047.03
129 rdf:rest Nd07d90804bb2492786a533add95aebf6
130 N9034b0c88dfd4d9aa264441e10d7b6e2 schema:name Springer Nature - SN SciGraph project
131 rdf:type schema:Organization
132 N90431a193af442e28f3baef6b15c3ce5 rdf:first sg:person.01121365646.14
133 rdf:rest Ndd2a35b4d0e3489ea741d8b2660fec9b
134 N91d59c21dc9745a9b270d2c37b224c1f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Aged
136 rdf:type schema:DefinedTerm
137 N97a6cddd926c40e2827da4708ca00f7f rdf:first sg:person.01110335104.97
138 rdf:rest N8cbe31c9ad4e4cf4ba81f159eebea925
139 N9a2c537469a54292b753f0017d5dd87c schema:name doi
140 schema:value 10.1007/s00535-008-2207-4
141 rdf:type schema:PropertyValue
142 Na8faef2f208544299b840a4b5f2cd4a1 rdf:first sg:person.0635431612.98
143 rdf:rest N90431a193af442e28f3baef6b15c3ce5
144 Nabce9d014c704559b923ff2a5d09a877 rdf:first sg:person.01146377371.16
145 rdf:rest Na8faef2f208544299b840a4b5f2cd4a1
146 Nac6c20843c774e258ac2042e20c41972 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Megacolon
148 rdf:type schema:DefinedTerm
149 Nb16662b2a9ef4e57b5c801df25dc43a4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Female
151 rdf:type schema:DefinedTerm
152 Nbb6b7f0163a54596b1e80593de171ea1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Middle Aged
154 rdf:type schema:DefinedTerm
155 Nc968f3b492bc4b06be0ffab185d8efd7 rdf:first sg:person.0710655422.39
156 rdf:rest Nabce9d014c704559b923ff2a5d09a877
157 Nca3984e5ce744213b65a52b5f8e67d26 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Antigens, CD34
159 rdf:type schema:DefinedTerm
160 Nca818fbdbe90441b97f9ca867220263d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Colonoscopy
162 rdf:type schema:DefinedTerm
163 Ncfe833465b6646919e5dc664fb3e7efb rdf:first sg:person.01205407430.75
164 rdf:rest rdf:nil
165 Nd07d90804bb2492786a533add95aebf6 rdf:first sg:person.01226143463.52
166 rdf:rest Nc968f3b492bc4b06be0ffab185d8efd7
167 Ndd2a35b4d0e3489ea741d8b2660fec9b rdf:first sg:person.0762051764.57
168 rdf:rest N67ed00ed7db643709429d36c46be86c8
169 Nefe84669571a470285b96fff5e3f369a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Immunohistochemistry
171 rdf:type schema:DefinedTerm
172 Nf58aaf9b8a354aceba9b86e79f178d20 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Diagnosis, Differential
174 rdf:type schema:DefinedTerm
175 Nfae10671052b4b489e00f8bdd0338526 schema:volumeNumber 43
176 rdf:type schema:PublicationVolume
177 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
178 schema:name Medical and Health Sciences
179 rdf:type schema:DefinedTerm
180 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
181 schema:name Clinical Sciences
182 rdf:type schema:DefinedTerm
183 sg:journal.1009747 schema:issn 0944-1174
184 1435-5922
185 schema:name Journal of Gastroenterology
186 schema:publisher Springer Nature
187 rdf:type schema:Periodical
188 sg:person.01110335104.97 schema:affiliation grid-institutes:grid.263171.0
189 schema:familyName Adachi
190 schema:givenName Yasushi
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110335104.97
192 rdf:type schema:Person
193 sg:person.01117776047.03 schema:affiliation grid-institutes:None
194 schema:familyName Ishii
195 schema:givenName Yoshifumi
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117776047.03
197 rdf:type schema:Person
198 sg:person.01121365646.14 schema:affiliation grid-institutes:grid.263171.0
199 schema:familyName Akashi
200 schema:givenName Hirofumi
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121365646.14
202 rdf:type schema:Person
203 sg:person.01146377371.16 schema:affiliation grid-institutes:None
204 schema:familyName Endo
205 schema:givenName Takao
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146377371.16
207 rdf:type schema:Person
208 sg:person.01205407430.75 schema:affiliation grid-institutes:None
209 schema:familyName Kato
210 schema:givenName Yasuo
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01205407430.75
212 rdf:type schema:Person
213 sg:person.01226143463.52 schema:affiliation grid-institutes:grid.416956.9
214 schema:familyName Yoshimoto
215 schema:givenName Mitsuru
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01226143463.52
217 rdf:type schema:Person
218 sg:person.0635431612.98 schema:affiliation grid-institutes:grid.263171.0
219 schema:familyName Yamamoto
220 schema:givenName Hiroyuki
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635431612.98
222 rdf:type schema:Person
223 sg:person.0643127340.79 schema:affiliation grid-institutes:grid.263171.0
224 schema:familyName Shinomura
225 schema:givenName Yasuhisa
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643127340.79
227 rdf:type schema:Person
228 sg:person.0710655422.39 schema:affiliation grid-institutes:None
229 schema:familyName Yoshida
230 schema:givenName Yukinari
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710655422.39
232 rdf:type schema:Person
233 sg:person.0762051764.57 schema:affiliation grid-institutes:grid.263171.0
234 schema:familyName Imai
235 schema:givenName Kohzoh
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0762051764.57
237 rdf:type schema:Person
238 sg:pub.10.1007/bf00304515 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002124690
239 https://doi.org/10.1007/bf00304515
240 rdf:type schema:CreativeWork
241 sg:pub.10.1007/s00535-006-1909-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029857573
242 https://doi.org/10.1007/s00535-006-1909-8
243 rdf:type schema:CreativeWork
244 grid-institutes:None schema:alternateName Internal Medicine, Doto Hospital, Sapporo, Japan
245 Internal Medicine, Sapporo Shirakabadai Hospital, 2-18 Higashi Tsukisamu, Toyohira-ku, 062-0052, Sapporo, Japan
246 Pathology, Sapporo Shirakabadai Hospital, Sapporo, Japan
247 schema:name Internal Medicine, Doto Hospital, Sapporo, Japan
248 Internal Medicine, Sapporo Shirakabadai Hospital, 2-18 Higashi Tsukisamu, Toyohira-ku, 062-0052, Sapporo, Japan
249 Pathology, Sapporo Shirakabadai Hospital, Sapporo, Japan
250 rdf:type schema:Organization
251 grid-institutes:grid.263171.0 schema:alternateName First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan
252 schema:name First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan
253 Internal Medicine, Sapporo Shirakabadai Hospital, 2-18 Higashi Tsukisamu, Toyohira-ku, 062-0052, Sapporo, Japan
254 rdf:type schema:Organization
255 grid-institutes:grid.416956.9 schema:alternateName Second Department of Internal Medicine, Tenshi Hospital, Sapporo, Japan
256 schema:name Second Department of Internal Medicine, Tenshi Hospital, Sapporo, Japan
257 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...