Treatment strategy for acute pancreatitis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-12-11

AUTHORS

Keita Wada, Tadahiro Takada, Koichi Hirata, Toshihiko Mayumi, Masahiro Yoshida, Masamichi Yokoe, Seiki Kiriyama, Masahiko Hirota, Yasutoshi Kimura, Kazunori Takeda, Shinju Arata, Morihisa Hirota, Miho Sekimoto, Shuji Isaji, Yoshifumi Takeyama, Toshifumi Gabata, Nobuya Kitamura, Hodaka Amano

ABSTRACT

When a diagnosis of acute pancreatitis (AP) is made, fundamental medical treatment consisting of fasting, intravenous (IV) fluid replacement, and analgesics with a close monitoring of vital signs should be immediately started. In parallel with fundamental medical treatment, assessment of severity based on clinical signs, blood test, urinalysis and imaging tests should be performed to determine the way of treatment for each patient. A repeat evaluation of severity is important since the condition is unstable especially in the early stage of AP. At the time of initial diagnosis, the etiology should be investigated by means of blood test, urinalysis and diagnostic imaging. If a biliary pancreatitis accompanied with acute cholangitis or biliary stasis is diagnosed or suspected, an early endoscopic retrograde cholangiopancreatography with or without endoscopic sphincterotomy (ERCP/ES) is recommended in addition to the fundamental medical treatment. In mild cases, the fundamental medical treatment should be continued until clinical symptom is subsided with normal laboratory data. In cases with severe acute pancreatitis (SAP) referral should be considered to medical centers experienced in the treatment of SAP, and intensive care is recommended for preventing both organ failures and infectious complications. Hemodynamic stabilization with vigorous fluid resuscitation, respiratory support and antibiotics are the major parts of intensive care in the early period of SAP. Continuous hemodiafiltration (CHDF) and continuous regional arterial infusion (CRAI) of protease inhibitor and/or antibiotics may be effective to improve pathophysiology of AP especially in the early stage of the disease. In the late stage of AP, infectious complications are critical. If an infectious complication is suspected based on clinical signs, blood test and imaging, a fine needle aspiration (FNA) is recommended to establish a diagnosis. The accuracy of FNA is reported to be 89 ~ 100%. For patients with sterile pancreatitis, non-surgical treatment should be indicated. For patients with infected pancreatic necrosis, therapeutic intervention either by percutaneous, endoscopic, laparoscopic or surgical approach are indicated. The most preferred surgical intervention is necrosectomy, however, non-surgical treatment with antibiotics is still the treatment of choice if the general condition is stable. Necrosectomy should be performed as late as possible. For patients with pancreatic abscess, drainage is recommended. More... »

PAGES

79-86

References to SciGraph publications

  • 1985-10. Death due to acute pancreatitis in DIGESTIVE DISEASES AND SCIENCES
  • 2006-02. JPN Guidelines for the management of acute pancreatitis: severity assessment of acute pancreatitis in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 2006-02. JPN Guidelines for the management of acute pancreatitis: medical management of acute pancreatitis in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 2006-02. JPN Guidelines for the management of acute pancreatitis:surgical management in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 2006-10-01. Practice Guidelines in Acute Pancreatitis in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2006-06-01. Timing of Antibiotic Prophylaxis in Acute Pancreatitis: A Controlled Randomized Study with Meropenem in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 1981-01. Controlled trial of cimetidine in acute pancreatitis in EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
  • 2006-02. JPN Guidelines for the management of acute pancreatitis: epidemiology, etiology, natural history, and outcome predictors in acute pancreatitis in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 2006-02. JPN Guidelines for the management of acute pancreatitis: treatment of gallstone-induced acute pancreatitis in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 1979-05. Nasogastric suction in alcoholic pancreatitis in DIGESTIVE DISEASES AND SCIENCES
  • 2004-08-26. Endoscopic sphincterotomy for prevention of the recurrence of acute biliary pancreatitis in patients with gallbladder in situ: long-term follow-up of 88 patients in SURGICAL ENDOSCOPY
  • 1999-11-01. Metaanalysis of randomized controlled trials of endoscopic retrograde cholangiography and endoscopic sphincterotomy for the treatment of acute biliary pancreatitis in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2007-10-09. Prophylactic Antibiotics Cannot Reduce Infected Pancreatic Necrosis and Mortality in Acute Necrotizing Pancreatitis: Evidence From a Meta-Analysis of Randomized Controlled Trials in THE AMERICAN JOURNAL OF GASTROENTEROLOGY
  • 2006-09-07. Pro/con debate: Antifungal prophylaxis is important to prevent fungal infection in patients with acute necrotizing pancreatitis receiving broad-spectrum antibiotics in CRITICAL CARE
  • 1982-12. A randomized trial comparing cimetidine to nasogastric suction in acute pancreatitis in DIGESTIVE DISEASES AND SCIENCES
  • 1995-12. CT-guided aspiration of suspected pancreatic infection in JOURNAL OF GASTROINTESTINAL CANCER
  • 1994-04. Indications for surgery in severe acute pancreatitis in JOURNAL OF GASTROINTESTINAL CANCER
  • 2000-10. Does mortality occur early or late in acute pancreatitis? in JOURNAL OF GASTROINTESTINAL CANCER
  • 2006-02. JPN Guidelines for the management of acute pancreatitis: diagnostic criteria for acute pancreatitis in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 2006-02. JPN Guidelines for the management of acute pancreatitis: cutting-edge information in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • Journal

    Author Affiliations

  • Department of Surgery, Teikyo University School of Medicine, 2-11-1, Kaga-cho, 173, Itabashi, Tokyo, Japan
  • Department of Surgical Oncology and Gastroenterological Surgery, Sapporo Medical University Graduate School of Medicine, Sapporo, Japan
  • Department of Emergency and Critical Care Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
  • Department of Hemodialysis and Surgery, Clinical Research Center Kaken Hospital, International University of Health and Welfare, Chiba, Japan
  • General Internal Medicine, Japanese Red Cross Society Nagoya Daini Hospital, Nagoya, Japan
  • Department of Gastroenterology, Ogaki Municipal Hospital, Ogaki, Japan
  • Department of Surgery, Kumamoto Regional Medical Center, Kumamoto, Japan
  • Department of Surgery, National Hospital Organization Sendai Medical Center, Sendai, Japan
  • Critical Care and Emergency Center, Yokohama City University Medical Center, Yokohama, Japan
  • Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan
  • Department of Healthcare Economics and Quality Management, Kyoto University Graduate School of Medicine, Kyoto, Japan
  • Department of Hepatobiliary Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Mie, Japan
  • Department of Surgery, Kinki University School of Medicine, Osaka, Japan
  • Department of Radiology, Graduate School of Medical Science, Kanazawa University, Ishikawa, Japan
  • Department of Emergency and Critical Care Medicine, Kimitsu Chuo Hospital, Chiba, Japan
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00534-009-0218-z

    DOI

    http://dx.doi.org/10.1007/s00534-009-0218-z

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1032563164

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20012325


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