Octreotide in control of multiple liver metastases from gastrinoma View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2003-09

AUTHORS

Fumito Saijo, Hiroo Naito, Yuji Funayama, Kouhei Fukushima, Chikashi Shibata, Akihiko Hashimoto, Taku Kitayama, Munenori Nagao, Seiki Matsuno, Iwao Sasaki

ABSTRACT

The somatostatin analogue octreotide was effective in controlling systemic effects related to multiple liver metastases from a gastrinoma. A 61-year-old man underwent distal gastrectomy for gastrinoma in the duodenum, because a curative resection was not feasible due to metastases found in paraaortic lymph nodes during operation. Multiple liver metastases, associated with an increase in serum gastrin concentration, were found by magnetic resonance imaging 16 months after the operation. Although chemotherapy with dimethyltrizenoimidazole carboxamide was not effective, subcutaneous administration of octreotide was effective in controlling the growth of the liver metastases and in stabilizing serum gastrin. The patient now receives subcutaneous injections of octreotide, at 200 µg a day, twice a week, as an outpatient. More... »

PAGES

905-908

References to SciGraph publications

  • 1998-11. Gastrinoma with multiple liver metastases: Effectiveness of dacarbazine (DTIC) therapy in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 1994-10. Pancreatic endocrinomas: A statistical analysis of 1,857 cases in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00535-002-1170-8

    DOI

    http://dx.doi.org/10.1007/s00535-002-1170-8

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1021131837

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/14564638


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