Diagnosis of biliary tract and ampullary carcinomas View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-01

AUTHORS

Kazuhiro Tsukada, Tadahiro Takada, Masaru Miyazaki, Shuichi Miyakawa, Masato Nagino, Satoshi Kondo, Junji Furuse, Hiroya Saito, Toshio Tsuyuguchi, Fumio Kimura, Hideyuki Yoshitomi, Satoshi Nozawa, Masahiro Yoshida, Keita Wada, Hodaka Amano, Fumihiko Miura

ABSTRACT

Diagnostic methods for biliary tract carcinoma and the efficacy of these methods are discussed. Neither definite methods for early diagnosis nor specific markers are available in this disease. When this disease is suspected on the basis of clinical symptoms and risk factors, hemato-biochemical examination and abdominal ultrasonography are performed and, where appropriate, enhanced computed tomography (CT) and/or magnetic resonance cholangiopancreatography (MRCP) is carried out. Diagnoses of extrahepatic bile duct cancer and ampullary carcinoma are often made based on the presence of obstructive jaundice. Although rare, abdominal pain and pyrexia, as well as abnormal findings of the hepatobiliary system detected by hemato-biochemical examination, serve as a clue to making a diagnosis of these diseases. On the other hand, the early diagnosis of gallbladder cancer is scarcely possible on the basis of clinical symptoms, so when this cancer is found with the onset of abdominal pain and jaundice, it is already advanced at the time of detection, thus making a cure difficult. When gallbladder cancer is suspected, enhanced CT is carried out. Multidetector computed tomography (MDCT), in particular--one of the methods of enhanced CT--is useful for decision of surgical criteria, because MDCT shows findings such as localization and extension of the tumor, and the presence or absence of remote metastasis. Procedures such as magnetic resonance imaging, endoscopic ultrasonography, bile duct biopsy, and cholangioscopy should be carried out taking into account indications for these procedures in individual patients. However, direct biliary tract imaging is necessary for making a precise diagnosis of the horizontal extension of bile duct cancer. More... »

PAGES

31-40

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00534-007-1278-6

DOI

http://dx.doi.org/10.1007/s00534-007-1278-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1035311616

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18274842


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22 schema:description Diagnostic methods for biliary tract carcinoma and the efficacy of these methods are discussed. Neither definite methods for early diagnosis nor specific markers are available in this disease. When this disease is suspected on the basis of clinical symptoms and risk factors, hemato-biochemical examination and abdominal ultrasonography are performed and, where appropriate, enhanced computed tomography (CT) and/or magnetic resonance cholangiopancreatography (MRCP) is carried out. Diagnoses of extrahepatic bile duct cancer and ampullary carcinoma are often made based on the presence of obstructive jaundice. Although rare, abdominal pain and pyrexia, as well as abnormal findings of the hepatobiliary system detected by hemato-biochemical examination, serve as a clue to making a diagnosis of these diseases. On the other hand, the early diagnosis of gallbladder cancer is scarcely possible on the basis of clinical symptoms, so when this cancer is found with the onset of abdominal pain and jaundice, it is already advanced at the time of detection, thus making a cure difficult. When gallbladder cancer is suspected, enhanced CT is carried out. Multidetector computed tomography (MDCT), in particular--one of the methods of enhanced CT--is useful for decision of surgical criteria, because MDCT shows findings such as localization and extension of the tumor, and the presence or absence of remote metastasis. Procedures such as magnetic resonance imaging, endoscopic ultrasonography, bile duct biopsy, and cholangioscopy should be carried out taking into account indications for these procedures in individual patients. However, direct biliary tract imaging is necessary for making a precise diagnosis of the horizontal extension of bile duct cancer.
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30 abdominal pain
31 abdominal ultrasonography
32 abnormal findings
33 absence
34 account indications
35 ampullary carcinoma
36 basis
37 bile duct cancer
38 biliary tract
39 biliary tract carcinoma
40 biliary tract imaging
41 biopsy
42 cancer
43 carcinoma
44 cholangiopancreatography
45 cholangioscopy
46 clinical symptoms
47 clues
48 computed tomography
49 criteria
50 cure
51 decisions
52 definite method
53 detection
54 diagnosis
55 diagnostic methods
56 direct biliary tract imaging
57 disease
58 duct biopsy
59 duct cancer
60 early diagnosis
61 efficacy
62 endoscopic ultrasonography
63 enhanced computed tomography
64 examination
65 extension
66 extrahepatic bile duct cancer
67 factors
68 findings
69 gallbladder cancer
70 hand
71 hemato-biochemical examination
72 hepatobiliary system
73 horizontal extension
74 imaging
75 indications
76 individual patients
77 jaundice
78 localization
79 magnetic resonance cholangiopancreatography
80 magnetic resonance imaging
81 markers
82 metastasis
83 method
84 multidetector
85 obstructive jaundice
86 onset
87 pain
88 patients
89 precise diagnosis
90 presence
91 procedure
92 pyrexia
93 remote metastasis
94 resonance cholangiopancreatography
95 resonance imaging
96 risk factors
97 specific markers
98 surgical criteria
99 symptoms
100 system
101 time
102 time of detection
103 tomography
104 tract
105 tract carcinoma
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