Liver failure after major hepatic resection View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-03

AUTHORS

Giuseppe Garcea, G. J. Maddern

ABSTRACT

INTRODUCTION: The consequence of excessive liver resection is the inexorable development of progressive liver failure characterised by the typical stigmata associated with this condition, including worsening coagulopathy, hyperbilirubinaemia and encephalopathy. The focus of this review will be to investigate factors contributing to hepatocyte loss and impaired regeneration. METHODS: A literature search was undertaken of Pubmed and related search engines, examining for articles relating to hepatic failure following major hepatectomy. RESULTS: In spite of improvements in adjuvant chemotherapy and increasing surgical confidence and expertise, the parameters determining how much liver can be resected have remained largely unchanged. A number of preoperative, intraoperative and post-operative factors all contribute to the likelihood of liver failure after surgery. CONCLUSIONS: Given the magnitude of the surgery, mortality and morbidity rates are extremely good. Careful patient selection and preservation of an obligate volume of remnant liver is essential. Modifiable causes of hepatic failure include avoidance of sepsis, drainage of cholestasis with restoration of enteric bile salts and judicious use of portal triad inflow occlusion intra-operatively. Avoidance of post-operative sepsis is most likely to be achieved by patient selection, meticulous intra-operative technique and post-operative care. Modulation of portal vein pressures post-operatively may further help reduce the risk of liver failure. More... »

PAGES

145-155

References to SciGraph publications

  • 2006-11. Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine in WORLD JOURNAL OF SURGERY
  • 2008-01. Preoperative biliary drainage for biliary tract and ampullary carcinomas in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 1994. Causes of death in patients undergoing liver surgery in HEPATOBILIARY CANCER
  • 2002-02. Diabetes is associated with increased perioperative mortality but equivalent long-term outcome after hepatic resection for colorectal cancer in JOURNAL OF GASTROINTESTINAL SURGERY
  • 1994-01. Doppler analysis of hepatic blood flow predicts liver dysfunction after major hepatectomy in WORLD JOURNAL OF SURGERY
  • 1990-01. Can hepatic failure after surgery for hepatocellular carcinoma in cirrhotic patients be prevented? in WORLD JOURNAL OF SURGERY
  • 1992-12. Liver regeneration following portacaval shunt in rats: 3′, 5′-cyclic AMP changes in plasma and liver tissue in RESEARCH IN EXPERIMENTAL MEDICINE
  • 2004-10. Liver regeneration: from myth to mechanism in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 1995-01. Resection of colorectal liver metastases in WORLD JOURNAL OF SURGERY
  • 1999-09. Immediate increase of portal pressure, reflecting sinusoidal shear stress, induced liver regeneration after partial hepatectomy in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 2007-03. Mechanism of impaired hepatic regeneration in cholestatic liver in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 2001-09. Regeneration of Liver with Marked Fatty Change Following Partial Hepatectomy in Rats in DIGESTIVE DISEASES AND SCIENCES
  • 1999-01. Role of shear stress and immune responses in liver regeneration after a partial hepatectomy in SURGERY TODAY
  • 2006-04. Surgical resection of hepatic metastases from colorectal cancer: A systematic review of published studies in BRITISH JOURNAL OF CANCER
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00534-008-0017-y

    DOI

    http://dx.doi.org/10.1007/s00534-008-0017-y

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1027746735

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19110651


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