New-onset diabetes mellitus developing in Asian adult living donor liver transplant recipients: a single-center experience View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-04-09

AUTHORS

Nobuhiro Harada, Yasuhiko Sugawara, Nobuhisa Akamatsu, Junichi Kaneko, Sumihito Tamura, Taku Aoki, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Noriyo Yamashiki, Norihiro Kokudo

ABSTRACT

BackgroundNew-onset diabetes mellitus (NODM) after liver transplantation is a common complication with a potentially negative impact on patient outcome.MethodsTo evaluate the incidence of NODM and its impact on Asian adult living donor liver transplant (LDLT) recipients, we investigated 369 adult LDLT cases in our institute.ResultsPreoperative diabetes mellitus (DM) was diagnosed in 38 (9 %) patients. NODM was observed in 128/331 (38 %) patients, 56 (44 %) with persistent NODM and 72 (56 %) with transient NODM. The mean interval between LDLT and the development of NODM was 0.6 ± 1.8 (range 0–1.4) months. Multivariate analyssis revealed that older age, being male and having a higher body mass index were independent risk factors among recipients for developing NODM, while hepatitis C virus infection was not a significant risk factor, and DM had no impact on patient outcome.ConclusionsAlthough the long-term effect of DM on outcome remains to be investigated, the presence of DM after liver transplant, whether it was NODM or preexisting DM, had no impact on LDLT recipients’ outcomes in mid-term. More... »

PAGES

634-638

References to SciGraph publications

  • 2003-02. Living-donor liver transplantation in adults: Tokyo University experience in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00534-013-0602-6

    DOI

    http://dx.doi.org/10.1007/s00534-013-0602-6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1006588056

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/23564193


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